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Review: Depakote Er and Xanax





Summary: drug interactions are reported among people who take Depakote Er and Xanax together.

This review analyzes the effectiveness and drug interactions between Depakote Er and Xanax. It is created by eHealthMe based on reports of 1,581 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Depakote Er and Xanax >>>

What are the drugs

Depakote er has active ingredients of divalproex sodium. It is often used in bipolar disorder. (latest outcomes from Depakote er 3,677 users)

Xanax has active ingredients of alprazolam. It is often used in stress and anxiety. (latest outcomes from Xanax 58,976 users)

On Nov, 25, 2014: 1,581 people who take Depakote Er, Xanax are studied

Depakote Er, Xanax outcomes

Drug combinations in study:
- Depakote Er (divalproex sodium)
- Xanax (alprazolam)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Depakote Er is effective14.29%
(1 of 7 people)
22.22%
(2 of 9 people)
28.57%
(2 of 7 people)
0.00%
(0 of 9 people)
40.00%
(2 of 5 people)
40.00%
(2 of 5 people)
50.00%
(1 of 2 people)
n/a
Xanax is effective0.00%
(0 of 3 people)
57.14%
(4 of 7 people)
42.86%
(3 of 7 people)
50.00%
(3 of 6 people)
33.33%
(4 of 12 people)
50.00%
(2 of 4 people)
71.43%
(5 of 7 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
ComaDrug Exposure During PregnancyType 2 Diabetes MellitusVentricular Septal DefectNauseaDizzinessThrombosisAnxiety
InsomniaVentricular Septal DefectBlood Cholesterol IncreasedDrug Exposure During PregnancyVomitingFallWeight IncreasedDiabetes Mellitus
Intentional OverdoseAtrial Septal DefectBlood Triglycerides IncreasedType 2 Diabetes MellitusPainLoss Of ConsciousnessPerirectal AbscessType 2 Diabetes Mellitus
Eosinophilic PneumoniaAnaemiaMusculoskeletal DisorderBlood Cholesterol IncreasedType 2 Diabetes MellitusCystitisType 2 Diabetes MellitusDepression
DepressionRespiratory DistressBack PainAtrial Septal DefectSleep Apnoea SyndromePalpitationsObesityHeadache
DyspnoeaFoetal Distress SyndromeDiabetic NeuropathyApnoeaHyperglycaemiaBurning SensationBreast MassWeight Increased
Acute Respiratory Distress SyndromeApnoeaNeuropathy PeripheralAnaemiaDiabetic NeuropathyBlood Count AbnormalDiarrhoeaInsomnia
SomnolenceAnxietySpinal Column StenosisRespiratory DistressHypoglycaemiaBlood Triglycerides IncreasedDiabetic KetoacidosisNausea
NeutropeniaAortic DisorderHyperlipidaemiaFoetal Distress SyndromeDiabetic ComaConvulsionDiabetes Mellitus Inadequate ControlDizziness
Loss Of ConsciousnessSepsisDiabetes MellitusBack PainConvulsionFull Blood Count DecreasedThrombophlebitis SuperficialPain

Drug effectiveness by gender :

FemaleMale
Depakote Er is effective18.52%
(5 of 27 people)
25.00%
(4 of 16 people)
Xanax is effective44.83%
(13 of 29 people)
41.18%
(7 of 17 people)

Most common drug interactions by gender * :

FemaleMale
HeadacheDiabetes Mellitus
DepressionAnxiety
AnxietyType 2 Diabetes Mellitus
Type 2 Diabetes MellitusNausea
Diabetes MellitusDepression
DizzinessVomiting
InsomniaWeight Increased
Weight IncreasedSuicidal Ideation
DyspnoeaAgitation
PainInsomnia

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Depakote Er is effectiven/an/a0.00%
(0 of 1 people)
4.76%
(1 of 21 people)
15.38%
(2 of 13 people)
14.29%
(3 of 21 people)
16.67%
(2 of 12 people)
16.67%
(1 of 6 people)
Xanax is effectiven/an/an/a14.29%
(3 of 21 people)
23.53%
(4 of 17 people)
40.91%
(9 of 22 people)
27.27%
(3 of 11 people)
33.33%
(2 of 6 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Neonatal Respiratory Distress SyndromeOverdoseWeight IncreasedOverdoseType 2 Diabetes MellitusAnxietyInsomniaFall
Premature BabyHepatic FailurePancreatitis AcuteSuicide AttemptDiabetes MellitusDepressionType 2 Diabetes MellitusLoss Of Consciousness
Drug Withdrawal Syndrome NeonatalComaDiabetes Mellitus Inadequate ControlDiabetes MellitusWeight IncreasedType 2 Diabetes MellitusHypertensionAnaemia
Drug Exposure During PregnancyBrain DamageDiabetes MellitusConvulsionNauseaDiabetes MellitusDiabetes MellitusDizziness
Agitation NeonatalGastric DisorderType 2 Diabetes MellitusArthralgiaPainDepressionArteriosclerosis Coronary Artery
HyperglycaemiaWeight IncreasedAnxietyHeadacheHeadacheBurning Sensation
HyperinsulinaemiaHyperammonaemiaDepressionInsomniaAnxietyPalpitations
Glucose Tolerance ImpairedAbdominal PainDizzinessNeuropathy PeripheralAbdominal PainHeadache
Urinary RetentionMetabolic AcidosisObesitySuicidal IdeationLoss Of ConsciousnessWeight Decreased
Tremor NecObesityVision BlurredChest PainBack PainUrinary Tract Infection

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Depakote Er and Xanax?

You are not alone! Join a related mobile support group:
- support group for people who take Depakote Er and Xanax
- support group for people who take Depakote Er
- support group for people who take Xanax

Can you answer these questions (Ask a question):

  • Can clyndamican cause a seizure while taking depakote
    I am currently taking Depakote Extended Realease 1000mgs at bedtime with Clyndamican an antibiotic. I have been feeling dizzy, fatigue, headaches, body aches, sore throat, and pain and pressure in my chest. I would like to know if these two medications mixed together are causing me these problems, and if it can cause me a seizure.
  • I have been told by my gastroenterologist that i have gastroparesis, what are my treatment options, if any?
    I've had a CT scan and a Gastric Emptying study completed. My stomach is only 35% emptied after 4 hours, it should be at least 90% empty at that point. I have a colonoscopy and esophagealendoscopy scheduled for the first week of the year. What are my treatment options at this point?
  • Any information on deaths from taking lyica and high doses of alprazolam (1 answer)
    My Mother was a healthy 89 yr old with no healt issues, she was put on anxiety medicine, which she took regularly. She was also taking Lyric and had just started her Macular degeneration shots. She was prone to bladder infections and we went to the dr. for that, labs showed high calcium, within one week I had to take her to the emergency room, within one day she was on oxygen, within three days she was in the ICU intubated and unresponsive. She remained in ICU for 4 days had renal failure and died two days later.
  • Can nuvigil (vs adderall) be used simultaneously to help wean off 60mg/day of adderall? (1 answer)
    I have been on Adderall 30mg 2x daily for years!! I've had it lowered to 20mg, I've TRIED to go months without it (when not working) however I feel I've built up a tolerance level to the point that it's not as effective as it once was. My personal life has detoured WAY past anything an ADHD medication can possibly help as far as focusing on NEEDED tasks etc. I end up feeling wrapped up in what I'm doing at the moment that my anxiety increases due to all that I haven't been able to accomplish. I take various medications for various reasons, depression, anxiety, bulimia etc., and for the most part the doses have varied based on circumstances and current need at said time of prescription.. MY FAMILY HAS A HISTORY OF HEART DISEASE, And realizing that I'm already on the highest Adderall dosage scares me (and THEN as I think about it, it makes my heart race!). I've also noticed increased muscle spasms as well as extreme and intense pressure on my jaw (TMJ). MY QUESTION IS: does anyone have any experience LOWERING their Adderall dosage AND adding Nuvigil? The research I've done to date gives me impression that it could help balance out the more extreme effects of Adderall (60mg/day) but that the nuvigil would or could potentially help with the EXTREME exhaustion I feel as Adderall wears off. Some days I just crash, some days I sleep fine and others no matter how hard I tryyyy, I just CAN'T fall asleep, therefore making the next day worse! IDEALLY I'D LIKE TO BE MED FREE, right now I need them, but am hoping maybe I can speak with my doctor to lower Adderall and add Nuvigil to help wean me off the amphetamines as well as lower dosage intake. YES, a lot of the anxiety, sleeplessness and depression are related to current circumstances in my life, however, where I am is not where I want to be or where I'm headed.. Life is a journey, and all my meds have become a part of a journey I never thought I'd find myself taking. I don't want life/meds to define me, or create a me I no longer recognize, because scarily enough that seems to be a common pattern. As I overcome each and every daily obstacle, I also don't want to be "hooked" on my meds or needing "more" to wake up/sleep/function.. I'd like to work on finding a solution towards weaning off my meds NOW, and work my way off slowly, primarily the Adderall. I'm hoping by suggesting to my doctor and showing him my research he may agree (IF ITS EVEN A LOGICAL COMBO, CLEARLY IM NOT A DOCTOR) nuvigil could help me. I've already started taking less of my anti depressants, trazadone and xanax without discussing with doc because he is always busy.. My next appt I want to go in fully prepared with a plan and an overall goal to REDUCE my Adderall dose, but overall, I'm clueless!!! I have no idea what other meds other than nuvigil "could" potentially help if at all. I could be entirely wrong, Anyone with any experience using one vs other or both simultaneously, or anyone with constructive input, PLEASE COMMENT/SHARE!!
  • Is there some kind of self help that works for stopping nightmares
    HELP! I am sick and tired (literally) of getting 5-6 nightmares per week. I sleep well but at waking time I get nightmares related to two main anxieties in my life. I cannot go off meds. Can I take them in smaller dosages, beak the dosing times during the day. I know it is the fault (mostly) of Pristiq. But what to do? I already do Yoga, bedtime relaxation routine, and a lot of healthy other stuff. HELP if you have kicked this problem.

More questions for: Depakote Er, Xanax

You may be interested at these reviews (Write a review):

  • Xanax xr lives up to it's claim.
    I get annoyed reading so many negative reviews of Xanax XR. I assume those come from thrill-seeking drug addicts. Therapeutically I find Xanax XR to be a genius idea - and it works like it should. Xanax was aleady long-established as (probably the most) effective anti-anxiety & anti-panic agent, that also does wonders for things like 'social phobia'. But the problem was always that Xanax wore off too quickly, leaving the patient in a state of wanting more. I know, I was one of those patients. Then came along Xanax XR: meant to deliver the same drug over an extended period of time. It does that just fine, I don't need to carry around a bottle of pills to have my next dose at-the-ready. Xanax XR does the job for a solid 8-12 hours (I give a range because I never actually counted the hours.). The best part is that I feel the first beneficial effect only 30 minutes after taking Xanax XR - I don't have to wait 2 hours. It's forumlated well. Sorry that drug junkies can't get a 'rush' from it. But it is Xanax and it does last all day.
  • Xanax almost killed me!
    I took xanax and went to bed, I woke up in hospital. I had been there a long time in a coma. They were about to take me off life support! All because of xanax.
  • Benadryl completed suicide 50 year old
    My mother comitted suicide by taking a bottle of Benadryl. She also had been drinking, she had taken xanax and drank beer, she also took 300 Benadryl pills and started having seizures and went to the hospital was brain dead and her heart stopped the next morning.
  • Zoplicine /and /xanax taken together
    I am wondering if zopocline is compatible with Xanax. I have taken the together and had no adverse effects. Has any had this experience?
  • Seizure patient was on depakote for 16 years now on keppra 1500 mg.
    I am 28 years old and been off depakote for 5 months. I started keppra to control my seizure disorder, which works great. But for the past year I have developed osteoarthritis in my thoracic, si joints, and lumbar. I get alot of muscle hypersensitivity and pain. Can any of this be due to long term effects of seizure meds?

More reviews for: Depakote Er, Xanax

Comments from related studies:

  • From this study (6 months ago):

  • Leg/left weakness and gives out
    Degenerative disc disease
    L1 S5 herniation/bulging
    Numbness tingling loss of use and feeling left leg
    Severe pain

    Reply

  • From this study (9 months ago):

  • After doubling my Depakote dose, my abdomen is swollen and I am so dizzy and hallucinating so badly I can barely read. My nausea and pain are so severe, very effective drugs at doses that are a significant amount to my system are barely helping. Due to the weather and thus swelling of my previous Chiai Malformation Decompression Brain Surgery site, I have significant and debilitating headache pain and other Chiari symptoms are much worse than usual.

    Reply

  • From this study (2 years ago):

  • I was in a car accident in 2000. My lower back was trashed, and had to be reconstructed basically. I have fusions and titanium, all of this as causd many other health problems to arise over the last 10 years. But, I live a pretty normal life, most people don't even know there is anything wrong with me. : )

    Ultracet and Ultram, any drug from that family can be very dangerous, I had a serious reaction with Ultracet. I had 3 seizures before we figured out what was happening to me.

    Solu-Medrol was used in the hospital through my IV, for a complicated migraine problem. I do not know if I had some kind of allergic reaction to it, or if that drug just does that to people, but, I was ripping the IV out of my arm! I couldn't stand it! It felt like fire ants were under every inch of my skin crawling and biting me all the way down and back up my arms and legs! It took hours to stop, and it did not help the migraine either.

    Reply

    Allergic... on Mar, 6, 2013:

    allergic reaction to vancomycin and sulfamethoxazole....
    I was given vancomycin through an iv 2 days ago. Today I decided to take some sulfamethoxazole and the allergic reaction is unbearable. It's been 4 hrs and the burning aching hasn't stopped. How did u manage to stop the allergic reaction. I'm wondering if I should wait it out or go into er.

    Reply

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Complete drug side effects:

On eHealthMe, Depakote Er (divalproex sodium) is often used to treat bipolar disorder. Xanax (alprazolam) is often used to treat stress and anxiety. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

   

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