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Review: Gabapentin and Benadryl





Summary: drug interactions are reported among people who take Gabapentin and Benadryl together.

This review analyzes the effectiveness and drug interactions between Gabapentin and Benadryl. It is created by eHealthMe based on reports of 1,926 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Gabapentin and Benadryl >>>

What are the drugs

Gabapentin has active ingredients of gabapentin. It is often used in neuralgia. (latest outcomes from Gabapentin 39,518 users)

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in allergies. (view latest outcomes from 29,367 users)

On Nov, 25, 2014: 1,925 people who take Gabapentin, Benadryl are studied

Gabapentin, Benadryl outcomes

Drug combinations in study:
- Gabapentin (gabapentin)
- Benadryl (diphenhydramine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Gabapentin is effective40.00%
(2 of 5 people)
30.00%
(3 of 10 people)
33.33%
(2 of 6 people)
33.33%
(3 of 9 people)
25.00%
(3 of 12 people)
75.00%
(3 of 4 people)
50.00%
(1 of 2 people)
0.00%
(0 of 2 people)
Benadryl is effective16.67%
(2 of 12 people)
20.00%
(1 of 5 people)
100.00%
(4 of 4 people)
50.00%
(3 of 6 people)
66.67%
(4 of 6 people)
71.43%
(5 of 7 people)
83.33%
(5 of 6 people)
50.00%
(1 of 2 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
HypotensionPneumonitisAppendicitisComaConfusional StateSleep DisorderNeck TightnessPain
FatigueHypernatraemiaDiabetic NeuropathyDrug IneffectiveOliguriaDrug IneffectivePalpitationsAnxiety
Pain In ExtremityPneumonia Respiratory Syncytial ViralDiabetic FootHepatic FailureHepatic FailureHepatitis BLightheadednessNausea
Aspartate Aminotransferase IncreasedAcute Respiratory Distress SyndromeDiabetes Mellitus Inadequate ControlSuicide AttemptMultiple Drug OverdoseHepatitis CMuscle SpasmsArthralgia
Renal Failure AcuteHypotensionBlood Cholesterol IncreasedOliguriaComaFeeling AbnormalBack Pain
Deep Vein ThrombosisBlood Bilirubin IncreasedGlucose Tolerance ImpairedAmnesiaSuicide AttemptHepatitis APain In Extremity
Platelet Count DecreasedBreast CancerObesityAppendicitisBlood Creatinine IncreasedInfluenzaDyspnoea
DehydrationDuodenal Ulcer PerforationRoad Traffic AccidentBlood Creatinine IncreasedHypoglycaemiaHaemorrhoidsAnaemia
Alanine Aminotransferase IncreasedRespiratory FailureNephrogenic Fibrosing DermopathyHypoglycaemiaAmnesiaPneumoniaVomiting
AnaemiaInterstitial Lung DiseaseHypoxiaMultiple Drug OverdoseDrug IneffectiveWeight DecreasedOsteonecrosis Of Jaw

Drug effectiveness by gender :

FemaleMale
Gabapentin is effective31.43%
(11 of 35 people)
42.86%
(6 of 14 people)
Benadryl is effective54.29%
(19 of 35 people)
46.15%
(6 of 13 people)

Most common drug interactions by gender * :

FemaleMale
PainPain
ArthralgiaAnxiety
AnxietyNausea
NauseaPain In Extremity
DyspnoeaBack Pain
Pain In ExtremityDepression
Back PainArthralgia
AnaemiaVomiting
Osteonecrosis Of JawHeadache
FatigueAnaemia

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Gabapentin is effectiven/an/an/a22.22%
(2 of 9 people)
10.00%
(3 of 30 people)
16.67%
(3 of 18 people)
37.50%
(6 of 16 people)
14.29%
(3 of 21 people)
Benadryl is effectiven/an/an/a20.00%
(2 of 10 people)
23.33%
(7 of 30 people)
25.00%
(4 of 16 people)
40.00%
(6 of 15 people)
31.58%
(6 of 19 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Orthostatic HypotensionGastrointestinal Mucosal ExfoliationNephrogenic Systemic FibrosisPainPainPainPainFall
StillbirthHaematocheziaPainDyspnoeaAnxietyAnxietyAnxietyFatigue
Umbilical Cord Around NeckDiarrhoea HaemorrhagicPain In ExtremityNauseaHeadacheBack PainPain In ExtremityAnaemia
Urinary Tract InfectionUlcer HaemorrhageCardiac ArrestLung DisorderPyrexiaDiarrhoeaNauseaPain
Type 2 Diabetes MellitusPneumatosis IntestinalisHypotensionLymphadenopathyDiarrhoeaHeadacheArthralgiaPain In Extremity
NephrolithiasisMalignant Neoplasm ProgressionPyrexiaTachycardiaVomitingPain In ExtremityInjuryOsteoarthritis
Pericardial EffusionNeuroblastomaMetaplasiaSynovial CystParaesthesiaNauseaHypoaesthesiaNausea
Pulmonary HypertensionContusionSkin IndurationArthralgiaHallucinationArthralgiaDyspnoeaDyspnoea
SepsisSkin TightnessNeuropathy PeripheralDyspnoeaVomitingOsteoarthritisBack Pain
Chest PainPulmonary FibrosisOral HerpesSuicidal IdeationAnaemiaEmotional DistressOsteonecrosis Of Jaw

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Gabapentin and Benadryl?

You are not alone! Join a related mobile support group:
- support group for people who take Gabapentin and Benadryl
- support group for people who take Benadryl
- support group for people who take Gabapentin

Can you answer these questions (Ask a question):

More questions for: Benadryl, Gabapentin

You may be interested at these reviews (Write a review):

  • Dyphenhydramine and headaches horrible going one almost 24 hours a day for 4 weeks and cant get them to stop, now looking for cause . think its the dyphenhydramine im taking to help me sleep .
    have been taking 3 dyphenhydramine for some time to help me sleep , just in last few weeks began having severe headache almost all the time.. cant get it to go away. just found out it can cause headache and am going to lower my intake to one per night and see if my headaches get better. am taking migrane meds and that hasnt helped a bit so think its not migranes im having. some other reason.
  • Ranexa and erectile dysfunction
    I have experienced moderate ED with taking multiple heart and NO meds. This has been manageable and acceptable. Cardiologist added Ranexa (Ranalozine) 3 weeks ago and I am now experiencing complete erectile and ejaculatory failure.
  • Cough and gabapentin
    Have chronic cough for 6 yr's at least.3 yr's ago it got bad enough to seek doc. Help. Took all the tests . Tried to tell me I had asthma,copd, ect. Put me on sprivia, symbicort, singular, helped a little for awhile. Long story short. Went to one doc. He asked me some questions about my cough. Figured out it usually started with a tickle on the left side of my throat. And he put me on gabapentin 300mg. 3 times Aday. Which is for nerve damage. It took about 7days to see some change. And about 35days To stop the chronic cough. I still cough once in awhile. But no chronic coughing. Now I am going to try and see if I can stop the other med,s one at a time and see what happens
  • Nightmare on benadryl
    After 5 nights without sleep and not having past bad dreams, the last 2 night's taking walfrin sub, for benadryl has terrified THE WORST OF WORST dream in my 55 years. Peaceful start of a dream then seeing myself or family,friends get slottard.crazy thing is I don't watch scary movies or the news. I think I'm going to pass on this meds, and pass out next time :) thank you,God bless
  • Benadryl completed suicide 50 year old
    My mother comitted suicide by taking a bottle of Benadryl. She also had been drinking, she had taken xanax and drank beer, she also took 300 Benadryl pills and started having seizures and went to the hospital was brain dead and her heart stopped the next morning.

More reviews for: Benadryl, Gabapentin

Comments from related studies:

  • From this study (9 months ago):

  • Been I'll for 9 months. Just recently found pneumonia. Can't afford dermatologist and do for doesn't know what the hives are. You can write with your finger on my skin and it will show up.

    Reply

  • From this study (1 year ago):

  • I've lost 70 lbs in two years, 40 lbs. in the past year. I am having significant atrophy in my legs, specifically my right leg. As a 52 year old man, I cannot walk normally nor can I walk up stairs.

    Reply

  • From this study (1 year ago):

  • To ER with new onset pressure/tightness in throat/neck up to my ears. Have a paraesophageal hiatal hernia. Cardiac work up negative. New bradycardia, low of mid 50's) with this episode. Normal HR is 80's +/- 10.

    Reply

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Complete drug side effects:

On eHealthMe, Gabapentin (gabapentin) is often used to treat neuralgia. Benadryl (diphenhydramine hydrochloride) is often used to treat allergies. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

   

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