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Home > Flexeril > Melatonin > Flexeril and Melatonin

Review: Flexeril and Melatonin

Summary: drug interactions are reported among people who take Flexeril and Melatonin together.

This review analyzes the effectiveness and drug interactions between Flexeril and Melatonin. It is created by eHealthMe based on reports of 105 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Flexeril and Melatonin >>>

What are the drugs

Flexeril (latest outcomes from 16,437 users) has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms.

Trend of flexeril reports

Melatonin (latest outcomes from 2,653 users) has active ingredients of melatonin. It is often used in insomnia.

Trend of melatonin reports

On Nov, 26, 2014: 105 people who take Flexeril, Melatonin are studied

Flexeril, Melatonin outcomes

Drug combinations in study:
- Flexeril (cyclobenzaprine hydrochloride)
- Melatonin (melatonin)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Flexeril is effective0.00%
(0 of 1 people)
50.00%
(2 of 4 people)
n/a50.00%
(2 of 4 people)
75.00%
(3 of 4 people)
0.00%
(0 of 2 people)
0.00%
(0 of 1 people)
n/a
Melatonin is effectiven/a16.67%
(1 of 6 people)
66.67%
(2 of 3 people)
25.00%
(1 of 4 people)
0.00%
(0 of 2 people)
n/an/an/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Exhaustion, Fatigue, Lethargy, Tiredness, WearinessNauseaNauseaRestless Legs SyndromeCandidiasisFood IntoleranceVaginal SloughingPain
DystoniaDiarrheaDiarrheaMuscle FatigueFood IntoleranceFood AllergyDepression
Language Disorder - ExpressiveExhaustion, Fatigue, Lethargy, Tiredness, WearinessPain In JawPresyncopeFood AllergyCandidiasisFatigue
CataplexyVertigoPain - BackDiarrheaCandidal Infection NosCandidal Infection NosDiarrhoea
Spasm Of The EsophagusOrthostatic HypotensionInsomniaNauseaFractureAnxiety
SpasticityPain - JointsKnee PainHigh Blood PressureDrug Ineffective
Neuropathy - PeripheralMusculoskeletal PainSweating - ExcessiveBack Pain
Restless Legs SyndromeMusculoskeletal StiffnessUrinary FrequencyInsomnia
Numbness And TinglingNumbness And TinglingHeadachesInjury
Musculoskeletal StiffnessParkinsonismLoss Of Sensation, Numbness And Tingling, Paresthesias, Sensory Loss, Tingling And NumbnessPain In Extremity

Drug effectiveness by gender :

FemaleMale
Flexeril is effective45.45%
(5 of 11 people)
40.00%
(2 of 5 people)
Melatonin is effective33.33%
(4 of 12 people)
0.00%
(0 of 3 people)

Most common drug interactions by gender * :

FemaleMale
Drug IneffectiveDiarrhoea
PainPain
InsomniaPain In Extremity
DepressionBone Pain
FatigueBack Pain
NauseaCellulitis
Abdominal PainBone Lesion
Heart Rate IncreasedBone Disorder
ParaesthesiaOsteonecrosis Of Jaw
DyspnoeaCystitis

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Flexeril is effectiven/an/an/a16.67%
(1 of 6 people)
4.76%
(1 of 21 people)
15.00%
(3 of 20 people)
100.00%
(2 of 2 people)
0.00%
(0 of 3 people)
Melatonin is effectiven/an/an/a0.00%
(0 of 10 people)
5.00%
(1 of 20 people)
5.00%
(1 of 20 people)
100.00%
(1 of 1 people)
33.33%
(1 of 3 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/an/aPulmonary EmbolismNauseaPainFatigueDrug IneffectiveDiarrhoea
Deep Vein ThrombosisPain In JawArthralgiaPainDyspnoeaDepression
DiarrheaDepressionAnxietyRespiratory FailureFall
Pulmonary EmbolismInsomniaDepressionMental Status ChangesHyperhidrosis
Deep Vein ThrombosisFeeling AbnormalBack PainSeptic ShockMyocardial Infarction
Pain - BackBlood Creatinine IncreasedDiarrhoeaRenal Failure AcuteMuscle Spasms
Knee PainAngerPain In ExtremityIschaemic HepatitisWeight Decreased
InsomniaCervicobrachial SyndromeCellulitisAcute Coronary SyndromeMuscle Strain
Skin UlcerBone LesionAbdominal PainDrug Ineffective
DyspepsiaBone DisorderPanic AttackInjury

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Flexeril and Melatonin?

You are not alone! Join a related mobile support group:
- support group for people who take Flexeril and Melatonin
- support group for people who take Flexeril
- support group for people who take Melatonin

Can you answer these questions (Ask a question):

  • Why would i get copd since i never smoked?
    (Asked by a 62 year old woman who has Rheumatoid Arthritis, PBC, AIH, Asthma, and takes Vitamin D, Calcium Carbonate, Anturol, Morphine Sulfate, Levothyroxine Sodium, Pyridium, Cyclobenzaprine Hydrochloride, Azathioprine, Proair Hfa, Advair Diskus 250/50, Combivent)
    I have several autoimmune disorders, I was shocked to get the COPD diagnosis since I have never smoked but I had second hand smoke first 23 years of my life. My doctor said my Autoimmune Hepatitis and Primary Biliary Cholingitis set me up for COPD.

  • I cannot get a direct answer from any of my drs.,is my sciatic pain caused by my interstitail cystitus?
    (Asked by a 36 year old woman who has Prolapse Heart Valve/murmor, Sciatica, Interstitail Cystitus,, and takes Hydroxyzine, Amitriptyline Hydrochloride, Cyclobenzaprine Hydrochloride, Estradiol )
    I have had interstitail cystitus for almost four years now.I have been on every kind of drug,other than pain pills.I will not take them,I don't believe in them they only mask the problem and cause addiction.of course,just my belief.I have had d.s.m.o. repetitively for first year and a half twice a w ...

  • Can raynauds syndrome cause moderate neuraopathy?
    (Asked by a 44 year old woman who has Cervical Fusion, Moderate Neuropathy, Raynauds Syndrome, and takes Flexeril)
    I have been diagnosed with moderate neuropathy. After multiple blood tests and diabetes testing, the doctor concluded that the cause of the neuropathy is unknown, possible genetic. In talking with my family, I cannot identify anyone who has/had this diagnosis. I am receiving no treatment at this tim ...

  • Can rituxan cause bipolar disorder?
    (Asked by a 64 year old woman who has Rheumatoid Arthritis, Bipolar Disorder, and takes Depakote, Cyclobenzaprine Hydrochloride, Hydromorphone Hydrochloride, Abilify)
    recently started rituxan. Now have bipolar disorder. Could there be any connection?

  • Can flexiral withdraw cause angina? also notice when it's time for a bowel movement
    (Asked by a 59 year old woman who has Chest And Left Arm Neck And Jaw Pain, and takes Flexeril, Lisinopril)
    I've had a resent (2 weeks ago) stress and nucular scan with no sign of heart attack. Also I get this feeling occasionally before a bowel movement

More questions for: Flexeril, Melatonin

You may be interested at these reviews (Write a review):

  • I need advise, badly ckd!!
    (Posted by a 49 year old woman who has Constipation, Peripheral Neuropathy, Orthostatic Hypotension, Chronic Kidney Disease, and takes Milk Thistle, Zolpidem, Melatonin, Xanax, Adderall 30, Zorvolex)
    The orthostatic BP started in mid April, I was only dizzy upon wakening then it would subside. I have never been a big breakfast eater so I started doing that. We were in Disney later in April and I was extremely fatigued, to the point of not wanting to walk, Disney would be the first time I passe ...

  • Melatonin reduces essential tremor of the hand
    (Posted by a 64 year old woman who has Essential Tremor, and takes Fish Oil, Vitamin D, Atenolol, Melatonin)
    After taking Melatonin 1mg as a sleep aid for several nights, I noticed that my essential tremor of the hand was showing improvement. Within a week the tremor was almost unnoticeable, and I could print and write neatly, even when slightly stressed at work. I haven't seen this response reported any ...

  • I wish i had never taken ambien
    (Posted by a 43 year old woman who has Fibromyalgia, and takes Savella, Lyrica, Synthroid, Effexor, Tramadol, Duragesic-50, Flexeril, Ambien)
    Ambien was prescribed after my sleep study showed severe sleep latency and awakening. In the five hours I slept I woke 85 times and had only 5 minutes of deep sleep. However, the doctors couldn't make a recommendation because they could detect no cause for the poor sleep pattern. My doctor offered A ...

  • Melatonin and diarrhea
    (Posted by a 73 year old man who has Sleep Disorder, and takes Melatonin)
    I have had difficulty sleeping most of my life. Difficulty going to sleep and waking up multiple times during the night were a usual pattern for me. Testing for sleep apnea did not show a positive result. A friend said to try Melatonin that for him it worked fine. I tried it and the diarrhea st ...

  • Melatonin and skin dryness
    (Posted by a 27 year old man who has Dry Skin And Cold Weather Itch, and takes Melatonin)
    I've been having hard time to sleep, so I started taking Melatonin. It is OTC sleep aid with melatonin and herbal treatment (lemon balm and camomile). about three days after started taking the drug, my back of hands started showing red rashes, then neck and around lips. a week after taking medica ...

More reviews for: Flexeril, Melatonin

Complete drug side effects:

On eHealthMe, Flexeril (cyclobenzaprine hydrochloride) is often used to treat muscle spasms. Melatonin (melatonin) is often used to treat insomnia. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug studies (Check your drugs):

More related studies for: Flexeril, Melatonin

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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