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Review: taking Diphenhydramine and Aspirin together

Summary: drug interactions are reported among people who take Diphenhydramine and Aspirin together.

This review analyzes the effectiveness and drug interactions between Diphenhydramine and Aspirin. It is created by eHealthMe based on reports of 2,638 people who take the same drugs from FDA and social media, and is updated regularly.

 

 

 

 

You are not alone: join a mobile support group for people who take Diphenhydramine and Aspirin >>>

What are the drugs

Diphenhydramine hydrochloride has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia. (latest outcomes from 3,006 Diphenhydramine hydrochloride users)

Aspirin has active ingredients of aspirin. It is often used in blood clots. (latest outcomes from 164,583 Aspirin users)

On Feb, 22, 2015: 2,638 people who take Diphenhydramine Hydrochloride, Aspirin are studied

Diphenhydramine Hydrochloride, Aspirin outcomes

Drug combinations in study:
- Diphenhydramine Hydrochloride (diphenhydramine hydrochloride)
- Aspirin (aspirin)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Diphenhydramine Hydrochloride is effective7.14%
(1 of 14 people)
0.00%
(0 of 4 people)
0.00%
(0 of 4 people)
44.44%
(4 of 9 people)
37.50%
(3 of 8 people)
44.44%
(4 of 9 people)
60.00%
(3 of 5 people)
n/a
Aspirin is effective0.00%
(0 of 5 people)
14.29%
(1 of 7 people)
50.00%
(2 of 4 people)
0.00%
(0 of 5 people)
46.15%
(6 of 13 people)
33.33%
(2 of 6 people)
80.00%
(4 of 5 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Renal FailurePleural EffusionUrine Output IncreasedSyncopeDeathFebrile NeutropeniaNight SweatsPain
PainNeuropathy PeripheralExcoriationConvulsionConvulsionPneumoniaDizziness AggravatedAnxiety
AnxietyArthralgiaPostoperative IleusHaemorrhageCardiac ArrestInsomniaRestless Leg SyndromeDyspnoea
InjuryAcute Respiratory FailureIleusCardiac ArrestHaemorrhageProductive CoughPruritus AggravatedNausea
FearDepressionHyponatraemiaFallSinusitisHaemorrhoidsFeeling JitteryFatigue
AnhedoniaCardiac Failure CongestiveConstipationDizzinessHepatic EncephalopathyBlood Bicarbonate DecreasedDiarrheaVomiting
Renal InjuryAnxietyDry MouthPneumoniaGastrooesophageal Reflux DiseaseBlood Creatinine IncreasedHematospermiaInjury
Emotional DistressAtrial FibrillationHallucinationPulse AbsentComplications Of Transplanted LiverInfectionWeight Above NormalDiarrhoea
Multi-organ FailurePlatelet Count DecreasedMicturition UrgencyHepatitis CParacentesisDiarrhoeaTrigeminal NeuralgiaAnaemia
Renal ImpairmentRenal FailureDizziness PosturalPeritonitis BacterialBlood Pressure Systolic DecreasedHypokalaemiaMyocardial InfarctionAsthenia

Drug effectiveness by gender :

FemaleMale
Diphenhydramine Hydrochloride is effective26.32%
(5 of 19 people)
29.41%
(10 of 34 people)
Aspirin is effective35.71%
(5 of 14 people)
32.26%
(10 of 31 people)

Most common drug interactions by gender * :

FemaleMale
PainDyspnoea
AnxietyPain
NauseaAnxiety
DyspnoeaFatigue
VomitingRenal Failure
FatigueInjury
DiarrhoeaDizziness
FallDepression
AnaemiaPneumonia
InjuryNausea

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Diphenhydramine Hydrochloride is effectiven/an/an/a16.67%
(1 of 6 people)
14.29%
(1 of 7 people)
15.79%
(3 of 19 people)
19.05%
(4 of 21 people)
23.08%
(6 of 26 people)
Aspirin is effectiven/an/an/a0.00%
(0 of 5 people)
20.00%
(1 of 5 people)
27.78%
(5 of 18 people)
40.00%
(6 of 15 people)
12.50%
(3 of 24 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Respiratory Syncytial Virus InfectionHepatitis CPyrexiaNauseaPainAnxietyAnxietyPain
Staphylococcal InfectionHaemolysisMultiple Drug Overdose IntentionalAbdominal Pain UpperCompleted SuicidePainPainDyspnoea
Orthostatic HypotensionLiver Function Tests Nos AbnormalSomnolenceVomitingWeight IncreasedEmotional DistressNauseaAnxiety
Alanine Aminotransferase IncreasedLethargySuicide AttemptPericardial EffusionNeck PainInjuryInjuryFatigue
HypotensionHepatitis C Antibody PositiveDizzinessHeadacheVomitingDyspnoeaDyspnoeaNausea
Renal Failure AcuteInfectious MononucleosisVomitingDyspnoeaArthralgiaNauseaDepressionDiarrhoea
Bronchial HyperreactivityFatigueChillsConvulsionAnxietyCardiac Failure CongestiveHeadacheAnaemia
Aspartate Aminotransferase IncreasedPainInsomniaAnaemiaVomitingVomitingAsthenia
EosinophiliaConvulsionUrinary Tract InfectionNauseaDepressionAnaemiaRenal Failure
CandidiasisGastric HaemorrhageBronchitisOedema PeripheralPain In ExtremityDiarrhoeaVomiting

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Diphenhydramine and Aspirin?

You are not alone! Join a related mobile support group:
- support group for people who take Diphenhydramine and Aspirin
- support group for people who take Aspirin
- support group for people who take Diphenhydramine Hydrochloride

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    I was also given intravenous antibiotics prior to and during surgery. i am wondering if this could have exacerbated Myasthenia Gravis symptoms that are usually controlled by mestinon.

More questions for: Aspirin, Diphenhydramine Hydrochloride

You may be interested at these reviews (Write a review):

  • Sids/benedryl infant stopped breathing
    We are devastated. Our grand daughter was being breastfed and mother only took 1 tablet of Benedryl 25 mg and healthy baby girl died of SIDS following morning. Any information is appreciated.
  • Diphenhydramine and mental acuity
    For at least 10 years, I have taken diphenhydramine 50 mg. at bedtime for insomnia and allergies. The results have been that I sleep well with no hangover or any cognitive impairment. If I experience vertigo from allergies, I may take an additional 50 mg. but never exceeding 100 mg in a 24 hour period.

    After reading the report regarding an Alzheimer's study finding that after taking as little as 4mg diphenhydramine daily for more than 3 years, dementia rates were high.

    I stopped the diphenhydramine one night. I experienced symptoms of deep brain pulsating pain and severe insomnia. After 4 hours, I took 50 mg diphenhydramine and slept very well. The next night I took 37.5 mg. diphenhydramine, slept very well. However, some of my tasks require layers of mental challenges in which I became slower.

    My question is how did the study recipients obtain 4 mg doses of diphenhydramine when the standard over-the-counter (OTC) availability in tablets is 25 mg? How reliable is the information submitted from the study subjects? What manufacturer's diphendramine was used, or were there several?

    I felt sharper mentally when on 50 mg daily than so far on 37.5 mg.
  • Sublingual b12 & insomnia
    Approx 8 months ago I began taking 500 mg sublingual B12 in the am. I actually feel more energized (real or imagined?) but, I have also begun experiencing severe insomnia. I go to sleep easily but get up around 3 times a night. This interrupted sleep is a killer. Any suggestions will be appreciated
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    First time I used Symbicort Inhaler, I immediately coughed freely, but noticed it was bright red, blood. Second time I used it- same thing. Third time I used it, I coughed about an hour later a larger amount of blood in phlegm. I'm reluctant to use the medication any further-I will consult my doctor after the weekend.

More reviews for: Aspirin, Diphenhydramine Hydrochloride

Comments from related studies:

  • From this study (7 months ago):

  • BP ranges 125-130 over 75-87 when getting up prior to meds to 90-50 sometimes in the evening. I am a little stressed and so diphenhydramine helps me sleep along with melatonin. THese are OTC

    Reply

  • From this study (9 months ago):

  • 27 L knee operations, three massive L knee infections resulting in a third and final arthoplasty revision. Extensive soft tissue damage resulting in perminante subqutanious sutuers and locking full leg brace, also perminante.

    Daily swelling in the knee joint (4 to 6 cm daily). Constant pain as well as additional pain when walking.

    Reply

  • From this study (12 months ago):

  • have been abstinent for 6 weeks; one testicle and penis became grossly swollen and painful, Dr. treated with Sulfamethox 2DSx twice daily-in six days had anaphylactic reaction hives,etc. so discontinued; after swelling subsided and resumption of sex,have had three bloody ejaculations.
    Have had quadruple heart bypass,AAA,permanent thrombosis in leg from vein harvest, double (saddlebag) pulmonary emboli.

    Reply

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Complete drug side effects:

On eHealthMe, Diphenhydramine Hydrochloride (diphenhydramine hydrochloride) is often used to treat insomnia. Aspirin (aspirin) is often used to treat blood clots. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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