Review: taking Flexeril and Clonazepam together
Summary: drug interactions are reported among people who take Flexeril and Clonazepam together.
This review analyzes the effectiveness and drug interactions between Flexeril and Clonazepam. It is created by eHealthMe based on reports of 2,069 people who take the same drugs from FDA and social media, and is updated regularly.
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Flexeril has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms. (latest outcomes from 16,452 Flexeril users) Clonazepam has active ingredients of clonazepam. It is often used in stress and anxiety. (latest outcomes from 41,315 Clonazepam users)
What are the drugs
Flexeril has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms. (latest outcomes from 16,452 Flexeril users)
Clonazepam has active ingredients of clonazepam. It is often used in stress and anxiety. (latest outcomes from 41,315 Clonazepam users)
On Jan, 27, 2015: 2,069 people who take Flexeril, Clonazepam are studied
Drug combinations in study:
- Flexeril (cyclobenzaprine hydrochloride)
- Clonazepam (clonazepam)
Drug effectiveness over time :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years||not specified|
|Flexeril is effective||32.00%|
(8 of 25 people)
(5 of 17 people)
(3 of 13 people)
(5 of 21 people)
(5 of 22 people)
(4 of 14 people)
(2 of 10 people)
|Clonazepam is effective||50.00%|
(2 of 4 people)
(10 of 16 people)
(7 of 19 people)
(13 of 25 people)
(15 of 29 people)
(11 of 18 people)
(8 of 17 people)
Most common drug interactions over time * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years||not specified|
|Headache||Pain||Nausea In The Morning - Females||Peripheral Ischaemia||Type 2 Diabetes Mellitus||Pain||High Blood Pressure||Anxiety|
|Depression||Emotional Distress||Ejection Fraction Decreased||Cyanosis||Diabetes Mellitus Inadequate Control||Depression||Sleep Disorder Due To General Medical Condition, Insomnia Type||Depression|
|Fatigue||Anxiety||Arterial Thrombosis Limb||Pain||Depression||Emotional Distress||Dermatitis Allergic||Nausea|
|Memory Impairment||Ra||Dyspnoea||Emotional Distress||Diabetic Neuropathy||Peripheral Ischaemia||Chest Pain||Headache|
|Paraesthesia||Impulse-control Disorder||Sickle Cell Anaemia With Crisis||Arterial Thrombosis||Gallbladder Disorder||Cyanosis||Incontinence||Back Pain|
|Pathological Gambling||Joint Pain||Pulmonary Congestion||Drug Hypersensitivity||Microalbuminuria||Cholecystitis Chronic||Decreased Appetite||Dyspnoea|
|Suicide Attempt||Headache - Migraine With Aura||Ventricular Tachyarrhythmia||Itching||Anxiety||Pancreatitis||Impaired Gastric Emptying||Dizziness|
|Nausea||Dry Skin||Muscle Oedema||Anxiety Disorder||Sphincter Of Oddi Dysfunction||Sphincter Of Oddi Dysfunction||Gallbladder Injury||Fatigue|
|Malaise||Spinal Cord Injury Cauda Equina||Haemoglobin Decreased||Fatigue||Fatigue||Suicide Attempt||Hypertension||Arthralgia|
Drug effectiveness by gender :
|Flexeril is effective||24.24%|
(24 of 99 people)
(8 of 23 people)
|Clonazepam is effective||50.48%|
(53 of 105 people)
(13 of 23 people)
Most common drug interactions by gender * :
Drug effectiveness by age :
|Flexeril is effective||n/a||n/a||100.00%|
(1 of 1 people)
(5 of 19 people)
(13 of 87 people)
(3 of 61 people)
(9 of 67 people)
(1 of 13 people)
|Clonazepam is effective||n/a||n/a||50.00%|
(1 of 2 people)
(7 of 20 people)
(23 of 90 people)
(15 of 65 people)
(15 of 68 people)
(5 of 13 people)
Most common drug interactions by age * :
|Type 2 Diabetes Mellitus||Pancreatitis||Insomnia||Headache||Pain||Headache||Pain In Extremity|
|Obesity||Cholecystitis Chronic||Bronchitis||Pain||Anxiety||Back Pain||Anxiety|
|Pancreatitis||Sphincter Of Oddi Dysfunction||Sinusitis||Anxiety||Nausea||Nausea||Back Pain|
|Gastritis||Gallbladder Disorder||Pain||Dyspnoea||Chest Pain||Anxiety||Arthralgia|
|Blood Cholesterol Increased||Accidental Death||Upper Respiratory Tract Infection||Nausea||Fatigue||Depression||Hypoaesthesia|
|Multiple Drug Overdose||Vomiting||Hypertension||Arthralgia||Hypoaesthesia||Asthenia|
|Pyrexia||Headache||Bronchitis||Back Pain||Dyspnoea||Tooth Fracture|
|Arthralgia||Anxiety||Pain In Extremity||Dizziness||Drug Ineffective||Dyspnoea|
* Some reports may have incomplete information.
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- support group for people who take Flexeril and Clonazepam
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- support group for people who take Flexeril
Can you answer these questions (Ask a question):
- Does clonazapam cause tinnitus or ringing in the ears?
Patient fell a year ago and injured her neck and broke a bone in her arm. Has had severe pain in her neck. Getting acupuncture frequently. Recently tried to change medication from Valium to Clonazepam, and developed severe tinnitus. She said she only missed two days of Valium. She also says she has skipped days without taking valium and never had a problem. She says Clonazepam caused the tinnitus. I can't find anything that states a side effect of clonazepam is tinnitus.
- Can you stop trileptal cold turkey?
I ran outta my Trileptal, the last time I took it was in the hospital on Saturday I was there for 2 days and I was normally taking 300mg 2x daily and the hospital gave me 600mg 4x on Saturday and the day before I took the one 300mg I had left in the morning. Since the hospital I have not had any Trileptal to be able to take because they didn't send me home with any because I'm from another State and I'm not sure if that's why but I should have my medicine tomorrow but I feel horrible and I just wanna know if physically I will be alright? Thank you so much and would appreciate a quick responce.
- I take klonopin and diltiazem (calcium channel blocker blood pressure medicine) and am concerned about side effects. my accupuncturist recommends the ashwagandha. anyone have any issues with this?
I take these prescription medications but have been going to an accupuncturist since 2012. I have trouble sleeping at night without my clonazepam and take naps during the day and am having trouble losing weight. She thinks that my adrenal glands may be fatigued and told me to try something called Adrenal Response which contains Sensoril Ashwagandha. When I looked up Ashwaganda it said that it could interact with the Clonazepam or Klonopin and also with High blood pressure medication. I am a little concerned. I mentioned this to her and she said they both are metabolized by the liver and it should be ok to take it, just to take it an hour or more after I take the Clonazepam. Has anyone had any issues with interactions with their prescribed meds while taking Ashwagandha? I don't want to have to monitor my blood pressure because my blood pressure medication works good for me. Any help would be appreciated because I want to try it but I am a little scared too. Thanks, Crystal
- Can i take cialis and klonopin
I've been taking klonopin and it's making it hard for me to have an erection. Can I take cialis while on klonopin?
- I had bladder cancer and my doctor put me on metformin should i get off this
I do not want to take this metformin if it may cause my bladder cancer to come badk
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Neuropathic pain debuted when I was 24, now I'm 50. Received diagnosed with Ehler-Danlos syndrome (EDS), joint hypermobility type, when I was 35 years old. So it can take some time to get a diagnose. And as EDS-patient I do not belong to any clinic. Orthopedics says that EDS is not orthopedic, rheumatology says that EDS is not an autoimmune disease, GPs say that EDS is too difficult, and so on. Sooner or later we all end up at Psychiatry, even if we are not depressed.
The first kind of pain I got when I was 24 came from low back, but I experienced as pelvic pain and leg pain. It was clearly a neuropathic pain, but it took years to find out. Later it was treated by a pain clinic with cortisone around the genitofemoral nerves (both sides). Since this treatment didn't result in lasting freedom from pain, the pain clinic started to give me RF (radio frequency) treatment. This made the pain disappeared after one year, and I was 80% free from it between 2002 and 2014, 12 years. The pain doctors said pain could return after 10 years.
The other kind of neuropathic pain started 2003 with intense stomach pain. During 6 months I could hardly eat nothing due to nausea and vomiting. After this 6 months, stomach pain changed to almost unbearable pain in upper back.
What happened 2003, and what all the doctors missed, was that the right lowest ribs slid up over the sternum. This rib dislocation is till there today, but now with a lot of cartilage formed around the rib where it is stuck in the lower end of the sternum. The dislocation is clearly visible on X-ray. This has greatly affected the thoracic spine. I have a scoliosis which I had not before 2003. And I still have severe pain in the thoracic spine.
It was initially treated with morphine daily, and later with Durogesic (fentanyl), but this didn't help much. 2005 I was hospitalized because I had too much pain to take care of myself and my hygiene. After some months the doctors started to give me clonazepam because the muscles along the spine was in a chronic seizures. Clonazepam helped, but I could still have a lot of pain in two vertebrae in the thoracic spine. It felt as if someone drilled into the vertebrae without anesthesia. After a few months, doctors also prescribed me methadone. Then the pain disappeared almost completely. Since 2006, I have eaten clonazepam and methadone every day, and I need to sleep in an armchair to not get more pain because of moving during sleep.
There are side effects. After 1,5 years with clonazepam and methadone I started to have panic attacks. Or rather one long panic attack which didn't stop before I got treatment with amitryptilin and pregabalin (Lyrica). These 2 medicines stopped the panic disorder completely after some hours, and the panic was then gone. Then I got side effects of these 2 medicines, amitryptilin & Lyrica, too. I gained a lot of weight (from 83 to 148 kg) and got much water (edema) in both my legs under the knees and in both feet. The feet could swallow to the double size. 2012 I stopped with amitryptilin and started to loose weight again (in Aug 2014 below 80 kg) and get less water in my legs. Today I eat as little medicines I can, but I have to take methadone, clonazepam and Lyrica every day, twice. If I try to take away one of these 3 medicines, I got pain problems at once. Lyrica is the most painful one to take away. In Sept-Dec 2013 I lowered Lyrica from 300 mg daily, to 150, then to 75 and finally 0 mg. The pain I had was extremely difficult to handle. It didn't help to take more methadone or anything else. I have checked on Internet and found that many people got pain from quitting with Lyrica. Most people start eating it again. So did I. But 2006 and 2007 it was enough to treat the pain with methadone and clonazepam, I got the Lyrica against anxiety not pain. But today I take Lyrica against pain.
Beside weight gain and leg edema, clonazepam and Lyrica significantly affect the sexual desire. And Lyrica alone makes it almost impossible to ejaculate. All four drugs together (clonazepam, methadone, amitryptiline and Lyrica), make one forget all about sex life. You don't even miss it. When I stopped with amitryptiline and lowered Lyrica (still taking clonazepam and methadone), I could suddenly easily get erections again, feel desire, but not getting orgasms. This is quite difficult to deal with.
The pain pattern is greatly affected, by pain and by the medicines. So is the mood. I get something which feels like heavy depression, especially if I take the medicines late that day. I should take a medicine like methadone 3 times a day, because the effects of the tablet lasts around 8 hours. But I take them every 12 hours, to have a low consumption in case doctors prescribe them too late (which happens, and then it's good to have a spouse going to the pharmacy buying them for you, because you have too much pain to go yourself).
Since methadone is also used for treating heroine addicts, medical staff treat you with disrespect when they see that it says "methadone" in your health record. I need to show a certificate that says that I deal with chronic neuropathic pain, that I never have had problems with drug addiction, to get normal respect.
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- Sepsis hallucinations misdiagnosed
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- I wish i had never taken ambien
Ambien was prescribed after my sleep study showed severe sleep latency and awakening. In the five hours I slept I woke 85 times and had only 5 minutes of deep sleep. However, the doctors couldn't make a recommendation because they could detect no cause for the poor sleep pattern. My doctor offered Ambien and since I had obviously needed the help sleeping I took it. For the next 10 years I suffered incredible depression. For example I remember laying in bed staring at the ceiling with tears rolling into my ears but I was too tired to wipe them away and realizing that I wanted to die so badly but there was no way I could have done anything about it. The worst effects were the loss of consciousness and the verbal abuse that I heaped on my husband and son. An example of each : I actually had sex with my husband that I could not remember amd hundreds of other actions and discussions. My husband started asking every morning what I remembered of the night before. He could usually tell when I was Ambien-awake (his name for it) he said my eyes would get glassy and my voice cadence would be off. Unfortunately my oldest son was going from infant to 8 years old at this time and any ifraction or even without provocation I would scream horrible things in his face. I don't remember much of it but what I do remember causes me enormous regret. He went from a happy and active toddler to a terrified amd anxious pre-teen. We are still working through the effects of this behavior. Finally, after a surprise pregnancy (see example above) My baby was placed in NICU and I stayed at the Ronald McDonald House and my son and husband visited when they could. Somehow my Ambien prescription was stopped and so I began going through withdrawal but I had no idea what was going on. My vision became so blurred thqt I couldn't identify items unless they were very large and then only by colors. When I visited my son those several days in the NICU I couldn't walk straight and would try to aim myself toward my goal until I hit a wall and I would correct course. These things didn't bother me at all but the nurses in the NICU were with me nearly the entire day because they were afraid I would have a stroke or who knew. Finally, after discussing these symptoms we decided to gradually stop the medication. Thankfully, i didn't have any withdrawal symptoms then. I did feel like an incredibly heavy and black blanket had been lifted away. Ever since I have had very little trouble with depression despite the continuation of sleep disturbance and pain. On a scale from one to 10 for depression with 10 being committing suicide I think my 10 years on the medicine was probably an 8.5 (I desperately wanted to die) and since stopping the medication I don't think it has gone above a 4 and is usually a 2 or 3. I will spend the rest of my life trying to repair the damage my verbal abuse caused my oldest son and my husband. For 10 years they lived in fear of my rages if I had a bad episode with Ambien.
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I have chronic fatigue syndrome, fibromyalgia, GERD, IBS, Bipolar 2, PTSD. High levels of anxiety and depression, hypomanic states at times. Hospitalization has been required multiple times to alter drugs. Abuse and overuse of drugs, mixing drugs has been ongoing for 9 weeks. Detox program starting.
I am a 48 yr old female diagnosed with PTSD, bipolar 2, BPD, histrionic suicidal idealation and a mess!!!
Things were going well in therapy and with my Dr. over the past 2 years on the above "cocktail" MINUS the Latuda and Lexapro.
I have had 3 very serious suicide attempts, all prior to the Tegretol /Prozac regime.
I do not want to change meds! Prior to the Tegretol, Klonopin , Lamictal , Prozac, Trazodone routine, I had made 3 very serious suicide attempts. The last leaving me with liver and kidney disease.
I've recently been left with two tragic yet situational on sets. So against my desire, I agreed to omit Prozac and replace with Lexapro and add Latuda, replacing Tegretol.
I have not been this unbalanced for YEARS! I know my triggers with suicide and believe that is the only reason I'm still alive. I HAD NOT THOUGHT ABOUT suicide for EIGHT YEARS!
Crying all the time, don't eat or sleep for sometimes, up to four days! I'm so tired, I just cry more from frustration of not being able to sleep.
I see my therapist tomorrow, but am on the "call" list for my Dr.
With the holidays among us, I do not nor do I think I can make it on these meds.
Can you PLEASE TELL ME if you know and I wasn't told, the, if any benefits will come forth? I know we are all different and I do trust my Md. Just not this time. Please, please help. Thank you.
I had two unexplained broken bones within a one year period.
Weak urine stream with intermittent breaks.
High potassium level readings. First: 6.2 Second 5.2
When diagnosed at ER with esophagitis was also suspected to have peptic ulcers due to stress.
Complete drug side effects:
On eHealthMe, Flexeril (cyclobenzaprine hydrochloride) is often used to treat muscle spasms. Clonazepam (clonazepam) is often used to treat stress and anxiety. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.
What is the drug used for and how effective is it:
- Flexeril is used in:
- Clonazepam is used in:
Other drugs that are used to treat the same conditions:
- Flexeril alternatives:
- Clonazepam alternatives:
NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
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