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Review: Elavil and Savella





Summary: drug interactions are reported among people who take Elavil and Savella together.

This review analyzes the effectiveness and drug interactions between Elavil and Savella. It is created by eHealthMe based on reports of 131 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Elavil and Savella >>>

What are the drugs

Elavil has active ingredients of amitriptyline hydrochloride. It is often used in depression. (latest outcomes from Elavil 11,891 users)

Savella has active ingredients of milnacipran hydrochloride. It is often used in fibromyalgia. (latest outcomes from Savella 3,389 users)

On Nov, 25, 2014: 131 people who take Elavil, Savella are studied

Elavil, Savella outcomes

Drug combinations in study:
- Elavil (amitriptyline hydrochloride)
- Savella (milnacipran hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Elavil is effectiven/a0.00%
(0 of 2 people)
50.00%
(2 of 4 people)
50.00%
(1 of 2 people)
0.00%
(0 of 2 people)
0.00%
(0 of 1 people)
50.00%
(2 of 4 people)
n/a
Savella is effective0.00%
(0 of 1 people)
42.86%
(3 of 7 people)
0.00%
(0 of 1 people)
66.67%
(2 of 3 people)
0.00%
(0 of 2 people)
n/an/an/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
DyspnoeaDrug AbuseMental Status ChangesMigraineMigrainen/aDry Eyes AggravatedNausea
PalpitationsSomnolenceConfusional StateDiscolored TeethGerdNauseaPain
Blood Glucose IncreasedNauseaBlood Pressure IncreasedJob ChangeFacet Joint SyndromeVision BlurredTremor
DiarrhoeaSerotonin SyndromeHallucination, VisualTeeth GrindingFibromyalgiaTeeth ClinchingSomnolence
Anaphylactic ShockDepressionAggressionTeeth ClinchingBack Pain - LowTeeth GrindingMigraine
Dermatitis ExfoliativeFeeling AbnormalDrug IneffectiveDry Eyes AggravatedMyofascial Pain SyndromeUrinary Tract InfectionMalaise
Protein Total DecreasedActivities Of Daily Living ImpairedWeight GainEagles SyndromeBlood UrinePainful Red EyesDrug Ineffective
Non-cardiac Chest PainHallucinationDepression AggravatedPainful Red EyesMood SwingsEagles SyndromeHeadache
Adverse Drug ReactionVision BlurredAlexiaFibromyalgiaWeight Gain - UnintentionalJob ChangeInjection Site Pain
MigraineAstheniaSweating - ExcessiveBack Pain - LowAbdominal PainDiscolored TeethSerotonin Syndrome

Drug effectiveness by gender :

FemaleMale
Elavil is effective33.33%
(5 of 15 people)
n/a
Savella is effective38.46%
(5 of 13 people)
0.00%
(0 of 1 people)

Most common drug interactions by gender * :

FemaleMale
NauseaSerotonin Syndrome
PainDrug Abuse
Tremor
Migraine
Somnolence
Malaise
Mental Status Changes
Headache
Depression
Drug Ineffective

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Elavil is effectiven/an/an/a12.50%
(1 of 8 people)
50.00%
(1 of 2 people)
0.00%
(0 of 1 people)
6.82%
(3 of 44 people)
n/a
Savella is effectiven/an/an/a22.22%
(2 of 9 people)
0.00%
(0 of 1 people)
n/a6.82%
(3 of 44 people)
n/a

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/an/an/aMigraineAbnormal Loss Of WeightInjection Site PainNauseaMental Status Changes
Poor Quality SleepDrug IneffectivePainPainHeadache
NauseaHypertensionDermatitis ExfoliativeAstheniaNausea
Suicidal IdeationScratchDiarrhoeaPalpitationsConfusional State
DizzinessRash MacularAnaphylactic ShockDizzinessPain
TremorLymph Node PainWaist Circumference IncreasedSerotonin SyndromeDyspnoea
DepressionFatigueAdverse Drug ReactionDyspnoeaMemory Impairment
Blood Pressure IncreasedLymphadenitisIntestinal ObstructionMalaiseAggression
GerdPainAbdominal DistensionTremorGait Disturbance
Myofascial Pain SyndromeDysuriaFallConstipationDrug Abuse

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Elavil and Savella?

You are not alone! Join a related mobile support group:
- support group for people who take Elavil and Savella
- support group for people who take Elavil
- support group for people who take Savella

Can you answer these questions (Ask a question):

  • Does amitriptyline increase eye pressure when you have acute angle closure glaucoma
    Does taking Amitriptyline increase eye pressure in a case of someone who has had acute angle closure glaucoma for 12 years?
  • I take 20mg of amitriptyline each notgh to help me sleep. i have just been diagnosed with parkinsons and need to takae azilect, whihc is an mao-b inhibotor, can i take them together
    Can I take both these tables together? My consultant said it was ok to take both
    but the Amitriptyline instructions say do not take with MAO-B inhibitors, Azilect is an MAO-B inhibitors
  • I cannot get a direct answer from any of my drs.,is my sciatic pain caused by my interstitail cystitus? (1 answer)
    I have had interstitail cystitus for almost four years now.I have been on every kind of drug,other than pain pills.I will not take them,I don't believe in them they only mask the problem and cause addiction.of course,just my belief.I have had d.s.m.o. repetitively for first year and a half twice a week.I have tried physical therapy .I have had five hydrodistention.I just recently had my first hydrodistention with botox injections.nothing has kept me out of pain .even when I am doing good I can only seem to reach a six in my pain level.my frequency average is and has been 30-40Times a day.I am,or,was a chef kitchen manager.could not perform and lost two jobs because of this disease.my flanks,my lower back ,my legs,my arms all ways in pain.pelvic pain is constant.I'd rather not go into further details way too personal.but this has taken my life.I am 35.I have led a fairly healthy life.I have no life now.I am seeking disability .Every Dr. I go to has a different option about the sciatic part of my problem some Dr.s are very sure and as a matter of fact about how it is in conjunction with I.c..others look at me like I'm nuts?why do I limp?why can't I get in and out of a car,or bend down and touch my toes,pick heavy stuff up.just to laugh at times hurts.this is my life ,I gotta wonder ,is there any one else out there going through the same symptoms and no relief?
  • Does bcaa cause migraines?
    I took 3 capsules of BCAA and within the next hour I developed a very aggressive migraine. Believing the migraine may have been separate to the tablets, I took another 3 capsules the next day and again within 1 hour I developed a very aggressive migraines. Has anyone had a similar adverse reaction?
  • I have cfs and have been treated for depression for years.will adderall replace the antidepressants ect that i'm taking now? (3 answers)
    I have a long history of depression and anxiety disorder.I was recently diagnosed with CFS.Now that I know exactly what this disease entails,everything makes perfect sense.My physical symptoms,with the exception of increased debilitating pain over the last 2 years, I had come to accept as normal! Glandular pain,thunderstorm headaches,sweating and chills and pure exhaustion. I have an appointment with my psyciatrist in a week to discuss Adderall. My family doctor wants to try it because i've been on EVERY antidepressant,add ons ect. out there but nothing helps my sheer exhaustion.She's not very familiar with lamotragene and wants his opinion first.Nothing works for me and I truely believe that because of my history with depression,CFS has been overlooked.



    My life has been a living hell. I have an 11yr old daughter,and i feel like i've been robbed of her childhood. Nothing else matters.I am divorced and because of my illness and lack of ability to look after her,I reserve every ounce of energy i have to spend with her. And even then....Mommy's always tired.This is not a life.I've isolated myself so much that all other relationships in my life i've let slip away.



    I've decreased the wellbutrin and lamotrogene before I see my Doctor so hopefully there will be NO reason for him to start me on Adderall.I'm putting so much hope into this treatment. I've used stimulants in the past(ephedrine,bennies)and that's the only time I've ever felt human in the past 10 years.

    I want this to work soooooo bad but i'm a little scared that I'm setting myself up for a fall.

    Any thoughts?

More questions for: Elavil, Savella

You may be interested at these reviews (Write a review):

  • Amitriptyline involuntary eye movements
    I've began having sparatic involuntary eye movements a few days after I started taking amitriptyline. It's not faint either, it's like my eye is having a seizure, emabrassing. Just wanted to share.
  • Drug interractions savella. amoxicillin
    Sudden ache, pain and neuropathy in right hand and wrist within 8 hours of sterting Amoxicillin.
  • Nausea and vomiting while taking savella
    I have been on Savella for 6 months now and the nausea has increased with time and now I also have vomiting daily along with occasional diarrhea. I am currently weaning off of the Savella, cutting the dosage in half for two weeks and then one pill every other day for two weeks, following my dr.'s instructions. I have three weeks total left and still have the nausea and vomiting but hopeful that these will start to go away soon. Anyone else who has weaned off of it- how long until your symptoms subsided?
  • So sleepy with savella
    I am just finishing the starter pack of Savella and I am so sleepy I can't hold my head up. My pain and other Fibromyalgia symptoms are tremendously better but I am sleeping like crazy. Hopefully I can have both doses at night and this will help. I am so glad to not be in pain but I need to be awake also. I am going to talk to my doctor about perhaps another medication to help curb the sleepiness. I can't use caffeine or stimulants due to anxiety but need something to take this sleepiness away.
  • Androgel for secondary hypogonadism
    Severe swelling in legs, ankles and feet after being on my feet for more than one hour. Pain in calves and ankles. Feels like they're being squeezed or compressed. Pain dissipates after laying down for a few hours. Swelling never completely dissipates. Always some swelling in ankles.

More reviews for: Elavil, Savella

Comments from related studies:

  • From this study (7 months ago):

  • Well as I said im taking
    savella and elatrol for fibromyalgia and depression.
    I have witnessed breast pain in my right breast someyimes left. Mostly itchy and the nipple hurts to a touch

    Reply

  • From this study (2 years ago):

  • Profuse Sweating
    Testosterone

    Reply

  • From this study (2 years ago):

  • Profuse Sweating

    Reply

Post a new comment    OR    Read more comments

Complete drug side effects:

On eHealthMe, Elavil (amitriptyline hydrochloride) is often used to treat depression. Savella (milnacipran hydrochloride) is often used to treat fibromyalgia. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

   

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