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Review: Flexeril and Melatonin

This review analyzes the effectiveness and drug interactions between Flexeril and Melatonin. It is created by eHealthMe based on 87 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

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On Mar, 29, 2014: 87 people who reported to have interactions when taking Flexeril, Melatonin are studied

Trend of Flexeril, Melatonin's drug interactions, side effects and effectiveness reports (4280376)

Drug combinations in study:
- Flexeril (cyclobenzaprine hydrochloride)
- Melatonin (melatonin)

eHealthMe real world results:

Most common interactions experienced by people in the use of Flexeril, Melatonin:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Diarrhoea46
Anxiety36
Pain35
Fatigue (feeling of tiredness)29
Depression27
Drug Ineffective24
Fall18
Back Pain17
Injury16
Pain In Extremity16

Most common interactions experienced by people in long term use of Flexeril, Melatonin:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Muscle Fatigue (a condition in which muscles cannot exert their normal force)2
Headaches (pain in head)2
Exhaustion, Fatigue, Lethargy, Tiredness, Weariness (feeling of tiredness)2
Urinary Frequency2
Loss Of Sensation, Numbness And Tingling, Paresthesias, Sensory Loss, Tingling And Numbness (unusual prickling sensations)2
Sweating - Excessive (abnormally increased sweating)2
Food Allergy1
High Blood Pressure1
Presyncope1
Foetal Heart Rate1

How effective are the drugs:

not at allsomewhatmoderatehighvery high
Flexeril0.00%25.00%75.00%0.00%0.00%
Melatonin0.000.000.000.000.00

Top conditions involved for these people * :

  1. Pain
  2. Sleep disorder
  3. Depression
  4. Insomnia
  5. Fibromyalgia

Top co-used drugs for these people * :

  1. Ambien
  2. Aspirin
  3. Cymbalta
  4. Multi-vitamins
  5. Vitamin d

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Flexeril, Melatonin

You can also:

Complete drug side effects:

On eHealthMe, Flexeril (cyclobenzaprine hydrochloride) is often used to treat muscle spasms. Melatonin (melatonin) is often used to treat insomnia. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Comments from related studies:

  • From this study (1 year ago):

  • I have had issues with high blood pressure for years & lost 60 pounds & still have to take 3 different medications for it. I have Candida severely & need to get rid of it & am wondering if any or all of these medications I am taking is cuasing any of these issues. I also have gluten issues, wheat issues, starch issues, peanut butter, chocolate, peanuts, nuts, white rice, potato issues, I can't eat a lot of foods & am struggling with my health. Please help!

    Reply

  • From this study (1 year ago):

  • Can any one of these medications, or any combination of them, cause ataxia?

    Reply

  • From this study (2 years ago):

  • Actonel: After approx 2 years of usage developed spontaneous left hip stress fracture and subsequent complete fracture of the hip. After workup by endocrinologist Actonel was stopped due to suspicion of this being contributing to cause of fracture.

    Reply

Can you answer these questions (what is this?):

More questions for: Flexeril, Melatonin

You may be interested at these reviews (what is this?):

  • Bad side effect of melatonin/imitrex use together
    I have taken melatonin for insomnia I've been experiencing recently (not a chronic condition). I haven't had any problems or interactions with my other regular medications while using the melatonin, other than drowsiness in the morning. Last night I had a migraine at bedtime, so took 50 mg. of imi ...

  • Living with chronic pain while battling with psychological disorders.
    I have had back problems since 2004. I have been on pain management since 2007. A year ago I was diagnosed with Fibromyalgia. Not only does fibromyalgia cause deep wide spread pain, it also makes me feel lethargic, fluish, and greatly effects my daily life. I also have some psychological conditions ...

  • Savella & synthroid hell!
    Within 15 minutes of taking Savella, the heat starts in my face and the sweating begins unrelentlessly. And the palpitations begin right away and later will be strong enough to wake me from sleep. Its horrible! I cant go anywhere! I cant tolerate any additional heat anywhere! And if I go out, I m ...

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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