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Review: Flexeril and Lyrica

This review analyzes the effectiveness and drug interactions between Flexeril and Lyrica. It is created by eHealthMe based on reports of 1,713 people who take the same drugs from FDA and social media, and is updated regularly.

Get connected: join a mobile support group for people who take Flexeril and Lyrica >>>

What are the drugs

Flexeril (latest outcomes from 16,436 users) has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms.

Lyrica (latest outcomes from 66,519 users) has active ingredients of pregabalin. It is often used in fibromyalgia.

On Oct, 26, 2014: 1,713 people who take Flexeril, Lyrica are studied

Flexeril, Lyrica outcomes

Drug combinations in study:
- Flexeril (cyclobenzaprine hydrochloride)
- Lyrica (pregabalin)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Flexeril is effective0.00%
(0 of 9 people)
9.09%
(1 of 11 people)
10.00%
(1 of 10 people)
27.27%
(3 of 11 people)
35.48%
(11 of 31 people)
21.43%
(3 of 14 people)
50.00%
(3 of 6 people)
50.00%
(1 of 2 people)
Lyrica is effective16.67%
(2 of 12 people)
21.74%
(5 of 23 people)
14.29%
(1 of 7 people)
33.33%
(6 of 18 people)
32.00%
(8 of 25 people)
44.44%
(4 of 9 people)
n/a0.00%
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
DizzinessAnxietyMulti-organ FailurePainDepressionIrritabilityMuscle Contractions InvoluntaryPain
Vision BlurredDepressionHyperhidrosisAnxietyPainDepressionDry MouthAnxiety
Drug IneffectiveDizzinessNeutropeniaDepressionAnxietyBlood Cholesterol IncreasedAnxiety AggravatedOedema Peripheral
SomnolencePainSeptic ShockDizzinessWeight DecreasedDaydreamingIrritable Bowel SyndromeNausea
NauseaDrug IneffectiveAnxietyInsomniaParanoiaErythemaPanic Disorder With AgoraphobiaFatigue
Dry MouthWeight IncreasedWeight DecreasedConstipationDiabetes MellitusBlood Thyroid Stimulating Hormone IncreasedStiffness In A JointBack Pain
Oedema PeripheralNervousnessAmnesiaNauseaWeight IncreasedHypertensionFrequent HeadachesDrug Ineffective
PainConfusional StateDyspepsiaCardiac DisorderHypoaesthesiaWeight IncreasedBody OverheatingWeight Increased
Weight DecreasedNauseaWithdrawal SyndromeTremorMulti-organ FailureOedema PeripheralMeniere's DiseaseHypoaesthesia
Memory ImpairmentHypersensitivityNauseaHeadacheNeutropeniaSleep DisorderDry Eyes AggravatedArthralgia

Drug effectiveness by gender :

FemaleMale
Flexeril is effective25.00%
(20 of 80 people)
21.43%
(3 of 14 people)
Lyrica is effective28.40%
(23 of 81 people)
21.43%
(3 of 14 people)

Most common drug interactions by gender * :

FemaleMale
PainPain
Oedema PeripheralAnxiety
AnxietyNeuropathy Peripheral
NauseaDrug Ineffective
Weight IncreasedDizziness
FatigueFatigue
Drug IneffectiveBack Pain
Back PainDyspnoea
OsteoarthritisConstipation
DyspnoeaHypoaesthesia

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Flexeril is effectiven/an/a100.00%
(1 of 1 people)
0.00%
(0 of 18 people)
15.09%
(8 of 53 people)
19.51%
(8 of 41 people)
5.97%
(4 of 67 people)
12.50%
(2 of 16 people)
Lyrica is effectiven/an/a0.00%
(0 of 1 people)
5.26%
(1 of 19 people)
18.52%
(10 of 54 people)
25.00%
(9 of 36 people)
5.88%
(4 of 68 people)
12.50%
(2 of 16 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Foetal Exposure During Pregnancyn/aConvulsionPain In ExtremityPainPainPainPain
DeathConversion DisorderPulmonary EmbolismWeight IncreasedDrug IneffectiveOedema PeripheralAnxiety
DisorientationChest PainDepressionMuscle SpasmsFatigueAnaemia
Hallucination, AuditoryHypoaesthesiaDyspnoeaArthralgiaAnxietyHypertension
PyrexiaInsomniaDizzinessSomnolenceOsteoarthritisOedema Peripheral
AstheniaPulmonary EmbolismAnxietyNauseaOsteoarthritis
BronchitisNauseaDepressionHypoaesthesiaNausea
Influenza Like IllnessAbdominal Pain UpperVomitingWeight IncreasedArthralgia
CholecystitisFeeling AbnormalDyspnoeaOsteoporosisBack Pain
Cardiac Failure CongestiveAnxietyMemory ImpairmentBone PainDizziness

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Flexeril and Lyrica?

Get connected! Join a related mobile support group:
- support group for people who take Flexeril and Lyrica
- support group for people who take Flexeril
- support group for people who take Lyrica

Comments from related studies:

  • From this study (6 months ago):

  • nerve twitching in hands and sometimes face. Muscle spasms from head to toe. Severe Migraines

    Reply

  • From this study (7 months ago):

  • Went off ambien cold turkey and started on clonidine, went to arthritis Dr and said fibromyalgia and she put me on lyrics 50 Mg 3 times a day but pain is worse. I have to take 10/325 percoset that only helps a little.

    Reply

  • From this study (9 months ago):

  • I am suffering from severe mood swings and nervousness. Sometimes I am so mad I want to rip something apart, most of the time my poor husband catches the brunt of it. My headaches are coming back, but I really want to get rid of the crazy mood swings before I hurt myself or someone else when i lose my temper maybe in a car driving, I will fly into a rage over little things...Please help me with this.
    What do I need to get OFF of OR ON...
    Thank you, Carolyn

    Reply

Post a new comment    OR    Read more comments

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More reviews for: Flexeril, Lyrica

Complete drug side effects:

On eHealthMe, Flexeril (cyclobenzaprine hydrochloride) is often used to treat muscle spasms. Lyrica (pregabalin) is often used to treat fibromyalgia. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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