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Review: Flexeril and Clonazepam

This review analyzes the effectiveness and drug interactions between Flexeril and Clonazepam. It is created by eHealthMe based on reports of 2,062 people who take the same drugs from FDA and social media, and is updated regularly.

Get connected: join a mobile support group for people who take Flexeril and Clonazepam >>>

What are the drugs

Flexeril (latest outcomes from 16,427 users) has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms.

Clonazepam (latest outcomes from 41,218 users) has active ingredients of clonazepam. It is often used in stress and anxiety.

On Sep, 16, 2014: 2,062 people who take Flexeril, Clonazepam are studied

Flexeril, Clonazepam outcomes

Drug combinations in study:
- Flexeril (cyclobenzaprine hydrochloride)
- Clonazepam (clonazepam)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Flexeril is effective32.00%
(8 of 25 people)
(5 of 16 people)
(3 of 13 people)
(5 of 21 people)
(4 of 21 people)
(4 of 14 people)
(2 of 9 people)
Clonazepam is effective50.00%
(2 of 4 people)
(9 of 15 people)
(7 of 19 people)
(13 of 25 people)
(14 of 28 people)
(10 of 17 people)
(8 of 16 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
HeadachePainNausea In The Morning - FemalesPeripheral IschaemiaType 2 Diabetes MellitusPainHigh Blood PressureAnxiety
DepressionEmotional DistressEjection Fraction DecreasedCyanosisMicroalbuminuriaDepressionChest PainDepression
FatigueFearArterial Thrombosis LimbPainGallbladder DisorderEmotional DistressJoint StiffnessNausea
Memory ImpairmentRaDyspnoeaEmotional DistressDepressionPeripheral IschaemiaDermatitis AllergicHeadache
ParaesthesiaImpulse-control DisorderSickle Cell Anaemia With CrisisArterial ThrombosisDiabetic NeuropathyCyanosisSleep Disorder Due To General Medical Condition, Insomnia TypeBack Pain
Pathological GamblingJoint PainPulmonary CongestionDrug HypersensitivityDiabetes Mellitus Inadequate ControlCholecystitis ChronicIncontinenceDyspnoea
Suicide AttemptHeadache - Migraine With AuraVentricular TachyarrhythmiaItchingFatiguePancreatitisGallbladder InjuryDizziness
NauseaDry SkinMuscle OedemaAnxiety DisorderAnxietySphincter Of Oddi DysfunctionHypertensionFatigue
MalaiseLumbar Disc LesionHaemoglobin DecreasedFatigueSphincter Of Oddi DysfunctionSuicide AttemptDecreased AppetiteArthralgia

Drug effectiveness by gender :

Flexeril is effective23.96%
(23 of 96 people)
(8 of 23 people)
Clonazepam is effective49.50%
(50 of 101 people)
(13 of 23 people)

Most common drug interactions by gender * :

Back PainNausea
FatigueBack Pain
DyspnoeaChest Pain

Drug effectiveness by age :

Flexeril is effectiven/an/a100.00%
(1 of 1 people)
(5 of 19 people)
(12 of 86 people)
(3 of 59 people)
(9 of 67 people)
(1 of 13 people)
Clonazepam is effectiven/an/a50.00%
(1 of 2 people)
(7 of 20 people)
(22 of 89 people)
(14 of 63 people)
(14 of 67 people)
(5 of 13 people)

Most common drug interactions by age * :

Diabetes Mellitusn/aPainNauseaDepressionDepressionPainPain
Type 2 Diabetes MellitusPancreatitisInsomniaHeadachePainHeadachePain In Extremity
ObesityCholecystitis ChronicBronchitisPainAnxietyBack PainAnxiety
PancreatitisSphincter Of Oddi DysfunctionSinusitisAnxietyNauseaNauseaBack Pain
GastritisGallbladder DisorderPainDyspnoeaChest PainAnxietyArthralgia
Blood Cholesterol IncreasedAccidental DeathUpper Respiratory Tract InfectionNauseaFatigueDepressionHypoaesthesia
Multiple Drug OverdoseVomitingHypertensionWeight IncreasedDyspnoeaAsthenia
PyrexiaHeadacheBack PainBack PainHypoaesthesiaTooth Fracture
ArthralgiaAnxietyPain In ExtremityDizzinessDrug IneffectiveDyspnoea

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Flexeril and Clonazepam?

Comments from related studies:

  • From this study (3 months ago):

  • I had two unexplained broken bones within a one year period.
    Weak urine stream with intermittent breaks.
    High potassium level readings. First: 6.2 Second 5.2
    When diagnosed at ER with esophagitis was also suspected to have peptic ulcers due to stress.


  • From this study (7 months ago):

  • My pain is both from Endometriosis and Fibromyalgia. I have Periodic Limb Movement Disorder and RLS.


  • From this study (9 months ago):

  • It appears it is at its worse directly after a very heavy period.


Post a new comment    OR    Read more comments

Can you answer these questions (what is this?):

  • I cannot get a direct answer from any of my drs.,is my sciatic pain caused by my interstitail cystitus?
    I have had interstitail cystitus for almost four years now.I have been on every kind of drug,other than pain pills.I will not take them,I don't believe in them they only mask the problem and cause addiction.of course,just my belief.I have had d.s.m.o. repetitively for first year and a half twice a w ...

  • Does klonopin counteract phentermine?
    does klonopin counteract phentermine? i have taken phentermine before while not taking any other medications and it really worked for me but not its not working and i think my klonopin is counteracting it.

  • What is the current treatment for larangospasm?
    For two years I have been fighting with larangospasm. I have been hospitalized twice and treated with prednisone as well as nebulizers with albuterol. I had botox injections into my vocal cords last July 2013 and have a straw hanging around my neck for straw breathing. The last "attack" lasted one ...

More questions for: Clonazepam, Flexeril

You may be interested at these reviews (what is this?):

  • Sepsis hallucinations misdiagnosed
    I was admitted to the hospital at 10 p.m., with a total bowel blockage caused by scar-tissue adhesions. I had first gone to the ER at 3 a.m. that morning, but the ER doc misdiagnosed my condition as constipation. I was in extreme pain and also too weak to tell my husband when he first came home t ...

  • I wish i had never taken ambien
    Ambien was prescribed after my sleep study showed severe sleep latency and awakening. In the five hours I slept I woke 85 times and had only 5 minutes of deep sleep. However, the doctors couldn't make a recommendation because they could detect no cause for the poor sleep pattern. My doctor offered A ...

  • Psychosis, weight loss and topamax
    I had a brain hemorrhage in my occipital lobe. It left me with with a partial seizure disorder. The seizures would interrupt my ability to see. I was trying different anti-seizure medication and they all made me more tired and more depressed. My neurologist decided to try topamax. On topamax I ...

More reviews for: Clonazepam, Flexeril

Complete drug side effects:

On eHealthMe, Flexeril (cyclobenzaprine hydrochloride) is often used to treat muscle spasms. Clonazepam (clonazepam) is often used to treat stress and anxiety. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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