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Review: Cymbalta and Zoloft





Summary: drug interactions are reported among people who take Cymbalta and Zoloft together.

This review analyzes the effectiveness and drug interactions between Cymbalta and Zoloft. It is created by eHealthMe based on reports of 1,322 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Cymbalta and Zoloft >>>

What are the drugs

Cymbalta has active ingredients of duloxetine hydrochloride. It is often used in depression. (latest outcomes from Cymbalta 49,275 users)

Zoloft has active ingredients of sertraline hydrochloride. It is often used in depression. (latest outcomes from Zoloft 78,283 users)

On Nov, 26, 2014: 1,322 people who take Cymbalta, Zoloft are studied

Cymbalta, Zoloft outcomes

Drug combinations in study:
- Cymbalta (duloxetine hydrochloride)
- Zoloft (sertraline hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Cymbalta is effective33.33%
(3 of 9 people)
23.08%
(3 of 13 people)
0.00%
(0 of 7 people)
16.67%
(1 of 6 people)
100.00%
(4 of 4 people)
0.00%
(0 of 1 people)
n/a0.00%
(0 of 1 people)
Zoloft is effective28.57%
(2 of 7 people)
28.57%
(2 of 7 people)
0.00%
(0 of 3 people)
12.50%
(1 of 8 people)
28.57%
(2 of 7 people)
33.33%
(1 of 3 people)
0.00%
(0 of 4 people)
0.00%
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
NauseaType 2 Diabetes MellitusStress FractureAngerPainChest PainDrug IneffectivePain
PainDepressionOsteopeniaFeeling AbnormalDepressionGastrooesophageal Reflux DiseaseFatigueAnxiety
DiarrhoeaSuicidal IdeationHip FractureWeight IncreasedPancreatitisAnxietySomnolenceDepression
PruritusAnxietyRib FractureDizzinessAnxietyDepressionKnee ArthroplastyNausea
HypertensionConfusional StatePainLoss Of LibidoRoad Traffic AccidentPainSuicidal BehaviourHeadache
FallBradyphreniaBone Density DecreasedContusionSuicide AttemptPulmonary EmbolismDepressionFall
HypophagiaBradykinesiaSuicidal IdeationFearSleep Apnoea SyndromeInjurySuicidal IdeationDrug Ineffective
AnxietyHyperhidrosisAnxietyBalance DisorderHallucinationArthralgiaOverdoseType 2 Diabetes Mellitus
Abdominal Pain UpperHallucinationDepressed MoodCerebral HaemorrhageConvulsionAcute Myocardial InfarctionArthropathyFatigue
Abdominal PainPainType 2 Diabetes MellitusOesophageal UlcerWeight DecreasedEmotional DistressSurgeryBack Pain

Drug effectiveness by gender :

FemaleMale
Cymbalta is effective29.41%
(10 of 34 people)
16.67%
(1 of 6 people)
Zoloft is effective20.59%
(7 of 34 people)
16.67%
(1 of 6 people)

Most common drug interactions by gender * :

FemaleMale
AnxietyPain
PainHeadache
DepressionAnxiety
NauseaDepression
FallFatigue
Type 2 Diabetes MellitusWeight Decreased
ArthralgiaBack Pain
HeadacheType 2 Diabetes Mellitus
Drug IneffectiveVomiting
DyspnoeaDrug Ineffective

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Cymbalta is effectiven/an/a0.00%
(0 of 2 people)
0.00%
(0 of 4 people)
6.78%
(4 of 59 people)
10.53%
(2 of 19 people)
29.41%
(5 of 17 people)
0.00%
(0 of 2 people)
Zoloft is effectiven/an/a0.00%
(0 of 2 people)
50.00%
(2 of 4 people)
2.82%
(2 of 71 people)
15.38%
(2 of 13 people)
5.56%
(1 of 18 people)
50.00%
(1 of 2 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Umbilical Cord Around NeckPremature BabyCholecystitis ChronicCholecystitis ChronicType 2 Diabetes MellitusPainAnxietyFall
Neonatal DisorderLow Birth Weight BabyPainNauseaDiabetes MellitusDepressionPainPain
Drug Exposure Via Breast MilkFoetal Exposure During PregnancyGallbladder DisorderAbdominal PainBlood Cholesterol IncreasedType 2 Diabetes MellitusNauseaAnxiety
Cyanosis NeonatalAnxietyDiarrhoeaDiabetic NeuropathyAnxietyPyrexiaPain In Extremity
Body Temperature FluctuationSphincter Of Oddi DysfunctionAbdominal Pain UpperHyperlipidaemiaHeadacheOsteonecrosis Of JawAnaemia
Neonatal HypotensionPancreatitisCholelithiasisAnxietyDrug IneffectiveFallBack Pain
Ischaemic StrokeDrug DependenceBiliary DyskinesiaPainDyspnoeaHeadacheDizziness
DysphagiaNauseaHypersensitivityHyperglycaemiaFallFatigueHypotension
Drug Exposure During PregnancyDisturbance In AttentionGallbladder DisorderDiabetes Mellitus Inadequate ControlMuscle SpasmsDepressionFatigue
Convulsion NeonatalCondition AggravatedOcular HyperaemiaObesityArthralgiaPain In JawDrug Ineffective

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Cymbalta and Zoloft?

You are not alone! Join a related mobile support group:
- support group for people who take Cymbalta and Zoloft
- support group for people who take Cymbalta
- support group for people who take Zoloft

Recent conversations of related support groups:

  • Support group for people who take Cymbalta
    Now found out I have incompetent vein in leg which may be part of the problem had cystocopy and found cysts in kidney, then developed hypertension but no one will diagnose the pain. Now decided it is the same as diabetic neuropathy but as gp and consultant point out I am a long way from being diabetic with perfect blood glucose so thinks it's just guessing and hope
  • Support group for people who take Zoloft
    That's the truth! :( Sorry there isn't an easy fix.

Can you answer these questions (Ask a question):

More questions for: Cymbalta, Zoloft

You may be interested at these reviews (Write a review):

  • Terrible excessive sweating from hydrochlorothiazide
    I guess I fit the profile of who gets excessive sweating from HCTZ. I am a 65 year old female and suffered from excessive sweating for two years. With just very little exertion, I would pour sweat from the top of my head. It would run into my face and all over my hair. My hair would be ringing wet. I had heavy perspiration in the groin area and down my back also. I had to change clothing 2-3 times a day and wash up or shower that many times also. The doctor tried changing my Cymbalta and put me on Wellbutrin instead. It did absolutely no good. I went off the wellbutrin and back onto the Cymbalta. I did some research and saw that HCTZ could cause excessive sweating. Both my doctor and my pharmacist said that they had never heard of that. I went off the HCTZ, and my sweating stopped almost immediately. My doctor and my pharmacist were very surprised. I'm one of those people who frequently have different reactions to drugs than are typical. If you're having excessive perspiration and are on HCTZ, try going off of it. It just may be the culprit!
  • The zoloft/vyvanse concoction ruined my life.
    I started taking these drugs about two months ago. I am diagnosed ADHD by a psychiatrist. I received these medications from a doctor whom I know and is married to a friend my wife. She, the doctor, gave them to me from her personal medications in a plastic baggy. I was given loose instructions for taking these on a piece of paper. I was never given the paperwork with warning signs. 10 days after starting these medications, I attacked my wife and am now separated. I am barred from seeing her and my daughter by means of a Victims Protective Order. I am a normally nonviolent person. Most who know me call me a peacemaker...a pacifist. I am still horrified by the events of that night. 15 seconds changed my life forever. I hope and pray my story helps others. Don't be naïve, as I was, when given medications. Ask questions.
  • Cymbalta side effects
    Starting Cymbalta, side effects were dizzy,felt drugged. Helped with Arthritis pain. About six weeks after i started i developed rectal bleeding.Doctor had me stop Cymbalta and use Tramadol as needed for withdrawal.
  • Loss of menstruation
    Hi
    I stopped using setralin 50 µg in August 2014. (I have been taken it in 1 year for my PMS). After stopping taking the pills my period become very short in september and then desappeard. I got a funcional cyste (about 30 mm) and after 10-days treatment with progesterone I got my period in the end of oktober. Two weeks afterwards I got a spare bleeding and my gyn thought that it my be an ovulation bleeding. Anyhow I have not got my period yet. The samples taken in oktober showed low FSH and heigt E2. The doctor explained that it is posible that stopping setralin could cause this hormonal imbalance. I must say that my periods were not so regular for very long time like during that year with setralin but I had other side effects like problem with concentartion, nussea etc.
    For many years ago I was on Zoloft but I had not experienced the same problem. When I started the treatment this time they did not want to give me zoloft (because of the price). I had no choice but i experienced many symptoms from different generica of Setralin. I will meet my doctor om Monday again.
  • Cardio version caused fingernail abnormalities
    Right hip fracture. When prepping for surgery AFIB was found. Surgery was cancelled and they attempted to get AFIB under control. Finally, cardioversion was performed. When my nails started to grow out they all had two horizontal lines that cause the nail to break when it grows out to that point.

More reviews for: Cymbalta, Zoloft

Comments from related studies:

  • From this study (2 months ago):

  • doc moc on Apr, 25, 2013:

    BREAK down FOOL!

    Reply

    Rhs on Oct, 13, 2012:

    Get your medical records
    and consult w/your doctor

    Reply

    trust1983 on Dec, 3, 2012:

    Is it true in the states that a psych doc can up and just leave and refuse to treat you because you tried to kill yourself, especially if you didn't have a contact for life with you r doc?

    Reply

Post a new comment    OR    Read more comments

Complete drug side effects:

On eHealthMe, Cymbalta (duloxetine hydrochloride) is often used to treat depression. Zoloft (sertraline hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

   

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