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Review: Cymbalta and Phentermine

This review analyzes the effectiveness and drug interactions between Cymbalta and Phentermine. It is created by eHealthMe based on reports of 109 people who take the same drugs from FDA and social media, and is updated regularly.

Get connected: join a mobile support group for people who take Cymbalta and Phentermine >>>

What are the drugs

Cymbalta (latest outcomes from 49,191 users) has active ingredients of duloxetine hydrochloride. It is often used in depression.

Phentermine (latest outcomes from 12,965 users) has active ingredients of phentermine hydrochloride. It is often used in obesity.

On Aug, 30, 2014: 109 people who take Cymbalta, Phentermine are studied

Cymbalta, Phentermine outcomes

Drug combinations in study:
- Cymbalta (duloxetine hydrochloride)
- Phentermine (phentermine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Cymbalta is effective20.00%
(1 of 5 people)
(5 of 12 people)
(2 of 6 people)
(3 of 5 people)
(6 of 11 people)
(3 of 3 people)
(1 of 2 people)
Phentermine is effective12.50%
(1 of 8 people)
(5 of 13 people)
(3 of 10 people)
(2 of 6 people)
(1 of 2 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
NauseaDepressionHigh Blood PressureSerotonin SyndromeVertigo PositionalType 2 Diabetes MellitusDepressionArthralgia
Drug IneffectiveArthralgiaHeadacheDizzinessMuscle TwitchingRheumatoid ArthritisHair LossDrug Ineffective
InsomniaAnxietyHair LossFeverShaking PalsyNeuropathy PeripheralWeight Increased
DizzinessOedema PeripheralAdipsiaExhaustion, Fatigue, Lethargy, Tiredness, WearinessLightheadednessSomnolence
IrritabilityDeep Vein ThrombosisDizzinessJaundiceMuscle WeaknessPain
ParaesthesiaNauseaLoss Of LibidoRashDepressionFatigue
NightmareUrinary Tract InfectionNauseaNauseaGeneralised Anxiety DisorderOedema Peripheral
PalpitationsHemiparesisLiver Function Test AbnormalDelusions, MixedDrug Withdrawal Syndrome
Blood Pressure IncreasedVaginal HaemorrhageHigh Blood PressureAmnesia

Drug effectiveness by gender :

Cymbalta is effective50.00%
(20 of 40 people)
(0 of 3 people)
Phentermine is effective29.73%
(11 of 37 people)
(1 of 2 people)

Most common drug interactions by gender * :

Drug IneffectiveOrgasm Abnormal
Weight IncreasedFoot Fracture
Oedema PeripheralFeeling Hot
FatigueCarpal Tunnel Syndrome
PainErectile Dysfunction
Muscle SpasmsIrritability
Drug Withdrawal Syndrome

Drug effectiveness by age :

Cymbalta is effectiven/an/an/a25.00%
(1 of 4 people)
(3 of 16 people)
(11 of 25 people)
(3 of 10 people)
(2 of 2 people)
Phentermine is effectiven/an/an/a33.33%
(1 of 3 people)
(2 of 14 people)
(6 of 23 people)
(2 of 10 people)
(1 of 2 people)

Most common drug interactions by age * :

n/an/an/aArthralgiaType 2 Diabetes MellitusDrug IneffectiveSomnolenceArthralgia
Deep Vein ThrombosisNeuropathy PeripheralNauseaJoint SwellingFibromyalgia
Oedema PeripheralRheumatoid ArthritisWeight IncreasedHyperhidrosisHip Arthroplasty
Pulmonary EmbolismHypertensionAmnesiaOrgasm AbnormalHypertension
YawningType 1 Diabetes MellitusLigament SprainFoot FractureHepatic Enzyme Increased
Diabetic NeuropathyJoint InjuryFeeling HotWeight Decreased
Cerebral Artery ThrombosisPainCarpal Tunnel SyndromeHair Loss
Cerebral InfarctionMeniscus LesionErectile Dysfunction
AstheniaMuscle InjuryRash Generalised
SyncopeImpaired Driving AbilityWound Infection Staphylococcal

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Cymbalta and Phentermine?

Get connected! Join a mobile support group:
- group for people who take Cymbalta and Phentermine
- group for people who take Cymbalta
- group for people who take Phentermine

Comments from related studies:

  • From this study (12 months ago):

  • Since hospitalized for diagnosis of Barett's disease in mid august have lost almost 30 lbs., constantly weak and fatigued when though weighing more was very fit. Now can hardly make it to 7:30 for bed.


  • From this study (12 months ago):

  • Diagnosed with Barett's disease in mid-Augusted. Am 56 years old and was very fit and active prior to illness. Was hospitalized and lost 15 lbs in 4 weeks. Have been exhausted since and unable to perform former physical activity.


  • From this study (3 years ago):

  • I take the Zofran to offset the extreme nausea that the Cymbalta gives me. Zofran is magical.


Can you answer these questions (what is this?):

More questions for: Cymbalta, Phentermine

You may be interested at these reviews (what is this?):

  • Trigeminal neuralgia after use of phentermine
    I am insulin resistant, unable to lose weight w/diet and exercise. Started us of Phentermine for about 6 days and had increasing symptoms of abscess tooth. Went to dentist, was not a tooth, he thought it was a sinus infection. Antibiotics did not work. My PCP gave me more antibiotics. Did not work. ...

  • Which issue has caused my periodontitis, my fibromyalgia or spinal stenosis?
    At the age of 38 yrs old, I was diagnosed with Fibromyalgia and Spinal Stenosis. Obviously I had both of the disease for some years, and was struggling with the pain and symptoms for some time before I finally got checked, went through years being told they didn't find anything, told I had Herniated ...

  • Bpd and insomnia with abilify and cymbalta
    I am currently in recovery from BPD, but still have some traits. I also suffer from depression. I suffer with insomnia also. I have noticed that if I forget to take my meds, I have a higher chance of not sleeping that night.

More reviews for: Cymbalta, Phentermine

Complete drug side effects:

On eHealthMe, Cymbalta (duloxetine hydrochloride) is often used to treat depression. Phentermine (phentermine hydrochloride) is often used to treat weight loss. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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