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Review: Depakote Er and Xanax

This review analyzes the effectiveness and drug interactions between Depakote Er and Xanax. It is created by eHealthMe based on reports of 1,581 people who take the same drugs from FDA and social media, and is updated regularly.

Stay connected: join a mobile support group for people who take Depakote Er and Xanax >>>

What are the drugs

Depakote er (what 3,672 Depakote Er users reported?) has active ingredients of divalproex sodium. It is used in bipolar disorder.

Xanax (what 58,899 Xanax users reported?) has active ingredients of alprazolam. It is used in stress and anxiety.

On Sep, 13, 2014: 1,581 people who take Depakote Er, Xanax are studied

Depakote Er, Xanax outcomes

Drug combinations in study:
- Depakote Er (divalproex sodium)
- Xanax (alprazolam)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Depakote Er is effective14.29%
(1 of 7 people)
22.22%
(2 of 9 people)
28.57%
(2 of 7 people)
0.00%
(0 of 9 people)
40.00%
(2 of 5 people)
40.00%
(2 of 5 people)
50.00%
(1 of 2 people)
n/a
Xanax is effective0.00%
(0 of 3 people)
57.14%
(4 of 7 people)
42.86%
(3 of 7 people)
50.00%
(3 of 6 people)
33.33%
(4 of 12 people)
50.00%
(2 of 4 people)
71.43%
(5 of 7 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
ComaDrug Exposure During PregnancyType 2 Diabetes MellitusVentricular Septal DefectNauseaDizzinessThrombosisAnxiety
InsomniaVentricular Septal DefectBlood Cholesterol IncreasedDrug Exposure During PregnancyVomitingFallWeight IncreasedDiabetes Mellitus
Intentional OverdoseAtrial Septal DefectBlood Triglycerides IncreasedType 2 Diabetes MellitusPainLoss Of ConsciousnessPerirectal AbscessType 2 Diabetes Mellitus
Eosinophilic PneumoniaAnaemiaMusculoskeletal DisorderBlood Cholesterol IncreasedType 2 Diabetes MellitusCystitisType 2 Diabetes MellitusDepression
DepressionRespiratory DistressBack PainAtrial Septal DefectSleep Apnoea SyndromePalpitationsObesityHeadache
DyspnoeaFoetal Distress SyndromeDiabetic NeuropathyApnoeaHyperglycaemiaBurning SensationBreast MassWeight Increased
Acute Respiratory Distress SyndromeApnoeaNeuropathy PeripheralAnaemiaDiabetic NeuropathyBlood Count AbnormalDiarrhoeaInsomnia
SomnolenceAnxietySpinal Column StenosisRespiratory DistressHypoglycaemiaBlood Triglycerides IncreasedDiabetic KetoacidosisNausea
NeutropeniaAortic DisorderHyperlipidaemiaFoetal Distress SyndromeDiabetic ComaConvulsionDiabetes Mellitus Inadequate ControlDizziness
Loss Of ConsciousnessSepsisDiabetes MellitusBack PainConvulsionFull Blood Count DecreasedThrombophlebitis SuperficialPain

Drug effectiveness by gender :

FemaleMale
Depakote Er is effective18.52%
(5 of 27 people)
25.00%
(4 of 16 people)
Xanax is effective44.83%
(13 of 29 people)
41.18%
(7 of 17 people)

Most common drug interactions by gender * :

FemaleMale
HeadacheDiabetes Mellitus
DepressionAnxiety
AnxietyType 2 Diabetes Mellitus
Type 2 Diabetes MellitusNausea
Diabetes MellitusDepression
DizzinessVomiting
InsomniaWeight Increased
Weight IncreasedSuicidal Ideation
DyspnoeaAgitation
PainInsomnia

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Depakote Er is effectiven/an/a0.00%
(0 of 1 people)
4.76%
(1 of 21 people)
15.38%
(2 of 13 people)
14.29%
(3 of 21 people)
16.67%
(2 of 12 people)
16.67%
(1 of 6 people)
Xanax is effectiven/an/an/a14.29%
(3 of 21 people)
23.53%
(4 of 17 people)
40.91%
(9 of 22 people)
27.27%
(3 of 11 people)
33.33%
(2 of 6 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Neonatal Respiratory Distress SyndromeOverdoseWeight IncreasedOverdoseType 2 Diabetes MellitusAnxietyInsomniaFall
Premature BabyHepatic FailurePancreatitis AcuteSuicide AttemptDiabetes MellitusDepressionType 2 Diabetes MellitusLoss Of Consciousness
Drug Withdrawal Syndrome NeonatalComaDiabetes Mellitus Inadequate ControlDiabetes MellitusWeight IncreasedType 2 Diabetes MellitusHypertensionAnaemia
Drug Exposure During PregnancyBrain DamageDiabetes MellitusConvulsionNauseaDiabetes MellitusDiabetes MellitusDizziness
Agitation NeonatalGastric DisorderType 2 Diabetes MellitusArthralgiaPainDepressionArteriosclerosis Coronary Artery
HyperglycaemiaWeight IncreasedAnxietyHeadacheHeadacheBurning Sensation
HyperinsulinaemiaHyperammonaemiaDepressionInsomniaAnxietyPalpitations
Glucose Tolerance ImpairedAbdominal PainDizzinessNeuropathy PeripheralAbdominal PainHeadache
Urinary RetentionMetabolic AcidosisObesitySuicidal IdeationLoss Of ConsciousnessWeight Decreased
Tremor NecObesityVision BlurredChest PainBack PainUrinary Tract Infection

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Get connected! Join a mobile support group:
- group for people who take Depakote Er and Xanax
- group for people who take Depakote Er
- group for people who take Xanax

Comments from related studies:

  • From this study (3 months ago):

  • Leg/left weakness and gives out
    Degenerative disc disease
    L1 S5 herniation/bulging
    Numbness tingling loss of use and feeling left leg
    Severe pain

    Reply

  • From this study (5 months ago):

  • After doubling my Depakote dose, my abdomen is swollen and I am so dizzy and hallucinating so badly I can barely read. My nausea and pain are so severe, very effective drugs at doses that are a significant amount to my system are barely helping. Due to the weather and thus swelling of my previous Chiai Malformation Decompression Brain Surgery site, I have significant and debilitating headache pain and other Chiari symptoms are much worse than usual.

    Reply

  • From this study (2 years ago):

  • I was in a car accident in 2000. My lower back was trashed, and had to be reconstructed basically. I have fusions and titanium, all of this as causd many other health problems to arise over the last 10 years. But, I live a pretty normal life, most people don't even know there is anything wrong with me. : )

    Ultracet and Ultram, any drug from that family can be very dangerous, I had a serious reaction with Ultracet. I had 3 seizures before we figured out what was happening to me.

    Solu-Medrol was used in the hospital through my IV, for a complicated migraine problem. I do not know if I had some kind of allergic reaction to it, or if that drug just does that to people, but, I was ripping the IV out of my arm! I couldn't stand it! It felt like fire ants were under every inch of my skin crawling and biting me all the way down and back up my arms and legs! It took hours to stop, and it did not help the migraine either.

    Reply

    Allergic... on Mar, 6, 2013:

    allergic reaction to vancomycin and sulfamethoxazole....
    I was given vancomycin through an iv 2 days ago. Today I decided to take some sulfamethoxazole and the allergic reaction is unbearable. It's been 4 hrs and the burning aching hasn't stopped. How did u manage to stop the allergic reaction. I'm wondering if I should wait it out or go into er.

    Reply

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Complete drug side effects:

On eHealthMe, Depakote Er (divalproex sodium) is often used to treat bipolar disorder. Xanax (alprazolam) is often used to treat stress and anxiety. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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