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Review: Gabapentin and Savella

This review analyzes the effectiveness and drug interactions between Gabapentin and Savella. It is created by eHealthMe based on reports of 263 people who take the same drugs from FDA and social media, and is updated regularly.

Get connected: join a mobile support group for people who take Gabapentin and Savella >>>

What are the drugs

Gabapentin (latest outcomes from 39,418 users) has active ingredients of gabapentin. It is often used in pain.

Savella (latest outcomes from 3,383 users) has active ingredients of milnacipran hydrochloride. It is often used in fibromyalgia.

On Sep, 26, 2014: 263 people who take Gabapentin, Savella are studied

Gabapentin, Savella outcomes

Drug combinations in study:
- Gabapentin (gabapentin)
- Savella (milnacipran hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Gabapentin is effective100.00%
(1 of 1 people)
25.00%
(2 of 8 people)
0.00%
(0 of 2 people)
40.00%
(2 of 5 people)
27.27%
(3 of 11 people)
33.33%
(1 of 3 people)
n/an/a
Savella is effective50.00%
(1 of 2 people)
0.00%
(0 of 12 people)
20.00%
(1 of 5 people)
60.00%
(3 of 5 people)
100.00%
(3 of 3 people)
n/an/an/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
FatigueNauseaUrinary RetentionPainFibromyalgiaDrug Ineffectiven/aFatigue
AgitationHypertensionMuscle FatigueSuicidal IdeationFacet Joint SyndromeDry MouthPain
NauseaExhaustion, Fatigue, Lethargy, Tiredness, WearinessCervicogenic HeadacheCardiac DisorderBack Pain - LowFatigueNausea
HyperhidrosisPancreatitis AcuteHigh Blood PressureDrug IneffectiveHigh Blood Cholesterol And TriglyceridesPainHeadache
InsomniaAbnormal DreamsStevens-johnson SyndromeSomnolenceHypertensionDecreased AppetiteAgitation
HeadacheDiastolic DysfunctionPancreatitisNauseaDepressionDepression AggravatedInsomnia
DiarrhoeaFatigueExhaustion, Fatigue, Lethargy, Tiredness, WearinessLoss Of ConsciousnessMigraineNausea AggravatedDrug Ineffective
IrritabilityDecreased AppetiteTinnitusMusculoskeletal StiffnessGerdIbsVomiting
PalpitationsNeck PainNeuromaMalaiseUrinary RetentionMiddle InsomniaMalaise
Drug IneffectiveVentricular HypertrophySkin PlaqueTremorVomitingIrritability

Drug effectiveness by gender :

FemaleMale
Gabapentin is effective29.63%
(8 of 27 people)
33.33%
(1 of 3 people)
Savella is effective33.33%
(8 of 24 people)
0.00%
(0 of 3 people)

Most common drug interactions by gender * :

FemaleMale
FatigueArthralgia
NauseaPain In Extremity
PainDry Mouth
HeadachePain
InsomniaParaesthesia
AgitationRed Blood Cell Sedimentation Rate Increased
Drug IneffectiveDrug Ineffective
VomitingMobility Decreased
DiarrhoeaAntinuclear Antibody Increased
MalaiseWeight Decreased

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Gabapentin is effectiven/an/an/a0.00%
(0 of 6 people)
10.00%
(1 of 10 people)
12.12%
(4 of 33 people)
25.00%
(1 of 4 people)
37.50%
(3 of 8 people)
Savella is effectiven/an/an/a16.67%
(1 of 6 people)
20.00%
(2 of 10 people)
9.38%
(3 of 32 people)
0.00%
(0 of 2 people)
25.00%
(2 of 8 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/an/aHypertensionDeep Vein ThrombosisTachycardiaNauseaFatigueHeadache
FatigueNauseaCellulitisPainNauseaInsomnia
RashDiarrhoeaHyperhidrosisAgitationHeadacheBurning Sensation
FlushingVomitingExhaustion, Fatigue, Lethargy, Tiredness, WearinessDecreased AppetiteHeart Rate IncreasedFatigue
Lupus-like SyndromeRashNauseaMigraineMalaiseDiarrhoea
PainLoss Of ConsciousnessFallDyspnoeaAgitation
InjuryInjuryArthralgiaPainPain
Back Pain - LowDyspnoeaHeadacheSuicidal IdeationDyskinesia
Myofascial Pain SyndromePulmonary EmbolismVomitingHot FlushNightmare
GerdJoint SwellingPyrexiaPalpitationsAnxiety

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Gabapentin and Savella?

Get connected! Join a mobile support group:
- group for people who take Gabapentin and Savella
- group for people who take Gabapentin
- group for people who take Savella

Comments from related studies:

  • From this study (6 months ago):

  • diagnosis of fibromyalgia x 2 years ago
    diagnosis of breast cancer 3 mos ago . No longer taking estrogen progesterone Blood pressure has begun to rise approx 3 mos ago.

    Reply

  • From this study (11 months ago):

  • I have become increasingly obsessive. I was switched to generic Geodon and it was not working. I have been on 60 mg of Geodon for about a month. I am feeling somewhat better ], but still worry a lot.

    Reply

  • From this study (1 year ago):

  • Please help if you are able.
    Background: Very Healthy, active 115 lb. 70 year old female. Worked out, lifted weights, 40 minute walk, 40 deep knee bends, 20 push ups, all daily activities until 8 months ago when became profoundly fatigued, with severe (incapacitating) muscle pain, literally overnight. Had to quit job, as too fatigued to work. Currently: No muscle pain. Debilitating fatigue persists.
    Current Meds:
    200 Tramadol daily, Chronic Severe Bursitis
    8 mgs. Prednisone daily, fatigue
    50 mcs. Synthroid daily, Hypothyroidism
    300 mgs. Gabapentin daily, Post Herpetic Neuralgia (Shingles)
    Savella Dose pack prescribed. Details below.

    Current Problem:
    Recently prescribed Savella dose pack to treat unremitting fatigue. Dx: PMR NOS. Also taking Tramadol 200 mgs. daily, 3 years for Severe Chronic Bursitis.
    After 12.5 msg Savella twice daily for three days, nothing different noted.
    Dose pack increase: 25 mgs twice daily for four days. After three days, noted moderate increase in energy. Dose pack increase to 50 mgs. twice daily. After three to four days felt increasingly worse: fatigued, weak, unsteady on my feet, heart rate 104 (typically 70-74). Fatigue much worse than before started Savella. Quit Savella.
    Question: I read Savella interacts badly with Tramadol, but how seriously for my body, and at what dose? Savella at lower dose (25 mgs twice daily,) was such a welcome therapeutic difference in fatigue symptoms. If possible, would like to restart Savella at 25 mgs twice daily. Would I notice if an interaction with Tramadol at that dose of Savella, and would it preclude taking them together? Looking forward to your report on others experiencing these interactions and symptoms.

    Reply

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Complete drug side effects:

On eHealthMe, Gabapentin (gabapentin) is often used to treat neuralgia. Savella (milnacipran hydrochloride) is often used to treat fibromyalgia. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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