Review: Flexeril and Melatonin drug interactions
This review analyzes the interactions between Flexeril and Melatonin. It is created by eHealthMe based on 84 people who have drug interactions while taking the drugs. The review uses reports from FDA and social media, and is updated regularly.
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What are the drugs
Flexeril (latest outcomes from 16,348 users) has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms.
Melatonin (latest outcomes from 2,545 users) has active ingredients of melatonin. It is often used in insomnia.
On Feb, 27, 2014: 84 people who reported to have interactions when taking Flexeril, Melatonin are studied
Drug combinations in study:
- Flexeril (cyclobenzaprine hydrochloride)
- Melatonin (melatonin)
Most common interactions experienced by people in the use of Flexeril, Melatonin:(click on each outcome to view in-depth analysis, incl. how people recovered)
|Interaction||Number of reports|
|Fatigue (feeling of tiredness)||24|
|Pain In Extremity||14|
Most common interactions experienced by people in long term use of Flexeril, Melatonin:(click on each outcome to view in-depth analysis, incl. how people recovered)
|Interaction||Number of reports|
|Muscle Fatigue (a condition in which muscles cannot exert their normal force)||2|
|Headaches (pain in head)||2|
|Exhaustion, Fatigue, Lethargy, Tiredness, Weariness (feeling of tiredness)||2|
|Loss Of Sensation, Numbness And Tingling, Paresthesias, Sensory Loss, Tingling And Numbness (unusual prickling sensations)||2|
|Sweating - Excessive (abnormally increased sweating)||2|
|High Blood Pressure||1|
|Foetal Heart Rate||1|
How effective are the drugs:
|not at all||somewhat||moderate||high||very high|
Top conditions involved for these people * :
- Sleep disorder
Top co-used drugs for these people * :
* Approximation only. Some reports may have incomplete information.
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Complete drug side effects:
On eHealthMe, Flexeril (cyclobenzaprine hydrochloride) is often used to treat muscle spasms. Melatonin (melatonin) is often used to treat insomnia. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.
What is the drug used for and how effective is it:
- Flexeril is used in:
- Melatonin is used in:
Other drugs that are used to treat the same conditions:
- Flexeril alternatives:
- Melatonin alternatives:
Comments from related studies:
From this study (1 year ago):
From this study (1 year ago):
From this study (2 years ago):
I have had issues with high blood pressure for years & lost 60 pounds & still have to take 3 different medications for it. I have Candida severely & need to get rid of it & am wondering if any or all of these medications I am taking is cuasing any of these issues. I also have gluten issues, wheat issues, starch issues, peanut butter, chocolate, peanuts, nuts, white rice, potato issues, I can't eat a lot of foods & am struggling with my health. Please help!
Can any one of these medications, or any combination of them, cause ataxia?
Actonel: After approx 2 years of usage developed spontaneous left hip stress fracture and subsequent complete fracture of the hip. After workup by endocrinologist Actonel was stopped due to suspicion of this being contributing to cause of fracture.
Can you answer these questions (what is this?):
- By InsomniaRampant: Can a person use trazodone and dexamethasone?
I have only been on this for one day started like a moron at 8pm and ive been on it once before on a high dose but this is like 1mg bid for 7 days and i had a recent discovery im allergic to oxycontin as i would randomly pass out or be awake for days tripping, havent ever been on it before. Only rea ...
- By meisels: Can melatonin cause precocious puberty
can the use of Melatonin to help kids (girls) fall asleep cause Precocious puberty?
- By Bob: Are there any reports of extreme dry mouth?
Since having an aortic valve replacement via TAVR (newer technique)I have had various medications added to my schedule. For the last several months I seem to have a very dry mouth problem. I have given you a few that I am taking at the present time that I thought might have some effect on my dryne ...
You may be interested at these reviews (what is this?):
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I have taken melatonin for insomnia I've been experiencing recently (not a chronic condition). I haven't had any problems or interactions with my other regular medications while using the melatonin, other than drowsiness in the morning. Last night I had a migraine at bedtime, so took 50 mg. of imi ...
- By Nikkiney.79: Living with chronic pain while battling with psychological disorders.
I have had back problems since 2004. I have been on pain management since 2007. A year ago I was diagnosed with Fibromyalgia. Not only does fibromyalgia cause deep wide spread pain, it also makes me feel lethargic, fluish, and greatly effects my daily life. I also have some psychological conditions ...
- By Ichikirei: Savella & synthroid hell!
Within 15 minutes of taking Savella, the heat starts in my face and the sweating begins unrelentlessly. And the palpitations begin right away and later will be strong enough to wake me from sleep. Its horrible! I cant go anywhere! I cant tolerate any additional heat anywhere! And if I go out, I m ...
Recent related drug studies:
- A study of drug interactions between Clonidine Hydrochloride, Cyclobenzaprine Hydrochloride, Atenolol, Lisinopril, Acyclovir, L-Lysine Hydrochloride, B Complex Vitamin, Melatonin, CoQ10, Excedrin, Excedrin, Fish Oil Fatty Acid, Magnesium, Multivitamin, Probiotic, Sumatriptan Succinate, Lactobacillus Acidophilus, Nystatin, Golytely for a patient with High Blood Pressure, Muscle Relaxant Therapy, Cold Sore, Cramps - Muscle, Sleeping Difficulty, Migraine, Pain - Back, Arterial Repair, Vitamin E, Bacteriuria, Oral Thrush, Constipation. The patient has Candida Test Positive, Candida Nos, Candidal Infection Nos, Candidiasis, Food Intolerance, Food Allergy
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- A study of drug interactions between Neurontin, Norco, Zantac 150, Metformin Hydrochloride, Toprol-xl, Flexeril, Aspirin, Relafen, Ambien, Amitriptyline Hydrochloride, Estrace, Tamsulosin Hydrochloride, Bactrim, Calcium Carbonate, Famotidine And Magnesium Hydroxide, Multivitamin, Melatonin, Colace for a patient with Trigeminal Neuralgia, Pain Management, Antacid Therapy, Hypoglycemia, Paroxysmal Arrhythmia, Muscle Spasms, Anticoagulant Therapy, Antiinflammatory Therapy, Sleep Disorder Due To A General Medical Condition, Pain Prophylaxis, Hormone Therapy, Urinary Retention, Urinary Tract Infection - Chronic Or Recurrent, Osteopenia, Vitamin C, Stool Softener. The patient has Acetone, Fracture (Broken bone)
NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
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