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Review: taking Depakote and Prazosin together

Summary: drug interactions are reported among people who take Depakote and Prazosin together.

This review analyzes the effectiveness and drug interactions between Depakote and Prazosin. It is created by eHealthMe based on reports of 40 people who take the same drugs from FDA and social media, and is updated regularly.





You are not alone: join a mobile support group for people who take Depakote and Prazosin >>>

What are the drugs

Depakote has active ingredients of divalproex sodium. It is often used in bipolar disorder. (latest outcomes from 30,950 Depakote users)

Prazosin hydrochloride has active ingredients of prazosin hydrochloride. It is often used in post-traumatic stress disorder. (latest outcomes from 389 Prazosin hydrochloride users)

On Feb, 4, 2015: 40 people who take Depakote, Prazosin Hydrochloride are studied

Depakote, Prazosin Hydrochloride outcomes

Drug combinations in study:
- Depakote (divalproex sodium)
- Prazosin Hydrochloride (prazosin hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Depakote is effectiven/a0.00%
(0 of 1 people)
(0 of 1 people)
Prazosin Hydrochloride is effectiven/a0.00%
(0 of 1 people)
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
VomitingFeeling AbnormalHypomagnesemian/an/an/aHypomagnesemiaGranulocytopenia
Urinary IncontinenceDrug IneffectiveConfusional State
CheilitisDepressionBarrett's Oesophagus
Tongue DisorderWeight IncreasedDepression
StomatitisConvulsions NosAbnormal Dreams
Pharyngeal OedemaFallWithdrawal Syndrome
Musculoskeletal StiffnessThrombocytopeniaCold Sweat
Monocyte Count IncreasedCerebral HaemorrhageHyperhidrosis
Drug Level DecreasedVomiting

Drug effectiveness by gender :

Depakote is effectiven/a0.00%
(0 of 2 people)
Prazosin Hydrochloride is effectiven/a0.00%
(0 of 2 people)

Most common drug interactions by gender * :

Confusional StateBlood Glucose Increased
Cold SweatGranulocytopenia
Barrett's OesophagusHaematocrit Decreased
Abnormal DreamsHaemoglobin Decreased
Withdrawal SyndromeBlood Triglycerides Increased
TremorPharyngeal Oedema
Infusion Site SwellingBlood Cholesterol Increased

Drug effectiveness by age :

Depakote is effectiven/an/an/an/a0.00%
(0 of 2 people)
Prazosin Hydrochloride is effectiven/an/an/an/a0.00%
(0 of 2 people)

Most common drug interactions by age * :

n/an/aStrabismusSinus TachycardiaNauseaConfusional StateGranulocytopeniaDepression
Musculoskeletal StiffnessVertigoOesophageal RefluxBarrett's OesophagusBlood Glucose IncreasedInsomnia
Urinary IncontinenceHypertensionPruritusAbnormal DreamsBlood Cholesterol IncreasedFlatulence
VomitingGranulocytopeniaVomiting NosHyperhidrosisHaematocrit DecreasedFatigue
GranulocytopeniaLeukopeniaLiver Function Tests Nos AbnormalCold SweatHaemoglobin DecreasedNausea
Monocyte Count IncreasedJaundice NosTremorInfusion Site ErythemaNightmare
Impulsive BehaviourAbdominal Pain UpperWithdrawal SyndromeInfusion Site SwellingTobacco User
Drug Level DecreasedBlood Bilirubin IncreasedFeeling AbnormalColitisSpeech Disorder
Confusional StateFatigueDepressionBlood Triglycerides IncreasedPain
DyskinesiaHypomagnesemiaDrug IneffectiveDementia Alzheimer's TypeDyspnoea

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Depakote and Prazosin?

You are not alone! Join a related mobile support group:
- support group for people who take Depakote and Prazosin
- support group for people who take Depakote
- support group for people who take Prazosin Hydrochloride

Can you answer these questions (Ask a question):

More questions for: Depakote, Prazosin Hydrochloride

You may be interested at these reviews (Write a review):

  • Seizure patient was on depakote for 16 years now on keppra 1500 mg.
    I am 28 years old and been off depakote for 5 months. I started keppra to control my seizure disorder, which works great. But for the past year I have developed osteoarthritis in my thoracic, si joints, and lumbar. I get alot of muscle hypersensitivity and pain. Can any of this be due to long term effects of seizure meds?
  • Depakote er affected by grapefruit
    I have taken Depakote ER for since 2005 for epilepsy. Once stabilized many years ago seizures and auras have not been bothering me. Until I recently ate three grapefruits over three days. After a few days, when the grapefruit cleared my system, the seizures and auras ceased. Therefore, grapefruit does affect how Depakote ER acts on your system.

More reviews for: Depakote, Prazosin Hydrochloride

Complete drug side effects:

On eHealthMe, Depakote (divalproex sodium) is often used to treat bipolar disorder. Prazosin Hydrochloride (prazosin hydrochloride) is often used to treat post-traumatic stress disorder. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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