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Review: Fentanyl and Topiramate





Summary: drug interactions are reported among people who take Fentanyl and Topiramate together.

This review analyzes the effectiveness and drug interactions between Fentanyl and Topiramate. It is created by eHealthMe based on reports of 129 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Fentanyl and Topiramate >>>

What are the drugs

Fentanyl has active ingredients of fentanyl citrate. It is often used in pain. (latest outcomes from Fentanyl 14,395 users)

Topiramate has active ingredients of topiramate. It is often used in migraine. (latest outcomes from Topiramate 8,369 users)

On Dec, 12, 2014: 129 people who take Fentanyl, Topiramate are studied

Fentanyl, Topiramate outcomes

Drug combinations in study:
- Fentanyl (fentanyl citrate)
- Topiramate (topiramate)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Fentanyl is effective0.00%
(0 of 1 people)
0.00%
(0 of 1 people)
0.00%
(0 of 1 people)
0.00%
(0 of 1 people)
100.00%
(1 of 1 people)
n/an/a0.00%
(0 of 1 people)
Topiramate is effectiven/an/an/an/a0.00%
(0 of 1 people)
0.00%
(0 of 2 people)
100.00%
(1 of 1 people)
0.00%
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
OverdoseOverdosePainDrug Withdrawal SyndromeAbnormal BehaviourFatigueContusionDepression
Drug Withdrawal SyndromeDrug DependenceObstruction GastricDrug IneffectiveTooth AbscessTachycardia IrregularLoss Of ConsciousnessDrug Dependence
Tooth LossDrug Withdrawal SyndromeFlank PainArthralgiaDrug DependenceAbdominal Pain AggravatedLoss Of HairDental Caries
DependenceDependenceCalculus UrethralTooth FractureDysarthriaNumbness And TinglingConvulsionPain
Dental CariesTooth LossPancreatitisTooth DisorderDental CariesNausea And VomitingMemory ImpairmentOverdose
Back PainDental CariesPancreatitis AcuteOsteomyelitisDepressionAbdominal NeoplasmVasodilatationDrug Withdrawal Syndrome
DepressionDepressionWeight IncreasedSensitivity Of TeethDrug AbuseMigraineHeadacheNausea
NauseaPainUrethral StenosisSinusitisDrug AbuserPain ExacerbatedPainDrug Ineffective
PainDrug AbuseType 2 Diabetes MellitusDental CariesBack InjuryBone And Joint PainFallTooth Loss
Suicidal IdeationDrug IneffectiveLoss Of HairOverdoseMuscle TwitchingFall

Drug effectiveness by gender :

FemaleMale
Fentanyl is effective20.00%
(1 of 5 people)
0.00%
(0 of 1 people)
Topiramate is effective25.00%
(1 of 4 people)
0.00%
(0 of 1 people)

Most common drug interactions by gender * :

FemaleMale
DepressionPain
OverdoseSuicidal Ideation
Drug DependenceDrug Dependence
FallAnxiety
VomitingDental Caries
Drug Withdrawal SyndromeVision Blurred
Drug IneffectiveDrug Withdrawal Syndrome
Dental CariesConstipation
ConvulsionPancreatitis
PainTooth Loss

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Fentanyl is effectiven/an/an/an/a100.00%
(1 of 1 people)
0.00%
(0 of 21 people)
0.00%
(0 of 1 people)
0.00%
(0 of 2 people)
Topiramate is effectiven/an/an/an/an/a0.00%
(0 of 21 people)
100.00%
(1 of 1 people)
0.00%
(0 of 2 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/aHyperammonaemic EncephalopathyNauseaPulmonary EmbolismArthralgiaDental CariesDrug IneffectiveElectrocardiogram Qt Prolonged
Abdominal Pain UpperPainNephrolithiasisDepressionPainChest Pain
CholelithiasisGallbladder InjuryPyrexiaAbnormal BehaviourUrethral StenosisAnxiety
VomitingAnxietyDrug Withdrawal SyndromeDysarthriaType 2 Diabetes MellitusHeadache
UrticariaOverdoseVascular RuptureDrug DependencePancreatitis AcutePain
PainApplication Site IrritationConvulsionOverdoseDrug DiversionVasodilatation
Gallbladder InjuryRenal FailureUrinary Tract InfectionConstipationDrug ToxicityFall
Cholecystitis ChronicGastrointestinal DisorderTooth AbscessVomitingConvulsion
Antibody Test PositiveUrticariaPainPancreatitisAngioedema
ProteinuriaInfluenza Like IllnessSerotonin SyndromeBreakthrough PainLip Pain

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Fentanyl and Topiramate?

You are not alone! Join a related mobile support group:
- support group for people who take Fentanyl and Topiramate
- support group for people who take Fentanyl
- support group for people who take Topiramate

Can you answer these questions (Ask a question):

  • Can nuvigil (vs adderall) be used simultaneously to help wean off 60mg/day of adderall? (1 answer)
    I have been on Adderall 30mg 2x daily for years!! I've had it lowered to 20mg, I've TRIED to go months without it (when not working) however I feel I've built up a tolerance level to the point that it's not as effective as it once was. My personal life has detoured WAY past anything an ADHD medication can possibly help as far as focusing on NEEDED tasks etc. I end up feeling wrapped up in what I'm doing at the moment that my anxiety increases due to all that I haven't been able to accomplish. I take various medications for various reasons, depression, anxiety, bulimia etc., and for the most part the doses have varied based on circumstances and current need at said time of prescription.. MY FAMILY HAS A HISTORY OF HEART DISEASE, And realizing that I'm already on the highest Adderall dosage scares me (and THEN as I think about it, it makes my heart race!). I've also noticed increased muscle spasms as well as extreme and intense pressure on my jaw (TMJ). MY QUESTION IS: does anyone have any experience LOWERING their Adderall dosage AND adding Nuvigil? The research I've done to date gives me impression that it could help balance out the more extreme effects of Adderall (60mg/day) but that the nuvigil would or could potentially help with the EXTREME exhaustion I feel as Adderall wears off. Some days I just crash, some days I sleep fine and others no matter how hard I tryyyy, I just CAN'T fall asleep, therefore making the next day worse! IDEALLY I'D LIKE TO BE MED FREE, right now I need them, but am hoping maybe I can speak with my doctor to lower Adderall and add Nuvigil to help wean me off the amphetamines as well as lower dosage intake. YES, a lot of the anxiety, sleeplessness and depression are related to current circumstances in my life, however, where I am is not where I want to be or where I'm headed.. Life is a journey, and all my meds have become a part of a journey I never thought I'd find myself taking. I don't want life/meds to define me, or create a me I no longer recognize, because scarily enough that seems to be a common pattern. As I overcome each and every daily obstacle, I also don't want to be "hooked" on my meds or needing "more" to wake up/sleep/function.. I'd like to work on finding a solution towards weaning off my meds NOW, and work my way off slowly, primarily the Adderall. I'm hoping by suggesting to my doctor and showing him my research he may agree (IF ITS EVEN A LOGICAL COMBO, CLEARLY IM NOT A DOCTOR) nuvigil could help me. I've already started taking less of my anti depressants, trazadone and xanax without discussing with doc because he is always busy.. My next appt I want to go in fully prepared with a plan and an overall goal to REDUCE my Adderall dose, but overall, I'm clueless!!! I have no idea what other meds other than nuvigil "could" potentially help if at all. I could be entirely wrong, Anyone with any experience using one vs other or both simultaneously, or anyone with constructive input, PLEASE COMMENT/SHARE!!
  • Can mrsa cause chronic intestinal pseudo obstruction?
    I had a small bowel obstruction caused by adhesions from an appendectomy carried out 20yrs previously and had grumbling pain ever since but been labelled a malingerer by my family GP until one day at work when I started with terrible tummy ache and sickness like I'd never known, fetching up bile with force. I hated going to hospital after yrs of being called a moaner but after a day of rolling round in pain, temperature of 103 an dehydration, my Mammy insisted we go and I was seen straight away - to my shock I was in theatre within 3hrs with a serious obstruction.
    I never really recovered... The obstruction returned after 2 days and a portion of necrotic bowel was removed, then further fever and cellulitis then MRSA and deaths door.... Isolation in high dependency (intensive care) wound break down, ventilated and all related issues that come with that - chest infection, pneumonia, bed sores. Total time in hospital 8 months. Negative pressure dressing on laparotomy wound, colostomy, picc, 4 rounds of vancomycin, minor flirt with heart failure (just water related) an eventually everything healed. Had a large incisional hernia to repair and some corrective work to the horrific scarring but then the neuropathy started plus problems eating, spewing up after any solid food, more than a few forks, diarrhoea and sickness or constipation nausea and pain driving me mad, tried all manner of drugs, nerve blocks, physio, floating tank, acupuncture, opiates, non opiates, spinal cord stimulation, an now a consultant just had a 'eureka' moment and said were you treated with vancomycin when you had MRSA? If so I'm pretty sure you have chronic intestinal pseudo obstruction and is 90% sure but wants to take a muscle biopsy to be certain. I've had so much surgery and bad news in the last 10yrs I'm terrified of germs, hospital acquired bugs and anaesthetics, is there any other way? Or can I have this test done awake - conscious sedation? I had it before during spinal cord surgery so I know what's involved and it's better than GA as I know what's going on, who is doing what to me etc...
    Does anyone with a medical background know about this ailment/disease? Does it sound feasible that MRSA or it's treatment could have caused this? I was surgically debrided up to every other day when the vac pac/negative pressure machine and dressings were changed and the doctors told me I lost a great deal of tissue and had a lot of nerve damage due to the infection.
    Any patient perspectives on this illness would also be very much valued in helping me make a decision, moving forward. If all this is going to accomplish is to attach a label to the pain but not actually change anything, after fighting it for 10yrs now, avoiding hospital as much as I can, I really can't see the point of exploratory surgerys and biopsys now when it is known that I have this propensity towards adhesions and a new wound means a potentially new adhesion growth site.
    If it helps, the appendectomy happened when I was 10yrs old, the MRSA when I was 30 and I am now 40.
    Beat Wishes.
  • Last night went to hospital as i was shaking and dizzy scared it was after my third dose of avelox. is this a side effect? i'm scared to take anything even my regular medications today was shaking
    Taken pain mess for years got chest infection was given avelox three days ago. Last nights dose I started shaking couldn't breathe so shaky yet I am dehydrated too. I had woke up drank coffee then took my mess regular and started shaking all over again. Drank three glasses of juice and two of water felt better but still off. I only take one dose of avelox a day and think I should stop it, should I?
  • Does topamax effect sexual desire and cause weight gain (1 answer)
    I have taken topamax for 10 years and have been gaining weight steadily every year. My doctor says the medication is not the reason because Topamax causes people to loose weight. I have also voiced my concerns to him that since I started taking this medication I have no desire for sex. He says this medication would not affect this. Please help so I can get him to change my medication.
  • Omeprazole or pantoprazole?
    I take an oral contraceptive, Diane-35 ED, which is not in the list of drugs to choose from on this site.

    Recently, the medication I was taking for my stomach ulcer (Omeprazole) became unavailable in my country of residence and was replaced by Patoprazole. I started taking it yesterday morning and by midday today the side effects were unbearable. I am nauseous, have diarrhea, and a very severe headache. This didn't happen with Omeprazole. Do you think this is a drug interaction or is there some difference between the two that I am perhaps sensitive to?

More questions for: Fentanyl, Topiramate

You may be interested at these reviews (Write a review):

  • Urea urine increased while taking topamax
    I was on Topamax to lose weight. It worked for me, I lost weight but my blood urea increased. I have to stop taking it.
  • Massive aggression within first 4 days at 50mg (1 response)
    am only taking 50mg and have only been taking it for 4 days(this is the evening of the 4th day)as a preventative for migraine headaches that I have suffered from from 16 years. I have had pins and needles in my hands and feet as well as spontaneous crying fits since day 2 and Major aggression since yesterday. With normally an insurmountable amount of patience with my 1 year old son, I outright yelled at him last night. This is unacceptable. I have never felt such quick and sudden rage over nothing before, well, over anything before.
  • Seizure disorder med problems (1 response)
    Velafaxine 150 mg. 1 per day.

    In process of switching from Topiramate 50 mg. 1 pill in morning & one at night (going off of this because of kidney stones) Was on this medication approximately 10 years.

    Lamotrigine 2 25mg pills in morning and 2 - 25 mg. pills at night.

    On the 3rd day of the 2nd week of switching I started the nightmares. I took a one hour nap and had a nightmare that seemed like it went on the entire time. Even if I slept for 20 minutes I had a dream or nightmare. I've sometimes been known to have vivid dreams but never this constant in my entire life. Also, very seldom do I have such terrible dreams. So many in one evening. They are an occasional thing, not an all night long thing.

    Also, I have sinus trouble occasionally. The same day the nightmares began I got a terrible headache behind my one eye and under my eye. I have no drainage yet anyway. Not sure if this is during the start up of this medicine, but if I had known it could cause trouble with sinus I would never have started it.

    I was put on this as a quick back up plan when the medicine we agreed upon - Levetireacetam made me feel drunk feeling and I had to be careful just walking around my homes and steps.
  • Psychosis, weight loss and topamax (1 response)
    I had a brain hemorrhage in my occipital lobe. It left me with with a partial seizure disorder. The seizures would interrupt my ability to see. I was trying different anti-seizure medication and they all made me more tired and more depressed. My neurologist decided to try topamax. On topamax I began to feel more energetic and started losing weight. For the first time in years I woke up in the morning feeling zippy. I started feeling euphoric sometimes. I started to feel like I was glowing with life. I became so energetic I was like someone in a manic state. My temper got shorter and I began to hallucinate. I started to see angels and/or feel their presence. I live in a big city and there are a lot of people who are pretty mean here and I decided I wasn't going to let any of them push me around. I wasn't diplomatic anymore with anyone. Basically everyone thought I had gone crazy and I guess I had.
    My psychiatrist saw me and told my neurologist to "Get Her Off The Topamax!" After I stopped taking it and was more my normal tired self, my psychiatrist told me that I had been psychotic and that I had scared him. Unfortunately, after I stopped taking topamax I gained back the 30 pounds I had lost and none of my new clothes fit me. My doctors told me that they had never seen Topamax affect anyone the way it had affected me. They said it usually makes people more sedated. Hopefully, sharing my experience with Topamax will be helpful to someone.
  • Eczema and birth control-microgestin
    I started getting eczema over the last year and recently decided it may be from the birth control as well, which I started taking @ 2 months before I got the eczema and skin started breaking out...weight gain, etc. I am on singulair, westcort cream, moisture/kenalog, exederm cream, cerevue wash, cetaphil moisturizer, and started using the black soap which is apparently helping. I started a vegetarian diet and eat mainly the same foods daily to monitor anything for allergies. I stopped taking the pill 3 days ago and I am optimistic. I am hoping others have had positive experiences.

More reviews for: Fentanyl, Topiramate

Comments from related studies:

  • From this study (1 year ago):

  • Have constant pain in knees, feet, toes, hands, arms, neck and back. Cannot sleep because I wake up constantly with shooting pain in neck, feet, knees, including tingles and numbness. Left side is worse; includes some drooling and paralysis at times. History of colitis and recent IPIN neiplasms found in pancreas head, neck and tail with dilated bile ducts as well as dilated pancreatic ducts and swelling of gallbladder. Constant nausea, off/on vomiting, major pain in neck and back, as well as abdomen which has included constant pain in upper right and left rib cage area. Knee pain has increased dramatically, especially while sleeping (??). Migraine history severe; hospitalized many times and is constant. Hx of anemias, malnutrition, malabsorption, fecal incontinence, low mono#, low eosinophil, high Granulocyte and Gran %, low Vit C, Low Vit B6, Low Lymphycites, High Baso%, High Baso#, Low WBC, Low Transferrin, High Cardio CRP, Positive ANA, High GGT, abnormal fecal fat, hypoalbuminemia, low calcium (always), low anion gap, low protein...many labs always abnormal, could go on...always fatigued and in pain.

    Reply

Complete drug side effects:

On eHealthMe, Fentanyl (fentanyl citrate) is often used to treat pain. Topiramate (topiramate) is often used to treat migraine. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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