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Review: taking Elavil and Ambien together

Summary: drug interactions are reported among people who take Elavil and Ambien together.

This review analyzes the effectiveness and drug interactions between Elavil and Ambien. It is created by eHealthMe based on reports of 2,538 people who take the same drugs from FDA and social media, and is updated regularly.


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On Mar, 26, 2015: 2,538 people who take Elavil, Ambien are studied

Elavil, Ambien outcomes

Drug combinations in study:
- Elavil (amitriptyline hydrochloride)
- Ambien (zolpidem tartrate)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Elavil is effective7.69%
(1 of 13 people)
(2 of 18 people)
(0 of 6 people)
(0 of 9 people)
(3 of 6 people)
(1 of 4 people)
(2 of 4 people)
Ambien is effective44.44%
(4 of 9 people)
(2 of 10 people)
(5 of 10 people)
(7 of 15 people)
(5 of 10 people)
(1 of 6 people)
(3 of 3 people)

Drug effectiveness by gender :

Elavil is effective18.60%
(8 of 43 people)
(1 of 17 people)
Ambien is effective50.00%
(23 of 46 people)
(4 of 17 people)

Drug effectiveness by age :

Elavil is effective0.00%
(0 of 1 people)
(0 of 1 people)
(4 of 13 people)
(0 of 9 people)
(1 of 51 people)
(3 of 23 people)
(1 of 10 people)
Ambien is effective0.00%
(0 of 1 people)
(0 of 1 people)
(8 of 14 people)
(2 of 10 people)
(3 of 50 people)
(11 of 24 people)
(3 of 11 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
FatigueAmnesiaAtelectasisBack PainAmnesiaDepressionRenal Failure AcuteAnxiety
Speech DisorderLoss Of ConsciousnessTooth DisorderNeck PainAnxietyIntra-uterine DeathHoarsenessPain
Intra-uterine DeathRoad Traffic AccidentPneumoniaLoss Of ConsciousnessCellulitisAnxietyNasal Sinus DrainageDepression
HeadacheSomnolenceNeoplasm ProgressionRoad Traffic AccidentInjuryDrug IneffectiveIrritable Bowel Syndrome AggravatedNausea
NauseaNeck PainNeoplasm MalignantHeadacheRenal FailureLoss Of ConsciousnessSwelling In The AbdomenDyspnoea
FallCompleted SuicideMalnutritionConfusional StateLoss Of ConsciousnessDrug Withdrawal SyndromeSwelling Of The Ankles - Feet - LegsHeadache
AmnesiaUnresponsive To StimuliBone PainAmnesiaDepressionMuscle StrainAbnormal Weight GainBack Pain
AnxietyDrug IneffectiveRenal DisorderPost-traumatic Stress DisorderBlood Cholesterol IncreasedSpinal Compression FractureWeight GainAsthenia
Blood Pressure IncreasedSuicide AttemptHaemoglobin DecreasedAstheniaBlood Creatine Phosphokinase IncreasedUrinary Tract InfectionDry SkinArthralgia
Confusional StateHallucinationBone DisorderSleep Apnoea SyndromeDisturbance In AttentionDiverticulumDry MouthFatigue

Most common drug interactions by gender * :

DyspnoeaBack Pain
Back PainChest Pain

Most common drug interactions by age * :

Karyotype Analysis AbnormalAccidental Drug Intake By ChildAggressionAnxietyNauseaAnxietyPainAnxiety
Growth RetardationDizzinessCompleted SuicideNauseaAnxietyDepressionAnxietyPain
Flat FeetDyslaliaInsomniaMigraineChest PainPainNauseaDyspnoea
Neonatal DisorderPhonological DisorderInfluenza Like IllnessHeadacheBack PainBack PainArthralgiaAsthenia
Phalangeal HypoplasiaAkathisiaDyspnoeaDrug DependenceHeadacheOsteonecrosis Of JawBack Pain
Skin DisorderDrug IneffectiveMuscle SpasmsInsomniaDrug IneffectiveFallPneumonia
Psychomotor RetardationSomnolenceUrinary Tract InfectionVomitingFatigueDepressionArthralgia
Facial DysmorphismSocial PhobiaCondition AggravatedPainAstheniaPain In ExtremityDepression
EpilepsySuicide AttemptDepressionDepressionInsomniaPyrexiaHeadache
Congenital AnomalyDepressionDeep Vein ThrombosisHeadacheHypoaesthesiaHypoaesthesiaOsteoarthritis

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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- support group for people who take Ambien
- support group for people who take Elavil

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Elavil (amitriptyline hydrochloride) is often used to treat depression. Ambien (zolpidem tartrate) is often used to treat insomnia. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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