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Review: Gabapentin and Benadryl

This review analyzes the effectiveness and drug interactions between Gabapentin and Benadryl. It is created by eHealthMe based on 1,863 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

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On Apr, 1, 2014: 1,863 people who reported to have interactions when taking Gabapentin, Benadryl are studied

Trend of Gabapentin, Benadryl's drug interactions, side effects and effectiveness reports (8525343)

Drug combinations in study:
- Gabapentin (gabapentin)
- Benadryl (diphenhydramine hydrochloride)

eHealthMe real world results:

Most common interactions experienced by people in the use of Gabapentin, Benadryl:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Anxiety1,462
Arthralgia (joint pain)1,320
Pain1,313
Dyspnoea (difficult or laboured respiration)1,309
Vomiting1,165
Nausea (feeling of having an urge to vomit)913
Back Pain855
Osteonecrosis Of Jaw (death of bone of jaw)838
Pain In Extremity824
Anaemia (lack of blood)816

Most common interactions experienced by people in long term use of Gabapentin, Benadryl:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Drug Ineffective26
Oliguria (not enough urine)18
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)18
Hypoglycaemia (deficiency of glucose in the bloodstream)18
Coma (state of unconsciousness lasting more than six hours)18
Hepatic Failure (liver failure)16
Confusional State12
Blood Creatinine Increased12
Multiple Drug Overdose12
Suicide Attempt12

How effective are the drugs:

not at allsomewhatmoderatehighvery high
Gabapentin0.00%12.50%37.50%37.50%12.50%
Benadryl0.00%33.33%0.00%50.00%16.67%

Top conditions involved for these people * :

  1. Pain
  2. Premedication
  3. Depression
  4. Prophylaxis
  5. Hypertension

Top co-used drugs for these people * :

  1. Neurontin
  2. Seroquel
  3. Heparin sodium injection
  4. Aspirin
  5. Diphenhydramine hcl

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Benadryl, Gabapentin

You can also:

Complete drug side effects:

On eHealthMe, Gabapentin (gabapentin) is often used to treat neuralgia. Benadryl (diphenhydramine hydrochloride) is often used to treat allergies. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Comments from related studies:

  • From this study (5 days ago):

  • Been I'll for 9 months. Just recently found pneumonia. Can't afford dermatologist and do for doesn't know what the hives are. You can write with your finger on my skin and it will show up.

    Reply

  • From this study (6 months ago):

  • I've lost 70 lbs in two years, 40 lbs. in the past year. I am having significant atrophy in my legs, specifically my right leg. As a 52 year old man, I cannot walk normally nor can I walk up stairs.

    Reply

  • From this study (8 months ago):

  • To ER with new onset pressure/tightness in throat/neck up to my ears. Have a paraesophageal hiatal hernia. Cardiac work up negative. New bradycardia, low of mid 50's) with this episode. Normal HR is 80's +/- 10.

    Reply

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More questions for: Benadryl, Gabapentin

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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