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Review: Flexeril and Methotrexate

This review analyzes the effectiveness and drug interactions between Flexeril and Methotrexate. It is created by eHealthMe based on reports of 1,205 people who take the same drugs from FDA and social media, and is updated regularly.

Get connected: join a mobile support group for people who take Flexeril and Methotrexate >>>

What are the drugs

Flexeril (latest outcomes from 16,436 users) has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms.

Methotrexate (latest outcomes from 131,165 users) has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis.

On Oct, 28, 2014: 1,205 people who take Flexeril, Methotrexate are studied

Flexeril, Methotrexate outcomes

Drug combinations in study:
- Flexeril (cyclobenzaprine hydrochloride)
- Methotrexate (methotrexate sodium)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Flexeril is effective25.00%
(1 of 4 people)
0.00%
(0 of 3 people)
0.00%
(0 of 3 people)
66.67%
(2 of 3 people)
25.00%
(1 of 4 people)
75.00%
(3 of 4 people)
80.00%
(4 of 5 people)
n/a
Methotrexate is effectiven/a0.00%
(0 of 3 people)
0.00%
(0 of 2 people)
100.00%
(1 of 1 people)
30.00%
(3 of 10 people)
0.00%
(0 of 2 people)
42.86%
(3 of 7 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Muscle SpasmsPneumoniaCellulitisOsteonecrosisDiarrhoeaHypoglycaemiaNauseaPain
RetchingCellulitisHyperkeratosisGraft DysfunctionDehydrationLiver Function Test AbnormalSepsisFatigue
VomitingNauseaHypersensitivityHaematomaColitis CollagenousInterstitial Lung DiseaseRheumatoid ArthritisArthralgia
StomatitisDecreased AppetiteInflammatory Bowel DiseaseHot FlushBlood Amylase IncreasedBlood Lactate Dehydrogenase IncreasedPneumoniaNausea
Abdominal PainVomitingHot FlushHypersensitivityDrug IneffectiveAspartate Aminotransferase IncreasedHypothyroidismOedema Peripheral
CellulitisJaundiceIncontinenceFallLipase IncreasedRespiratory Tract InfectionHysterectomyFall
Acute Lymphocytic Leukaemia RecurrentPyrexiaGraft DysfunctionCerebrovascular AccidentHypoglycaemiaAlanine Aminotransferase IncreasedIntervertebral Disc DegenerationDiarrhoea
Drug IneffectiveRenal ImpairmentDiverticulumDepressionDiplegiaMental DisorderHypertensionAbdominal Pain
Gastrointestinal DisorderPainEar PainDiverticulumWeight DecreasedDyspnoeaIrritable Bowel SyndromePain In Extremity
Feeling AbnormalHaematomaFallEar PainPancreatitisDeep Vein ThrombosisHiatus HerniaDyspnoea

Drug effectiveness by gender :

FemaleMale
Flexeril is effective50.00%
(10 of 20 people)
16.67%
(1 of 6 people)
Methotrexate is effective15.79%
(3 of 19 people)
66.67%
(4 of 6 people)

Most common drug interactions by gender * :

FemaleMale
PainArthralgia
FatiguePain
NauseaOedema Peripheral
ArthralgiaChest Pain
Oedema PeripheralFatigue
FallNausea
DiarrhoeaMuscle Spasms
Abdominal PainPain In Extremity
Bone PainDrug Ineffective
AnaemiaHypoaesthesia

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Flexeril is effectiven/an/an/an/a9.09%
(1 of 11 people)
20.00%
(2 of 10 people)
43.75%
(7 of 16 people)
25.00%
(1 of 4 people)
Methotrexate is effectiven/an/an/an/a22.22%
(2 of 9 people)
10.00%
(1 of 10 people)
21.43%
(3 of 14 people)
25.00%
(1 of 4 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/an/aAmblyopia NosHeadachePainArthralgiaFatiguePain
Asthma AggravatedNauseaDrug IneffectivePainPainArthralgia
Headache NosRheumatoid ArthritisPneumoniaOedema PeripheralAbdominal PainFatigue
Vomiting NosTachycardiaArthralgiaInjection Site PainDiarrhoeaAnaemia
VertigoGallbladder DisorderNauseaNauseaBone PainDyspnoea
DysarthriaDyspnoeaVomitingRheumatoid ArthritisNauseaFall
Tongue Disorder NosAcute Lymphocytic Leukaemia RecurrentInjection Site HaemorrhageVomitingOedema PeripheralOedema Peripheral
HypoaesthesiaSyringomyeliaWeight IncreasedHeadacheSwellingPain In Extremity
TremorVaginal HaemorrhageCoughDyspnoeaOsteoarthritisDeep Vein Thrombosis
Chorea NosParaesthesiaRashHypoaesthesiaArthralgiaHypertension

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Flexeril and Methotrexate?

Get connected! Join a related mobile support group:
- support group for people who take Flexeril and Methotrexate
- support group for people who take Flexeril
- support group for people who take Methotrexate

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More reviews for: Flexeril, Methotrexate

Complete drug side effects:

On eHealthMe, Flexeril (cyclobenzaprine hydrochloride) is often used to treat muscle spasms. Methotrexate (methotrexate sodium) is often used to treat rheumatoid arthritis. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug studies:

More related studies for: Flexeril, Methotrexate

Recent related drug comparison:

More related comparisons for: Flexeril, Methotrexate

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

 

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