Review: Depakote Er and Keppra drug interactions
This review analyzes the interactions between Depakote Er and Keppra. It is created by eHealthMe based on 820 people who have drug interactions while taking the drugs. The review uses reports from FDA and social media, and is updated regularly.
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What are the drugs
Depakote er (latest outcomes from 3,422 users) has active ingredients of divalproex sodium. It is often used in bipolar disorder.
Keppra (latest outcomes from 21,097 users) has active ingredients of levetiracetam. It is often used in epilepsy.
On Mar, 8, 2014: 820 people who reported to have interactions when taking Depakote Er, Keppra are studied
Drug combinations in study:
- Depakote Er (divalproex sodium)
- Keppra (levetiracetam)
Most common interactions experienced by people in the use of Depakote Er, Keppra:(click on each outcome to view in-depth analysis, incl. how people recovered)
|Interaction||Number of reports|
|Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)||233|
|Somnolence (a state of near-sleep, a strong desire for sleep)||137|
|Grand Mal Convulsion (a type of generalized seizure that affects the entire brain)||49|
|Headache (pain in head)||47|
|Tremor (trembling or shaking movements in one or more parts of your body)||47|
Most common interactions experienced by people in long term use of Depakote Er, Keppra:(click on each outcome to view in-depth analysis, incl. how people recovered)
|Interaction||Number of reports|
|Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)||36|
|Somnolence (a state of near-sleep, a strong desire for sleep)||20|
|Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)||19|
|Hypoglycaemia (deficiency of glucose in the bloodstream)||18|
|Vitamin C Deficiency (a disease caused by deficiency of vitamin c, characterized by spongy and bleeding gums, bleeding under the skin, and extreme weakness)||16|
|Abnormal Loss Of Weight||9|
How effective are the drugs:
|not at all||somewhat||moderate||high||very high|
Top conditions involved for these people * :
- Glioblastoma multiforme
- Grand mal convulsion
- Multiple sclerosis
Top co-used drugs for these people * :
* Approximation only. Some reports may have incomplete information.
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Complete drug side effects:
On eHealthMe, Depakote Er (divalproex sodium) is often used to treat bipolar disorder. Keppra (levetiracetam) is often used to treat epilepsy. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.
What is the drug used for and how effective is it:
- Depakote er is used in:
- Keppra is used in:
Other drugs that are used to treat the same conditions:
- Depakote er alternatives:
- Keppra alternatives:
Comments from related studies:
From this study (3 months ago):
From this study (5 months ago):
From this study (10 months ago):
Took phenobarbital from eight years old to about 22 years old. Took Mysoline from 18 to about 22 years old. Took Dilantin from 12 years old to about 32 years old. Took Depakote only from 32 to 51 years old. Took Depakote and Keppra from 51 years old to present.
he has cerebro pausy can, t talk
Even though I did M.tech in computer science, but never tried to attend job interviews because of these fears for the last 4 years.
Nikkie on May, 31, 2013:
If this doesn't work for you, you should try driclor! I was the same way, I couldn't talk to anyone without my hands dripping (not exaggerating). Driclor is a roll on antiperspirant that has a higher strength of [20%] aluminum chloride hexahydrate. I had to order it online from England, for they do not sell it in the U.S.
Can you answer these questions (what is this?):
- By Ralshell: Has anyone have restless syndrom after taking keppra
I was diagnosed with restless leg syndrome after taking keppra. My condition is serve, luckily I was in the hospital when I had my episode. I was on camera for observation of partial seizure when this happened on my second day in the hospital. Has one had a severely bad episode. I became hysterical ...
- By always kept private: Should you take zoloft with keppra and lamictal
Should I take Zoloft with Keppra and Lamictal? I sometimes feel like I am going to have seizure and this became more prevalent when I began taking Zoloft
- By mah: How do i control my appetite?
currently taking zoloft 15 mg once a day, depacote 500 mg twice a day and abilify 10 mg once a day. having a hard time getting out of bed due to depression. have no appetite when for the first few hours after I wake up, but in the evening all I want to do is eat. what can help to control my cravings ...
You may be interested at these reviews (what is this?):
- By LauraInArizona: Depakote er affected by grapefruit
I have taken Depakote ER for since 2005 for epilepsy. Once stabilized many years ago seizures and auras have not been bothering me. Until I recently ate three grapefruits over three days. After a few days, when the grapefruit cleared my system, the seizures and auras ceased. Therefore, grapefrui ...
- By poetbjc: Health issues and struggles
I have numerous health issues. Some I've lived with not realizing they were there. Others are caused by meds I've taken in the past or am still using now. Lupus is the most recent and biggest trouble I have right now. It is caused by the one drug that finally gave me control of my seizures Some o ...
- By Chelette: Understanding and living with cancer
After having one treatment of Gemzar, I had a sever reaction, which caused me to have many seizures. This caused me to developed PRES, which in turn has caused me to have brain damage.When I came out of my induced coma I did not know where I was, nor did I know who my family members were. I could no ...
Recent related drug studies:
- A study of drug interactions between Keppra Xr, Depakote Er for a patient with Seizure Disorder. The patient has Erectile Dysfunction (Erection problems)
- A study of drug interactions between Dilantin-125, Depakote, Vimpat, Keppra for a patient with Seizures. The patient has Cerebral Palsy, Seizure Cluster
- A study of drug interactions between Oxycodone Hydrochloride, Keppra, Divalproex Sodium, Alprazolam, Zonisamide, Morphine Sulfate, Oxycontin for a patient with Pain, Grand Mal Seizure, Adjustment Disorder With Depressed Mood, Chronic Depression, Seizure Disorder, Pain In Extremity.
NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
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