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Review: taking Coumadin and Phenytoin together

Summary: drug interactions are reported among people who take Coumadin and Phenytoin together.

This review analyzes the effectiveness and drug interactions between Coumadin and Phenytoin. It is created by eHealthMe based on reports of 1,438 people who take the same drugs from FDA and social media, and is updated regularly.


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On Mar, 23, 2015: 1,438 people who take Coumadin, Phenytoin are studied

Coumadin, Phenytoin outcomes

Drug combinations in study:
- Coumadin (warfarin sodium)
- Phenytoin (phenytoin)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Coumadin is effectiven/a100.00%
(1 of 1 people)
Phenytoin is effectiven/a100.00%
(1 of 1 people)

Drug effectiveness by gender :

Coumadin is effective100.00%
(1 of 1 people)
Phenytoin is effective100.00%
(1 of 1 people)

Drug effectiveness by age :

Coumadin is effectiven/an/an/an/an/an/a33.33%
(1 of 3 people)
Phenytoin is effectiven/an/an/an/an/an/a33.33%
(1 of 3 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
International Normalised Ratio IncreasedStevens-johnson SyndromeBrain HerniationStress SymptomsConfusional StateConvulsionLupus-like SyndromeConvulsion
Transaminases IncreasedInternational Normalised Ratio IncreasedDrug Level IncreasedHepatitis NosHaemorrhagic StrokeAnticonvulsant Drug Level DecreasedArthritisInternational Normalised Ratio Increased
Hereditary AngioedemaHepatic FailureFallBlood Viscosity IncreasedHeadachePleural EffusionDrug IneffectivePain
Urinary Tract InfectionDeliriumSubdural HaematomaCerebral Artery EmbolismPulmonary HypertensionStatus EpilepticusFall
PancreatitisRashDeathCerebral HaemorrhagePost Procedural ComplicationGrand Mal ConvulsionAsthenia
ConvulsionHepatorenal SyndromeSpeech DisorderAphasiaPhlebothrombosisMalaiseDyspnoea
Status EpilepticusConvulsionAnaemia NosScreamingLimb InjuryNormal Pressure HydrocephalusAnxiety
Stevens-johnson SyndromePruritusWeight DecreasedTardive DyskinesiaPacemaker ComplicationOedema PeripheralPneumonia
Anticonvulsant Drug Level DecreasedCardiomegalyHaemorrhagic StrokeUrine Calcium IncreasedPulmonary ThrombosisCardiac FibrillationHeadache
Ear InfectionHyperthyroidismPalpitationsDelusion NosSleep Apnoea SyndromeBlood Cholesterol IncreasedOedema Peripheral

Most common drug interactions by gender * :

AstheniaInternational Normalised Ratio Increased
ConvulsionOedema Peripheral
Bone DisorderConfusional State
AnxietyDeep Vein Thrombosis
International Normalised Ratio IncreasedRenal Failure

Most common drug interactions by age * :

WeaknessThrombocytopeniaInternational Normalised Ratio IncreasedNephrogenic Systemic FibrosisPainDeep Vein ThrombosisInternational Normalised Ratio IncreasedConvulsion
SedationMucosal HaemorrhageStevens-johnson SyndromeSkin DepigmentationOedema PeripheralConfusional StatePainInternational Normalised Ratio Increased
InjuryThrombosisPeroneal Nerve PalsySkin HypertrophyCytokine StormArthralgiaFall
DeathConvulsionMobility DecreasedMyocardial InfarctionDeliriumBronchitisPain
Megakaryocytes IncreasedSuperior Sagittal Sinus ThrombosisSkin TightnessNephrogenic Systemic FibrosisPetechiaeAnxietyDepression
PetechiaeThalamic InfarctionPainSkin TightnessImpetigoFallAsthenia
Multi-organ FailureThrombosis NosDry SkinJoint ContractureBody Temperature IncreasedConvulsionHeadache
Platelet Destruction IncreasedPhantom Limb PainSubcutaneous NoduleJoint Range Of Motion DecreasedConvulsionOedema PeripheralDyspnoea
DepressionHaematemesisSkin WarmPruritusInternational Normalised Ratio IncreasedBack PainAnxiety
AnxietyCondition AggravatedHyperkeratosisAnxietyChest PainRenal FailureSwelling

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Coumadin and Phenytoin?




You are not alone! Join a related support group:
- support group for people who take Coumadin
- support group for people who take Phenytoin

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Coumadin (warfarin sodium) is often used to treat blood clots. Phenytoin (phenytoin) is often used to treat epilepsy. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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