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Review: taking Amoxicillin and Flagyl together

Summary: drug interactions are reported among people who take Amoxicillin and Flagyl together.

This review analyzes the effectiveness and drug interactions between Amoxicillin and Flagyl. It is created by eHealthMe based on reports of 1,355 people who take the same drugs from FDA and social media, and is updated regularly.





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What are the drugs

Amoxicillin has active ingredients of amoxicillin. It is often used in infection. (latest outcomes from 24,185 Amoxicillin users)

Flagyl has active ingredients of metronidazole. It is often used in vaginitis bacterial. (latest outcomes from 10,488 Flagyl users)

On Feb, 17, 2015: 1,355 people who take Amoxicillin, Flagyl are studied

Amoxicillin, Flagyl outcomes

Drug combinations in study:
- Amoxicillin (amoxicillin)
- Flagyl (metronidazole)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Amoxicillin is effective0.00%
(0 of 15 people)
(2 of 3 people)
(1 of 1 people)
(0 of 1 people)
Flagyl is effective0.00%
(0 of 15 people)
(1 of 2 people)
(1 of 1 people)
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
VomitingCytolytic HepatitisTirednessGallbladder DisorderAnxietyObesityn/aPain
NauseaOral DisorderStomach PainCholecystitisAbdominal Pain UpperBreathing Difficulty - Lying DownAnxiety
Abdominal PainMouth HaemorrhageUpset StomachPainEmotional DistressNeck, Shoulder And Arm SyndromeInjury
DiarrhoeaPainDizziness PosturalCholelithiasisGeneral Physical Health DeteriorationFrequent Or Urgent UrinationOsteonecrosis Of Jaw
HypertensionPurulent DischargeArrhythmiaDepressionFatigueArthralgia
DizzinessMetastases To LiverSyncopeInjuryChest PainAnaemia
Organising PneumoniaInfectionElectrolyte ImbalanceCholelithiasisNauseaNausea
HeadacheBone DisorderSupraventricular TachycardiaStressDisturbance In AttentionFatigue
Oedema PeripheralAbscess RuptureAbdominal PainDiarrhoeaPain - JointsDiarrhoea
Abdominal Pain UpperDeformityHeart Rate IrregularGastroenteritisDepressionBack Pain

Drug effectiveness by gender :

Amoxicillin is effective21.43%
(3 of 14 people)
(0 of 6 people)
Flagyl is effective15.38%
(2 of 13 people)
(0 of 6 people)

Most common drug interactions by gender * :

Osteonecrosis Of JawInjury
Pain In JawWeight Decreased
Back PainBone Disorder

Drug effectiveness by age :

Amoxicillin is effectiven/an/an/a0.00%
(0 of 4 people)
(0 of 4 people)
(0 of 4 people)
(3 of 21 people)
(0 of 4 people)
Flagyl is effectiven/an/an/a0.00%
(0 of 4 people)
(0 of 3 people)
(0 of 4 people)
(2 of 21 people)
(0 of 4 people)

Most common drug interactions by age * :

Neonatal Respiratory Distress SyndromePyrexiaCrohn's DiseaseNauseaAbdominal PainPainAnxietyPain
Maternal Drugs Affecting FoetusChronic SinusitisPainVomitingBack PainAnxietyPainAnxiety
Premature BabyConjunctivitisAnxietyInjuryCholelithiasisBone DisorderInjuryOsteonecrosis Of Jaw
Intraventricular Haemorrhage NosCoughCholecystitis ChronicPainNauseaGeneral Physical Health DeteriorationAnaemiaDiarrhoea
Necrotising Enterocolitis NeonatalAttention Deficit/hyperactivity DisorderHeadacheAbdominal Pain UpperPainDecreased InterestArthralgiaInjury
HypertriglyceridaemiaB-cell LymphomaVomitingAbdominal PainDiarrhoeaFatigueBack PainArthralgia
RestlessnessDepressionMelanocytic NaevusCholecystitis ChronicHeadacheHeadacheIntervertebral Disc ProtrusionBone Disorder
Foetal Growth RetardationEar InfectionLarge Intestine PerforationCholelithiasisDyspnoeaArthralgiaTooth ExtractionPain In Jaw
Neutropenia NeonatalToe WalkingAbscess IntestinalDyspnoeaAnxietyAnaemiaOsteonecrosis Of JawSpinal Osteoarthritis
Weight Gain PoorUpper Respiratory Tract InfectionCholelithiasisInsomniaDeep Vein ThrombosisPyrexiaOsteoarthritisHypoaesthesia

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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Do you take Amoxicillin and Flagyl?

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- support group for people who take Amoxicillin and Flagyl
- support group for people who take Amoxicillin
- support group for people who take Flagyl

Can you answer these questions (Ask a question):

More questions for: Amoxicillin, Flagyl

You may be interested at these reviews (Write a review):

  • Cdifficile treatment
    I had drug (cipro) induced cdifficile for three and a half years and was hospitalized 3 times and went through absolute hell until my Dr. finally agreed to do a fecal transplant. Even then the first transfer done via a lower bowel infusion didnt work. Two weeks after the first one he did a full colonoscopy transfer going up as high as my appendix and that one worked immediatly and I have had no furthur bowel problems, no diarrea at all and its' now been well over a year. I took every type of cdiff drug imaginable prior to that. I had to stay on Vancomyicin all the time or I would be spending all my time going back and forth to the john 20 or 30 times a day. I was so ill that I could bearly keep my head up. I couldnt eat without an urgent bathroom trip. I had to wear Depends all the time, my skin was raw and sore from constant wiping. I was given Tinture of Morphine to slow me down. That helped some. My veins collapsed from all the test shots and from the many pints of saline to keep me hydrated. My heart stopped from a lowering of my potassium level and I had to get a pacemaker to control my heart rate. I spent a fortune on the drugs,some costing as much as $1200.00 a month, more than I make working and working was rough. I would have to go to the restroom so often and I work outside where there were frequently no facilities. I would have to bring a complete change of clothes and a disinfecting kit with me to cleanup the restroom. I washed my hands raw. You cant leave that for someone else or they might get sick too as it is highly infectious. Hospitals are not that meticulous either. I once had to go to a Long Island Hospital that failed the precautions test miserably. They assigned me to a room with another patient whose family wanted to eat their meals in our shared room and then use the bathroom. I pitched a fit on them and told them no way were they going to eat in that room or use the bathroom. I can't imagine what that hospital was thinking. Anyway you get the idea....3 years of expensive treatment and all I needed was some healthy donor poop and someone willing to mix it up in a blender and put it in syringe and put it up the wassoo and I was done. Dont let them give you all the expensive treatment if you have a resistant case of cdiff, insist on the fecal transplant right off, you will be very glad you did. The donor should be someone in your family, preferably someone young with lots of good flora for digestion. Someone without other gut problems...they need to test them too. Bring it in the afternoon before and Bingo,you will be back on track the next day. I am open to answer questions or be tested orhelp with anything else you might want to know, just ask me.
  • Tingling feet and hands
    I have used flagyl 3 times and after stopping the use of this medication my feet and hands have became so tingly and itchy That its becoming unbearable.
  • Drug interractions savella. amoxicillin
    Sudden ache, pain and neuropathy in right hand and wrist within 8 hours of sterting Amoxicillin.
  • Lupus induced by amoxicillin (1 response)
    Was given Amoxicillin for Strep Throat and on day 10 I noticed a rash starting on my torso and began to feel ill, as if I had the flu. Went to emerg and got sent home with Benadryl. Woke up the next morning to the rash getting worse and an overall feeling of fatigue. Went to emerg again and this time had blood taken and the results showed an extreme rise in my white blood cells and by then, I had a fever. I was airlifted to another hospital where they did tests, but really had no idea what was wrong. I discharged myself with a script for corticosteroids and by then my joints began to stiffen, to a point of barely being able to walk and the pain was excruciating! I had to be cared for by my husband and struggled to lift my tea cup, or get out of bed. This lasted for about a month and then gradually began to subside. The doctors never did have answers for any of it. They chalked it up to an allergy to Amoxicillin. One mentioned "Steven Johnson Syndrome".
  • Amoxycillin and ear popping.
    I'm 30. I have otitis externa, but have never suffered with ear popping as a symptom. I had a flare up 2 wks before being prescribed this drug. I took a spay abx treatment which caused severe pain in my ears, so stopped taking that 5 days into the 7 day course. 4-5 days into my amoxicillin treatment for a uti, and my ears are popping. I have no known other medical problems, and am on no other meds.

More reviews for: Amoxicillin, Flagyl

Comments from related studies:

  • From this study (1 year ago):

  • Tooth was extracted


  • From this study (1 year ago):

  • It is too many symptoms to list. The mentioned are the symptoms I have right now.


  • From this study (1 year ago):

  • I had pleurisy about 1 year ago. Suddently got pain in my left chest, left arm and in my neck. Applied pressure to my artery in my neck which helped with the pain. Today the pain is moderate and not as severe. The symptoms are very different to when I had pleurisy before. I have recently been diagnosed with H Pylori infection and was treated for 10 days with 2 different anitbiotics (Ampycillin and Flagyl)


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Complete drug side effects:

On eHealthMe, Amoxicillin (amoxicillin) is often used to treat infection. Flagyl (metronidazole) is often used to treat vaginitis bacterial. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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