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Review: taking Flexeril and Ativan together

Summary: drug interactions are reported among people who take Flexeril and Ativan together.

This review analyzes the effectiveness and drug interactions between Flexeril and Ativan. It is created by eHealthMe based on reports of 2,098 people who take the same drugs from FDA and social media, and is updated regularly.


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On Mar, 28, 2015: 2,098 people who take Flexeril, Ativan are studied

Flexeril, Ativan outcomes

Drug combinations in study:
- Flexeril (cyclobenzaprine hydrochloride)
- Ativan (lorazepam)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Flexeril is effective5.00%
(1 of 20 people)
(5 of 16 people)
(0 of 9 people)
(1 of 8 people)
(6 of 13 people)
(0 of 3 people)
(5 of 8 people)
(0 of 2 people)
Ativan is effective26.67%
(4 of 15 people)
(3 of 17 people)
(2 of 10 people)
(5 of 14 people)
(3 of 12 people)
(6 of 10 people)
(4 of 7 people)
(0 of 2 people)

Drug effectiveness by gender :

Flexeril is effective26.67%
(16 of 60 people)
(2 of 19 people)
Ativan is effective34.33%
(23 of 67 people)
(4 of 20 people)

Drug effectiveness by age :

Flexeril is effectiven/an/an/a9.09%
(2 of 22 people)
(5 of 47 people)
(6 of 63 people)
(3 of 56 people)
(2 of 11 people)
Ativan is effectiven/an/an/a17.39%
(4 of 23 people)
(9 of 48 people)
(8 of 65 people)
(4 of 59 people)
(2 of 12 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Confusional StatePulmonary HaemorrhageDeep Vein ThrombosisAnxietyGastrointestinal DisorderDepressionAnxietyPain
DeliriumHaematemesisDepressionMental DisorderEmotional DistressAbnormal BehaviourDepressionAnxiety
DepressionCardiac ArrestPulmonary EmbolismDepressionCoronary Artery DiseaseSuicide AttemptTinnitusNausea
Abnormal BehaviourPanic AttackIntentional OverdoseSuicide AttemptCirculatory CollapseSuicidal IdeationAbnormal BehaviourDepression
Suicide AttemptDizzinessCompleted SuicideCompleted SuicideMigraineAnxietyMemory ImpairmentBack Pain
Unresponsive To StimuliMuscle SpasmsSuicide AttemptPainMyocardial InfarctionChronic DepressionAggressionFatigue
AnxietyCongenital Cystic Kidney DiseaseAnxietyIntentional OverdoseDyspnoea ExertionalAnxiety DisorderRecurring Skin BoilsHeadache
Respiratory FailureShortness Of BreathMental DisorderVision BlurredAngiopathyHenoch-schonlein PurpuraParanoiaDyspnoea
AgitationSwallowing DifficultyAbdominal Pain UpperDizzinessStress SymptomsViolence-related SymptomAgitationInsomnia
Memory ImpairmentAdhdEmbolic StrokeAngerAnxietyShort-term Memory LossHair LossArthralgia

Most common drug interactions by gender * :

HeadacheBack Pain
Back PainInsomnia

Most common drug interactions by age * :

Congenital Cystic Kidney Diseasen/aThrombosisAnxietyDepressionPainPainAnxiety
Diabetes MellitusAlanine Aminotransferase IncreasedVomitingAnxietyAnxietyAnxietyPain
RhabdomyolysisGallbladder DisorderInsomniaNauseaNauseaNauseaNausea
CholecystitisNauseaPainChest PainFatigueBack Pain
Myocardial InfarctionBack PainHypertensionDyspnoeaDepressionDyspnoea
Abdominal PainPainAstheniaDepressionBack PainDiarrhoea
Superior Sagittal Sinus ThrombosisBronchitisDyspnoeaBack PainDizzinessVomiting
Cerebrovascular AccidentHeadacheBronchitisArthralgiaArthralgiaWeight Decreased

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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Do you take Flexeril and Ativan?




You are not alone! Join a related support group:
- support group for people who take Ativan
- support group for people who take Flexeril

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Flexeril (cyclobenzaprine hydrochloride) is often used to treat muscle spasms. Ativan (lorazepam) is often used to treat stress and anxiety. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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