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Review: Cymbalta and Phentermine

This review analyzes the effectiveness and drug interactions between Cymbalta and Phentermine. It is created by eHealthMe based on reports of 108 people who take the same drugs from FDA and social media, and is updated regularly.

Stay connected: join a mobile support group for people who take Cymbalta and Phentermine >>>

What are the drugs

Cymbalta (latest outcomes from 49,154 users) has active ingredients of duloxetine hydrochloride. It is used in depression.

Phentermine (latest outcomes from 12,944 users) has active ingredients of phentermine hydrochloride. It is used in weight loss.

On Jul, 31, 2014: 108 people who take Cymbalta, Phentermine are studied

Cymbalta, Phentermine outcomes

Drug combinations in study:
- Cymbalta (duloxetine hydrochloride)
- Phentermine (phentermine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Cymbalta is effective20.00%
(1 of 5 people)
(5 of 12 people)
(2 of 6 people)
(3 of 5 people)
(6 of 11 people)
(2 of 2 people)
(1 of 2 people)
Phentermine is effective12.50%
(1 of 8 people)
(5 of 13 people)
(3 of 10 people)
(2 of 6 people)
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
NauseaDepressionHigh Blood PressureSerotonin SyndromeVertigo PositionalType 2 Diabetes MellitusDepressionArthralgia
Drug IneffectiveArthralgiaHeadacheDizzinessMuscle TwitchingRheumatoid ArthritisHair LossDrug Ineffective
InsomniaAnxietyHair LossFeverShaking PalsyNeuropathy PeripheralWeight Increased
DizzinessOedema PeripheralAdipsiaExhaustion, Fatigue, Lethargy, Tiredness, WearinessLightheadednessSomnolence
IrritabilityDeep Vein ThrombosisDizzinessJaundiceMuscle WeaknessPain
ParaesthesiaNauseaLoss Of LibidoRashDepressionFatigue
NightmareUrinary Tract InfectionNauseaNauseaGeneralised Anxiety DisorderOedema Peripheral
PalpitationsHemiparesisLiver Function Test AbnormalDelusions, MixedDrug Withdrawal Syndrome
Blood Pressure IncreasedVaginal HaemorrhageHigh Blood PressureAmnesia

Drug effectiveness by gender :

Cymbalta is effective48.72%
(19 of 39 people)
(0 of 3 people)
Phentermine is effective27.78%
(10 of 36 people)
(1 of 2 people)

Most common drug interactions by gender * :

Drug IneffectiveOrgasm Abnormal
Weight IncreasedFoot Fracture
Oedema PeripheralFeeling Hot
FatigueCarpal Tunnel Syndrome
PainErectile Dysfunction
Muscle SpasmsAnxiety

Drug effectiveness by age :

Cymbalta is effectiven/an/an/a25.00%
(1 of 4 people)
(3 of 16 people)
(11 of 25 people)
(2 of 9 people)
(2 of 2 people)
Phentermine is effectiven/an/an/a33.33%
(1 of 3 people)
(2 of 14 people)
(6 of 23 people)
(1 of 9 people)
(1 of 2 people)

Most common drug interactions by age * :

n/an/an/aArthralgiaType 2 Diabetes MellitusDrug IneffectiveJoint SwellingArthralgia
Deep Vein ThrombosisNeuropathy PeripheralNauseaSomnolenceFibromyalgia
Oedema PeripheralRheumatoid ArthritisWeight IncreasedFoot FractureHip Arthroplasty
Pulmonary EmbolismHypertensionAmnesiaNauseaHypertension
YawningType 1 Diabetes MellitusLigament SprainHyperhidrosisHepatic Enzyme Increased
Diabetic NeuropathyJoint InjuryOrgasm AbnormalWeight Decreased
Cerebral Artery ThrombosisPainWound Infection StaphylococcalHair Loss
Cerebral InfarctionMeniscus LesionFeeling Hot
AstheniaMuscle InjuryErectile Dysfunction
SyncopeImpaired Driving AbilityRash Generalised

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Get connected! Join a mobile support group to help out with your experience or learn from others anytime and anywhere:
- group for people who take Cymbalta and Phentermine
- group for people who take Cymbalta
- group for people who take Phentermine

Comments from related studies:

  • From this study (10 months ago):

  • Since hospitalized for diagnosis of Barett's disease in mid august have lost almost 30 lbs., constantly weak and fatigued when though weighing more was very fit. Now can hardly make it to 7:30 for bed.


  • From this study (10 months ago):

  • Diagnosed with Barett's disease in mid-Augusted. Am 56 years old and was very fit and active prior to illness. Was hospitalized and lost 15 lbs in 4 weeks. Have been exhausted since and unable to perform former physical activity.


  • From this study (3 years ago):

  • I take the Zofran to offset the extreme nausea that the Cymbalta gives me. Zofran is magical.


Can you answer these questions (what is this?):

More questions for: Cymbalta, Phentermine

You may be interested at these reviews (what is this?):

  • Bpd and insomnia with abilify and cymbalta
    I am currently in recovery from BPD, but still have some traits. I also suffer from depression. I suffer with insomnia also. I have noticed that if I forget to take my meds, I have a higher chance of not sleeping that night.

  • Latuda stoped hypoglcymia
    I have hypoglycemia and have had to be carefull of my sugar intake. Started taking Latuda and now i can eat sugar like most people do

  • Hiccups with cymbalta
    I have been on the drug Cymbalta for almost four days. Within these four days I have had extreme hiccups!! Sometimes just a random loud, out of no where hiccup. And others consisting over an hour long. This is very irritating.. I never thought a medicine. Would do such a thing! Does anyone know what ...

More reviews for: Cymbalta, Phentermine

Complete drug side effects:

On eHealthMe, Cymbalta (duloxetine hydrochloride) is often used to treat depression. Phentermine (phentermine hydrochloride) is often used to treat weight loss. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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