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Review: Doxycycline and Azithromycin

This review analyzes the effectiveness and drug interactions between Doxycycline and Azithromycin. It is created by eHealthMe based on reports of 734 people who take the same drugs from FDA and social media, and is updated regularly.

Stay connected: join a mobile support group for people who take Doxycycline and Azithromycin >>>

What are the drugs

Doxycycline (latest outcomes from 13,622 users) has active ingredients of doxycycline hyclate. It is often used in acne.

Azithromycin (latest outcomes from 12,317 users) has active ingredients of azithromycin. It is often used in sinusitis.

On Jul, 14, 2014: 734 people who take Doxycycline, Azithromycin are studied

Doxycycline, Azithromycin outcomes

Drug combinations in study:
- Doxycycline (doxycycline hyclate)
- Azithromycin (azithromycin)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Doxycycline is effective25.00%
(1 of 4 people)
0.00%
(0 of 3 people)
n/a0.00%
(0 of 2 people)
50.00%
(1 of 2 people)
n/an/a0.00%
(0 of 1 people)
Azithromycin is effective25.00%
(1 of 4 people)
0.00%
(0 of 2 people)
100.00%
(1 of 1 people)
0.00%
(0 of 2 people)
n/an/an/a0.00%
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
DyspnoeaAstheniaExhaustion, Fatigue, Lethargy, Tiredness, WearinessDepressionDepressionDepressionDepressionAnxiety
Glomerulonephritis MembranousDyspnoeaMuscle TwitchingAbnormal BehaviourAnxietyAnxietyAnxietyPain
PainNeuropathy PeripheralMemory ImpairmentSuicide AttemptSuicide AttemptAggressionDizzinessNausea
Drug IneffectivePainMuscle CrampsHypoacusisAggressionNightmareHeadacheDyspnoea
FatigueLimb DiscomfortTinnitusHeadacheSuicidal IdeationIrritabilityPanic AttackPain In Extremity
Respiratory Tract CongestionDysphagiaDvtInjuryNightmareParanoiaPalpitationsBack Pain
Weight DecreasedDehydrationJoint StiffnessPainPsychotic DisorderSuicidal IdeationSuicidal IdeationDepression
HyperhidrosisIll-defined DisorderSinusitisIntentional OverdosePsychotic DisorderVomiting
Drug Level IncreasedHyperprolactinaemiaHeart InjuryIrritabilityPoor Quality SleepDizziness
NauseaRenal FailureMigraineAbnormal BehaviourIntentional OverdoseFatigue

Drug effectiveness by gender :

FemaleMale
Doxycycline is effective50.00%
(2 of 4 people)
0.00%
(0 of 8 people)
Azithromycin is effective33.33%
(1 of 3 people)
14.29%
(1 of 7 people)

Most common drug interactions by gender * :

FemaleMale
PainAnxiety
AnxietyAnaemia
NauseaChest Pain
DyspnoeaDyspnoea
Pain In ExtremityFatigue
VomitingNausea
InjuryHeadache
DepressionWeight Decreased
AstheniaBack Pain
DizzinessDepression

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Doxycycline is effectiven/an/a0.00%
(0 of 1 people)
0.00%
(0 of 1 people)
16.67%
(1 of 6 people)
0.00%
(0 of 2 people)
n/a12.50%
(1 of 8 people)
Azithromycin is effectiven/an/a0.00%
(0 of 1 people)
0.00%
(0 of 1 people)
0.00%
(0 of 4 people)
0.00%
(0 of 2 people)
n/a25.00%
(2 of 8 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Premature Babyn/aNauseaFatigueDepressionAnxietyAnxietyDyspnoea
Maternal Drugs Affecting FoetusEmotional DistressAnaemiaAnxietyDepressionInjuryPain
HaemorrhageAstheniaPain In ExtremityBack PainPainAnxiety
CholelithiasisAbdominal Pain UpperDyspnoeaPainNauseaInjury
AnaemiaNauseaPainNauseaArthralgiaBone Disorder
AnxietyDeep Vein ThrombosisNauseaArthralgiaNeck PainCardiac Failure Congestive
Irritable Bowel SyndromeKeloid ScarHyperhidrosisDysuriaPain In ExtremityNausea
Lip DryNight SweatsMyalgiaEar PainInsomniaTooth Extraction
Intestinal ObstructionPain In ExtremityBronchitisVomitingDyspnoeaOsteoarthritis
Cholecystitis ChronicChest PainFatigueDiarrhoeaDizzinessSinusitis

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Get connected! Join a mobile support group:
- group for people who take Doxycycline and Azithromycin
- group for people who take Azithromycin
- group for people who take Doxycycline

Comments from related studies:

  • From this study (6 days ago):

  • I have so many side effects that chronic fatigue seems simplistic. Almost every cell in my body has been damaged. I have seen over 20 doctors since my cascade of symptoms started (13years ago). They all play dumb, tell me my problem is not in their specialty, or offer me antidepressants. Yet when I look up actual research, I see that most of the pieces of the physiology of my syndrome have been known for years (some for decades).

    I also note that on this web site, there is no way to report a high number of side effects or simplify them as mitochondrial damage.

    I believe it is the intent of this web site, the AMA, drug companies, and most doctors to deliberately avoid "knowing" about the holocaust of poisoning that is occurring in the name of heath care.

    The logarithmical explosion of cancer, obesity, depression, allergies, auto-immune diseases, "rare genetic diseases," and diabetes (to name just a few) matches exactly the explosion of pharmaceutical consumption.

    It would be appropriate to apply the scientific method instead of the profit motive to further human health.

    Reply

    Hope22 on Jul, 9, 2014:

    Is doxycyclin among these drugs that have been given a black box warning for anyone with mitochondrial disease?

    Reply

    noscreenname on Jun, 23, 2014:

    person,
    if you have lyme, youre 75% of 100 likely to have either mycoplasma, or serratia. these cause kidney stones, which in turn, cause damage or loss if not surgically removed (struvite type) AND the way the spirochete and other partner bacteria hide from the meds. The lyme docs have known this all along when they said, "it hides where meds cannot get to it". 75% of lymies having myco...= struvite stones that will keep ANY coinfections going on indefinitely via relapse. Its all about meal ticket patients here....sad.

    Reply

    kilo on rappahannock on Jun, 27, 2014:

    I did have lyme, but it was treated immediately at the appearance of the classic rash. I have been tested several times since - always negative. I looked up mycoplasma and serratia, as you suggested, but found almost none of the symptoms apply to my problems. Thank you for the information. I can now pass that info on to anyone with those sort of symptoms. My symptoms can all be explained by mitochondrial damage caused by doxycycline and azithromycin. Thanks again for your reply. We all need to teach each other as much as possible, as the doctors won't do it.

    Reply

    noscreenname on Jul, 6, 2014:

    hi kilo,
    you know, negative test does not EVER mean no lyme. This is how it works: most tests look for the actual bug; not the lyme test. Lyme test looks for your antibodies to lyme. In raging lyme, bacteria far outnumber the antibodies you can make to fight it. Think of each antibody, as a key that fits in a germ's lock. Once met, the two die together - the antibody can no longer 'react' on the test. test uses dead lyme bacteria, and waits for antibodies to latch on, = positive. Raging infection = millions of busy antibodies, cant register this test. ONLY recovering lymies usually see the positive tests, because antibiotics have now put a dent in the bacterial population.
    NEVER ever rely on a negative lyme test. All docs ought to know this. The lab report directs them with these words, as well. Symptoms = #1 diagnosis for lyme. and for you and anyone else reading: ELISA test, is for rash stage. BLOT, is for anything after the first month. My son, got a lyme rash from mosquito bites midwest - he was treated on the spot, with lyme abx -- guess what? 20 days later, broke out in bartonella stripes, looks like stretch marks - lyme brings with it other bacteria, 10 of them if you look it up, almost more often than the lyme bacteria itself = and none of them, respond to the lyme meds - they all need different meds. Hence, if you had the bullseye rash, were treated with doxy etc, you could have the other co infections that dont respond to doxy etc and need a specialist. Doxy shouldnt cause any damage like youre describing. If it made you feel ill, this is called a herxheimer reaction and indicates bacterial die off. (I could not stand doxy when first found with lyme advanced - made me 300% worse while on it, but its a good sign).
    good luck

    Reply

    kilo on rappahannock on Jul, 7, 2014:

    Doxy and azithromycin both can cause mitochondrial damage. Both were prescribed, taken, and began my problems before I got Lyme and was treated with yet more doxy, which caused even more serious mitochondrial damage. Large doses of ubiquinol allow my to function at a passible level.

    Any and all antibiotics damage your immune system and can allow further infections. Some cause mitochondrial damage. Many other drugs can also cause mitochondrial damage. A huge number of drugs have been recently given black box warnings for anyone with mitochondrial disease. It is also true (though not yet admitted by the FDA) that many of those drugs can cause the mitochondrial damage in the first place.

    Reply

  • From this study (2 years ago):

  • Tim J on Jul, 10, 2011:

    I took this drug and it killed 40 percent of my achilles tendon.

    Reply

    George P on May, 7, 2012:

    I developed torticollis soon after starting abilify. At the same time, I developed pain in my left side. An MRI revealed 4 ruptured disks in my spine, a known cause of torticollis.

    Conclusion: I have no idea (neither, it seems, do the doctors). But I found abilify very effective for its purpose.

    Reply

Can you answer these questions (what is this?):

More questions for: Azithromycin, Doxycycline

You may be interested at these reviews (what is this?):

  • Symptons from taking doxycyclin
    I recently went in for a physical, everything was normal except my Creatinine levels. I had severe symptoms from burning hands/knuckles to feeling very tingly like cold needles. Also, burned very easily from sun even with 50 sun screen applied. Should I be worried about the Creatinine levels be abn ...

  • Azithromycin side effect skin hyperpigmentation
    My 6-year-old daughter took 5-day course azithromycin 3 times in 5 months for sinus infections. Do not recall exactly when hyperpigmentation began appearing all over front of neck, but definitely by the 3rd month after initial dose, with subsequent darkening upon taking two more prescriptions within ...

  • Doxycycline/severe sun reaction
    Was put on Doxycycline for an infection on the surface of my knee.Went to a football game in NC,SEPT.14TH,was in sun for maybe 3-4 hours.I have Virgilio but have been in sun many times with no such burn.Also used 45 sunblock! Went to doctor following Monday,because of concern for infection,she s ...

More reviews for: Azithromycin, Doxycycline

Complete drug side effects:

On eHealthMe, Doxycycline (doxycycline hyclate) is often used to treat acne. Azithromycin (azithromycin) is often used to treat sinusitis. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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