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Review: Gabapentin and Vitamin B12





Summary: drug interactions are reported among people who take Gabapentin and Vitamin B12 together.

This review analyzes the effectiveness and drug interactions between Gabapentin and Vitamin B12. It is created by eHealthMe based on reports of 139 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Gabapentin and Vitamin B12 >>>

What are the drugs

Gabapentin has active ingredients of gabapentin. It is often used in neuralgia. (latest outcomes from Gabapentin 39,518 users)

Vitamin b12 has active ingredients of cobalamin. It is often used in vitamin b12 deficiency. (latest outcomes from Vitamin b12 2,941 users)

On Dec, 14, 2014: 139 people who take Gabapentin, Vitamin B12 are studied

Gabapentin, Vitamin B12 outcomes

Drug combinations in study:
- Gabapentin (gabapentin)
- Vitamin B12 (cobalamin)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Gabapentin is effective75.00%
(3 of 4 people)
28.57%
(4 of 14 people)
0.00%
(0 of 6 people)
25.00%
(2 of 8 people)
60.00%
(6 of 10 people)
100.00%
(2 of 2 people)
0.00%
(0 of 2 people)
n/a
Vitamin B12 is effective0.00%
(0 of 3 people)
40.00%
(2 of 5 people)
0.00%
(0 of 6 people)
42.86%
(3 of 7 people)
33.33%
(3 of 9 people)
75.00%
(3 of 4 people)
50.00%
(1 of 2 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Swelling Of The Ankles - Feet - LegsFatigueAbnormal Weight GainMigraineNeuropathyHigh Blood PressureFatigue - ChronicDrug Ineffective
Swelling Of A JointBone And Joint PainVision BlurredHigh Blood PressurePain - MusclesVitamin B12 DecreasedFeverNausea
Intractable PainBack PainCystitis-like SymptomMenopausal SymptomsExhaustion, Fatigue, Lethargy, Tiredness, WearinessNeuropathySweating FeverAsthenia
Joint PainStevens-johnson SyndromeDepressionGastroparesisGastroparesisSpinal StenosisJoint PainFall
FeverWeight DecreasedFatigueHigh Blood SugarWhite Blood Cells Urine PositiveStrokeSwelling Of The Ankles - Feet - LegsCondition Aggravated
Neuropathy - Sciatic NerveGerdHair LossInsomniaSyncopeArthritisIntractable PainDyspnoea
Pain - BackRoad Traffic AccidentStress And AnxietyHeartbeat SensationsRaynaud's PhenomenonGouty ArthritisSwelling Of A JointPneumonia
Peripheral NeuropathyMuscle TightnessPalpitationsBack PainHypothyroidismDiuretic EffectChronic PainPain
Sweating FeverPanic AttackCognitive DeteriorationAnxiety PostoperativePruritus GeneralisedNumbness And TinglingNeuropathic PainAnxiety
Fatigue - ChronicComplex Partial SeizuresIrritabilityChronic PainAccidental OverdoseButtock PainEczema EyelidsFatigue

Drug effectiveness by gender :

FemaleMale
Gabapentin is effective43.24%
(16 of 37 people)
11.11%
(1 of 9 people)
Vitamin B12 is effective35.71%
(10 of 28 people)
25.00%
(2 of 8 people)

Most common drug interactions by gender * :

FemaleMale
Drug IneffectiveFatigue
FallDrug Ineffective
Condition AggravatedDyspnoea
NauseaAsthenia
AstheniaHearing Impaired
PainBlood Pressure Increased
MyalgiaLung Neoplasm Malignant
AnxietyInsomnia
Herpes ZosterPhotopsia
Plantar FasciitisWaldenstrom's Macroglobulinaemia

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Gabapentin is effectiven/an/an/a14.29%
(1 of 7 people)
4.55%
(2 of 44 people)
9.52%
(2 of 21 people)
14.58%
(7 of 48 people)
13.89%
(5 of 36 people)
Vitamin B12 is effectiven/an/an/an/a5.26%
(2 of 38 people)
18.18%
(4 of 22 people)
6.25%
(2 of 32 people)
11.76%
(4 of 34 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/an/an/aNausea And VomitingCystitis-like SymptomPneumonia NosBack PainDrug Ineffective
Weight GainEndometriosisPruritusMyalgiaAsthenia
Yeast Infection - VaginaFatigueInjection Site PainNauseaFall
Vision BlurredAbnormal Weight GainErythemaNeuralgia NosNausea
Stomach PainMalformation VenousDrug MaladministrationAnaemiaDyspnoea
VomitingFemoroacetabular ImpingementHypothyroidismBurning Sensation NosGait Abnormal
FeverJoint StiffnessHyperkalaemiaPain NosDrug Withdrawal Syndrome
Sweating IncreasedMusculoskeletal DiscomfortCondition AggravatedLacrimation IncreasedAnxiety
Raynaud's PhenomenonSwelling FaceRheumatoid ArthritisHerpes Zoster
HypothyroidismHypersensitivity NosDysuriaDrug Dependence

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Gabapentin and Vitamin B12?

You are not alone! Join a related mobile support group:
- support group for people who take Gabapentin and Vitamin B12
- support group for people who take Gabapentin
- support group for people who take Vitamin B12

Can you answer these questions (Ask a question):

  • Can i take slophyllin with gabapentin
    I am currently taking gabapentin for spinal nerve pain but before I was prescribed this medication I used to take slophyllin for a persistent tickley cough. I want to know if it is safe to take them both.
  • Requip cause dysphagia
    an increase caused me not to be able to swallow at all
  • Does anyone else have peripheral neuropathy? anyone have pn with lichen sclerosus? i have pain in hands, feet and face.
    Pain much worse at end of day and when I overdo. Sleep difficult - but essential! Feel so much better if I get 6+ hours. At the moment, very distressed by swollen lips (mostly inside mouth) and tissue surrounding eyes. I'm sure I have some arthritis in my fingers and toes. I also have had lichen sclerosus on my skin for nearly 20 years. Have had the PN for 15 years or so. I'm afraid that the medications can actually make the condition worse. If anyone has any suggestions, I'm all ears!
  • Does nexplanon have nickel in it?
    I have a severe nickel allergy and I have epilepsy. I am considering explain to reduce periodes since my seizures are worse that time of the month. I need to know if nexplanon has nickel because I need to avoid it if it does.
  • Can gabapentin cause bladder distension? there is no urinary symptom .
    Existing illness are Chronic renal failure (after hydro uretero nephrosis due to BPH) and peripheral neuropathy (vit B6 deficiency ) after ATT are the major problems along with BP .At present , the problem is that creatinine gas risen from 1,1 to 1.5 in 6 months .Since 6 months , I am taking medicines for neuropathy so I doubt some side effect of these medicines as Ultrasound has shown bladder distension but I do not feel any urinary problem at present. I also have kidney stones but seeing the ultrasound report , doctor said it is not hindering with urine passage . I feel some tightness , fullness and protruded lower abdomen part. I am aged 72 from India and am vegetarian.I also take some drugs for controlling blood pressure . I have elevated Blood urea at present (52) . I was given medicine to relax prostrate muscles for last 20 days but I did not feel any improvement in my bladder size. I had had my prostrate operated 2 years back.

More questions for: Gabapentin, Vitamin B12

You may be interested at these reviews (Write a review):

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    Have chronic cough for 6 yr's at least.3 yr's ago it got bad enough to seek doc. Help. Took all the tests . Tried to tell me I had asthma,copd, ect. Put me on sprivia, symbicort, singular, helped a little for awhile. Long story short. Went to one doc. He asked me some questions about my cough. Figured out it usually started with a tickle on the left side of my throat. And he put me on gabapentin 300mg. 3 times Aday. Which is for nerve damage. It took about 7days to see some change. And about 35days To stop the chronic cough. I still cough once in awhile. But no chronic coughing. Now I am going to try and see if I can stop the other med,s one at a time and see what happens
  • Had nms in 2005, will trileptal increase chance of recurrence?
    In 2005 I had NMS, which was not detected by my drs for 4 months. I'd been on Lexapro & Seroquel for 2 yrs, but was weaned from Lexapro & placed on Lamictal 3/05. Began getting low-grade fevers, which I was told were not caused by the Lamictal. I quit taking it anyway, fevers (along with uncontrollable shivering) continued & got higher. By 5/05 my temps were reaching 105 deg F. Husband said I became combative, refused to go to hospital. Early June/05 he came home to find me wrapped in blankets, with a temp over 105 F. He tried to place me in a tub of cold water, said I was rigid & screamed when he tried to move me. I was in the tub, speaking "in tongues" (his description, I have no memory of this). He called 911, took me to hospital. I woke, no idea where I was or why. After a lumbar puncture & 2 days in ICU I went home. The fevers continued...2 weeks later he came home to find me wrapped in sheets, towels, blankets, with the heat on full (it was in the 90's outside) he called ambulance again. I awoke to find myself under an ice blanket with nurses pushing large vials of dantrolene into both arms, several liters. Another LP, a stint in ICU...this time they told me it was NMS. The dr who dxd me said he was surprised I was alive, & not a vegetable, as my temp had peaked at 109 deg F. I suffered brain damage; short-term memory loss, brain can't control my body temp, my blood pressure went up. An arteriogram showed completely healthy heart & arteries, no plaque at all. I lost all body fat as well as some muscle mass. The fevers continued even after stopping the Seroquel. I visited my PCP for a checkup in 9/05, temp was normal. I started shuddering, my temp went up a full degree every 5 minutes. PCP admitted me to ER, my heart rate was over 272 B/M; they stopped my heart 3 times to "reset" it, which didn't work. I spent 3 days in hospital. Several months later my P doc tried me on Lamictal alone; I got Stevens-Johnson syndrome. I stopped the drug as soon as the signs appeared. I've been untreated, except for Neurontin & Primidone, until my manic episodes became unlivable. 3 weeks ago I went 8 days with no sleep, became psychotic. My P doc gave me Trileptal, which has evened my moods, but I've been getting low-grade fevers (highest was 103.6). Would having had NMS in the past make me more prone to falling to it again with the Trileptal? It's the only new med I've taken in over a year.
  • Prescribed drugs side effect (1 response)
    I have been on these 2 drugs (Gabapentin and Baclofen) prescribed by my gp for osteoarthritis and nerve damage in my full back.Now also suffering from the grief of losing my beloved companion Harvey (dog),I was diagnosed with deep depression. I was given fluoxetine and have been taking this for almost 4 weeks (along with the other 2 meds) and today I have a very sore tongue and it has been white for a number of days,i am going to the pharmacy tomorrow to seek some advice as I am not sure I should be taking all these together? As I am on the highest dose of depression tablets with the fluoxetine I feel it is unsafe to take with the other 2 as the baclofen can also be used to treat certain types of depression. But I can not do without either and as I am allergic to codeine I am pretty much stuck.
  • Neurotin and venous insufficiency
    I have been on neurotin/gabapentin for 8 years with in the last 3 years I have developed venous insufficiency with reoccurring ulcers near my ankle bones both on the medial and lateral sides of the ankles.I have endured 2 ablations. The first in the left leg for the lesser saphenous vein and one on the right for the greater saphenous vein. I have visited OHSU(Oregon Health Sciences University) for more testing because I have 3 ulcers on my ankles, one on the left and two on the right(one on each side of the ankle medial and lateral. The vein docs up at OHSU say that I have 3 veins that the valves are not working properly and will require surgery. I weaned myself off of this medicine this last winter (2013)when I discovered that it was the cause of this condition. I do not have any family history of this condition, and I have always been very healthy and active despite my chronic lower back pain. My neurologist put me on this medication to help with the nerve pain when he discovered that I had scar tissue around the nerve root sleeves where they exit the S1. I am not sure if my veins will recover from being on this medication or if the damage is permanent and will reoccur, I have had to pay for the procedures after insurance paid, but now my new Obama plan does not want to pay for my surgery that I need for the 3 veins. These ulcers are the most painful wound I have ever dealt with, and they have a tendency to become infected with staph. I wish there was a class action I could be a part of to get my medical paid for, but most of all I wish I had never taken this drug, it has caused me more harm than good.

More reviews for: Gabapentin, Vitamin B12

Comments from related studies:

  • From this study (5 months ago):

  • I've been diagnosed with sero-negative rheumatoid arthritis. I have only tested minimally positive on the anti-CCP test and had a slightly high SED rate. My most recent tests showed some slight elevation in some RA marker tests, but nothing really significant. My rheumatologist is now doubting whether I have RA or some other pain syndrome going on.

    Reply

    IHateRA on Jul, 22, 2014:

    My first RA Dr. put me on Plaquenil, it seemed to work for six months, then stopped - I thought the dose would be adjusted but it wasn't, so I went to another RA Doc - C-RP wasn't too high, sero neg. Was put on methotrexate - I ended up with a mouth sore the NEXT day, then bumps started appearing on my face, like zits, but NOT zits. I didn't touch them, but they ulcerated, left me full of scars on face, legs, etc - I have been OFF methotrexate for 5 years AND still have the same problem along with a daily fever (100+) and severe sweating - I knew the bumps were a sign of being allergic to Methotrexate, I quit it right away, called Dr. to get in - they told me 3 months (I was an established patient). In terms of fever and sweating, the ONLY thing I have in common with some of these posts and drug lists is METHOTREXATE - I wouldn't allow a pet to take it. I seem to have more in common with a friend who as MS - but my reg. doc doesn't listen to that. I can't take bio. drugs (live in "fungal" region), so I take pain medicine - as little as possible, I guess the Methotrexate is STILL messing with my body. I have a very good acupuncturist - when I told him that my Doc. wasn't "sure" about RA, he poked me (lightly) with his finger in two places and ask which hurt more. He confirmed the RA as it travels on certain meridians in Chinese medicine. Had I picked a different spot for hurting more, then we would have to figure out what I really had. My joints are deteriorating but now I'm afraid of the drugs for RA, so I just put up with and manage the pain (which is extreme) with pain meds, cold therapy (I love my cryo-cuff), and acupuncture. I wish that the side effects of RA drugs weren't as bad as they are! Leaving Cymbalta, Lyrica, Plaquenil and Methotrexate (all at different times) OUT of my body made me realize that they did affect me - I was "foggy" and sluggish mentally but didn't really notice it until I quit them.

    Reply

  • From this study (7 months ago):

  • Have had unidentified autoimmune disease for five years, elevated cardiac enzymes from coronary vasospasms, joint pain, arthritis, muscle weakness, muscle tears

    Reply

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Complete drug side effects:

On eHealthMe, Gabapentin (gabapentin) is often used to treat neuralgia. Vitamin B12 (cobalamin) is often used to treat vitamin b12 deficiency. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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