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Review: taking Gabapentin and Wellbutrin together

Summary: drug interactions are reported among people who take Gabapentin and Wellbutrin together. This review analyzes the effectiveness and drug interactions between Gabapentin and Wellbutrin. It is created by eHealthMe based on reports of 4,268 people who take the same drugs from FDA and social media, and is updated regularly.

Personalized health information: on eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA and social media since 1977. Our tools are free and anonymous. 66 million people have used us. 200+ peer-reviewed medical journals have referenced our original studies. Start now >>>


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What are the drugs

Gabapentin has active ingredients of gabapentin. It is often used in pain. (latest outcomes from 39,682 Gabapentin users)

Wellbutrin has active ingredients of bupropion hydrochloride. It is often used in depression. (latest outcomes from 55,119 Wellbutrin users)

On May, 2, 2015: 4,268 people who take Gabapentin, Wellbutrin are studied

Gabapentin, Wellbutrin outcomes

Drug combinations in study:
- Gabapentin (gabapentin)
- Wellbutrin (bupropion hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Gabapentin is effective21.74%
(5 of 23 people)
(14 of 57 people)
(13 of 34 people)
(11 of 46 people)
(21 of 64 people)
(18 of 42 people)
(8 of 14 people)
(0 of 1 people)
Wellbutrin is effective5.56%
(1 of 18 people)
(17 of 49 people)
(9 of 23 people)
(13 of 47 people)
(28 of 72 people)
(22 of 41 people)
(15 of 28 people)
(0 of 1 people)

Drug effectiveness by gender :

Gabapentin is effective34.47%
(71 of 206 people)
(18 of 73 people)
Wellbutrin is effective40.00%
(82 of 205 people)
(22 of 73 people)

Drug effectiveness by age :

Gabapentin is effectiven/an/an/a28.00%
(14 of 50 people)
(24 of 102 people)
(19 of 153 people)
(26 of 129 people)
(7 of 113 people)
Wellbutrin is effectiven/an/an/a31.58%
(18 of 57 people)
(19 of 99 people)
(24 of 148 people)
(28 of 140 people)
(15 of 116 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
InsomniaSuicidal IdeationDyspnoeaPainAnxietyAnxietyOsteoporosis Post-menopausalPain
SomnolenceAnxietySuicide AttemptAnxietyDepressionPainFatigueAnxiety
Drug IneffectiveSuicide AttemptDrug IneffectiveCompleted SuicideRoad Traffic AccidentDepressionMuscle CrampsDepression
NauseaDepressionInfluenza Like IllnessDizzinessSuicide AttemptCoronary Artery DiseaseBurning Feet SyndromeNausea
FatigueDrug IneffectiveHiatus HerniaDrug IneffectiveSuicidal IdeationSuicidal IdeationAbdominal Pain LowerFatigue
Weight IncreasedMemory ImpairmentGastrooesophageal Reflux DiseaseHerniaPainConstipationPainDyspnoea
DysarthriaInsomniaTachycardiaNeuropathy PeripheralInsomniaWeight GainOedemaHeadache
Feeling AbnormalHallucinationVertigoDyspnoeaConvulsionDry MouthLoss Of Sensation, Numbness And Tingling, Paresthesias, Sensory Loss, Tingling And NumbnessBack Pain
HeadacheAngerHyperlipidaemiaType 2 Diabetes MellitusAngerType 2 Diabetes MellitusLoss Of LibidoWeight Increased
Back PainConvulsionDepressionOedema PeripheralTardive DyskinesiaHypertensionAppetite IncreasedDrug Ineffective

Most common drug interactions by gender * :

Weight IncreasedNausea
Drug IneffectiveFatigue
DyspnoeaBack Pain

Most common drug interactions by age * :

Diabetes Mellitusn/aCompleted SuicideCompleted SuicideAnxietyPainPainPain
Suicidal IdeationAggressionDepressionDepressionDepressionAnxietyFall
Weight IncreasedSuicide AttemptDrug IneffectiveSuicidal IdeationNauseaFatigueNausea
Maternal Drugs Affecting FoetusSuicidal IdeationAnxietyWeight IncreasedAnxietyDepressionAnxiety
Cleft LipGrand Mal ConvulsionPainHeadacheDiabetes MellitusNauseaDrug Ineffective
PollakiuriaConvulsionSuicide AttemptDyspnoeaDyspnoeaBack PainFatigue
InjuryHallucination, AuditoryNeuropathy PeripheralPainFatigueDyspnoeaDepression
AnxietySelf MutilationDiarrhoeaFatigueType 2 Diabetes MellitusDizzinessAsthenia
AnhedoniaPoor Quality SleepConstipationBack PainDrug IneffectiveArthralgiaDyspnoea
FearConvulsions NosTremorParaesthesiaHeadacheWeight IncreasedInsomnia

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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Do you take Gabapentin and Wellbutrin?


You are not alone! Join a related support group:
- support group for people who take Gabapentin
- support group for people who take Wellbutrin

Recent conversations of related support groups:

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More reviews for: Gabapentin, Wellbutrin

Comments from related studies:

  • From this study (3 weeks ago):

  • is topamax causing my bed wetting? it didn't when when i had been on it over a year and a half ago


  • From this study (1 month ago):

  • short term memory loss over past year gradually getting worse


  • From this study (2 months ago):

  • I get this when sitting or laying down. When I move to my side or get up I feel tingly then it goes away. I think its compression of a nerve or nerves.


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Complete drug side effects:

On eHealthMe, Gabapentin (gabapentin) is often used to treat neuralgia. Wellbutrin (bupropion hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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