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Review: taking Flexeril and Lyrica together

Summary: drug interactions are reported among people who take Flexeril and Lyrica together.

This review analyzes the effectiveness and drug interactions between Flexeril and Lyrica. It is created by eHealthMe based on reports of 1,715 people who take the same drugs from FDA and social media, and is updated regularly.

 

You are not alone: join a support group for people who take Flexeril and Lyrica >>>

On Mar, 28, 2015: 1,715 people who take Flexeril, Lyrica are studied

Flexeril, Lyrica outcomes

Drug combinations in study:
- Flexeril (cyclobenzaprine hydrochloride)
- Lyrica (pregabalin)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Flexeril is effective0.00%
(0 of 9 people)
8.33%
(1 of 12 people)
10.00%
(1 of 10 people)
27.27%
(3 of 11 people)
37.50%
(12 of 32 people)
21.43%
(3 of 14 people)
50.00%
(3 of 6 people)
50.00%
(1 of 2 people)
Lyrica is effective16.67%
(2 of 12 people)
20.83%
(5 of 24 people)
14.29%
(1 of 7 people)
33.33%
(6 of 18 people)
30.77%
(8 of 26 people)
44.44%
(4 of 9 people)
n/a0.00%
(0 of 1 people)

Drug effectiveness by gender :

FemaleMale
Flexeril is effective25.61%
(21 of 82 people)
21.43%
(3 of 14 people)
Lyrica is effective27.71%
(23 of 83 people)
21.43%
(3 of 14 people)

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Flexeril is effectiven/an/a100.00%
(1 of 1 people)
0.00%
(0 of 18 people)
16.67%
(9 of 54 people)
19.05%
(8 of 42 people)
5.97%
(4 of 67 people)
12.50%
(2 of 16 people)
Lyrica is effectiven/an/a0.00%
(0 of 1 people)
5.26%
(1 of 19 people)
18.18%
(10 of 55 people)
24.32%
(9 of 37 people)
5.88%
(4 of 68 people)
12.50%
(2 of 16 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
DizzinessAnxietyMulti-organ FailurePainDepressionIrritabilityMuscle Contractions InvoluntaryPain
Vision BlurredDepressionHyperhidrosisAnxietyPainDepressionDry MouthAnxiety
Drug IneffectiveDizzinessNeutropeniaDepressionAnxietyBlood Cholesterol IncreasedAnxiety AggravatedOedema Peripheral
SomnolencePainSeptic ShockDizzinessWeight DecreasedDaydreamingIrritable Bowel SyndromeNausea
NauseaDrug IneffectiveAnxietyInsomniaParanoiaErythemaPanic Disorder With AgoraphobiaFatigue
Dry MouthWeight IncreasedWeight DecreasedConstipationDiabetes MellitusBlood Thyroid Stimulating Hormone IncreasedStiffness In A JointBack Pain
Oedema PeripheralNervousnessAmnesiaNauseaWeight IncreasedHypertensionFrequent HeadachesDrug Ineffective
PainConfusional StateDyspepsiaCardiac DisorderHypoaesthesiaWeight IncreasedBody OverheatingWeight Increased
Weight DecreasedNauseaWithdrawal SyndromeTremorMulti-organ FailureOedema PeripheralMeniere's DiseaseHypoaesthesia
Memory ImpairmentHypersensitivityNauseaHeadacheNeutropeniaSleep DisorderDry Eyes AggravatedArthralgia

Most common drug interactions by gender * :

FemaleMale
PainPain
Oedema PeripheralAnxiety
AnxietyNeuropathy Peripheral
NauseaDrug Ineffective
FatigueDizziness
Weight IncreasedFatigue
Drug IneffectiveBack Pain
Back PainDyspnoea
OsteoarthritisConstipation
DyspnoeaHypoaesthesia

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Foetal Exposure During Pregnancyn/aConvulsionPain In ExtremityPainPainPainPain
DeathConversion DisorderPulmonary EmbolismWeight IncreasedDrug IneffectiveOedema PeripheralAnxiety
DisorientationChest PainDepressionMuscle SpasmsFatigueAnaemia
Hallucination, AuditoryHypoaesthesiaDyspnoeaArthralgiaAnxietyHypertension
PyrexiaInsomniaDizzinessSomnolenceOsteoarthritisOedema Peripheral
AstheniaPulmonary EmbolismAnxietyNauseaOsteoarthritis
BronchitisNauseaDepressionHypoaesthesiaNausea
Influenza Like IllnessAbdominal Pain UpperVomitingWeight IncreasedArthralgia
CholecystitisAnxietyDyspnoeaOsteoporosisBack Pain
Cardiac Failure CongestiveFeeling AbnormalMemory ImpairmentBone PainDizziness

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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- support group for people who take Flexeril
- support group for people who take Lyrica

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Flexeril (cyclobenzaprine hydrochloride) is often used to treat muscle spasms. Lyrica (pregabalin) is often used to treat fibromyalgia. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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