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Review: taking Percocet and Gabapentin together

Summary: drug interactions are reported among people who take Percocet and Gabapentin together.

This review analyzes the effectiveness and drug interactions between Percocet and Gabapentin. It is created by eHealthMe based on reports of 4,271 people who take the same drugs from FDA and social media, and is updated regularly.


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On Mar, 1, 2015: 4,271 people who take Percocet, Gabapentin are studied

Percocet, Gabapentin outcomes

Drug combinations in study:
- Percocet (acetaminophen; oxycodone hydrochloride)
- Gabapentin (gabapentin)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Percocet is effective14.29%
(3 of 21 people)
(17 of 45 people)
(6 of 15 people)
(10 of 33 people)
(17 of 38 people)
(4 of 12 people)
(2 of 5 people)
(1 of 2 people)
Gabapentin is effective14.29%
(5 of 35 people)
(4 of 39 people)
(4 of 15 people)
(6 of 23 people)
(6 of 29 people)
(2 of 13 people)
(4 of 11 people)

Drug effectiveness by gender :

Percocet is effective34.51%
(39 of 113 people)
(21 of 58 people)
Gabapentin is effective20.00%
(21 of 105 people)
(9 of 57 people)

Drug effectiveness by age :

Percocet is effectiven/an/an/a28.57%
(10 of 35 people)
(15 of 82 people)
(15 of 75 people)
(12 of 62 people)
(8 of 40 people)
Gabapentin is effectiven/an/an/a6.25%
(2 of 32 people)
(5 of 80 people)
(8 of 80 people)
(10 of 63 people)
(6 of 40 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
PainDepressionBack PainDrug IneffectivePainMyocardial InfarctionAnxietyPain
NauseaHypertensionHypertensionPainDepressionAnxietyChronic PainAnxiety
DizzinessAnxietyAnaemiaCompleted SuicideAnxietyCerebrovascular AccidentSleep Disorder Due To General Medical Condition, Insomnia TypeNausea
FallDrug IneffectiveErythemaMulti-organ FailureSuicidal IdeationHypoaesthesiaBipolar DisorderBack Pain
HeadachePainLung NeoplasmDepressionBack PainSwellingFeverDepression
Drug IneffectiveFatigueKyphosisArteriosclerosisMood SwingsHypertensionDepression AggravatedDyspnoea
Weight IncreasedNauseaMuscle SwellingHypertensionArthralgiaGastrooesophageal Reflux DiseaseFatigueFatigue
Back PainConfusional StateOsteonecrosis Of JawCardiac ArrestDrug IneffectivePainJoint PainAnaemia
InsomniaDrug DependencePollakiuriaMyocardial InfarctionAngerDepressionMuscle PainOsteonecrosis Of Jaw
SomnolenceGait DisturbancePain In JawNauseaDrug DependenceAnaemiaLower Extremity MassPain In Extremity

Most common drug interactions by gender * :

Back PainBack Pain
FallOsteonecrosis Of Jaw
Pain In ExtremityAnaemia

Most common drug interactions by age * :

Tricuspid Valve DiseasePainPainDyspnoeaDepressionPainPainPain
Ventricular Septal DefectOtitis MediaIleusVomitingPainNauseaAnxietyAnxiety
Drug Exposure During PregnancySkin InfectionHyponatraemiaDepressionHeadacheAnxietyAnaemiaFall
Cardiac AneurysmDevice Related InfectionNauseaAnxietyAnxietyDepressionBack PainBack Pain
Pericardial EffusionPneumoniaFebrile NeutropeniaPainNauseaArthralgiaNauseaAnaemia
JaundiceFeeding Tube ComplicationVomitingNauseaHypoaesthesiaHeadacheFatigueBone Disorder
NephrolithiasisVomitingAbdominal DistensionCholecystitis ChronicDrug IneffectiveInsomniaOsteonecrosis Of JawNausea
Cardiac PerforationDrug Level IncreasedPneumoniaAbdominal PainDyspnoeaBack PainOedema PeripheralDyspnoea
Skull MalformationConvulsionFatigueAsthmaArthralgiaFatigueArthralgiaAsthenia
Jaundice NeonatalDrug Withdrawal SyndromeDehydrationSuicidal IdeationDizzinessDyspnoeaConstipationOsteonecrosis Of Jaw

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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- support group for people who take Gabapentin
- support group for people who take Percocet

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Percocet (acetaminophen; oxycodone hydrochloride) is often used to treat pain. Gabapentin (gabapentin) is often used to treat neuralgia. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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