Review: Flexeril and Synthroid
Summary: drug interactions are reported among people who take Flexeril and Synthroid together.
This review analyzes the effectiveness and drug interactions between Flexeril and Synthroid. It is created by eHealthMe based on reports of 2,901 people who take the same drugs from FDA and social media, and is updated regularly.
You are not alone: join a mobile support group for people who take Flexeril and Synthroid >>>
What are the drugs
Flexeril (latest outcomes from 16,437 users) has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms.
Synthroid (latest outcomes from 93,730 users) has active ingredients of levothyroxine sodium. It is often used in hypothyroidism.
On Nov, 25, 2014: 2,900 people who take Flexeril, Synthroid are studied
Drug combinations in study:
- Flexeril (cyclobenzaprine hydrochloride)
- Synthroid (levothyroxine sodium)
Drug effectiveness over time :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years||not specified|
|Flexeril is effective||27.27%|
(6 of 22 people)
(3 of 18 people)
(3 of 10 people)
(5 of 20 people)
(7 of 31 people)
(4 of 21 people)
(5 of 16 people)
(1 of 1 people)
|Synthroid is effective||0.00%|
(0 of 2 people)
(3 of 8 people)
(2 of 8 people)
(6 of 10 people)
(13 of 21 people)
(24 of 37 people)
(36 of 52 people)
Most common drug interactions over time * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years||not specified|
|Dizziness||Pain||Neutropenia||Anxiety||Depression||Depression||Deep Vein Thrombosis||Pain|
|Vomiting||Emotional Distress||Febrile Neutropenia||Pain||Anxiety||Anxiety||Pulmonary Embolism||Nausea|
|Anxiety||Injury||Pneumonia||Nausea||Suicide Attempt||Cerebrovascular Accident||Anxiety||Fall|
|Headache||Vision Blurred||Multi-organ Failure||Depression||Memory Impairment||Fatigue||Swelling||Arthralgia|
|Febrile Neutropenia||Retinal Oedema||Septic Shock||Pulmonary Embolism||Intentional Overdose||Headache||Post Thrombotic Syndrome||Back Pain|
|Neutropenia||Vomiting||Fatigue||Suicide Attempt||Loss Of Consciousness||Suicidal Ideation||Pain||Dyspnoea|
|Diarrhoea||Anxiety||Headache||Injury||Neck Pain||Thyroid Disorder||Mobility Decreased||Fatigue|
|Injury||Abdominal Pain||Hypothyroidism||Intentional Overdose||Road Traffic Accident||Dizziness||Impaired Driving Ability||Oedema Peripheral|
|Hypokalaemia||Hypothyroidism||Hypokalaemia||Cholecystitis Chronic||Bipolar Disorder||Loss Of Consciousness||Skin Discolouration||Anxiety|
|Oedema||Leukopenia||Diarrhoea||Mental Disorder||Asthenia||Numbness And Tingling||Conversion Disorder||Depression|
Drug effectiveness by gender :
|Flexeril is effective||24.62%|
(32 of 130 people)
(2 of 9 people)
|Synthroid is effective||60.47%|
(78 of 129 people)
(6 of 8 people)
Most common drug interactions by gender * :
Drug effectiveness by age :
|Flexeril is effective||n/a||n/a||n/a||10.00%|
(1 of 10 people)
(4 of 59 people)
(9 of 94 people)
(11 of 101 people)
(9 of 38 people)
|Synthroid is effective||n/a||n/a||n/a||70.00%|
(7 of 10 people)
(12 of 48 people)
(25 of 93 people)
(21 of 102 people)
(19 of 39 people)
Most common drug interactions by age * :
|n/a||n/a||Gastritis||Pulmonary Embolism||Pain||Nausea||Pain||Oedema Peripheral|
|Injury||Deep Vein Thrombosis||Anxiety||Pain||Arthralgia||Fall|
|Cholecystitis Chronic||Pain||Pulmonary Embolism||Back Pain||Nausea||Pain|
|Abdominal Pain Upper||Injury||Depression||Dizziness||Hypoaesthesia||Asthenia|
|Abdominal Pain||Anxiety||Nausea||Dyspnoea||Fatigue||Back Pain|
|Lip Swelling||Headache||Injury||Vomiting||Chest Pain||Arthralgia|
|Rheumatoid Arthritis||Vomiting||Deep Vein Thrombosis||Chest Pain||Anxiety||Pneumonia|
|Loss Of Consciousness||Diabetes Mellitus||Type 2 Diabetes Mellitus||Oedema Peripheral||Fall||Fatigue|
* Some reports may have incomplete information.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
Do you take Flexeril and Synthroid?
- Personalize this study to your gender and age
- Write a review: share your experience of taking Flexeril and Synthroid
- Ask a question: ask patients like you a question
- Subscribe the study: get notified of updates
- Post a comment: or see what other people said about the study
You are not alone! Join a related mobile support group:
- support group for people who take Flexeril and Synthroid
- support group for people who take Flexeril
- support group for people who take Synthroid
Can you answer these questions (Ask a question):
- Could fenofibrate cause extreme vaginal irritation?
(Asked by a 72 year old woman who has Itching,burning Of External Vaginal Area., and takes Levothyroxine Sodium, Fenofibrate)
might possibly be pre-diabetic...Dr checks blood sugar every 6 mo.
- Hallucinations and skin thas red and hurts
(Asked by a 46 year old woman who has Hallucinations.skin Thats Red Like A Sun Burn And Mouth Blisters, and takes Hydrochlorothiazide, Sudafed, Levothyroxine Thyroid)
I am having horrable hallucinations.manic episodes because i slam on the brakes to avoid people or animals that are not there.i feel like im going to razy.high bood pressure, heavy breathing and anxiety.my face and body have spoys that are like a sun burn and blisters in my mouth.emergency room accu ...
- Is it okay to take co enzyme q 10 with levothyroxine
(Asked by a 66 year old woman who has Hypothyroidism, and takes Levothyroxine Sodium)
Is it okay to take Co Enzyme Q10 with Lovothyroxine. Will it stop my Levothyroxine from working properly. I am also on Simvastaton. Would appreciate any advice on this.
- Why would i get copd since i never smoked?
(Asked by a 62 year old woman who has Rheumatoid Arthritis, PBC, AIH, Asthma, and takes Vitamin D, Calcium Carbonate, Anturol, Morphine Sulfate, Levothyroxine Sodium, Pyridium, Cyclobenzaprine Hydrochloride, Azathioprine, Proair Hfa, Advair Diskus 250/50, Combivent)
I have several autoimmune disorders, I was shocked to get the COPD diagnosis since I have never smoked but I had second hand smoke first 23 years of my life. My doctor said my Autoimmune Hepatitis and Primary Biliary Cholingitis set me up for COPD.
- Have you taken levothyroxine and noticed a ringing in your eyes after taking the medication.
(Asked by a 66 year old man who has Tinnitus, and takes Levothyroxine Sodium)
Never had ringing before taking Levothyroxine for thyroid problem.If you have experienced the same please respond when and if you had the same.Thanks
You may be interested at these reviews (Write a review):
- Synthroid and breast enlargement
(Posted by a 61 year old woman who has Breast Swelling, Breast Enlargement, and takes Synthroid)
I have went from a B-C cup size to a D cup in the past 8-9 months.
- Double vision on levothyroxine
(Posted by a 49 year old woman who has Joint Stiffness, Lack Of Strength, Muscle Weakness, Weakness, Itching, Allergy To Food, Allergy To Chemicals, Fatigue - Chronic, Confusional State, Hair Loss, Double Vision, and takes Levothyroxine Sodium)
Diagnosed with under active thyroid in January 2011. Noticed onset of double vision in January 2014. Blurred vision and double vision worsened to such an extent that my glasses prescription has changed three times in less than 7 months. All the symptons I experience are a direct result of taking Le ...
- I switched to armour ,it's not synthetic.
(Posted by a 72 year old woman who has Hashimotos Hypothroidism, and takes Synthroid)
I went off after 7 years on it when I discovered a link to a higher rate of lung cancer. I switched to Armour and it handled the hypothyroidism way better. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765368/
- High blood pressure - find the right medication
(Posted by a 55 year old woman who has Graves Disease, Essential High Blood Pressure, and takes Lisinopril, Losartan, Amlodipine, Levothyroxine Sodium)
I was going through the menopause with all the usual drama when I started feeling awful. Doc said that my blood pressure was through the roof and prescribed Lisinopril. This gave me technicolour dreams and a runny nose, so he switched me to Losartan. This made me soooo tired that I didn't want to ...
- Shortness of breath after taking levothyroxine for 8-10 yrs.
(Posted by a 38 year old woman who has Hypothyroidism, and takes Levothyroxine Sodium)
I have been experiencing shortness of breath lately when taking the levothyroxine. If I stop taking it for a couple of days my shortness of breath is pretty much gone.
Complete drug side effects:
On eHealthMe, Flexeril (cyclobenzaprine hydrochloride) is often used to treat muscle spasms. Synthroid (levothyroxine sodium) is often used to treat hypothyroidism. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.
What is the drug used for and how effective is it:
- Flexeril is used in:
- Synthroid is used in:
Other drugs that are used to treat the same conditions:
- Flexeril alternatives:
- Synthroid alternatives:
Recent related drug studies (Check your drugs):
- A study of drug interactions between Phenergan, Bactrim, Gabapentin, Wellbutrin Xl, Synthroid, Topamax, Prozac for a patient with Nausea, Urinary Tract Infection Enterococcal, Neuropathic Pain, Migraine - Common, Hypothyroidism, Depression. The patient has Muscle Rigidity
Comments: Just started Prozac 4 weeks ago with no side effects. Became ill with UTI, doctor prescribed Bactrim & Phenergan. Within a day, I had severe muscle rigidity in my jaw, neck, shoulders & abdomen. It was not like a "leg cramp" and nothing I have ever experienced. I stopped taking the Prozac and th ...
- A study of drug interactions between Synthroid, Lumigan for a patient with Thyroid Stimulating Hormone-producing Pituitary Tumour, Pressure Sore. The patient has Sleeping Sickness
Comments: Can hardly stay awake. Fall asleep after being awake from 2 hour naps within an hour. After running/walking on treadmill (difficult) at 2.5 mph for one half hour crawl back into bed and sleep! Not usual! Use only one drop in each eye per evening only. Sleep more than the cat! Wondered if I was h ...
- A study of side effects of Levothyroxine Sodium for a patient with Hypothyroidism. The patient has Sleep Disorder Due To A General Medical Condition
Comments: Severe stabbing pain between shoulders slightly to the right. Only lasts upto a minute. Attacks infrequent. Tartar on teeth. Sweating and chill although usually very cold. Lethargic Difficult to maintain weight. Skips meals everyday - habitually only eat dinner in the evening and have done ...
- A study of drug interactions between Metoprolol Succinate, Atorvastatin Calcium, Levothyroxine Thyroid, Arava for a patient with Blood Pressure, Lower Cholesterol, Thyroid Disorder, Rheumatoid Arthritis. The patient has Hiv Test Positive
Comments: Also take Aspirin 81 mg daily
- A study of drug interactions between Penicillin, Albuterol, Ambien, Zoloft, Propranolol Hydrochloride, Levothyroxine Thyroid for a patient with Otitis Externa, Asthma, Insomnia Related To Another Mental Condition, Anxiety Disorder Due To A General Medical Condition, Graves Disease. The patient has Pain - Shoulder, Neck Pain, Face Pain Around Ear, Neutropenia, Pressure-related Ear Pain, Ear Pain Both Sides, General Ill Feeling, Chills, Otitis Externa
Comments: A few years back I had medication induced neutropnia due to bactrim. I started getting symptoms in ear.. I had external otitis. I'm having the same symptoms
NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.