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Review: Coumadin and Savella





Summary: drug interactions are reported among people who take Coumadin and Savella together.

This review analyzes the effectiveness and drug interactions between Coumadin and Savella. It is created by eHealthMe based on reports of 72 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Coumadin and Savella >>>

What are the drugs

Coumadin has active ingredients of warfarin sodium. It is often used in blood clots. (latest outcomes from Coumadin 75,095 users)

Savella has active ingredients of milnacipran hydrochloride. It is often used in fibromyalgia. (latest outcomes from Savella 3,389 users)

On Nov, 26, 2014: 72 people who take Coumadin, Savella are studied

Coumadin, Savella outcomes

Drug combinations in study:
- Coumadin (warfarin sodium)
- Savella (milnacipran hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Coumadin is effectiven/an/a0.00%
(0 of 1 people)
n/a0.00%
(0 of 1 people)
n/a100.00%
(1 of 1 people)
n/a
Savella is effectiven/a0.00%
(0 of 2 people)
50.00%
(1 of 2 people)
n/an/an/an/an/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
NauseaHeart Rate IrregularDysphagian/an/an/an/aNausea
HyperhidrosisNauseaHeart Rate IrregularHeadache
DizzinessSerotonin SyndromeHyperhidrosisHyperhidrosis
Heart Rate IrregularDysphagiaDizzinessDepression
Chest DiscomfortHyperhidrosisSerotonin SyndromeDizziness
Serotonin SyndromeDizzinessChest PainDysphagia
DysphagiaBlood Pressure IncreasedBlood Pressure IncreasedVomiting
Chest PainChest DiscomfortChest DiscomfortInternational Normalised Ratio Increased
Blood Pressure IncreasedChest PainNauseaHeart Rate Irregular
Dermatitis ExfoliativeDecreased AppetiteFatigueSerotonin Syndrome

Drug effectiveness by gender :

FemaleMale
Coumadin is effective33.33%
(1 of 3 people)
n/a
Savella is effective25.00%
(1 of 4 people)
n/a

Most common drug interactions by gender * :

FemaleMale
NauseaSuicidal Ideation
HeadacheGastrointestinal Haemorrhage
HyperhidrosisInternational Normalised Ratio Increased
DepressionAsthenia
DizzinessHypersomnia
DysphagiaRib Fracture
VomitingFall
Blood Pressure IncreasedHyperhidrosis
Heart Rate IrregularFeeling Cold
Chest PainGait Disturbance

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Coumadin is effectiven/an/an/an/an/a100.00%
(1 of 1 people)
n/a0.00%
(0 of 2 people)
Savella is effectiven/an/an/an/an/a50.00%
(1 of 2 people)
n/a0.00%
(0 of 2 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/an/an/aPsychiatric DecompensationDrug Screen PositiveNauseaHeadacheNausea
Transfusion ReactionCellulitisVomitingNauseaHyperhidrosis
DepressionTachycardiaAnaphylactic ShockInternational Normalised Ratio IncreasedDysphagia
AlopeciaDiarrhoeaSwelling FaceDepression
HaemolysisDermatitis ExfoliativeSuicidal IdeationDizziness
Pain In ExtremityWeight DecreasedHomicidal IdeationHeart Rate Irregular
NauseaAdverse Drug ReactionDisturbance In AttentionSerotonin Syndrome
PresyncopeBasal Cell CarcinomaDizzinessBlood Pressure Increased
Muscular WeaknessSuicidal IdeationArthralgiaChest Pain
DyspnoeaNasal CystHeadache

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Coumadin and Savella?

You are not alone! Join a related mobile support group:
- support group for people who take Coumadin and Savella
- support group for people who take Coumadin
- support group for people who take Savella

Can you answer these questions (Ask a question):

More questions for: Coumadin, Savella

You may be interested at these reviews (Write a review):

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  • Nausea and vomiting while taking savella
    I have been on Savella for 6 months now and the nausea has increased with time and now I also have vomiting daily along with occasional diarrhea. I am currently weaning off of the Savella, cutting the dosage in half for two weeks and then one pill every other day for two weeks, following my dr.'s instructions. I have three weeks total left and still have the nausea and vomiting but hopeful that these will start to go away soon. Anyone else who has weaned off of it- how long until your symptoms subsided?
  • So sleepy with savella
    I am just finishing the starter pack of Savella and I am so sleepy I can't hold my head up. My pain and other Fibromyalgia symptoms are tremendously better but I am sleeping like crazy. Hopefully I can have both doses at night and this will help. I am so glad to not be in pain but I need to be awake also. I am going to talk to my doctor about perhaps another medication to help curb the sleepiness. I can't use caffeine or stimulants due to anxiety but need something to take this sleepiness away.
  • I wish i had never taken ambien
    Ambien was prescribed after my sleep study showed severe sleep latency and awakening. In the five hours I slept I woke 85 times and had only 5 minutes of deep sleep. However, the doctors couldn't make a recommendation because they could detect no cause for the poor sleep pattern. My doctor offered Ambien and since I had obviously needed the help sleeping I took it. For the next 10 years I suffered incredible depression. For example I remember laying in bed staring at the ceiling with tears rolling into my ears but I was too tired to wipe them away and realizing that I wanted to die so badly but there was no way I could have done anything about it. The worst effects were the loss of consciousness and the verbal abuse that I heaped on my husband and son. An example of each : I actually had sex with my husband that I could not remember amd hundreds of other actions and discussions. My husband started asking every morning what I remembered of the night before. He could usually tell when I was Ambien-awake (his name for it) he said my eyes would get glassy and my voice cadence would be off. Unfortunately my oldest son was going from infant to 8 years old at this time and any ifraction or even without provocation I would scream horrible things in his face. I don't remember much of it but what I do remember causes me enormous regret. He went from a happy and active toddler to a terrified amd anxious pre-teen. We are still working through the effects of this behavior. Finally, after a surprise pregnancy (see example above) My baby was placed in NICU and I stayed at the Ronald McDonald House and my son and husband visited when they could. Somehow my Ambien prescription was stopped and so I began going through withdrawal but I had no idea what was going on. My vision became so blurred thqt I couldn't identify items unless they were very large and then only by colors. When I visited my son those several days in the NICU I couldn't walk straight and would try to aim myself toward my goal until I hit a wall and I would correct course. These things didn't bother me at all but the nurses in the NICU were with me nearly the entire day because they were afraid I would have a stroke or who knew. Finally, after discussing these symptoms we decided to gradually stop the medication. Thankfully, i didn't have any withdrawal symptoms then. I did feel like an incredibly heavy and black blanket had been lifted away. Ever since I have had very little trouble with depression despite the continuation of sleep disturbance and pain. On a scale from one to 10 for depression with 10 being committing suicide I think my 10 years on the medicine was probably an 8.5 (I desperately wanted to die) and since stopping the medication I don't think it has gone above a 4 and is usually a 2 or 3. I will spend the rest of my life trying to repair the damage my verbal abuse caused my oldest son and my husband. For 10 years they lived in fear of my rages if I had a bad episode with Ambien.
  • Losartan cause deep vein thrombosis
    have had two knee surgeries ,a lumbar decompression, after this three surgeries start taken Losartan potassium and two months later have had a lumbar fusion after this I suffered a Deep Vein Thrombosis, continues taken Losartan for more of year and half, I notice is a bad combination when my older physician increase high dose of Warfarin I was losing mi Vision and stopped Losartan by my self and my vision is great now. my new physician told me that is OK that I had stopped taken Losartan. and I strongly believe that this cause me the DVT.

More reviews for: Coumadin, Savella

Comments from related studies:

  • From this study (2 years ago):

  • I have had a cat scan and some blood work and will be seeing a nuerologist next week' but I am looking for any information that can help me.

    Reply

  • From this study (5 years ago):

  • In spite of not eating green foods or taking NSAIDS, my INR is either way low or way high (1.3-6.1) I cannot seem to get this stabalized and have had increasing clotting in my left leg as a result. Could it be the tramadol? If so, what else could I take for fairly severe pain from arthritis and fibromyalgia? Thanks.

    Reply

Complete drug side effects:

On eHealthMe, Coumadin (warfarin sodium) is often used to treat blood clots. Savella (milnacipran hydrochloride) is often used to treat fibromyalgia. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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