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Review: taking Coumadin and Sudafed together

Summary: drug interactions are reported among people who take Coumadin and Sudafed together. This review analyzes the effectiveness and drug interactions between Coumadin and Sudafed. It is created by eHealthMe based on reports of 160 people who take the same drugs from FDA and social media, and is updated regularly.

Personalized health information: on eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA and social media since 1977. Our tools are free and anonymous. 66 million people have used us. 200+ peer-reviewed medical journals have referenced our original studies. Start now >>>


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What are the drugs

Coumadin has active ingredients of warfarin sodium. It is often used in blood clots. (latest outcomes from 75,118 Coumadin users)

Sudafed has active ingredients of pseudoephedrine hydrochloride. It is often used in sinus congestion. (latest outcomes from 5,171 Sudafed users)

On Apr, 29, 2015: 160 people who take Coumadin, Sudafed are studied

Coumadin, Sudafed outcomes

Drug combinations in study:
- Coumadin (warfarin sodium)
- Sudafed (pseudoephedrine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Coumadin is effective100.00%
(1 of 1 people)
(2 of 4 people)
(0 of 1 people)
(2 of 2 people)
(1 of 1 people)
(1 of 2 people)
Sudafed is effective57.14%
(4 of 7 people)
(1 of 1 people)
(0 of 1 people)
(0 of 1 people)
(0 of 2 people)
(1 of 1 people)

Drug effectiveness by gender :

Coumadin is effective66.67%
(4 of 6 people)
(3 of 5 people)
Sudafed is effective57.14%
(4 of 7 people)
(2 of 6 people)

Drug effectiveness by age :

Coumadin is effectiven/an/an/an/a33.33%
(1 of 3 people)
(3 of 8 people)
(1 of 2 people)
(2 of 2 people)
Sudafed is effectiven/an/an/an/a50.00%
(1 of 2 people)
(4 of 9 people)
(1 of 3 people)
(0 of 2 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Cerebrovascular AccidentInterstitial Lung DiseaseFatiguen/aInternational Normalised Ratio Increasedn/aNon-cardiac Chest PainSinusitis
InsomniaHeadacheParaesthesia OralNon-cardiac Chest PainExhaustion, Fatigue, Lethargy, Tiredness, WearinessOedema Peripheral
OliguriaPneumothoraxSkin WarmExhaustion, Fatigue, Lethargy, Tiredness, WearinessHeadachesComputerised Tomogram Abnormal
PyrexiaSacroiliitisVomitingHeadachesWeight Gain - UnintentionalTooth Disorder
Renal Failure AcuteUrinary Tract InfectionVena Cava ThrombosisWeight Gain - UnintentionalBack Pain
GoutInternational Normalised Ratio DecreasedOral DiscomfortAbscess
Blood Creatinine IncreasedMigraineArthralgiaPain
Vena Cava ThrombosisCervical CystErythemaFistula
International Normalised Ratio IncreasedNasal CongestionPain Of SkinInflammation
Dizziness AggravatedConstipationHypokalaemiaDepression

Most common drug interactions by gender * :

SinusitisRenal Failure
Computerised Tomogram AbnormalHyperglycaemia
Tooth DisorderOedema Peripheral
Back PainRespiratory Failure
AbscessDeep Vein Thrombosis
FistulaCardiac Failure Congestive
PainPleural Effusion
DepressionAtrial Fibrillation
Nasal CongestionInternational Normalised Ratio Increased

Most common drug interactions by age * :

n/an/aSkin WarmHeart Rate IncreasedUrinary Tract InfectionImpaired HealingSinusitisOedema Peripheral
FatigueAtrial FibrillationThrombosisHepatic CystOsteonecrosisNeck Pain
VomitingVomitingGlaucomaBack PainFatigue
Oral DiscomfortNasopharyngitisInflammationTooth DisorderAsthenia
Vena Cava ThrombosisNauseaLeft Ventricular HypertrophyAbdominal PainDepression
Paraesthesia OralSinusitisNasal CongestionSwelling FaceUrinary Tract Infection
ArthralgiaIntracardiac ThrombusMitral Valve IncompetenceAnorexiaAnaemia
HeadachePulmonary ThrombosisGingival BleedingTumour Marker IncreasedAtelectasis
Pain Of SkinInsomniaFistulaResorption Bone IncreasedDeep Vein Thrombosis
Decreased AppetiteHypertensionCholelithiasisRenal CystUpper Respiratory Tract Infection

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of Coumadin and Sudafed on

Do you take Coumadin and Sudafed?


You are not alone! Join a related support group:
- support group for people who take Coumadin
- support group for people who take Sudafed

Recent conversations of related support groups:

Can you answer these questions (Ask a question):

More questions for: Coumadin, Sudafed

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Complete drug side effects:

On eHealthMe, Coumadin (warfarin sodium) is often used to treat blood clots. Sudafed (pseudoephedrine hydrochloride) is often used to treat nasal congestion. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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