Review: Flexeril and Lyrica drug interactions
This review analyzes the interactions between Flexeril and Lyrica. It is created by eHealthMe based on 1,629 people who have drug interactions while taking the drugs. The review uses reports from FDA and social media, and is updated regularly.
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What are the drugs
Flexeril (latest outcomes from 16,348 users) has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms.
Lyrica (latest outcomes from 66,316 users) has active ingredients of pregabalin. It is often used in fibromyalgia.
On Mar, 2, 2014: 1,629 people who reported to have interactions when taking Flexeril, Lyrica are studied
Drug combinations in study:
- Flexeril (cyclobenzaprine hydrochloride)
- Lyrica (pregabalin)
Most common interactions experienced by people in the use of Flexeril, Lyrica:(click on each outcome to view in-depth analysis, incl. how people recovered)
|Interaction||Number of reports|
|Arthralgia (joint pain)||436|
|Dyspnoea (difficult or laboured respiration)||413|
|Fatigue (feeling of tiredness)||270|
|Nausea (feeling of having an urge to vomit)||254|
|Oedema Peripheral (superficial swelling)||252|
|Hypoaesthesia (reduced sense of touch or sensation)||217|
Most common interactions experienced by people in long term use of Flexeril, Lyrica:(click on each outcome to view in-depth analysis, incl. how people recovered)
|Interaction||Number of reports|
|Hypertension (high blood pressure)||18|
|Withdrawal Syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)||8|
How effective are the drugs:
|not at all||somewhat||moderate||high||very high|
Top conditions involved for these people * :
- Rheumatoid arthritis
Top co-used drugs for these people * :
* Approximation only. Some reports may have incomplete information.
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Complete drug side effects:
On eHealthMe, Flexeril (cyclobenzaprine hydrochloride) is often used to treat muscle spasms. Lyrica (pregabalin) is often used to treat fibromyalgia. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.
What is the drug used for and how effective is it:
- Flexeril is used in:
- Lyrica is used in:
Other drugs that are used to treat the same conditions:
- Flexeril alternatives:
- Lyrica alternatives:
Comments from related studies:
From this study (3 weeks ago):
From this study (2 months ago):
From this study (5 months ago):
I am suffering from severe mood swings and nervousness. Sometimes I am so mad I want to rip something apart, most of the time my poor husband catches the brunt of it. My headaches are coming back, but I really want to get rid of the crazy mood swings before I hurt myself or someone else when i lose my temper maybe in a car driving, I will fly into a rage over little things...Please help me with this.
What do I need to get OFF of OR ON...
Thank you, Carolyn
Diagnosed with non-diabetic small fiber neuropathy. Also moderate to severe stenosis lumbar spine. Cyst in lumbar spine. Also fusion c3-c4 and c6-c7 02 2013 with mylemacia.
Constipation managed with high fiber diet until 08 2013. Then chronic constipation, treated with high volume enema, then Miralax pm, sennacot pm and am, colase am and Relistor injection every other day.
Night sweats constantly and once I get hot and start sweating I can't cool down. I just sweat more and more until I do something like blast a fan on me for a long time and I have to keep my a/c down really low. Any activity causes the sweating to start which begins at my head, face and neck and down my back.
Can you answer these questions (what is this?):
- By InsomniaRampant: Can a person use trazodone and dexamethasone?
I have only been on this for one day started like a moron at 8pm and ive been on it once before on a high dose but this is like 1mg bid for 7 days and i had a recent discovery im allergic to oxycontin as i would randomly pass out or be awake for days tripping, havent ever been on it before. Only rea ...
- By Bob: Are there any reports of extreme dry mouth?
Since having an aortic valve replacement via TAVR (newer technique)I have had various medications added to my schedule. For the last several months I seem to have a very dry mouth problem. I have given you a few that I am taking at the present time that I thought might have some effect on my dryne ...
- By clmason: Can i take 10mg wellbutrin and 15mg cyclobenziprin
Wellbutrin make lose weight and give me head aches so I take cyclobenzaprin for weight gain and head aches
You may be interested at these reviews (what is this?):
- By lisabug: Lyrica caused my kidneys to shut down
I was on Lyrica for 6 weeks and it almost killed me. I was so weak at the end that my daughter had to help me get out of bed go to the bathroom. I gained 22 lbs in 10 days. I gained over 40 lbs in 6 weeks. My ankles and feet were so swollen that the skin was starting to break open. I was in and out ...
- By SueCorvette: Sleepwalking while on lyrica
I have never had issues with sleepwalking until taking Lyrica. I have had some terrifying experiences like walking up in a hotel lobby in my short nightie. After several episodes, I stopped taking lyrica and stopped sleepwalking. Recently my doctor put me back on this drug and the first night I took ...
- By Icantremember: Off label use of drugs for peripheral neuropathy causing memory loss
I have peripheral neuropathy with standard symptoms of burning, tingling, stabbing pain on the tops of my feet. I have had this condition for over 15 years getting worse over time. The last 5 years I have seen a couple of doctors and through trial and error we settled on a combination of Savella and ...
Recent related drug studies:
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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
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