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Home > Flexeril > Lyrica > Flexeril and Lyrica

Review: Flexeril and Lyrica

Summary: drug interactions are reported among people who take Flexeril and Lyrica together.

This review analyzes the effectiveness and drug interactions between Flexeril and Lyrica. It is created by eHealthMe based on reports of 1,714 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Flexeril and Lyrica >>>

What are the drugs

Flexeril (latest outcomes from 16,437 users) has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms.

Trend of flexeril reports

Lyrica (latest outcomes from 66,552 users) has active ingredients of pregabalin. It is often used in fibromyalgia.

Trend of lyrica reports

On Nov, 25, 2014: 1,714 people who take Flexeril, Lyrica are studied

Flexeril, Lyrica outcomes

Drug combinations in study:
- Flexeril (cyclobenzaprine hydrochloride)
- Lyrica (pregabalin)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Flexeril is effective0.00%
(0 of 9 people)
9.09%
(1 of 11 people)
10.00%
(1 of 10 people)
27.27%
(3 of 11 people)
37.50%
(12 of 32 people)
21.43%
(3 of 14 people)
50.00%
(3 of 6 people)
50.00%
(1 of 2 people)
Lyrica is effective16.67%
(2 of 12 people)
21.74%
(5 of 23 people)
14.29%
(1 of 7 people)
33.33%
(6 of 18 people)
30.77%
(8 of 26 people)
44.44%
(4 of 9 people)
n/a0.00%
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
DizzinessAnxietyMulti-organ FailurePainDepressionIrritabilityMuscle Contractions InvoluntaryPain
Vision BlurredDepressionHyperhidrosisAnxietyPainDepressionDry MouthAnxiety
Drug IneffectiveDizzinessNeutropeniaDepressionAnxietyBlood Cholesterol IncreasedAnxiety AggravatedOedema Peripheral
SomnolencePainSeptic ShockDizzinessWeight DecreasedDaydreamingIrritable Bowel SyndromeNausea
NauseaDrug IneffectiveAnxietyInsomniaParanoiaErythemaPanic Disorder With AgoraphobiaFatigue
Dry MouthWeight IncreasedWeight DecreasedConstipationDiabetes MellitusBlood Thyroid Stimulating Hormone IncreasedStiffness In A JointBack Pain
Oedema PeripheralNervousnessAmnesiaNauseaWeight IncreasedHypertensionFrequent HeadachesDrug Ineffective
PainConfusional StateDyspepsiaCardiac DisorderHypoaesthesiaWeight IncreasedBody OverheatingWeight Increased
Weight DecreasedNauseaWithdrawal SyndromeTremorMulti-organ FailureOedema PeripheralMeniere's DiseaseHypoaesthesia
Memory ImpairmentHypersensitivityNauseaHeadacheNeutropeniaSleep DisorderDry Eyes AggravatedArthralgia

Drug effectiveness by gender :

FemaleMale
Flexeril is effective25.93%
(21 of 81 people)
21.43%
(3 of 14 people)
Lyrica is effective28.05%
(23 of 82 people)
21.43%
(3 of 14 people)

Most common drug interactions by gender * :

FemaleMale
PainPain
Oedema PeripheralAnxiety
AnxietyNeuropathy Peripheral
NauseaDrug Ineffective
FatigueDizziness
Weight IncreasedFatigue
Drug IneffectiveBack Pain
Back PainDyspnoea
OsteoarthritisConstipation
DyspnoeaHypoaesthesia

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Flexeril is effectiven/an/a100.00%
(1 of 1 people)
0.00%
(0 of 18 people)
16.67%
(9 of 54 people)
19.51%
(8 of 41 people)
5.97%
(4 of 67 people)
12.50%
(2 of 16 people)
Lyrica is effectiven/an/a0.00%
(0 of 1 people)
5.26%
(1 of 19 people)
18.18%
(10 of 55 people)
25.00%
(9 of 36 people)
5.88%
(4 of 68 people)
12.50%
(2 of 16 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Foetal Exposure During Pregnancyn/aConvulsionPain In ExtremityPainPainPainPain
DeathConversion DisorderPulmonary EmbolismWeight IncreasedDrug IneffectiveOedema PeripheralAnxiety
DisorientationChest PainDepressionMuscle SpasmsFatigueAnaemia
Hallucination, AuditoryHypoaesthesiaDyspnoeaArthralgiaAnxietyHypertension
PyrexiaInsomniaDizzinessSomnolenceOsteoarthritisOedema Peripheral
AstheniaPulmonary EmbolismAnxietyNauseaOsteoarthritis
BronchitisNauseaDepressionHypoaesthesiaNausea
Influenza Like IllnessAbdominal Pain UpperVomitingWeight IncreasedArthralgia
CholecystitisAnxietyDyspnoeaOsteoporosisBack Pain
Cardiac Failure CongestiveFeeling AbnormalMemory ImpairmentBone PainDizziness

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Flexeril and Lyrica?

You are not alone! Join a related mobile support group:
- support group for people who take Flexeril and Lyrica
- support group for people who take Flexeril
- support group for people who take Lyrica

Recent conversations of related support groups:

  • Support group for people who take Lyrica
    Hey Everyone! Joanne_Lilo, I'm sorry about the car accident! This is listed on Lyrica's drug information: "Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself." Have you told your doctor?

Latest outcomes in real world:

Can you answer these questions (Ask a question):

  • Why would i get copd since i never smoked?
    (Asked by a 62 year old woman who has Rheumatoid Arthritis, PBC, AIH, Asthma, and takes Vitamin D, Calcium Carbonate, Anturol, Morphine Sulfate, Levothyroxine Sodium, Pyridium, Cyclobenzaprine Hydrochloride, Azathioprine, Proair Hfa, Advair Diskus 250/50, Combivent)
    I have several autoimmune disorders, I was shocked to get the COPD diagnosis since I have never smoked but I had second hand smoke first 23 years of my life. My doctor said my Autoimmune Hepatitis and Primary Biliary Cholingitis set me up for COPD.

  • Propranolo & pregabalin - do they produce heart troubles? my meds mix has
    (Asked by a 46 year old man who has Angina, Panic, Anxiety, and takes Zopiclone, Pregabalin, Propranolol Hydrochloride)
    Being on zopiclone 75mg (sleep med) gave me terrible poly/firbomyalgia, which I was then prescrbed pregabalin to aleviate pains and anxiety, and the propranolo to help with the same. On day one of propranolo I had a medium heart attack like event, within 24hrs had a large attack and became hospitali ...

  • I have an enlarged liver...could i use buprenorphine?
    (Asked by a 33 year old woman who has Enlarged Liver, and takes Allopurinol, Metformin, Lyrica, Morphine)
    I want to know if i can take buprenorphine with an enlarged liver

  • I cannot get a direct answer from any of my drs.,is my sciatic pain caused by my interstitail cystitus?
    (Asked by a 36 year old woman who has Prolapse Heart Valve/murmor, Sciatica, Interstitail Cystitus,, and takes Hydroxyzine, Amitriptyline Hydrochloride, Cyclobenzaprine Hydrochloride, Estradiol )
    I have had interstitail cystitus for almost four years now.I have been on every kind of drug,other than pain pills.I will not take them,I don't believe in them they only mask the problem and cause addiction.of course,just my belief.I have had d.s.m.o. repetitively for first year and a half twice a w ...

  • Can droopy eyelid be caused by a bump and/or pregabalin?
    (Asked by a 43 year old woman who has Droopy Eyelid, and takes Pregabalin)
    Had a bad bump on my forehead a couple of weeks ago and my whole face went black. Mostly better now but Im let with a badly drooping eyelid (right) which the doctors tell me will go away. No sign of that at the moment but Ive read that pregabalin (which I take in small doses, can cause this. It ...

More questions for: Flexeril, Lyrica

You may be interested at these reviews (Write a review):

  • 3 strong drugs together against neuropathic pain
    (Posted by a 49 year old man who has Ehlers-danlos Syndrome, Joint Hypermobility, Neuropathic Pain, and takes Pregabalin, Clonazepam, Methadone Hydrochloride)
    Neuropathic pain debuted when I was 24, now I'm 50. Received diagnosed with Ehler-Danlos syndrome (EDS), joint hypermobility type, when I was 35 years old. So it can take some time to get a diagnose. And as EDS-patient I do not belong to any clinic. Orthopedics says that EDS is not orthopedic, rheum ...

  • Nexium improves my constipation
    (Posted by a 53 year old woman who has Constipation, GERD, and takes Lyrica, Methadone Hydrochloride, Lipitor)
    Started taking Nexium 1 week ago and I noticed improvement with my chronic constipation.

  • Nightmare on lyrica st.
    (Posted by a 55 year old man who has R.S.D Type 3 Right Lower Leg & Foot, Bulging Disc L 5, and takes Lyrica)
    r.knee revision 3rd.and last time due from Mersa infection and blood clot left me 1 1/2 shorter on r. Leg. Lost a lot of nerves in foot lower r. Leg.bulging disc was from falling from knee revision and for 9 months had no knee and on crutches.had lots of falls and blew out lower back. Put me on lyri ...

  • Lyrica varied widely
    (Posted by a 69 year old woman who has Peripheral Neuropathy, Chronic Pain, Bright-red Rash, Swelling Of Ankles, Weight Gain, and takes Lyrica)
    I was prescribed Lyrica for treatment of chronic pain. It was ineffective, but it knocked out the symptoms of interstitial. However, it also caused rapid weight gain (I went from 110 to 130 lbs. in just a few weeks) and my ankles started to swell. The pain doctor advised me to discontinue the dru ...

  • Lyrica photosensitivity
    (Posted by a 58 year old woman who has Depression - Major, Fibromyalgia, and takes Xanax, Lyrica)
    Spent several hours outside in partly sunny conditions on Sat. Swelling started a little on Sun. But by Monday my face was ver swollen and red with small bumps most noticeable across the cheeks, nose and area of the forehead where bangs did not cover. I have only been using for (6) months. Un ...

More reviews for: Flexeril, Lyrica

Complete drug side effects:

On eHealthMe, Flexeril (cyclobenzaprine hydrochloride) is often used to treat muscle spasms. Lyrica (pregabalin) is often used to treat fibromyalgia. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug studies (Check your drugs):

More related studies for: Flexeril, Lyrica

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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