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Review: taking Fluoxetine and Subutex together

Summary: drug interactions are reported among people who take Fluoxetine and Subutex together.

This review analyzes the effectiveness and drug interactions between Fluoxetine and Subutex. It is created by eHealthMe based on reports of 118 people who take the same drugs from FDA and social media, and is updated regularly.





You are not alone: join a mobile support group for people who take Fluoxetine and Subutex >>>

What are the drugs

Fluoxetine hydrochloride has active ingredients of fluoxetine hydrochloride. It is often used in depression. (latest outcomes from 4,225 Fluoxetine hydrochloride users)

Subutex has active ingredients of buprenorphine hydrochloride. It is often used in opiate withdrawal. (latest outcomes from 3,066 Subutex users)

On Mar, 5, 2015: 118 people who take Fluoxetine Hydrochloride, Subutex are studied

Fluoxetine Hydrochloride, Subutex outcomes

Drug combinations in study:
- Fluoxetine Hydrochloride (fluoxetine hydrochloride)
- Subutex (buprenorphine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Fluoxetine Hydrochloride is effective100.00%
(1 of 1 people)
(0 of 3 people)
(0 of 1 people)
(0 of 3 people)
(1 of 2 people)
(0 of 1 people)
Subutex is effective66.67%
(2 of 3 people)
(1 of 1 people)
(3 of 3 people)
(2 of 3 people)
(1 of 1 people)
(1 of 1 people)

Drug effectiveness by gender :

Fluoxetine Hydrochloride is effective16.67%
(1 of 6 people)
(1 of 5 people)
Subutex is effective71.43%
(5 of 7 people)
(5 of 5 people)

Drug effectiveness by age :

Fluoxetine Hydrochloride is effectiven/an/a0.00%
(0 of 2 people)
(0 of 3 people)
(1 of 10 people)
(1 of 2 people)
(0 of 1 people)
Subutex is effectiven/an/a50.00%
(1 of 2 people)
(2 of 4 people)
(4 of 10 people)
(2 of 2 people)
(1 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
FatigueHyponatraemiaDysmorphismHypoglycaemiaHepatic Enzyme IncreasedThrombocytopeniaDepressionSomnolence
Energy IncreasedEndocarditis StaphylococcalSyndactylyDrug Exposure During PregnancyHepatitisPneumonia Aspiration
Drug Withdrawal SyndromeCoagulopathyDrug Exposure During PregnancyAbortion SpontaneousJaundiceDrug Exposure During Pregnancy
Disturbance In AttentionMelaenaCongenital Foot MalformationAdrenal InsufficiencyInjury
Feeling Of DespairPancytopeniaAbortion InducedWeight Loss - UnintentionalNausea
Memory ImpairmentRenal FailureAbdominal CrampsVomiting
Weight DecreasedPurpuraAppetite - DecreasedAccidental Overdose
Suicidal IdeationBone Marrow FailureExhaustion, Fatigue, Lethargy, Tiredness, WearinessAnxiety
Musculoskeletal PainPulmonary EmbolismConstipationDrug Withdrawal Syndrome Neonatal

Most common drug interactions by gender * :

Pneumonia AspirationPancytopenia
AnxietyPulmonary Embolism
Drug Exposure During PregnancyHyponatraemia
Foot DeformityRespiratory Arrest
Musculoskeletal PainBone Marrow Failure
Abdominal PainCoagulopathy
DyspnoeaEndocarditis Staphylococcal
Intervertebral Disc ProtrusionPurpura

Most common drug interactions by age * :

Drug Withdrawal Syndrome Neonataln/aHypotonia NeonatalFallThrombocytopeniaConfusional StateInsomniaPneumonia Aspiration
Anaemia NeonatalNeonatal Respiratory DepressionLoss Of Consciousness NecMelaenaOverdosePain In ExtremitySomnolence
Neutropenia NeonatalDrug Withdrawal Syndrome NeonatalMyoclonic JerksPancytopeniaAccidentDiarrhoeaToxicoderma
Complications Of Maternal Exposure To Therapeutic DrugsCyanosis NeonatalDrug MaladministrationPulmonary EmbolismInjuryUrinary RetentionAgranulocytosis
Gastro-oesophageal Reflux DiseaseApgar Score LowAbdominal Pain NosHyponatraemiaCoronary Artery AtherosclerosisMetastases To LiverDermatitis
HepatomegalySuicide AttemptRespiratory ArrestDrug AbuserProteinuria
Neonatal Disorder NosConvulsions NosBone Marrow FailureInternational Normalised Ratio IncreasedEpistaxis
Hypotonia NeonatalSuicidal IdeationCoagulopathyCardiac DisorderChest Wall Mass
Neonatal Respiratory Distress SyndromeJaundice NosEndocarditis StaphylococcalRenal ArteritisDeformity
Drug Exposure During PregnancyDrug Exposure During PregnancyAbortion InducedElectrocardiogram St Segment DepressionOdynophagia

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of Fluoxetine and Subutex on

Do you take Fluoxetine and Subutex?

You are not alone! Join a related mobile support group on :
- support group for people who take Fluoxetine Hydrochloride
- support group for people who take Subutex

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Fluoxetine Hydrochloride (fluoxetine hydrochloride) is often used to treat depression. Subutex (buprenorphine hydrochloride) is often used to treat opiate withdrawal. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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