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Review: taking Cymbalta and Zoloft together

Summary: drug interactions are reported among people who take Cymbalta and Zoloft together.

This review analyzes the effectiveness and drug interactions between Cymbalta and Zoloft. It is created by eHealthMe based on reports of 1,324 people who take the same drugs from FDA and social media, and is updated regularly.

 

 

 

 

You are not alone: join a mobile support group for people who take Cymbalta and Zoloft >>>

What are the drugs

Cymbalta has active ingredients of duloxetine hydrochloride. It is often used in depression. (latest outcomes from 49,362 Cymbalta users)

Zoloft has active ingredients of sertraline hydrochloride. It is often used in depression. (latest outcomes from 78,365 Zoloft users)

On Feb, 1, 2015: 1,324 people who take Cymbalta, Zoloft are studied

Cymbalta, Zoloft outcomes

Drug combinations in study:
- Cymbalta (duloxetine hydrochloride)
- Zoloft (sertraline hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Cymbalta is effective33.33%
(3 of 9 people)
21.43%
(3 of 14 people)
0.00%
(0 of 7 people)
16.67%
(1 of 6 people)
80.00%
(4 of 5 people)
0.00%
(0 of 1 people)
n/a0.00%
(0 of 1 people)
Zoloft is effective28.57%
(2 of 7 people)
25.00%
(2 of 8 people)
0.00%
(0 of 3 people)
11.11%
(1 of 9 people)
28.57%
(2 of 7 people)
33.33%
(1 of 3 people)
0.00%
(0 of 4 people)
0.00%
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
NauseaType 2 Diabetes MellitusStress FractureAngerPainChest PainDrug IneffectivePain
PainDepressionOsteopeniaFeeling AbnormalDepressionGastrooesophageal Reflux DiseaseFatigueAnxiety
DiarrhoeaSuicidal IdeationHip FractureWeight IncreasedPancreatitisAnxietySomnolenceDepression
PruritusAnxietyRib FractureDizzinessAnxietyDepressionKnee ArthroplastyNausea
HypertensionConfusional StatePainLoss Of LibidoRoad Traffic AccidentPainSuicidal BehaviourHeadache
FallBradyphreniaBone Density DecreasedContusionHallucinationPulmonary EmbolismDepressionFall
HypophagiaBradykinesiaSuicidal IdeationFearSleep Apnoea SyndromeInjurySuicidal IdeationDrug Ineffective
AnxietyHallucinationAnxietyBalance DisorderSuicide AttemptArthralgiaOverdoseType 2 Diabetes Mellitus
Abdominal Pain UpperHyperhidrosisDepressed MoodCerebral HaemorrhageTardive DyskinesiaAcute Myocardial InfarctionArthropathyFatigue
Abdominal PainAlanine Aminotransferase IncreasedType 2 Diabetes MellitusOesophageal UlcerWeight DecreasedEmotional DistressSurgeryBack Pain

Drug effectiveness by gender :

FemaleMale
Cymbalta is effective28.57%
(10 of 35 people)
14.29%
(1 of 7 people)
Zoloft is effective20.00%
(7 of 35 people)
14.29%
(1 of 7 people)

Most common drug interactions by gender * :

FemaleMale
AnxietyPain
PainHeadache
DepressionAnxiety
NauseaDepression
FallFatigue
HeadacheWeight Decreased
ArthralgiaBack Pain
Type 2 Diabetes MellitusType 2 Diabetes Mellitus
Drug IneffectiveVomiting
DyspnoeaDrug Ineffective

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Cymbalta is effectiven/an/a0.00%
(0 of 2 people)
0.00%
(0 of 4 people)
6.78%
(4 of 59 people)
10.00%
(2 of 20 people)
22.73%
(5 of 22 people)
0.00%
(0 of 2 people)
Zoloft is effectiven/an/a0.00%
(0 of 2 people)
50.00%
(2 of 4 people)
2.82%
(2 of 71 people)
14.29%
(2 of 14 people)
4.35%
(1 of 23 people)
50.00%
(1 of 2 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Umbilical Cord Around NeckPremature BabyCholecystitis ChronicCholecystitis ChronicType 2 Diabetes MellitusPainAnxietyFall
Neonatal DisorderLow Birth Weight BabyPainNauseaDiabetes MellitusDepressionPainPain
Drug Exposure Via Breast MilkFoetal Exposure During PregnancyGallbladder DisorderAbdominal PainBlood Cholesterol IncreasedType 2 Diabetes MellitusNauseaAnxiety
Cyanosis NeonatalAnxietyDiarrhoeaDiabetic NeuropathyAnxietyPyrexiaPain In Extremity
Body Temperature FluctuationSphincter Of Oddi DysfunctionAbdominal Pain UpperHyperlipidaemiaHeadacheOsteonecrosis Of JawAnaemia
Neonatal HypotensionPancreatitisCholelithiasisAnxietyDrug IneffectiveFallBack Pain
Ischaemic StrokeDrug DependenceBiliary DyskinesiaPainDyspnoeaDepressionDizziness
DysphagiaNauseaHypersensitivityHyperglycaemiaFallHeadacheHypotension
Drug Exposure During PregnancyDisturbance In AttentionGallbladder DisorderDiabetes Mellitus Inadequate ControlMuscle SpasmsPain In JawFatigue
Convulsion NeonatalCondition AggravatedOcular HyperaemiaObesityBack PainFatigueDrug Ineffective

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of Cymbalta and Zoloft on

Do you take Cymbalta and Zoloft?

You are not alone! Join a related mobile support group:
- support group for people who take Cymbalta and Zoloft
- support group for people who take Cymbalta
- support group for people who take Zoloft

Recent conversations of related support groups:

  • Support group for people who take Cymbalta
    Now found out I have incompetent vein in leg which may be part of the problem had cystocopy and found cysts in kidney, then developed hypertension but no one will diagnose the pain. Now decided it is the same as diabetic neuropathy but as gp and consultant point out I am a long way from being diabetic with perfect blood glucose so thinks it's just guessing and hope
  • Support group for people who take Zoloft
    That's the truth! :( Sorry there isn't an easy fix.

Can you answer these questions (Ask a question):

  • Is bed wetting part of having syringomyelia
    i also use panadol osteo, mintec, apo-meloxicam. i have wetting the bed is was just now and then but it has started to become more frequent now, does any one else had this happen.
  • Ok to take losartan and zoloft together before bed? (2 answers)
    I've been on Losartan for a year without any problem. Six weeks ago I started on 25mg of Zoloft for general anxiety. All of a sudden during cardio exercise I feel lightheadedness and a feeling like I could pass out! I stop for a moment and then I feel ok. Is this normal? I thought I'd be getting more used to it after 6 weeks, but this is something new so I figured that it is now in my body and fatigue is normal. Or perhaps taking bp meds and Zoloft might be the cause.
  • Does the thymus affect dysthymia
    joy of living is imparted to the child by the bonding process. the thymus helps in developing antibodies and setting up the immune system and its function lessens through puberty until it effectively atrophies at maturity. my thesis is that a lack of bonding interferes with the action of the thymus leading to dysthymia (Greek for bad state of mind), elsewhere described as 'chronic discontent
  • Can cymbalta cause dementia?
    I have been on Cymbalta for 5 years and was wondering if it has caused my Alzheimer's or dementia?
  • Does anyone taking isosorbide or ranexa have severe nightmares?
    I have horribly, terrifying nightmares, every night. They are all variations on a theme of terror.

More questions for: Cymbalta, Zoloft

You may be interested at these reviews (Write a review):

  • Took buspirone once and got a blister
    Took Buspirone 5mg once and a few minutes later felt a bubble on my lip. The next morning I check and sure enough it's a blister on my top lip. Called a nurse and she said I had an allergic reaction.
  • Fluoxetine with hypnagogic hallucinations
    Was taking fluoxetine until recently for a depressive episode (suffered from depression pretty much my whole life). Strange hypnagogic hallucinations and bizarre thoughts, sometimes coupled with feeling faint. Also strong feelings of numbness for the first two weeks or so, headaches and dry mouth. Strangely only on 20mg...This is my second time on fluoxetine and the experience has been totally different (last time it seemed to make me act callously and superficially towards people, and to be generally irresponsible, going out, avoiding work etc.).

    Doctor had now changed me over to sertraline, been on it for 3 days and ok so far apart from minor headaches.
  • Terrible excessive sweating from hydrochlorothiazide
    I guess I fit the profile of who gets excessive sweating from HCTZ. I am a 65 year old female and suffered from excessive sweating for two years. With just very little exertion, I would pour sweat from the top of my head. It would run into my face and all over my hair. My hair would be ringing wet. I had heavy perspiration in the groin area and down my back also. I had to change clothing 2-3 times a day and wash up or shower that many times also. The doctor tried changing my Cymbalta and put me on Wellbutrin instead. It did absolutely no good. I went off the wellbutrin and back onto the Cymbalta. I did some research and saw that HCTZ could cause excessive sweating. Both my doctor and my pharmacist said that they had never heard of that. I went off the HCTZ, and my sweating stopped almost immediately. My doctor and my pharmacist were very surprised. I'm one of those people who frequently have different reactions to drugs than are typical. If you're having excessive perspiration and are on HCTZ, try going off of it. It just may be the culprit!
  • The zoloft/vyvanse concoction ruined my life.
    I started taking these drugs about two months ago. I am diagnosed ADHD by a psychiatrist. I received these medications from a doctor whom I know and is married to a friend my wife. She, the doctor, gave them to me from her personal medications in a plastic baggy. I was given loose instructions for taking these on a piece of paper. I was never given the paperwork with warning signs. 10 days after starting these medications, I attacked my wife and am now separated. I am barred from seeing her and my daughter by means of a Victims Protective Order. I am a normally nonviolent person. Most who know me call me a peacemaker...a pacifist. I am still horrified by the events of that night. 15 seconds changed my life forever. I hope and pray my story helps others. Don't be naïve, as I was, when given medications. Ask questions.
  • Cymbalta side effects
    Starting Cymbalta, side effects were dizzy,felt drugged. Helped with Arthritis pain. About six weeks after i started i developed rectal bleeding.Doctor had me stop Cymbalta and use Tramadol as needed for withdrawal.

More reviews for: Cymbalta, Zoloft

Comments from related studies:

  • From this study (3 months ago):

  • doc moc on Apr, 25, 2013:

    BREAK down FOOL!

    Reply

    Rhs on Oct, 13, 2012:

    Get your medical records
    and consult w/your doctor

    Reply

    trust1983 on Dec, 3, 2012:

    Is it true in the states that a psych doc can up and just leave and refuse to treat you because you tried to kill yourself, especially if you didn't have a contact for life with you r doc?

    Reply

Post a new comment    OR    Read more comments

Complete drug side effects:

On eHealthMe, Cymbalta (duloxetine hydrochloride) is often used to treat depression. Zoloft (sertraline hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

   

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