Review: Coumadin and Norvasc
Summary: drug interactions are reported among people who take Coumadin and Norvasc together.
This review analyzes the effectiveness and drug interactions between Coumadin and Norvasc. It is created by eHealthMe based on reports of 6,851 people who take the same drugs from FDA and social media, and is updated regularly.
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Coumadin has active ingredients of warfarin sodium. It is often used in blood clots. (latest outcomes from Coumadin 75,095 users) Norvasc has active ingredients of amlodipine besylate. It is often used in high blood pressure. (latest outcomes from Norvasc 80,472 users)
What are the drugs
Coumadin has active ingredients of warfarin sodium. It is often used in blood clots. (latest outcomes from Coumadin 75,095 users)
Norvasc has active ingredients of amlodipine besylate. It is often used in high blood pressure. (latest outcomes from Norvasc 80,472 users)
On Nov, 26, 2014: 6,851 people who take Coumadin, Norvasc are studied
Drug combinations in study:
- Coumadin (warfarin sodium)
- Norvasc (amlodipine besylate)
Drug effectiveness over time :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years||not specified|
|Coumadin is effective||25.00%|
(2 of 8 people)
(7 of 15 people)
(4 of 6 people)
(7 of 11 people)
(13 of 17 people)
(6 of 11 people)
(14 of 15 people)
(1 of 1 people)
|Norvasc is effective||0.00%|
(0 of 3 people)
(3 of 13 people)
(2 of 6 people)
(4 of 18 people)
(11 of 19 people)
(10 of 17 people)
(6 of 10 people)
(0 of 1 people)
Most common drug interactions over time * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years||not specified|
|International Normalised Ratio Increased||Dyspnoea||Dyspnoea||Nephrogenic Systemic Fibrosis||Dyspnoea||Pain||International Normalised Ratio Increased||Pain|
|Dyspnoea||Oedema Peripheral||Dizziness||Syncope||Deep Vein Thrombosis||Anxiety||Haemoglobin Decreased||Oedema Peripheral|
|Gastrointestinal Haemorrhage||Myocardial Infarction||Renal Failure Acute||Anxiety||International Normalised Ratio Increased||General Physical Health Deterioration||Gingival Bleeding||Dyspnoea|
|Renal Failure Acute||Anxiety||Fall||Oedema Peripheral||Anxiety||Nephrogenic Systemic Fibrosis||Occult Blood Positive||Atrial Fibrillation|
|Haemoglobin Decreased||Cardiac Failure Congestive||Atrial Fibrillation||Pain||Pulmonary Haemorrhage||Mobility Decreased||Dizziness||Anxiety|
|Renal Failure||Cellulitis||Bradycardia||Asthenia||Pneumonia||Rash||Gastric Cancer||International Normalised Ratio Increased|
|Bradycardia||Transient Ischaemic Attack||Intervertebral Disc Displacement||Hypoaesthesia||Dyspnoea Exertional||Major Depression||Upper Gastrointestinal Haemorrhage||Nausea|
|Oedema||Headache||Ear Disorder||Extremity Contracture||Hypoxia||Injury||Coagulopathy||Asthenia|
|Hypokalaemia||Haemorrhoids||Flushing||Hepatic Function Abnormal||Circulatory Collapse||Skin Disorder||Melaena||Fatigue|
|Thrombosis||Emotional Distress||Groin Pain||Rhabdomyolysis||Cardiac Failure||Emotional Distress||Pulmonary Embolism||Cardiac Failure Congestive|
Drug effectiveness by gender :
|Coumadin is effective||46.88%|
(15 of 32 people)
(39 of 52 people)
|Norvasc is effective||37.50%|
(12 of 32 people)
(24 of 55 people)
Most common drug interactions by gender * :
|Atrial Fibrillation||Cardiac Failure Congestive|
|Oedema Peripheral||International Normalised Ratio Increased|
|International Normalised Ratio Increased||Atrial Fibrillation|
Drug effectiveness by age :
|Coumadin is effective||n/a||n/a||n/a||n/a||n/a||30.00%|
(3 of 10 people)
(12 of 21 people)
(39 of 93 people)
|Norvasc is effective||n/a||n/a||n/a||n/a||n/a||10.00%|
(1 of 10 people)
(4 of 18 people)
(31 of 104 people)
Most common drug interactions by age * :
|Pleural Effusion||Hallucination, Visual||Subdural Haematoma||Pain||Pain||Oedema Peripheral||Pain||Atrial Fibrillation|
|Hepatic Function Abnormal||Road Traffic Accident||Syncope||Nephrogenic Systemic Fibrosis||Nephrogenic Systemic Fibrosis||International Normalised Ratio Increased||Anxiety||International Normalised Ratio Increased|
|Disseminated Intravascular Coagulation||Sleep Disorder||Lower Gastrointestinal Haemorrhage||Skin Tightness||Anxiety||Dyspnoea||Oedema Peripheral||Pain|
|Rhabdomyolysis||Tachycardia||Varicella||Oedema Peripheral||Skin Induration||Erythema||Nausea||Asthenia|
|Pyrexia||Feeling Abnormal||Diarrhoea||Mobility Decreased||Skin Tightness||Pain||Depression||Dyspnoea|
|Pneumonia||Tremor||Back Pain||Oedema||Fibrosis||Nephrogenic Systemic Fibrosis||Dyspnoea||Nausea|
|Pulmonary Hypertension||Confusional State||Skull Fracture||Skin Hyperpigmentation||Renal Failure||Cellulitis||Nephrogenic Systemic Fibrosis||Cardiac Failure Congestive|
|Anaemia||Fall||Contusion||Skin Disorder||Skin Hypertrophy||Arthralgia||Pain In Extremity||Oedema Peripheral|
|Abortion Spontaneous Nos||Constipation||Arthralgia||Skin Depigmentation||Emotional Distress||Fatigue||Anaemia||Anaemia|
|Paternal Drugs Affecting Foetus||Contusion||Peroneal Nerve Palsy||Chest Pain||Pain In Extremity||Muscular Weakness||Fatigue|
* Some reports may have incomplete information.
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You are not alone! Join a related mobile support group:
- support group for people who take Coumadin and Norvasc
- support group for people who take Coumadin
- support group for people who take Norvasc
Can you answer these questions (Ask a question):
- I need a prostrate medication that will not interact with warfarin.
I need to keep the INR level to 2.5 and don't want to change that regimin
- Since starting coumadin i am exhausted all the time and have muscle and joint pain. (1 answer)
In 2012 I had two PE's and four DVT's; I was diagnosed with a clotting disorder; after several hospitalizations they put an IVC filter in. Within a few months I was diagnosed with RA, Rheumatoid Arthritis. I am chronically exhausted, I have muscle pain - sometimes the pain in my upper legs/thighs is so severe I have lift my leg with my hands to get it into the car. Overtime I lost my livelihood and have become very depressed. Doctors say these symtoms are not related to any of the drugs I am taking.
- My mother was heart patient .mitral valve changed with metallic valve in 1999. now she is suffering from golbladder stone. is it possible to do next surgery or what is the treatment suggestion . (2 answers)
My mother was heart patient.Mitral valve changed with metallic valve in 1999. now she is suffering from gollbladder stone.Due to this some time she is feeling pain sometimes. Is it possible to do next surgery or what is the treatment suggestion Please repply.
- Can unexplained hypertension be cause by a partial thyroidectomy?
Doc is trying to figure out why the BP suddenly spiked. I started an exercise regimen after a stress test. I had to be on Metoprolol just to pass the test. Results were no heart-related issues. Lost 6lbs. since starting exercise and don't know if this is Thyroidal or not. No discussion with the doc yet of whether this is related to the thyroidectomy of the past.
- Can warfarin cause prolonged chest infections?
I have been on Warfarin for 3 years because of atrial fibrillation, and coincidentally or not, since then I have had a chronic chest infection which never clears. I have had scores of antibiotics which have not helped at all. When I cough I sound like I smoke 60 cigarettes daily, I have never smoked in my life. I sound like someone who has cystic fibrosis or COPD. My doctors never seem concerned that this has gone on so long, they just tell me I need to go on more holidays in the sunshine! It's getting me and my family down, and I don't know what to do.
You may be interested at these reviews (Write a review):
- Bloody semen after taking amlodipine besylate
Was started on Amlodipine Besylate 11-13-14. Now -not quite three weeks later- I have bloody semen (Hematospermia)ranging from light pink to dark red. It was fine, and normal before. I feel it is the medication causing this.
- Amlo dipine and terazosin
I have taken combination since 04/13 I have experienced ED lower testosterone and elevated PSA. Prior to that I was taking terazosin and hydrochorizide without any side effects. I stop taking the amlodipine during a juice fast and my PSA levels decreased when I stopped fasting and returned to taking the amlodipine my PSA levels rose.
- Had nms in 2005, will trileptal increase chance of recurrence?
In 2005 I had NMS, which was not detected by my drs for 4 months. I'd been on Lexapro & Seroquel for 2 yrs, but was weaned from Lexapro & placed on Lamictal 3/05. Began getting low-grade fevers, which I was told were not caused by the Lamictal. I quit taking it anyway, fevers (along with uncontrollable shivering) continued & got higher. By 5/05 my temps were reaching 105 deg F. Husband said I became combative, refused to go to hospital. Early June/05 he came home to find me wrapped in blankets, with a temp over 105 F. He tried to place me in a tub of cold water, said I was rigid & screamed when he tried to move me. I was in the tub, speaking "in tongues" (his description, I have no memory of this). He called 911, took me to hospital. I woke, no idea where I was or why. After a lumbar puncture & 2 days in ICU I went home. The fevers continued...2 weeks later he came home to find me wrapped in sheets, towels, blankets, with the heat on full (it was in the 90's outside) he called ambulance again. I awoke to find myself under an ice blanket with nurses pushing large vials of dantrolene into both arms, several liters. Another LP, a stint in ICU...this time they told me it was NMS. The dr who dxd me said he was surprised I was alive, & not a vegetable, as my temp had peaked at 109 deg F. I suffered brain damage; short-term memory loss, brain can't control my body temp, my blood pressure went up. An arteriogram showed completely healthy heart & arteries, no plaque at all. I lost all body fat as well as some muscle mass. The fevers continued even after stopping the Seroquel. I visited my PCP for a checkup in 9/05, temp was normal. I started shuddering, my temp went up a full degree every 5 minutes. PCP admitted me to ER, my heart rate was over 272 B/M; they stopped my heart 3 times to "reset" it, which didn't work. I spent 3 days in hospital. Several months later my P doc tried me on Lamictal alone; I got Stevens-Johnson syndrome. I stopped the drug as soon as the signs appeared. I've been untreated, except for Neurontin & Primidone, until my manic episodes became unlivable. 3 weeks ago I went 8 days with no sleep, became psychotic. My P doc gave me Trileptal, which has evened my moods, but I've been getting low-grade fevers (highest was 103.6). Would having had NMS in the past make me more prone to falling to it again with the Trileptal? It's the only new med I've taken in over a year.
- Not a great experience
I was on norvasc for two months and had to go off because of severe swelling of feet and legs. Also rapid heart beat and very profuse sweating. it was horrible. It also raised my blood pressure. after going off BP dropped by @least 10 points both diastolic and systolic.
- High blood pressure - find the right medication (2 responses)
I was going through the menopause with all the usual drama when I started feeling awful. Doc said that my blood pressure was through the roof and prescribed Lisinopril. This gave me technicolour dreams and a runny nose, so he switched me to Losartan. This made me soooo tired that I didn't want to get up. So then I tried Amlopidine. Fantastic! I haven't felt this well since I was on my teens. My message is ... don't put up with side effects. Change your drug until you find the one that works for you.
Comments from related studies:
From this study (5 months ago):
From this study (12 months ago):
From this study (2 years ago):
increased level of crestor and decreased level of furosemide and heart rate has increased
Family history of stroke on Father and Uncles side. Brief thyroid problem. History-- infrequent use of anti-depressants during teens to 30's---Stelazine, Mellaril. My Fathers Mother was treated for Manic-depression after 30-82yo.
Triple bypass march 2011 , Aortic valve replacement march 2011 (mechanical), sleep apnea, optic migraines
Complete drug side effects:
On eHealthMe, Coumadin (warfarin sodium) is often used to treat blood clots. Norvasc (amlodipine besylate) is often used to treat high blood pressure. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.
What is the drug used for and how effective is it:
- Coumadin is used in:
- Norvasc is used in:
Other drugs that are used to treat the same conditions:
- Coumadin alternatives:
- Norvasc alternatives:
NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
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