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Review: taking Fosamax and Cymbalta together

Summary: drug interactions are reported among people who take Fosamax and Cymbalta together.

This review analyzes the effectiveness and drug interactions between Fosamax and Cymbalta. It is created by eHealthMe based on reports of 729 people who take the same drugs from FDA and social media, and is updated regularly.


You are not alone: join a support group for people who take Fosamax and Cymbalta >>>

On Apr, 13, 2015: 729 people who take Fosamax, Cymbalta are studied

Fosamax, Cymbalta outcomes

Drug combinations in study:
- Fosamax (alendronate sodium)
- Cymbalta (duloxetine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Fosamax is effective0.00%
(0 of 1 people)
(0 of 2 people)
(0 of 2 people)
(0 of 2 people)
Cymbalta is effectiven/a0.00%
(0 of 2 people)
(1 of 4 people)
(0 of 1 people)
(1 of 2 people)
(1 of 1 people)

Drug effectiveness by gender :

Fosamax is effective0.00%
(0 of 6 people)
(0 of 1 people)
Cymbalta is effective37.50%
(3 of 8 people)
(0 of 1 people)

Drug effectiveness by age :

Fosamax is effectiven/an/an/a0.00%
(0 of 1 people)
(0 of 1 people)
(0 of 2 people)
(0 of 4 people)
Cymbalta is effectiven/an/an/a100.00%
(1 of 1 people)
(0 of 1 people)
(1 of 3 people)
(1 of 7 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
FallImpaired HealingHypertensionArthralgiaFemur FractureFemur FractureFemur FracturePain
Gastrooesophageal Reflux DiseaseGastrooesophageal Reflux DiseaseFallFemur FracturePain In ExtremityOsteoarthritisColon AdenomaAnxiety
PainOsteomyelitisNauseaGastrooesophageal Reflux DiseaseGastrooesophageal Reflux DiseaseLow Turnover OsteopathyCystitisFall
NauseaDental CariesVomitingBone Density DecreasedImpaired HealingHypothyroidismHypothyroidismNausea
ConstipationBursitisSynovial CystPainArthralgiaGastrointestinal DisorderUterine LeiomyomaDepression
ArthritisOsteonecrosis Of JawPain In ExtremityPain In ExtremityAnxietyGastrooesophageal Reflux DiseaseOvarian CystPain In Extremity
AnxietyPalpitationsArthralgiaDrug IneffectiveFoot FractureAnxietyTooth DisorderOsteonecrosis Of Jaw
Bone DisorderFallTooth FractureArthritisOsteonecrosis Of JawConstipationPostmenopausal HaemorrhageBack Pain
Abdominal Pain UpperNauseaDental CariesOedema PeripheralDental CariesCystitisLymphoedemaConstipation

Most common drug interactions by gender * :

AnxietyWeight Decreased
DepressionAbdominal Pain
Pain In ExtremityAtrial Fibrillation
Osteonecrosis Of JawFall
Back PainBack Pain
Cardiac Failure CongestiveNausea

Most common drug interactions by age * :

n/an/an/aNeoplasm MalignantHypothyroidismPainAnxietyFall
Polymorphic Light EruptionSwellingNauseaPainPain
RashKidney InfectionHypertensionOsteonecrosis Of JawNausea
Mycosis FungoidesPolymyositisAnxietyAnhedoniaAnxiety
PruritusOsteomyelitisHypoaesthesiaPain In ExtremityPain In Extremity
HypotensionFatigueEmotional DistressTooth DisorderBack Pain
Infusion Related ReactionPancreatitisVomitingImpaired HealingDepression
MigraineHepatic SteatosisInfectionDiarrhoeaOsteomyelitis
ConvulsionWeight DecreasedArthralgiaNauseaAnaemia
VomitingThyroid NeoplasmFallArthralgia

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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You are not alone! Join a related support group:
- support group for people who take Cymbalta
- support group for people who take Fosamax

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Fosamax (alendronate sodium) is often used to treat osteoporosis. Cymbalta (duloxetine hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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