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Review: taking Enbrel and Plaquenil together

Summary: drug interactions are reported among people who take Enbrel and Plaquenil together.

This review analyzes the effectiveness and drug interactions between Enbrel and Plaquenil. It is created by eHealthMe based on reports of 7,669 people who take the same drugs from FDA and social media, and is updated regularly.

 

 

 

 

You are not alone: join a mobile support group for people who take Enbrel and Plaquenil >>>

What are the drugs

Enbrel has active ingredients of etanercept. It is often used in rheumatoid arthritis. (latest outcomes from 175,547 Enbrel users)

Plaquenil has active ingredients of hydroxychloroquine sulfate. It is often used in systemic lupus erythematosus. (latest outcomes from 15,548 Plaquenil users)

On Feb, 12, 2015: 7,669 people who take Enbrel, Plaquenil are studied

Enbrel, Plaquenil outcomes

Drug combinations in study:
- Enbrel (etanercept)
- Plaquenil (hydroxychloroquine sulfate)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Enbrel is effective50.00%
(3 of 6 people)
40.00%
(4 of 10 people)
75.00%
(6 of 8 people)
100.00%
(5 of 5 people)
37.50%
(3 of 8 people)
50.00%
(3 of 6 people)
100.00%
(1 of 1 people)
n/a
Plaquenil is effectiven/a50.00%
(3 of 6 people)
20.00%
(1 of 5 people)
28.57%
(2 of 7 people)
12.50%
(2 of 16 people)
0.00%
(0 of 3 people)
33.33%
(1 of 3 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Injection Site ErythemaDrug IneffectiveVaginal HaemorrhageFatigueRheumatoid ArthritisRheumatoid ArthritisPneumoniaInjection Site Pain
Rheumatoid ArthritisInjection Site ErythemaPelvic PainRheumatoid ArthritisArthralgiaFatigueLymphadenopathyRheumatoid Arthritis
HeadacheInjection Site PruritusSquamous Cell Carcinoma Of The CervixPneumoniaDrug IneffectiveNauseaLung NeoplasmInjection Site Erythema
HypersensitivityRheumatoid ArthritisPneumoniaCellulitisPyrexiaDizzinessAppendicitis PerforatedInjection Site Reaction Nos
Condition AggravatedArthralgiaCellulitisLung NeoplasmFatigueHeadacheOvarian CystArthralgia
Premature LabourOedema PeripheralLung NeoplasmEscherichia InfectionBreast CancerOsteoporosisPseudomonas InfectionInjection Site Haemorrhage
AstheniaInjection Site PainLymphadenopathyLymphadenopathyCondition AggravatedFallEscherichia InfectionNausea
Injection Site ReactionPneumoniaRheumatoid ArthritisBeta Haemolytic Streptococcal InfectionBack PainRashCellulitisInjection Site Swelling
PyrexiaEczemaArthralgiaLupus-like SyndromeNight SweatsArthralgiaBeta Haemolytic Streptococcal InfectionInjection Site Pruritus
PruritusPainNauseaHypotensionPneumoniaCondition AggravatedArthralgiaFatigue

Drug effectiveness by gender :

FemaleMale
Enbrel is effective56.76%
(21 of 37 people)
57.14%
(4 of 7 people)
Plaquenil is effective20.59%
(7 of 34 people)
33.33%
(2 of 6 people)

Most common drug interactions by gender * :

FemaleMale
Injection Site PainRheumatoid Arthritis
Rheumatoid ArthritisArthralgia
Injection Site ErythemaDrug Ineffective
Injection Site Reaction NosInjection Site Pain
Injection Site HaemorrhageCondition Aggravated
ArthralgiaInjection Site Reaction Nos
NauseaCough
FatiguePyrexia
Injection Site PruritusFatigue
Drug IneffectiveNausea

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Enbrel is effectiven/an/an/a50.00%
(1 of 2 people)
31.25%
(5 of 16 people)
30.77%
(8 of 26 people)
40.91%
(9 of 22 people)
33.33%
(2 of 6 people)
Plaquenil is effectiven/an/an/a0.00%
(0 of 1 people)
6.67%
(1 of 15 people)
13.04%
(3 of 23 people)
19.05%
(4 of 21 people)
16.67%
(1 of 6 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Congenital Cystic Kidney DiseaseUpper Respiratory Tract Infection NosInjection Site PainVaginal HaemorrhageInjection Site Reaction NosInjection Site Reaction NosInjection Site PainRheumatoid Arthritis
Palatal DisorderPsoriasisInjection Site ErythemaInjection Site ErythemaInjection Site ErythemaInjection Site ErythemaRheumatoid ArthritisInjection Site Reaction Nos
Urinary Tract InfectionPyrexiaNauseaPelvic PainInjection Site HaemorrhageRheumatoid ArthritisInjection Site Reaction NosInjection Site Pain
Respiratory Syncytial Virus InfectionInjection Site PainInjection Site PruritusInjection Site SwellingInjection Site PruritusInjection Site HaemorrhageInjection Site ErythemaInjection Site Haemorrhage
Reflux NephropathyInjection Site DiscolourationInjection Site HaematomaInjection Site Reaction NosInjection Site SwellingInjection Site PainInjection Site HaemorrhageDrug Ineffective
Bladder DiverticulumAutoimmune HepatitisDrug IneffectiveSquamous Cell Carcinoma Of The CervixInjection Site HaematomaArthralgiaArthralgiaArthralgia
Renal HypertrophyAbdominal Pain NosInjection Site RashInjection Site PainRheumatoid ArthritisFatigueOedema PeripheralDermatitis Nos
Clostridial InfectionWeight IncreasedVomitingInjection Site HaematomaInjection Site PainNauseaNauseaNausea
Otitis MediaInjection Site ErythemaClostridial InfectionInjection Site PruritusNauseaHeadacheFatigueInjection Site Erythema
Pericardial EffusionMouth UlcerationHospitalisationPremature LabourHeadache NosInjection Site SwellingPainCough

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of Enbrel and Plaquenil on

Do you take Enbrel and Plaquenil?

You are not alone! Join a related mobile support group:
- support group for people who take Enbrel and Plaquenil
- support group for people who take Enbrel
- support group for people who take Plaquenil

Recent conversations of related support groups:

Can you answer these questions (Ask a question):

  • Anyone experence colon cancer on enbrel?
    I used Enbrel for about 9 years and developed colon cancer. There is no family history and the particular DNA of the cancer was highly unusual for colon cancer. Has anyone else experienced colon cancer after long term Enbrel use?
  • Can daliresp cause sever lower back pain and light perioud bleeding?
    I started Daliresp tab.and i began having a really bad rash in my private parts .. by the 3rd day i started having awful pain in my lower back with some light blood in my urin, now i have this severe pain and its as if i have a light perioud. i had a comple hysterectomy in 2003,due to overian cancer. i will call my pulmonaligist who put me on this medication on monday the 26th . but i am concern thats why i am asking ...
  • Can vesicare aggravate my sjogren's syndrome?
    Can Vesicare aggravate my Sjogren's Syndrome symptoms?
    Can Vesicare increase my dryness in my eyes?
    Can Vesicare aggravate my IBS (Irritable Bowel Syndrome)?
  • Electrolyte imbalance due to diarrhea caused by enbrel
    Electrolyte loss caused by the diarrhea side effect treatment or resolving this problem
  • Is it safe to take demerol while taking tramadol hydrochloride and hydroxychloroquine (2 answers)
    I am experiencing acute, debilitating pain due to the Chikungunya virus, which has reintroduced all of the previous painful symptoms I have,ongoing and in the past, from Fibromyalgia, Arthritis, tendonitis and severe headaches. It's in its 38th day and I am basically crippled from neck to feet. Have to sleep propped up as arms throb with pain when horizontal. The only thing that has subdued the pain slightly are Oxycocet and Ibuprofen, but the pain never goes away. My hands and feet are so inflammed it's difficult to perform even the smallest tasks of personal hygiene and housekeeping. I have difficulty controlling my bladder and often don't make it to the washroom in time. Just started on Demerol today so will no longer take the Oxycocet, but am concerned of the interactions with Demerol, Hydroxychloroquine and Tramadol Hydrochloride extended release tablets that I take daily for the Fibromyalgia and Arthritis. I have dealt with a great deal of pain through the years, but I now have the pain of every serious illness I have had in my lifetime, all at the same time. I honestly didn't think a person could deal with this much pain at once. I have tried and am still taking several vitamins and herbal supplements as well as drinking tons of water and eating really well. Lots of berries, dark vegetables, apples, yogurt and minimal meat. Taking turmeric, papaya leaf, ginger, cinnamon and boswellia for the inflammation. Taking minimal wheat products, sugar and no alcohol. Also, drinking green, fennel and nettle tea daily. I know this is a lot of information, but I really need help and wonder if anyone has any suggestions! Thanking you in advance!!!

More questions for: Enbrel, Plaquenil

You may be interested at these reviews (Write a review):

  • Having leg cramps after 2 years on enbrel
    Started having leg cramps after using Enbrel for almsot 2 years. They start the day I give the injection and have lasted 1-3 days waking me several time in the middle of the night.
  • Ring in was with temasapam
    ringing in ears caused by temazepam.
    no problem with hydroxychlor
  • My experience on plaquenil
    I'm 32--& this report showed that eye twitching only occured in ages 40-49, I can't be the only 30 something having this issue. It is soo annoying it comes & goes daily most of the day. Is this a side effect of the drug, must be. Because if you just google eye twitching --it says the reasons are stress, lack of sleep & caffeine--I have problems with all the above..so medication or any of the above--dk
  • Hair loss with enbrel
    I have been on Enbrel for 4 months and started seeing significant hair thinning at the second month of treatments (50 mg once per week). My Rhuematologist suggested 800 mcg of folic acid. I am still losing hair although I am feeling so much better.
  • Etanercept and irritability
    I have been on Etanercept for 8 years for Psoriasis. Previous to this I was on
    Methotrexate, Cyclosporine, Retinodes and ACTH injections.Since being on 25mg twice a week I have been 98% clear.The only side effect to date is "Irritability" which lasts about 24hrs.
    This Drug has been my saving grace.

More reviews for: Enbrel, Plaquenil

Comments from related studies:

  • From this study (2 weeks ago):

  • I am currently experiencing constant muscle contractions in my abdomen and jerking movements in my neck and midsection. My neck will pull back by itself... Or while I'm standing I'll involuntarily bend over. I'm also having balance issues. I feel very unstable walking and am experiencing some tremors.

    Reply

  • From this study (13 months ago):

  • Severe Sleep Apnea

    Reply

  • From this study (1 year ago):

  • Incidence of peripheral neuropathy of the 2 drugs interacting resulting in severe "burning feet".

    Reply

Post a new comment    OR    Read more comments

Complete drug side effects:

On eHealthMe, Enbrel (etanercept) is often used to treat rheumatoid arthritis. Plaquenil (hydroxychloroquine sulfate) is often used to treat systemic lupus erythematosus. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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