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Review: Flexeril and Doxycycline Hyclate





Summary: drug interactions are reported among people who take Flexeril and Doxycycline Hyclate together.

This review analyzes the effectiveness and drug interactions between Flexeril and Doxycycline Hyclate. It is created by eHealthMe based on reports of 338 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Flexeril and Doxycycline Hyclate >>>

What are the drugs

Flexeril has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms. (latest outcomes from Flexeril 16,445 users)

Doxycycline hyclate has active ingredients of doxycycline hyclate. It is often used in acne. (latest outcomes from Doxycycline hyclate 2,398 users)

On Dec, 1, 2014: 338 people who take Flexeril, Doxycycline Hyclate are studied

Flexeril, Doxycycline Hyclate outcomes

Drug combinations in study:
- Flexeril (cyclobenzaprine hydrochloride)
- Doxycycline Hyclate (doxycycline hyclate)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Flexeril is effective33.33%
(1 of 3 people)
0.00%
(0 of 1 people)
n/a0.00%
(0 of 1 people)
0.00%
(0 of 1 people)
66.67%
(2 of 3 people)
n/an/a
Doxycycline Hyclate is effective50.00%
(1 of 2 people)
0.00%
(0 of 1 people)
0.00%
(0 of 2 people)
n/a0.00%
(0 of 2 people)
n/an/an/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Cardiac FailureCholelithiasisn/aOedemaDepressionDeep Vein Thrombosisn/aPain
HypertensionCholecystitis ChronicMemory ImpairmentSuicide AttemptDyspnoeaFatigue
AngioedemaAbdominal Pain UpperPainParanoiaPain In ExtremityBack Pain
Impaired Gastric EmptyingSuicidal IdeationNightmareCellulitis StaphylococcalNausea
Renal FailureWeight IncreasedIrritabilityOedema PeripheralAnxiety
Multi-organ FailureJoint SwellingIntentional OverdosePulmonary EmbolismDyspnoea
Chest PainArthralgiaDaydreamingPainHypertension
CellulitisBack PainPoor Quality SleepDepressionDepression
Deep Vein ThrombosisCondition AggravatedAnxietyInjuryNeuropathy Peripheral
Pain - MusclesDepressionDeep Vein ThrombosisParanoiaPain In Extremity

Drug effectiveness by gender :

FemaleMale
Flexeril is effective42.86%
(3 of 7 people)
0.00%
(0 of 2 people)
Doxycycline Hyclate is effective0.00%
(0 of 5 people)
50.00%
(1 of 2 people)

Most common drug interactions by gender * :

FemaleMale
PainPain
FatigueDiarrhoea
NauseaPyrexia
AnxietyDizziness
Back PainAnaemia
DepressionMusculoskeletal Pain
DyspnoeaBack Pain
AstheniaHeadache
Oedema PeripheralAnxiety
ArthralgiaNeuropathy Peripheral

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Flexeril is effectiven/an/an/a0.00%
(0 of 2 people)
50.00%
(2 of 4 people)
10.00%
(1 of 10 people)
0.00%
(0 of 1 people)
n/a
Doxycycline Hyclate is effectiven/an/an/a0.00%
(0 of 1 people)
0.00%
(0 of 4 people)
0.00%
(0 of 2 people)
100.00%
(1 of 1 people)
n/a

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/an/aAnxietyCholelithiasisDyspnoeaDepressionAnxietyPain
Emotional DistressAbdominal Pain UpperFatigueNauseaPainOsteoarthritis
PainCholecystitis ChronicPainPainInsomniaPyrexia
Pregnancy On Oral ContraceptiveBiliary DyskinesiaEmotional DistressBack PainNauseaAnxiety
CholelithiasisNauseaHyperhidrosisArthralgiaOedema PeripheralAnaemia
Pre-eclampsiaGallbladder InjuryBack PainAnxietyFatigueDyspnoea
General Physical Health DeteriorationPulmonary ThrombosisAnxietyAlopeciaMyalgiaBack Pain
Cholecystitis ChronicChest PainNauseaFatigueDiarrhoeaWeight Decreased
InjuryPain In ExtremityMyalgiaMyalgiaDental CariesAsthenia
Pulmonary EmbolismAnhedoniaAstheniaNeuropathy PeripheralFatigue

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Flexeril and Doxycycline Hyclate?

You are not alone! Join a related mobile support group:
- support group for people who take Flexeril and Doxycycline Hyclate
- support group for people who take Doxycycline Hyclate
- support group for people who take Flexeril

Can you answer these questions (Ask a question):

  • Can nuvigil (vs adderall) be used simultaneously to help wean off 60mg/day of adderall? (1 answer)
    I have been on Adderall 30mg 2x daily for years!! I've had it lowered to 20mg, I've TRIED to go months without it (when not working) however I feel I've built up a tolerance level to the point that it's not as effective as it once was. My personal life has detoured WAY past anything an ADHD medication can possibly help as far as focusing on NEEDED tasks etc. I end up feeling wrapped up in what I'm doing at the moment that my anxiety increases due to all that I haven't been able to accomplish. I take various medications for various reasons, depression, anxiety, bulimia etc., and for the most part the doses have varied based on circumstances and current need at said time of prescription.. MY FAMILY HAS A HISTORY OF HEART DISEASE, And realizing that I'm already on the highest Adderall dosage scares me (and THEN as I think about it, it makes my heart race!). I've also noticed increased muscle spasms as well as extreme and intense pressure on my jaw (TMJ). MY QUESTION IS: does anyone have any experience LOWERING their Adderall dosage AND adding Nuvigil? The research I've done to date gives me impression that it could help balance out the more extreme effects of Adderall (60mg/day) but that the nuvigil would or could potentially help with the EXTREME exhaustion I feel as Adderall wears off. Some days I just crash, some days I sleep fine and others no matter how hard I tryyyy, I just CAN'T fall asleep, therefore making the next day worse! IDEALLY I'D LIKE TO BE MED FREE, right now I need them, but am hoping maybe I can speak with my doctor to lower Adderall and add Nuvigil to help wean me off the amphetamines as well as lower dosage intake. YES, a lot of the anxiety, sleeplessness and depression are related to current circumstances in my life, however, where I am is not where I want to be or where I'm headed.. Life is a journey, and all my meds have become a part of a journey I never thought I'd find myself taking. I don't want life/meds to define me, or create a me I no longer recognize, because scarily enough that seems to be a common pattern. As I overcome each and every daily obstacle, I also don't want to be "hooked" on my meds or needing "more" to wake up/sleep/function.. I'd like to work on finding a solution towards weaning off my meds NOW, and work my way off slowly, primarily the Adderall. I'm hoping by suggesting to my doctor and showing him my research he may agree (IF ITS EVEN A LOGICAL COMBO, CLEARLY IM NOT A DOCTOR) nuvigil could help me. I've already started taking less of my anti depressants, trazadone and xanax without discussing with doc because he is always busy.. My next appt I want to go in fully prepared with a plan and an overall goal to REDUCE my Adderall dose, but overall, I'm clueless!!! I have no idea what other meds other than nuvigil "could" potentially help if at all. I could be entirely wrong, Anyone with any experience using one vs other or both simultaneously, or anyone with constructive input, PLEASE COMMENT/SHARE!!
  • Why would i get copd since i never smoked?
    I have several autoimmune disorders, I was shocked to get the COPD diagnosis since I have never smoked but I had second hand smoke first 23 years of my life.
    My doctor said my Autoimmune Hepatitis and Primary Biliary Cholingitis set me up for COPD.
  • I have chladmydia in my eye,,doctor has given me a single dose 1 gram of azithromycin,,however im a carrier of hep c,,should i take this medicine
    I have gotten chladmydia bot genatally and its in my eye,,i have been a carrier of hep c for a long time,,my doctor has given me a single dose of azithromycin at 1 gram,,im afariad this may lead to liver failure,,anyone know
  • Is it safe to take effexor and ibuprophen?
    Have sinus infection which I'm taking doxycycline and ibuprophen for headache. I also take Venlafaxine for GAD. Is it okay to take Advil or acetaminophen while taking venlafaxine, not at the same time??
  • I cannot get a direct answer from any of my drs.,is my sciatic pain caused by my interstitail cystitus? (1 answer)
    I have had interstitail cystitus for almost four years now.I have been on every kind of drug,other than pain pills.I will not take them,I don't believe in them they only mask the problem and cause addiction.of course,just my belief.I have had d.s.m.o. repetitively for first year and a half twice a week.I have tried physical therapy .I have had five hydrodistention.I just recently had my first hydrodistention with botox injections.nothing has kept me out of pain .even when I am doing good I can only seem to reach a six in my pain level.my frequency average is and has been 30-40Times a day.I am,or,was a chef kitchen manager.could not perform and lost two jobs because of this disease.my flanks,my lower back ,my legs,my arms all ways in pain.pelvic pain is constant.I'd rather not go into further details way too personal.but this has taken my life.I am 35.I have led a fairly healthy life.I have no life now.I am seeking disability .Every Dr. I go to has a different option about the sciatic part of my problem some Dr.s are very sure and as a matter of fact about how it is in conjunction with I.c..others look at me like I'm nuts?why do I limp?why can't I get in and out of a car,or bend down and touch my toes,pick heavy stuff up.just to laugh at times hurts.this is my life ,I gotta wonder ,is there any one else out there going through the same symptoms and no relief?

More questions for: Doxycycline Hyclate, Flexeril

You may be interested at these reviews (Write a review):

  • My experience with lyme
    My final semester at college-

    Woke up to extreme inflammation in what was determined to be a portion of my trapezius on the left side length of my next. It was accompanied by severely swollen lymph nodes throughout my entire body. I went about my day with what to me was seemingly a bad neck cramp and oncoming cold. In the afternoon I decided to participate in Track practice and what occurred after I am unsure about in terms of its relation to me performing physically or an autoimmune response against my peripheral nervous system. The next morning I woke up the left side of my trapezius was completely dysfunctional from its attachment to my cranium all the way down to the mid point of my back. It was accompanied by inflammation and sore pain at the point where the next connects to the shoulder girdle. Over the course of the next 8 months I went undiagnosed with Lyme, having seen neurologists and orthopedics in an attempt to find a solution. Reflecting on the first three months, I experienced significant effects on my emotional stability and cognitive capability. I would have severe mood swings--rage, depression, excitement-- and I would have difficulty with memory and train of thought- all of which can be confirmed by multitude of classmates. By the 8 month mark I had began to feel mild joint pain, particularly in areas I had formerly injured in athletic activity (ankles, lower back). At this point, my accessory nerve had not regenerated in terms of the portion affecting my trapezius, didn't regain any lost muscle function. I saw my physician, who discovered the Lyme infection. I took doxycycline over the next 3 months and saw significant improvement in my trapezius, which was accompanied by a decrease in lymph node size, as proven by comparison of MRIs. My fatigue dissipated and my moods/cognition returned to normal. I've regained about 70% of the function I formerly had with my trapezius (as compared to 0% prior to treatment). I wanted to write this because I have yet to see a similar case, understand the ambiguity of Lyme disease and the array of conditions it causes.
  • I wish i had never taken ambien
    Ambien was prescribed after my sleep study showed severe sleep latency and awakening. In the five hours I slept I woke 85 times and had only 5 minutes of deep sleep. However, the doctors couldn't make a recommendation because they could detect no cause for the poor sleep pattern. My doctor offered Ambien and since I had obviously needed the help sleeping I took it. For the next 10 years I suffered incredible depression. For example I remember laying in bed staring at the ceiling with tears rolling into my ears but I was too tired to wipe them away and realizing that I wanted to die so badly but there was no way I could have done anything about it. The worst effects were the loss of consciousness and the verbal abuse that I heaped on my husband and son. An example of each : I actually had sex with my husband that I could not remember amd hundreds of other actions and discussions. My husband started asking every morning what I remembered of the night before. He could usually tell when I was Ambien-awake (his name for it) he said my eyes would get glassy and my voice cadence would be off. Unfortunately my oldest son was going from infant to 8 years old at this time and any ifraction or even without provocation I would scream horrible things in his face. I don't remember much of it but what I do remember causes me enormous regret. He went from a happy and active toddler to a terrified amd anxious pre-teen. We are still working through the effects of this behavior. Finally, after a surprise pregnancy (see example above) My baby was placed in NICU and I stayed at the Ronald McDonald House and my son and husband visited when they could. Somehow my Ambien prescription was stopped and so I began going through withdrawal but I had no idea what was going on. My vision became so blurred thqt I couldn't identify items unless they were very large and then only by colors. When I visited my son those several days in the NICU I couldn't walk straight and would try to aim myself toward my goal until I hit a wall and I would correct course. These things didn't bother me at all but the nurses in the NICU were with me nearly the entire day because they were afraid I would have a stroke or who knew. Finally, after discussing these symptoms we decided to gradually stop the medication. Thankfully, i didn't have any withdrawal symptoms then. I did feel like an incredibly heavy and black blanket had been lifted away. Ever since I have had very little trouble with depression despite the continuation of sleep disturbance and pain. On a scale from one to 10 for depression with 10 being committing suicide I think my 10 years on the medicine was probably an 8.5 (I desperately wanted to die) and since stopping the medication I don't think it has gone above a 4 and is usually a 2 or 3. I will spend the rest of my life trying to repair the damage my verbal abuse caused my oldest son and my husband. For 10 years they lived in fear of my rages if I had a bad episode with Ambien.
  • Symptons from taking doxycyclin
    I recently went in for a physical, everything was normal except my Creatinine levels. I had severe symptoms from burning hands/knuckles to feeling very tingly like cold needles. Also, burned very easily from sun even with 50 sun screen applied. Should I be worried about the Creatinine levels be abnormally high?
  • Doxycycline/severe sun reaction
    Was put on Doxycycline for an infection on the surface of my knee.Went to a football game in NC,SEPT.14TH,was in sun for maybe 3-4 hours.I have Virgilio but have been in sun many times with no such burn.Also used 45 sunblock!



    Went to doctor following Monday,because of concern for infection,she started a new antibiotic and healing began. I am two weeks now ,into the burn and have large scabbed areas and a continued red,burning skin!!
  • I got pneumonia while taking topamax, obvious correlation
    I do not take all the medicines above all the time but I am using an implanted pump giving me less than 2mg of dilaudid per day, 75 mg effexor daily and usually buspar. Dr prescribed topamax within 4 days I was hospitalized with Pneumonia, stayed a week came home a week had a clear chest x ray and the next week I got it again and was hospitalized 9 days that time. I knew I had been on the med but could not remember the side effect that made me come off previously until i started it again 2 days ago and woke today with Pneumonia again. Last time my pulmonologist said that the med in combination with the antidepressant which is all I take right now relaxes me too much and it paralyzes my choking reflex causing aspiration of saliva and ultimately waking up sick as the bacteria laced fluid goes crazy in the moist conditions of the lungs.

More reviews for: Doxycycline Hyclate, Flexeril

Complete drug side effects:

On eHealthMe, Flexeril (cyclobenzaprine hydrochloride) is often used to treat muscle spasms. Doxycycline Hyclate (doxycycline hyclate) is often used to treat acne. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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