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Review: taking Depakote Er and Keppra together

Summary: drug interactions are reported among people who take Depakote Er and Keppra together.

This review analyzes the effectiveness and drug interactions between Depakote Er and Keppra. It is created by eHealthMe based on reports of 860 people who take the same drugs from FDA and social media, and is updated regularly.

 

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On Mar, 30, 2015: 860 people who take Depakote Er, Keppra are studied

Depakote Er, Keppra outcomes

Drug combinations in study:
- Depakote Er (divalproex sodium)
- Keppra (levetiracetam)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Depakote Er is effective100.00%
(1 of 1 people)
25.00%
(1 of 4 people)
0.00%
(0 of 4 people)
50.00%
(3 of 6 people)
14.29%
(1 of 7 people)
87.50%
(7 of 8 people)
66.67%
(6 of 9 people)
0.00%
(0 of 1 people)
Keppra is effective50.00%
(1 of 2 people)
40.00%
(2 of 5 people)
40.00%
(2 of 5 people)
0.00%
(0 of 6 people)
36.36%
(4 of 11 people)
83.33%
(5 of 6 people)
50.00%
(1 of 2 people)
n/a

Drug effectiveness by gender :

FemaleMale
Depakote Er is effective31.25%
(5 of 16 people)
60.87%
(14 of 23 people)
Keppra is effective33.33%
(5 of 15 people)
45.45%
(10 of 22 people)

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Depakote Er is effectiven/a50.00%
(3 of 6 people)
30.00%
(3 of 10 people)
36.84%
(7 of 19 people)
30.00%
(3 of 10 people)
12.50%
(2 of 16 people)
33.33%
(1 of 3 people)
0.00%
(0 of 3 people)
Keppra is effectiven/a50.00%
(2 of 4 people)
10.00%
(1 of 10 people)
29.41%
(5 of 17 people)
20.00%
(2 of 10 people)
25.00%
(4 of 16 people)
33.33%
(1 of 3 people)
0.00%
(0 of 3 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Abnormal BehaviourConvulsionAstheniaSedationConvulsionDiabetes MellitusMemory ImpairmentConvulsion
ConvulsionDrug IneffectiveWeight DecreasedSomnolenceDizzinessDiabetic KetoacidosisHypoglycaemiaSomnolence
Stevens-johnson SyndromeFallAmnesiaEpilepsyGait DisturbanceLeft Ventricular FailureAbnormal Loss Of WeightDizziness
PyrexiaPyrexiaAtaxiaAbnormal BehaviourAstheniaMalaiseSomnolenceTremor
RashConfusional StateConfusional StateDrowningGrand Mal ConvulsionCoronary Artery DiseaseDecreased AppetiteGrand Mal Convulsion
Memory ImpairmentDrug HypersensitivityAppetite DisorderAutismTremorConvulsionVitamin C DeficiencyHeadache
TremorLethargyAbnormal BehaviourSudden Unexplained Death In EpilepsyDrug IneffectiveArteriosclerosis Coronary ArteryAmnesiaDrug Ineffective
Cytolytic HepatitisTremorColitis UlcerativeHypoglycaemiaCognitive DisorderCardiomegalyAbnormal DreamsFall
FatigueSomnolenceComplex Partial SeizuresHyperhidrosisIll-defined DisorderCardiomyopathyAnxietyPneumonia
Hallucination, AuditoryCerebral Arteriovenous Malformation HaemorrhagicDiarrhoea NosSocial PhobiaAmnesiaType 1 Diabetes MellitusAutismMental Status Changes

Most common drug interactions by gender * :

FemaleMale
ConvulsionConvulsion
TremorSomnolence
Mental Status ChangesDrug Ineffective
DizzinessAggression
HeadacheSedation
SomnolenceGrand Mal Convulsion
PneumoniaAbnormal Behaviour
AlopeciaPyrexia
Back PainWeight Increased
MalaiseThrombocytopenia

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Stevens-johnson SyndromeConvulsionConvulsionConvulsionConvulsionConvulsionConvulsionConvulsion
Pneumonia AspirationAggressionSedationAggressionFallMental Status ChangesDizzinessConfusional State
HypersomniaHallucination, AuditoryGrand Mal ConvulsionGranulocytopeniaThrombocytopeniaSomnolenceDrug IneffectiveTremor
Drug Exposure During PregnancyEnuresisWeight DecreasedAngerAnaemia NosBack PainPneumoniaSomnolence
Convulsion NeonatalAbnormal BehaviourAbnormal BehaviourBone Marrow Depression NosSomnolenceAphasiaAstheniaFatigue
Condition AggravatedDizzinessHeadacheUnresponsive To StimuliMultiple Sclerosis RelapseTremorDeath
AngerSomnolenceInjuryDrug IneffectiveProgressive Multifocal LeukoencephalopathyAtelectasisPneumonia
Insulin C-peptide DecreasedRhinorrhoeaPregnancy NosGrand Mal ConvulsionImmune Reconstitution SyndromeTachycardiaCerebrovascular Accident
SomnolenceFallSomnolenceRhabdomyolysisAtaxiaHypotensionFall
Abnormal Behaviour NosHypertensionSuicidal IdeationAnxietyNauseaDysstasiaUrinary Tract Infection

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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- support group for people who take Depakote Er
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Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Depakote Er (divalproex sodium) is often used to treat bipolar disorder. Keppra (levetiracetam) is often used to treat epilepsy. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

   

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