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Review: taking Hydrea and Gleevec together

Summary: drug interactions are reported among people who take Hydrea and Gleevec together.

This review analyzes the effectiveness and drug interactions between Hydrea and Gleevec. It is created by eHealthMe based on reports of 595 people who take the same drugs from FDA and social media, and is updated regularly.





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What are the drugs

Hydrea has active ingredients of hydroxyurea. It is often used in polycythemia vera. (latest outcomes from 2,882 Hydrea users)

Gleevec has active ingredients of imatinib mesylate. It is often used in chronic myelogenous leukemia (cml). (latest outcomes from 20,443 Gleevec users)

On Mar, 6, 2015: 595 people who take Hydrea, Gleevec are studied

Hydrea, Gleevec outcomes

Drug combinations in study:
- Hydrea (hydroxyurea)
- Gleevec (imatinib mesylate)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Hydrea is effectiven/an/an/an/an/an/a100.00%
(1 of 1 people)
Gleevec is effectiven/an/a0.00%
(0 of 1 people)

Drug effectiveness by gender :

Hydrea is effective100.00%
(1 of 1 people)
Gleevec is effective0.00%
(0 of 1 people)

Drug effectiveness by age :

Hydrea is effectiven/an/an/an/an/an/an/a100.00%
(1 of 1 people)
Gleevec is effectiven/an/an/an/an/an/an/a0.00%
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
White Blood Cell Count DecreasedAnaemiaAnorexiaAnaemiaNeoplasm MalignantRenal Failure AcutePancytopeniaHaemoglobin Decreased
PyrexiaHaemoglobin DecreasedAngina PectorisRashBreast CancerSpinal OsteoarthritisPyrexia
AnaemiaFatigueMalignant Neoplasm ProgressionInterstitial Lung DiseaseDyspnoeaVomitingAnaemia
Platelet Count DecreasedDiarrhoeaConvulsionOxygen Saturation DecreasedAtrial FibrillationGastrointestinal HaemorrhageNeoplasm Malignant
ThrombocytopeniaWhite Blood Cell Count DecreasedLipase IncreasedGastric Antral Vascular EctasiaThrombocytopeniaPenis CarcinomaNausea
Interstitial Lung DiseaseHaematocrit DecreasedCoronary Artery OcclusionHaemoglobin DecreasedConstipationHaemorrhoidal HaemorrhageRash
Aspartate Aminotransferase IncreasedPlatelet Count DecreasedAscitesWhite Blood Cell Count DecreasedPruritusCardiac FailurePleural Effusion
Haemoglobin DecreasedOedema PeripheralHepatic IschaemiaRenal Failure ChronicAstheniaLeukocytosisWhite Blood Cell Count Increased
Blood Bilirubin IncreasedPancytopeniaHepatic Function AbnormalPleural EffusionFatigueBreast CancerWhite Blood Cell Count Decreased
DyspnoeaPlatelet Count IncreasedIschaemic HepatitisPericardial EffusionGene Mutation Identification Test PositiveNeoplasm MalignantChronic Myeloid Leukaemia

Most common drug interactions by gender * :

Haemoglobin DecreasedHaemoglobin Decreased
White Blood Cell Count DecreasedNeoplasm Malignant
NauseaInterstitial Lung Disease
FatiguePleural Effusion
DyspnoeaDrug Ineffective
RashWhite Blood Cell Count Increased
Platelet Count DecreasedChronic Myeloid Leukaemia

Most common drug interactions by age * :

Drug Exposure During PregnancyChloromaDrug Exposure During PregnancyPleural EffusionFace OedemaPyrexiaNeoplasm MalignantHaemoglobin Decreased
Premature BabyPleural EffusionPremature LabourWhite Blood Cell Count IncreasedRetinal OedemaAspartate Aminotransferase IncreasedRashAnaemia
Normal NewbornPathological FractureWhite Blood Cell Count IncreasedDrug Exposure During PregnancyMacular OedemaBlood Lactate Dehydrogenase IncreasedAnaemiaWhite Blood Cell Count Decreased
OsteolysisPlacental DisorderPancytopeniaGeneralised OedemaAlanine Aminotransferase IncreasedInterstitial Lung DiseasePyrexia
PneumoniaDyspnoeaSplenomegalyVomitingHeadachePyrexiaPlatelet Count Decreased
PancytopeniaHaemothoraxMaternal Exposure During PregnancyOedema NosVomitingPain In ExtremityNeoplasm Malignant
Renal Failure AcuteRespiratory DistressNormal NewbornDeathNeoplasm MalignantDrug IneffectivePleural Effusion
Haemoglobin DecreasedLeukostasisDyspnoea NosVentricular TachycardiaWhite Blood Cell Count DecreasedRenal Failure ChronicRash
Dermatitis AllergicInduced LabourChronic Myeloid LeukaemiaAnasarcaDyspnoeaFatigueOedema Peripheral
SwellingAcute Lymphocytic LeukaemiaGastric HaemorrhageDrug Exposure During PregnancyPlatelet Count DecreasedThrombocytopeniaFatigue

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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Do you take Hydrea and Gleevec?

You are not alone! Join a related mobile support group:
- support group for people who take Hydrea and Gleevec
- support group for people who take Gleevec
- support group for people who take Hydrea

Can you answer these questions (Ask a question):

More questions for: Gleevec, Hydrea

You may be interested at these reviews (Write a review):

  • Hydroxyurea and pomegranate juice
    sorry for my bad english.
    i am a retired physician, specialist in i.medicine & gastroenterology.
    have essencial thrombocythemia since year 2000.
    mild hypercholesterolemia once treated wiht symvastatin 20 mg/day.
    during a certain time i began to take 100 cc of pomegranate juice/3 times per week. before that my platelets were +/- stable at 400-450.000 y also my cholesterol at normal.
    after a few weeks of drinking pomegranate juice suddenly found: platelets fell to 300.000 and there was a leucopenia with absolute leucocytes count 1.7.
    also the cholesterol ldl and total fell to levels that never had before. at this stage stoped pomegranate juice and stoped hydrea and after more or les normalization began again hydrea when al the blood values return to a normal or higher level.
    I think that there is, probably, an interaction between hyderea and also smvastatin with pomegranate juice.
    for an unrelated cause i stoped symvastatin a few months ago. no i have a problem again with platelets that are high (480.000) and leucopenia (perhaps myelofibrosis ?). since a week we lowered de hydrea and i again began taking 100 cc of pomegranate juice twice a week. i have an appointment to my hematologist in 4 weeks and will do blood tests.
    that's all.
    alfredo leiser md, holon, israel

More reviews for: Gleevec, Hydrea

Complete drug side effects:

On eHealthMe, Hydrea (hydroxyurea) is often used to treat polycythemia vera. Gleevec (imatinib mesylate) is often used to treat chronic myelogenous leukemia (cml). Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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