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Review: taking Fentanyl and Demerol together

Summary: drug interactions are reported among people who take Fentanyl and Demerol together.

This review analyzes the effectiveness and drug interactions between Fentanyl and Demerol. It is created by eHealthMe based on reports of 276 people who take the same drugs from FDA and social media, and is updated regularly.





You are not alone: join a mobile support group for people who take Fentanyl and Demerol >>>

What are the drugs

Fentanyl has active ingredients of fentanyl citrate. It is often used in pain. (latest outcomes from 14,400 Fentanyl users)

Demerol has active ingredients of meperidine hydrochloride. It is often used in pain. (latest outcomes from 4,937 Demerol users)

On Jan, 29, 2015: 276 people who take Fentanyl, Demerol are studied

Fentanyl, Demerol outcomes

Drug combinations in study:
- Fentanyl (fentanyl citrate)
- Demerol (meperidine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Fentanyl is effective100.00%
(1 of 1 people)
Demerol is effectiven/a0.00%
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Abdominal PainSleep DisorderRoad Traffic AccidentSubstance AbuseDental Cariesn/an/aPain
VomitingTremorDepressionDental CariesNausea
PainPanic AttackCondition AggravatedNauseaAnxiety
NauseaSubstance AbuseHead InjuryDepressionDepression
Liver Function Test AbnormalNauseaMulti-organ FailurePanic AttackAnaemia
ThrombocytopeniaWithdrawal SyndromeRespiratory DisorderSleep DisorderPyrexia
Chest PainDrug Withdrawal SyndromeUnresponsive To StimuliWithdrawal SyndromeVomiting
Muscle SpasmsDental CariesRadiculopathyTremorInjury
Neutropenic InfectionEmotional DistressPainToothacheOsteonecrosis Of Jaw
Cardiac ArrestAppetite DisorderMyocardial InfarctionPolysubstance DependenceBack Pain

Drug effectiveness by gender :

Fentanyl is effective100.00%
(1 of 1 people)
Demerol is effective0.00%
(0 of 1 people)

Most common drug interactions by gender * :

Back PainAbdominal Pain
Neck PainOsteonecrosis Of Jaw
Spinal OsteoarthritisAnxiety
Weight DecreasedDiabetes Mellitus

Drug effectiveness by age :

Fentanyl is effectiven/an/an/an/an/a100.00%
(1 of 1 people)
Demerol is effectiven/an/an/an/an/a0.00%
(0 of 1 people)

Most common drug interactions by age * :

Grand Mal Convulsionn/aPancytopeniaLiver Function Test AbnormalPyrexiaNauseaPneumoniaPain
Cholecystitis NosVomitingHaemorrhoidsNeck PainBronchitisNausea
CholelithiasisPainBack PainDepressionCoughAsthenia
Abdominal Pain NosChest PainAnaemiaPainAnaemiaOsteonecrosis Of Jaw
HaematemesisFebrile NeutropeniaPelvic PainDental CariesNauseaAbdominal Pain
Bile Duct Obstruction NosNauseaInjuryPyrexiaDyspnoeaCholelithiasis
Pain NosConfusional StateRash ErythematousBack PainPleural EffusionDiabetes Mellitus
Visual Disturbance NosMuscle SpasmsOverdoseAnhedoniaDizzinessDiarrhoea
Liver Function Tests Nos AbnormalNeutropenic InfectionNauseaImpaired HealingWeight IncreasedAnaemia
PruritusHallucinationFallIntervertebral Disc ProtrusionDepressionCholecystitis

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of Fentanyl and Demerol on

Do you take Fentanyl and Demerol?

You are not alone! Join a related mobile support group:
- support group for people who take Fentanyl and Demerol
- support group for people who take Demerol
- support group for people who take Fentanyl

Can you answer these questions (Ask a question):

  • Is it safe to take demerol while taking tramadol hydrochloride and hydroxychloroquine (2 answers)
    I am experiencing acute, debilitating pain due to the Chikungunya virus, which has reintroduced all of the previous painful symptoms I have,ongoing and in the past, from Fibromyalgia, Arthritis, tendonitis and severe headaches. It's in its 38th day and I am basically crippled from neck to feet. Have to sleep propped up as arms throb with pain when horizontal. The only thing that has subdued the pain slightly are Oxycocet and Ibuprofen, but the pain never goes away. My hands and feet are so inflammed it's difficult to perform even the smallest tasks of personal hygiene and housekeeping. I have difficulty controlling my bladder and often don't make it to the washroom in time. Just started on Demerol today so will no longer take the Oxycocet, but am concerned of the interactions with Demerol, Hydroxychloroquine and Tramadol Hydrochloride extended release tablets that I take daily for the Fibromyalgia and Arthritis. I have dealt with a great deal of pain through the years, but I now have the pain of every serious illness I have had in my lifetime, all at the same time. I honestly didn't think a person could deal with this much pain at once. I have tried and am still taking several vitamins and herbal supplements as well as drinking tons of water and eating really well. Lots of berries, dark vegetables, apples, yogurt and minimal meat. Taking turmeric, papaya leaf, ginger, cinnamon and boswellia for the inflammation. Taking minimal wheat products, sugar and no alcohol. Also, drinking green, fennel and nettle tea daily. I know this is a lot of information, but I really need help and wonder if anyone has any suggestions! Thanking you in advance!!!
  • Last night went to hospital as i was shaking and dizzy scared it was after my third dose of avelox. is this a side effect? i'm scared to take anything even my regular medications today was shaking
    Taken pain mess for years got chest infection was given avelox three days ago. Last nights dose I started shaking couldn't breathe so shaky yet I am dehydrated too. I had woke up drank coffee then took my mess regular and started shaking all over again. Drank three glasses of juice and two of water felt better but still off. I only take one dose of avelox a day and think I should stop it, should I?
  • What is the highest dose of demerol i can take at once and still be safe?
    I had major reconstructive back surgery
    With 2 titanium replaced vertebrae
    Fusion and pins holding 2 broken facet joints
    Together. I have post surgical herniation in
    Remaining vertebrae and post surgical nerve damage
    Radiating down both legs. Since Vicodin 750/750 has been taken off the market
    Nothing is helping me. My pain mgmt doctor is trying
    To help, but that means trying something new at a relatively low dose for a month then
    Reassessing. Which means I'm miserable for a month at a time if it's not working
    I'm almost out of options because nothing seems to be helping
    Years ago I had luck with Demerol injections in the hospital so I agreed to try Demerol pills now I'm stuck again with something that's not working. So my question is how many MHD of Demerol can I take at one time and still be safe. I have to survive until my next pain management appt June 4th
    And I'm in excrutiating pain. Any body know? Thank you
  • Does acetazolamide help with intra nasal ketamine controlling your pain longer? (1 answer)
    Thinking of having Ketamine infusion to reboot my Central Nervous System. I have been taking it in liquid form & nasally for the last year. Some relief but doesn't last! If I don't have RSD can it do me more harm than good??? Thank you for helping end the pain, I hope.
  • I was informed that sudden stoppage of the use of valium could cause death or stroke. is this correct?
    was using valium to help with back spasms and stress. stopped taking due to prescription expired. told that stopping "cold turkey" was extremely dangerous and could cause death or stroke

More questions for: Demerol, Fentanyl

You may be interested at these reviews (Write a review):

  • Living with chronic pain while battling with psychological disorders. (1 response)
    I have had back problems since 2004. I have been on pain management since 2007. A year ago I was diagnosed with Fibromyalgia. Not only does fibromyalgia cause deep wide spread pain, it also makes me feel lethargic, fluish, and greatly effects my daily life. I also have some psychological conditions as well. Mostly due to a traumatic event experienced as a child.
  • Savella & synthroid hell! (3 responses)
    Within 15 minutes of taking Savella, the heat starts in my face and the sweating begins unrelentlessly. And the palpitations begin right away and later will be strong enough to wake me from sleep. Its horrible! I cant go anywhere! I cant tolerate any additional heat anywhere! And if I go out, I must bring a towel with me... it overwhelms me! I hate this!!

More reviews for: Demerol, Fentanyl

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Complete drug side effects:

On eHealthMe, Fentanyl (fentanyl citrate) is often used to treat pain. Demerol (meperidine hydrochloride) is often used to treat pain. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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