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Review: Doxycycline and Azithromycin





Summary: drug interactions are reported among people who take Doxycycline and Azithromycin together.

This review analyzes the effectiveness and drug interactions between Doxycycline and Azithromycin. It is created by eHealthMe based on reports of 734 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Doxycycline and Azithromycin >>>

What are the drugs

Doxycycline has active ingredients of doxycycline hyclate. It is often used in acne. (latest outcomes from Doxycycline 13,674 users)

Azithromycin has active ingredients of azithromycin. It is often used in sinusitis. (latest outcomes from Azithromycin 12,345 users)

On Dec, 2, 2014: 734 people who take Doxycycline, Azithromycin are studied

Doxycycline, Azithromycin outcomes

Drug combinations in study:
- Doxycycline (doxycycline hyclate)
- Azithromycin (azithromycin)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Doxycycline is effective25.00%
(1 of 4 people)
0.00%
(0 of 3 people)
n/a0.00%
(0 of 2 people)
50.00%
(1 of 2 people)
n/an/a0.00%
(0 of 1 people)
Azithromycin is effective25.00%
(1 of 4 people)
0.00%
(0 of 2 people)
100.00%
(1 of 1 people)
0.00%
(0 of 2 people)
n/an/an/a0.00%
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
DyspnoeaAstheniaExhaustion, Fatigue, Lethargy, Tiredness, WearinessDepressionDepressionDepressionDepressionAnxiety
Glomerulonephritis MembranousDyspnoeaMuscle TwitchingAbnormal BehaviourAnxietyAnxietyAnxietyPain
PainNeuropathy PeripheralMemory ImpairmentSuicide AttemptSuicide AttemptAggressionDizzinessNausea
Drug IneffectivePainMuscle CrampsHypoacusisAggressionNightmareHeadacheDyspnoea
FatigueLimb DiscomfortTinnitusHeadacheSuicidal IdeationIrritabilityPanic AttackPain In Extremity
Respiratory Tract CongestionDysphagiaDvtInjuryNightmareParanoiaPalpitationsBack Pain
Weight DecreasedDehydrationJoint StiffnessPainPsychotic DisorderSuicidal IdeationSuicidal IdeationDepression
HyperhidrosisIll-defined DisorderSinusitisIntentional OverdosePsychotic DisorderVomiting
Drug Level IncreasedHyperprolactinaemiaHeart InjuryIrritabilityPoor Quality SleepDizziness
NauseaRenal FailureMigraineAbnormal BehaviourIntentional OverdoseFatigue

Drug effectiveness by gender :

FemaleMale
Doxycycline is effective50.00%
(2 of 4 people)
0.00%
(0 of 8 people)
Azithromycin is effective33.33%
(1 of 3 people)
14.29%
(1 of 7 people)

Most common drug interactions by gender * :

FemaleMale
PainAnxiety
AnxietyAnaemia
NauseaChest Pain
DyspnoeaDyspnoea
Pain In ExtremityFatigue
VomitingNausea
InjuryHeadache
DepressionWeight Decreased
AstheniaBack Pain
DizzinessDepression

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Doxycycline is effectiven/an/a0.00%
(0 of 1 people)
0.00%
(0 of 1 people)
16.67%
(1 of 6 people)
0.00%
(0 of 2 people)
n/a12.50%
(1 of 8 people)
Azithromycin is effectiven/an/a0.00%
(0 of 1 people)
0.00%
(0 of 1 people)
0.00%
(0 of 4 people)
0.00%
(0 of 2 people)
n/a25.00%
(2 of 8 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Premature Babyn/aNauseaFatigueDepressionAnxietyAnxietyDyspnoea
Maternal Drugs Affecting FoetusEmotional DistressAnaemiaAnxietyDepressionInjuryPain
HaemorrhageAstheniaPain In ExtremityBack PainPainAnxiety
CholelithiasisAbdominal Pain UpperDyspnoeaPainNauseaInjury
AnaemiaNauseaPainNauseaArthralgiaBone Disorder
AnxietyDeep Vein ThrombosisNauseaArthralgiaNeck PainCardiac Failure Congestive
Irritable Bowel SyndromeKeloid ScarHyperhidrosisDysuriaPain In ExtremityNausea
Lip DryNight SweatsMyalgiaEar PainInsomniaTooth Extraction
Intestinal ObstructionPain In ExtremityBronchitisVomitingDyspnoeaOsteoarthritis
Cholecystitis ChronicChest PainFatigueDiarrhoeaDizzinessSinusitis

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Doxycycline and Azithromycin?

You are not alone! Join a related mobile support group:
- support group for people who take Doxycycline and Azithromycin
- support group for people who take Azithromycin
- support group for people who take Doxycycline

Can you answer these questions (Ask a question):

More questions for: Azithromycin, Doxycycline

You may be interested at these reviews (Write a review):

  • Adverse effect of azithromycin
    patients immunesystem showed very bad response to azithromycin adminstered as 1000mg per day 3 days and then 1000mg once a week for 6 weeks -

    a previously chronic sinuitis flared up as did a over 30 year old infection in a broken toe -

    dicillin was given for 10 days 3000mg per day / 1000mg 3 times daily - with good effect -

    the patents journal shows evidence of similar occurence a decade ago when taking Klacid uno also of the macrolid family -
    it appears macrolids can have severe adverse effect on some patients immunesystem
  • My experience with lyme
    My final semester at college-

    Woke up to extreme inflammation in what was determined to be a portion of my trapezius on the left side length of my next. It was accompanied by severely swollen lymph nodes throughout my entire body. I went about my day with what to me was seemingly a bad neck cramp and oncoming cold. In the afternoon I decided to participate in Track practice and what occurred after I am unsure about in terms of its relation to me performing physically or an autoimmune response against my peripheral nervous system. The next morning I woke up the left side of my trapezius was completely dysfunctional from its attachment to my cranium all the way down to the mid point of my back. It was accompanied by inflammation and sore pain at the point where the next connects to the shoulder girdle. Over the course of the next 8 months I went undiagnosed with Lyme, having seen neurologists and orthopedics in an attempt to find a solution. Reflecting on the first three months, I experienced significant effects on my emotional stability and cognitive capability. I would have severe mood swings--rage, depression, excitement-- and I would have difficulty with memory and train of thought- all of which can be confirmed by multitude of classmates. By the 8 month mark I had began to feel mild joint pain, particularly in areas I had formerly injured in athletic activity (ankles, lower back). At this point, my accessory nerve had not regenerated in terms of the portion affecting my trapezius, didn't regain any lost muscle function. I saw my physician, who discovered the Lyme infection. I took doxycycline over the next 3 months and saw significant improvement in my trapezius, which was accompanied by a decrease in lymph node size, as proven by comparison of MRIs. My fatigue dissipated and my moods/cognition returned to normal. I've regained about 70% of the function I formerly had with my trapezius (as compared to 0% prior to treatment). I wanted to write this because I have yet to see a similar case, understand the ambiguity of Lyme disease and the array of conditions it causes.
  • Symptons from taking doxycyclin
    I recently went in for a physical, everything was normal except my Creatinine levels. I had severe symptoms from burning hands/knuckles to feeling very tingly like cold needles. Also, burned very easily from sun even with 50 sun screen applied. Should I be worried about the Creatinine levels be abnormally high?
  • Azithromycin side effect skin hyperpigmentation (1 response)
    My 6-year-old daughter took 5-day course azithromycin 3 times in 5 months for sinus infections. Do not recall exactly when hyperpigmentation began appearing all over front of neck, but definitely by the 3rd month after initial dose, with subsequent darkening upon taking two more prescriptions within the 5 months. Disappeared after treating 1x/day for 2 days with aloe vera gel directly from the plant rubbed all over darkened areas; all hyperpigmentation scrubbed off with oatmeal/honey scrub on 3rd day. No recurrence until about 6 months later with minimal to moderate autumn sun exposure, recurrence all over front of neck again, even though never took azithromycin beyond the 3 prescriptions. About two weeks after this started, now entire side of one ankle is hyperpigmented. Very concerned how much more it will spread. Will up aloe vera gel application frequency in hopes to get rid of it. Stay away from this drug! It is definitely too new of a drug to be prescribing for kids!
  • Doxycycline/severe sun reaction
    Was put on Doxycycline for an infection on the surface of my knee.Went to a football game in NC,SEPT.14TH,was in sun for maybe 3-4 hours.I have Virgilio but have been in sun many times with no such burn.Also used 45 sunblock!



    Went to doctor following Monday,because of concern for infection,she started a new antibiotic and healing began. I am two weeks now ,into the burn and have large scabbed areas and a continued red,burning skin!!

More reviews for: Azithromycin, Doxycycline

Comments from related studies:

  • From this study (5 months ago):

  • I have so many side effects that chronic fatigue seems simplistic. Almost every cell in my body has been damaged. I have seen over 20 doctors since my cascade of symptoms started (13years ago). They all play dumb, tell me my problem is not in their specialty, or offer me antidepressants. Yet when I look up actual research, I see that most of the pieces of the physiology of my syndrome have been known for years (some for decades).

    I also note that on this web site, there is no way to report a high number of side effects or simplify them as mitochondrial damage.

    I believe it is the intent of this web site, the AMA, drug companies, and most doctors to deliberately avoid "knowing" about the holocaust of poisoning that is occurring in the name of heath care.

    The logarithmical explosion of cancer, obesity, depression, allergies, auto-immune diseases, "rare genetic diseases," and diabetes (to name just a few) matches exactly the explosion of pharmaceutical consumption.

    It would be appropriate to apply the scientific method instead of the profit motive to further human health.

    Reply

    Hope22 on Jul, 9, 2014:

    Is doxycyclin among these drugs that have been given a black box warning for anyone with mitochondrial disease?

    Reply

    noscreenname on Jun, 23, 2014:

    person,
    if you have lyme, youre 75% of 100 likely to have either mycoplasma, or serratia. these cause kidney stones, which in turn, cause damage or loss if not surgically removed (struvite type) AND the way the spirochete and other partner bacteria hide from the meds. The lyme docs have known this all along when they said, "it hides where meds cannot get to it". 75% of lymies having myco...= struvite stones that will keep ANY coinfections going on indefinitely via relapse. Its all about meal ticket patients here....sad.

    Reply

    kilo on rappahannock on Jun, 27, 2014:

    I did have lyme, but it was treated immediately at the appearance of the classic rash. I have been tested several times since - always negative. I looked up mycoplasma and serratia, as you suggested, but found almost none of the symptoms apply to my problems. Thank you for the information. I can now pass that info on to anyone with those sort of symptoms. My symptoms can all be explained by mitochondrial damage caused by doxycycline and azithromycin. Thanks again for your reply. We all need to teach each other as much as possible, as the doctors won't do it.

    Reply

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Complete drug side effects:

On eHealthMe, Doxycycline (doxycycline hyclate) is often used to treat acne. Azithromycin (azithromycin) is often used to treat sinusitis. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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