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Review: taking Escitalopram Oxalate and Silenor together

Summary: drug interactions are reported among people who take Escitalopram Oxalate and Silenor together.

This review analyzes the effectiveness and drug interactions between Escitalopram Oxalate and Silenor. It is created by eHealthMe based on reports of 309 people who take the same drugs from FDA and social media, and is updated regularly.





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What are the drugs

Escitalopram oxalate has active ingredients of escitalopram oxalate. It is often used in depression. (latest outcomes from 3,818 Escitalopram oxalate users)

Silenor has active ingredients of doxepin hydrochloride. It is often used in insomnia. (latest outcomes from 48 Silenor users)

On Feb, 5, 2015: 309 people who take Escitalopram Oxalate, Silenor are studied

Escitalopram Oxalate, Silenor outcomes

Drug combinations in study:
- Escitalopram Oxalate (escitalopram oxalate)
- Silenor (doxepin hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Escitalopram Oxalate is effective0.00%
(0 of 1 people)
(0 of 3 people)
(3 of 4 people)
(1 of 2 people)
(0 of 1 people)
Silenor is effective0.00%
(0 of 1 people)
(0 of 1 people)
(0 of 1 people)
(1 of 3 people)
(1 of 1 people)
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Mental DisorderInsomniaDrug ToxicityDizzinessAggressionPancreatitisChronic DepressionPain
Cholecystitis ChronicHallucinationInsomniaRestlessnessMood SwingsHeadacheNausea
NervousnessFibromaOverdoseWeight DecreasedSleepiness - During The DayDrug IntoleranceAnxiety
InsomniaDiplopiaAngina PectorisNauseaIntentional OverdoseBlood Triglycerides IncreasedFall
DepressionIll-defined DisorderHypertensionPanic AttackHallucinationBlood Cholesterol IncreasedDiarrhoea
DiscomfortBlood Glucose IncreasedMultiple Sclerosis RelapseInsomniaAbnormal BehaviourHyperlipidaemiaOsteonecrosis Of Jaw
PainTooth DisorderWeight IncreasedSuicidal IdeationSuicide AttemptType 2 Diabetes MellitusPain In Extremity
Suicide AttemptJoint SwellingFat Tissue IncreasedNervousnessDepressionChronic DepressionChest Pain
Condition AggravatedType 2 Diabetes MellitusCondition AggravatedDysgeusiaMental DisorderConstipation
Suicidal IdeationHeadacheConvulsionDecreased AppetiteAmnesiaBack Pain

Drug effectiveness by gender :

Escitalopram Oxalate is effective37.50%
(3 of 8 people)
(1 of 3 people)
Silenor is effective40.00%
(2 of 5 people)
(0 of 3 people)

Most common drug interactions by gender * :

PainDrug Ineffective
NauseaSuicide Attempt
Pain In ExtremityDiabetes Mellitus
InsomniaMuscle Twitching
Chest PainInsomnia
DiarrhoeaDecreased Appetite
Osteonecrosis Of JawConstipation

Drug effectiveness by age :

Escitalopram Oxalate is effectiven/an/a100.00%
(1 of 1 people)
(1 of 1 people)
(1 of 4 people)
(0 of 2 people)
(1 of 3 people)
(0 of 1 people)
Silenor is effectiven/an/an/a0.00%
(0 of 1 people)
(1 of 3 people)
(1 of 2 people)
(0 of 2 people)
(0 of 1 people)

Most common drug interactions by age * :

Pancreatitisn/an/aPainDiabetes MellitusType 2 Diabetes MellitusInsomniaDrug Ineffective
Mental DisorderHeadacheDiabetes MellitusAnxietyDiarrhoea
DiscomfortType 2 Diabetes MellitusUrinary Tract InfectionInjuryTremor
Cholecystitis ChronicChest PainDiabetes Mellitus Inadequate ControlPainDecreased Appetite
Emotional DistressPanic AttackBlood Cholesterol IncreasedChest PainPain
DepressionDrug ToxicityDyspnoeaNauseaOedema Peripheral
Suicide AttemptSinus TachycardiaPainFallSuicide Attempt
InjuryRectal HaemorrhagePancreatitisOsteoarthritisRash
Fear Of DeathPalpitationsHeadachePain In ExtremitySuicidal Ideation
Completed SuicidePunctate KeratitisConstipationFoot FractureMuscle Twitching

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Escitalopram Oxalate and Silenor?

You are not alone! Join a related mobile support group:
- support group for people who take Escitalopram Oxalate and Silenor
- support group for people who take Escitalopram Oxalate
- support group for people who take Silenor

Can you answer these questions (Ask a question):

  • I am on nexplanon as well as lexapro. why do i start my period everytime i start taking it.
    I was put on Lexpro(escitalopram) about 6 months ago and I was scared to take the medicine I would take it about 2 days and I would start my period so I stopped. I began taking it again cause I feel like I need to stick it out and see what happens and I was not a 100% sure it was the Lexapro starting my periods cause I am on nexplanon as well. so my periods are almost not existent.I have been taking lexpro for about 4 days now and I started to bleed again. Is this something I need to be alarmed about? Do they have some type of horrible unknown reaction. I just want to hear some good news cause I want to stick with the Lexapro to see if it helps me at all. Thanks for your time.
  • Nose bleeds after meningioma surgery(post 11 months)
    I have been experiencing bloody nose, 3 in the last week. 2014 I had a meningioma removed, never experienced any bloody noses until now, I know it is dry because of winter, but there us no warning, it lasts for 20 min then it is gone no dizziness, I do have vertigo- slight case
  • I have quit smoking about 4 wks ago. i'm having nightmares for the 5 days. my question is do the nightmares taper off or do they never stop?
    I've been on lexapro for 7 yrs. This is the only med that works for me I've tired lots of diff meds for my anxiety/depression and the all made me nuts or want to die. Even the generic gave me nightmare so I stopped that one. I literally have little to no stress in my life either. So lexapro is the best for me. Anyway I'm getting healthy working out and I quit smoking about 4 wks ago. The nightmares have been going on all wk. They are stressing me out blah. When are these crazy stressful dreams gonna stop? Or at least tapper off?
  • What can i take for a headache when i am on lexapro (1 answer)
    lexapro started only a week ago, feel tightness in jaw and headache, sleeplessness, not sure if lexapro is good for me if i cannot ever take an aspirin or tylenol for sleep.
  • Has anyone been helped by taking lexapro and wellbutrin? (2 answers)
    I am the mom of a 22 year old who is trying to get through college and can't seem to find the right meds for depression. She is taking Lexapro and I am wondering if adding Wellbutrin will help.

More questions for: Escitalopram Oxalate, Silenor

You may be interested at these reviews (Write a review):

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    After two months on lexapro, Tourette's syndrome started and has continued for 18 months, increasing in intensity and frequency. After one month off the Lexapro, the Tourette's syndrome has stopped completely.
  • Escitalopram /narcolepsy
    Began taking escitalopram one month ago. Having narcoleptic type sleep incidents as well as unwanted suicidal thoughts. Legs and arms also go out. Sleeping up to thirteen or more hours per day.
  • Lexapro and memory loss
    I actually have no idea what other medicine I was on the week I took Lexapro, it was back at the end of February 2014 right before I checked myself into the psych hospital. I formed no memory for a whole week just because of one drug! My friends and family tell me what happened that week and I have called them a liar because there is no recall from that week! I have been on psychiatric drugs for over 14 years and have never had such a horrible reaction as I did with Lexapro! The side effects do not include this reaction, but I didn't sleep at all that week or so I am told and there is just nothing, not even a little memory. Take this as you will I am not saying everyone gets this side effect I am just saying it is not impossible. I learned a lesson I don't remember, but will never take Lexapro again! It was dangerous for me!
  • Patients having false positives while on remeron
    I have had a few patients complain they are failing drug tests for Amphetamines while on remeron, and have claimed to have not used any type of Amphetamine or any (Mixed Salts). These patients are all or were on probation, parole, or under some stipulation. Iv realized most of these patients are taking another psych med. The list consists of insomnia meds such as Ambien(zolpidem), Sonata(zaleplon),Lunesta(eszopiclone). Also the Anti-Depressants Lexapro (escitalopram)and Prozac (fluoxetine). One of my patients was on Diazepam (Valium). I have switched medicines, particularly the Ambien, Lexapro, and Prozac have reversed the false negative. I prescribe many of my patients remeron. I'm a big believer in its effects on my patients moods and everyday depression. I have heard this happening before, but this was the first time I have ever had this happen to one of my own patients.(These were 5 separate patients in the span of 16 months) Of course none of these patients were criminalized based on lab results, but the issue still lies there. I know this is common for a lot of script meds to give false positives for narcotics. This is just obviously one I am putting out there. Let me know if anyone has experienced something similar.

More reviews for: Escitalopram Oxalate, Silenor

Complete drug side effects:

On eHealthMe, Escitalopram Oxalate (escitalopram oxalate) is often used to treat depression. Silenor (doxepin hydrochloride) is often used to treat insomnia. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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