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Review: taking Diltiazem and Avapro together

Summary: drug interactions are reported only by a few people who take Diltiazem and Avapro together.

This review analyzes the effectiveness and drug interactions between Diltiazem and Avapro. It is created by eHealthMe based on reports of 3 people who take the same drugs from FDA and social media, and is updated regularly.





You are not alone: join a mobile support group for people who take Diltiazem and Avapro >>>

What are the drugs

Diltiazem hydrochloride has active ingredients of diltiazem hydrochloride. It is often used in high blood pressure. (latest outcomes from 6,567 Diltiazem hydrochloride users)

Avapro has active ingredients of irbesartan. It is often used in high blood pressure. (latest outcomes from 11,958 Avapro users)

On Feb, 4, 2015: 3 people who take Diltiazem Hydrochloride, Avapro are studied

Diltiazem Hydrochloride, Avapro outcomes

Drug combinations in study:
- Diltiazem Hydrochloride (diltiazem malate)
- Avapro (irbesartan)

Drug effectiveness over time :


Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
n/an/an/aPulmonary Embolismn/an/an/aNausea
NoduleMetastases To Liver
Interstitial Lung DiseasePain In Extremity
HysterectomyUrinary Retention
CoughWeight Decreased

Drug effectiveness by gender :


Most common drug interactions by gender * :

Pulmonary EmbolismNausea
NoduleMetastases To Liver
Interstitial Lung DiseasePain In Extremity
HysterectomyUrinary Retention
CoughWeight Decreased

Drug effectiveness by age :


Most common drug interactions by age * :

n/an/an/an/an/an/aMuscle SpasmsNausea
Pain In Extremity
Urinary Retention
Weight Decreased
Metastases To Liver

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Diltiazem and Avapro?

You are not alone! Join a related mobile support group:
- support group for people who take Diltiazem and Avapro
- support group for people who take Avapro
- support group for people who take Diltiazem Hydrochloride

Can you answer these questions (Ask a question):

  • I have heard that taking clonazepam and diltiazem can cause bronchitis anyone have this reaction
    I have bronchitis at least once a year, excess mucus and throat clearing. Tightening of the airways, mostly at night.was wondering if drug interactions could be the cause.
  • has diltiazem caused anxiety in anyone else?
    I have had the implant for 7 years. Recently the doc was concerned about more frequent palpations and my blood pressure was up. So first I was put on a couple blood pressure pills, but just a couple weeks. Then they took me off of those and put me on the Diltiazem. When anxiety skyrocketed and I ended up in the hospital, they put me on the Lorazepam. It worked pretty well for a day or two. But the anxiety is creeping back up. I took a cup of CalMag this morning and it helped bring it down to reasonable. Is it possible that the medication is what is causing the serious anxiety? I have never been anxious like this. And it fill me with adrenaline and then I just feel worse.
  • I take klonopin and diltiazem (calcium channel blocker blood pressure medicine) and am concerned about side effects. my accupuncturist recommends the ashwagandha. anyone have any issues with this?
    I take these prescription medications but have been going to an accupuncturist since 2012. I have trouble sleeping at night without my clonazepam and take naps during the day and am having trouble losing weight. She thinks that my adrenal glands may be fatigued and told me to try something called Adrenal Response which contains Sensoril Ashwagandha. When I looked up Ashwaganda it said that it could interact with the Clonazepam or Klonopin and also with High blood pressure medication. I am a little concerned. I mentioned this to her and she said they both are metabolized by the liver and it should be ok to take it, just to take it an hour or more after I take the Clonazepam. Has anyone had any issues with interactions with their prescribed meds while taking Ashwagandha? I don't want to have to monitor my blood pressure because my blood pressure medication works good for me. Any help would be appreciated because I want to try it but I am a little scared too. Thanks, Crystal
  • I want a yes or no on taking tylenol with lyrica
    Just want to know if it is safe to take Tylenol and Lyrica with a yes or no.
  • Unbearable fatigue and irbesartan (1 answer)
    I've been on Avapro for years and years. No side effects. I got switched somehow to irbesartan 150 and am exhausted it makes me feel like I am dying.
    I have to take four naps a day and don't have time to take care of anything.
    I am in bed at seven pm.

    Has anyone had this reaction to the generic?? it happend to me once with topamax
    before Trade vs generic. My life is always in bed. Naps betwen patietns, bed a six thirty. No energy to clean house or do ANYTHNG. HELP ??????? Am I DYING???

More questions for: Avapro, Diltiazem Hydrochloride

You may be interested at these reviews (Write a review):

  • Avapro back pain and other symptoms along the way.
    Been taking avapro for last 6 years and every now and then a weird symptom surfaces.
    In the begining it was tiredness no energy, then it was several near misses on the hiway because the drug interfered wih my brain/ vision, then unexplained bruising, mental fog,severe thirst,dry cough,not very good bp control, slows urination, and when my dosage was upped I now have middle back pain and front rightside pain ...not diagnosed yet but i feel my gallbladder is acting up.
  • Developing hypertension after starting diltiazem
    I was prescribed diltiazem to control the rapid ventricular response when in atrial fibrillation. I DID NOT HAVE HYPERTENSION at the time I started diltiazem. After 2 years my blood pressure kept creeping up at the doctor's office and at work (I'm an RN). It was consistently running 140's- 160's over 90's. Once I had an ablation procedure & was cured of paroxysmal atrial fibrillation I stopped the dilitazem & bought a BP monitor. Within about 18 days my blood pressure was returning to normal and has been ever since (nearly a year). It is now running 100's- 130's over 60's- 80's. Today 136/69; yesterday 117/73, etc. I have no doubt diltiazem caused me to have hypertension. With the exception of Eloquis prior to the ablation, at no time on the dilitiazem was I on any other new medication I had not already been taking.

More reviews for: Avapro, Diltiazem Hydrochloride

Complete drug side effects:

On eHealthMe, Diltiazem Hydrochloride (diltiazem malate) is often used to treat high blood pressure. Avapro (irbesartan) is often used to treat high blood pressure. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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