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Review: Flexeril and Lyrica

This review analyzes the effectiveness and drug interactions between Flexeril and Lyrica. It is created by eHealthMe based on reports of 1,713 people who take the same drugs from FDA and social media, and is updated regularly.

Get connected: join a mobile support group for people who take Flexeril and Lyrica >>>

What are the drugs

Flexeril (latest outcomes from 16,427 users) has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms.

Lyrica (latest outcomes from 66,503 users) has active ingredients of pregabalin. It is often used in fibromyalgia.

On Sep, 14, 2014: 1,713 people who take Flexeril, Lyrica are studied

Flexeril, Lyrica outcomes

Drug combinations in study:
- Flexeril (cyclobenzaprine hydrochloride)
- Lyrica (pregabalin)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Flexeril is effective0.00%
(0 of 9 people)
9.09%
(1 of 11 people)
10.00%
(1 of 10 people)
27.27%
(3 of 11 people)
35.48%
(11 of 31 people)
21.43%
(3 of 14 people)
50.00%
(3 of 6 people)
50.00%
(1 of 2 people)
Lyrica is effective16.67%
(2 of 12 people)
21.74%
(5 of 23 people)
14.29%
(1 of 7 people)
33.33%
(6 of 18 people)
32.00%
(8 of 25 people)
44.44%
(4 of 9 people)
n/a0.00%
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
DizzinessAnxietyMulti-organ FailurePainDepressionIrritabilityMuscle Contractions InvoluntaryPain
Vision BlurredDepressionHyperhidrosisAnxietyPainDepressionDry MouthAnxiety
Drug IneffectiveDizzinessNeutropeniaDepressionAnxietyBlood Cholesterol IncreasedAnxiety AggravatedOedema Peripheral
SomnolencePainSeptic ShockDizzinessWeight DecreasedDaydreamingIrritable Bowel SyndromeNausea
NauseaDrug IneffectiveAnxietyInsomniaParanoiaErythemaPanic Disorder With AgoraphobiaFatigue
Dry MouthWeight IncreasedWeight DecreasedConstipationDiabetes MellitusBlood Thyroid Stimulating Hormone IncreasedStiffness In A JointBack Pain
Oedema PeripheralNervousnessAmnesiaNauseaWeight IncreasedHypertensionFrequent HeadachesDrug Ineffective
PainConfusional StateDyspepsiaCardiac DisorderHypoaesthesiaWeight IncreasedBody OverheatingWeight Increased
Weight DecreasedNauseaWithdrawal SyndromeTremorMulti-organ FailureOedema PeripheralMeniere's DiseaseHypoaesthesia
Memory ImpairmentHypersensitivityNauseaHeadacheNeutropeniaSleep DisorderDry Eyes AggravatedArthralgia

Drug effectiveness by gender :

FemaleMale
Flexeril is effective25.00%
(20 of 80 people)
21.43%
(3 of 14 people)
Lyrica is effective28.40%
(23 of 81 people)
21.43%
(3 of 14 people)

Most common drug interactions by gender * :

FemaleMale
PainPain
Oedema PeripheralAnxiety
AnxietyNeuropathy Peripheral
NauseaDrug Ineffective
Weight IncreasedDizziness
FatigueFatigue
Drug IneffectiveBack Pain
Back PainDyspnoea
OsteoarthritisConstipation
DyspnoeaHypoaesthesia

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Flexeril is effectiven/an/a100.00%
(1 of 1 people)
0.00%
(0 of 18 people)
15.09%
(8 of 53 people)
19.51%
(8 of 41 people)
5.97%
(4 of 67 people)
12.50%
(2 of 16 people)
Lyrica is effectiven/an/a0.00%
(0 of 1 people)
5.26%
(1 of 19 people)
18.52%
(10 of 54 people)
25.00%
(9 of 36 people)
5.88%
(4 of 68 people)
12.50%
(2 of 16 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Foetal Exposure During Pregnancyn/aConvulsionPain In ExtremityPainPainPainPain
DeathConversion DisorderPulmonary EmbolismWeight IncreasedDrug IneffectiveOedema PeripheralAnxiety
DisorientationChest PainDepressionMuscle SpasmsFatigueAnaemia
Hallucination, AuditoryHypoaesthesiaDyspnoeaArthralgiaAnxietyHypertension
PyrexiaInsomniaDizzinessSomnolenceOsteoarthritisOedema Peripheral
AstheniaPulmonary EmbolismAnxietyNauseaOsteoarthritis
BronchitisNauseaDepressionHypoaesthesiaNausea
Influenza Like IllnessAbdominal Pain UpperVomitingWeight IncreasedArthralgia
CholecystitisFeeling AbnormalDyspnoeaOsteoporosisBack Pain
Cardiac Failure CongestiveAnxietyMemory ImpairmentBone PainDizziness

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Flexeril and Lyrica?

Get connected! Join a mobile support group:
- group for people who take Flexeril and Lyrica
- group for people who take Flexeril
- group for people who take Lyrica

Comments from related studies:

  • From this study (4 months ago):

  • nerve twitching in hands and sometimes face. Muscle spasms from head to toe. Severe Migraines

    Reply

  • From this study (5 months ago):

  • Went off ambien cold turkey and started on clonidine, went to arthritis Dr and said fibromyalgia and she put me on lyrics 50 Mg 3 times a day but pain is worse. I have to take 10/325 percoset that only helps a little.

    Reply

  • From this study (8 months ago):

  • I am suffering from severe mood swings and nervousness. Sometimes I am so mad I want to rip something apart, most of the time my poor husband catches the brunt of it. My headaches are coming back, but I really want to get rid of the crazy mood swings before I hurt myself or someone else when i lose my temper maybe in a car driving, I will fly into a rage over little things...Please help me with this.
    What do I need to get OFF of OR ON...
    Thank you, Carolyn

    Reply

Post a new comment    OR    Read more comments

Can you answer these questions (what is this?):

More questions for: Flexeril, Lyrica

You may be interested at these reviews (what is this?):

  • Lyrica varied widely
    I was prescribed Lyrica for treatment of chronic pain. It was ineffective, but it knocked out the symptoms of interstitial. However, it also caused rapid weight gain (I went from 110 to 130 lbs. in just a few weeks) and my ankles started to swell. The pain doctor advised me to discontinue the dru ...

  • Lyrica photosensitivity
    Spent several hours outside in partly sunny conditions on Sat. Swelling started a little on Sun. But by Monday my face was ver swollen and red with small bumps most noticeable across the cheeks, nose and area of the forehead where bangs did not cover. I have only been using for (6) months. Un ...

  • I wish i had never taken ambien
    Ambien was prescribed after my sleep study showed severe sleep latency and awakening. In the five hours I slept I woke 85 times and had only 5 minutes of deep sleep. However, the doctors couldn't make a recommendation because they could detect no cause for the poor sleep pattern. My doctor offered A ...

More reviews for: Flexeril, Lyrica

Complete drug side effects:

On eHealthMe, Flexeril (cyclobenzaprine hydrochloride) is often used to treat muscle spasms. Lyrica (pregabalin) is often used to treat fibromyalgia. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

 

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