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Review: Gravol and Zopiclone

This review analyzes the effectiveness and drug interactions between Gravol and Zopiclone. It is created by eHealthMe based on 42 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

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On Mar, 30, 2014: 42 people who reported to have interactions when taking Gravol, Zopiclone are studied

Trend of Gravol, Zopiclone's drug interactions, side effects and effectiveness reports (4437830)

Drug combinations in study:
- Gravol (dimenhydrinate)
- Zopiclone (eszopiclone)

eHealthMe real world results:

Most common interactions experienced by people in the use of Gravol, Zopiclone:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Asthenia (weakness)16
Ataxia (loss of full control of bodily movements)15
Mobility Decreased (ability to move is reduced)14
Malaise (a feeling of general discomfort or uneasiness)12
Swelling Face12
Nausea (feeling of having an urge to vomit)10
Osteoarthritis (a joint disease caused by cartilage loss in a joint)10
Cellulitis (infection under the skin)8
Ureteric Obstruction8

Most common interactions experienced by people in long term use of Gravol, Zopiclone:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Long-term Memory Loss3
Pain - Muscles (muscle pain)3
Hallucination, Auditory (perceiving sounds without auditory stimulus)2
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)2
Sense Of Oppression (sense of heavy burden)2
Tired Eyes (eyes feel achy, weak, or heavy due to intense use)2
Crackles Lung (noises that may be made by one or both lungs of a human with a respiratory disease during inhalation)2
Chest Pain2

How effective are the drugs:

not at allsomewhatmoderatehighvery high

Top conditions involved for these people * :

  1. Pain
  2. Insomnia
  3. Nausea
  4. Vitamin supplementation
  5. Blood pressure

Top co-used drugs for these people * :

  1. Acetaminophen
  2. Pantoprazole
  3. Lactulose
  4. Lorazepam
  5. Hydromorphone hcl

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Gravol, Zopiclone

You can also:

Complete drug side effects:

On eHealthMe, Gravol (dimenhydrinate) is often used to treat nausea. Zopiclone (eszopiclone) is often used to treat insomnia. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Comments from related studies:

  • From this study (1 year ago):

  • Drugs are not all taken on a daily basis oth than cymbalta, chronic migraine prevent, and trazodone and zopiclone at night. The rest are on an as needed basis. Like morphine only as last resort for migraine rescue, and robax only when back pain with out migraine, also nyquil only when needed during cold/flu sickness.


  • From this study (2 years ago):

  • To what extent do these meds interact to produce negative side effects? I am especially concerned about impact on present and future cognitive functioning/memory and mood problems


  • From this study (3 years ago):

  • Even taking this much medication to sleep sometimes I am still awake.This is very unpleasant.I feel like I am having an out of body experience.I do not know how to describe it clearly.


Can you answer these questions (what is this?):

More questions for: Gravol, Zopiclone

You may be interested at these reviews (what is this?):

  • Zopiclone causing sweating and memory loss
    Been on 10mg Zopivane for probably 5 - 10 years. In 2013 migrated to 15mg Zopiclone. Previously experienced hot flashes 3 times a week and in 2013 has increased to 3 to 5 times a night. Usually I have 3 hours sleep, then after midnight the flashed start. In the morning there are sopping wet clothe ...

  • Oxybutynin chloride and chest pain
    A urologist prescribed Vesicare (and Estrace cream) early in 2013 for urge incontinance. When hospitalized for cellulitis (never had it before) in May (2013), I took lots of I-V Clindamycin. The hospital had Ditropan on their formulary, and the urologist switched to it (it was cheaper)--and I con ...

More reviews for: Gravol, Zopiclone

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Related studies

- Gravol side effects
- Zopiclone side effects



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