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Review: taking Coumadin and Methotrexate together

Summary: drug interactions are reported among people who take Coumadin and Methotrexate together.

This review analyzes the effectiveness and drug interactions between Coumadin and Methotrexate. It is created by eHealthMe based on reports of 2,171 people who take the same drugs from FDA and social media, and is updated regularly.

 

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On Mar, 27, 2015: 2,171 people who take Coumadin, Methotrexate are studied

Coumadin, Methotrexate outcomes

Drug combinations in study:
- Coumadin (warfarin sodium)
- Methotrexate (methotrexate sodium)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Coumadin is effective100.00%
(1 of 1 people)
50.00%
(2 of 4 people)
100.00%
(1 of 1 people)
75.00%
(3 of 4 people)
75.00%
(3 of 4 people)
100.00%
(3 of 3 people)
100.00%
(1 of 1 people)
n/a
Methotrexate is effective0.00%
(0 of 2 people)
0.00%
(0 of 2 people)
100.00%
(2 of 2 people)
40.00%
(2 of 5 people)
0.00%
(0 of 3 people)
25.00%
(1 of 4 people)
100.00%
(1 of 1 people)
n/a

Drug effectiveness by gender :

FemaleMale
Coumadin is effective72.73%
(8 of 11 people)
85.71%
(6 of 7 people)
Methotrexate is effective25.00%
(3 of 12 people)
42.86%
(3 of 7 people)

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Coumadin is effectiven/an/an/an/a100.00%
(1 of 1 people)
66.67%
(2 of 3 people)
20.00%
(3 of 15 people)
53.33%
(8 of 15 people)
Methotrexate is effectiven/an/an/an/a0.00%
(0 of 1 people)
0.00%
(0 of 2 people)
5.13%
(2 of 39 people)
26.67%
(4 of 15 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
FallAnaemiaVomitingPulmonary EmbolismPancytopeniaWeight DecreasedOedema PeripheralAtrial Fibrillation
StomatitisThrombocytopeniaDecreased AppetiteDiverticulum Intestinal HaemorrhagicDizzinessPyrexiaDyspnoeaPain
PyrexiaGastrointestinal HaemorrhageInflammationVomitingInterstitial Lung DiseaseFacial ParesisAtrial FibrillationDyspnoea
International Normalised Ratio IncreasedConfusional StateAtrial FibrillationPneumoniaBalance DisorderCoughAutoimmune HepatitisPneumonia
ConstipationHaemolytic AnaemiaChest PainVulval CellulitisSquamous Cell CarcinomaSquamous Cell CarcinomaHepatic CirrhosisArthralgia
Platelet Count DecreasedInternational Normalised Ratio DecreasedLiver DisorderNauseaRheumatoid ArthritisHiatus HerniaPancreatitis AcuteAnaemia
Non-hodgkin's LymphomaNeuropathy PeripheralNauseaDiarrhoeaDental CariesPneumoniaLactose IntoleranceAsthenia
Deep Vein ThrombosisFallHerpes OesophagitisDeep Vein ThrombosisDeep Vein ThrombosisMetastases To Central Nervous SystemAstheniaFatigue
C-reactive Protein IncreasedCardiac Failure CongestiveHerpes Virus InfectionCerebrovascular AccidentMyelodysplastic SyndromeLung Cancer MetastaticCardiac Failure ChronicPyrexia
ArrhythmiaPalmar-plantar Erythrodysaesthesia SyndromeViral InfectionAlopeciaSepsis NosMuscle RigidityBlood Alkaline Phosphatase IncreasedFall

Most common drug interactions by gender * :

FemaleMale
PainPneumonia
Atrial FibrillationAtrial Fibrillation
DyspnoeaAsthenia
AnaemiaPyrexia
ArthralgiaDyspnoea
FallFatigue
PneumoniaPain
Pulmonary EmbolismChest Pain
AstheniaOedema Peripheral
NauseaCough

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/an/aVomitingCondition AggravatedArthralgiaPainFatigueAtrial Fibrillation
Infusion Related ReactionWegener's GranulomatosisPneumoniaDepressionDyspnoeaAsthenia
HeadachePancytopeniaNauseaAnxietyArthralgiaPneumonia
PneumoniaInternational Normalised Ratio IncreasedVenous ThrombosisFatigueAtrial FibrillationPain
ScoliosisAbscessVentricular TachycardiaPulmonary EmbolismCoughFall
Crohn's DiseaseWeight IncreasedPyrexiaPyrexiaDyspnoea
Drug IneffectiveAcute Right Ventricular FailureIntervertebral Disc ProtrusionPainAnaemia
Aspartate Aminotransferase IncreasedPharyngeal OedemaOsteonecrosis Of JawAnaemiaArthralgia
Abdominal PainUrticariaFallRheumatoid ArthritisPyrexia
Diarrhoea HaemorrhagicAnaemiaAnaemiaNauseaChest Pain

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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- support group for people who take Coumadin
- support group for people who take Methotrexate

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Coumadin (warfarin sodium) is often used to treat blood clots. Methotrexate (methotrexate sodium) is often used to treat rheumatoid arthritis. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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