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Review: taking Klonopin and Aldactone together

Summary: drug interactions are reported among people who take Klonopin and Aldactone together. This review analyzes the effectiveness and drug interactions between Klonopin and Aldactone. It is created by eHealthMe based on reports of 946 people who take the same drugs from FDA and social media, and is updated regularly.

Personalized health information: on eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA and social media since 1977. Our tools are free and anonymous. 66 million people have used us. 200+ peer-reviewed medical journals have referenced our original studies. Start now >>>


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What are the drugs

Klonopin has active ingredients of clonazepam. It is often used in stress and anxiety. (latest outcomes from 31,347 Klonopin users)

Aldactone has active ingredients of spironolactone. It is often used in acne. (latest outcomes from 20,203 Aldactone users)

On Apr, 25, 2015: 946 people who take Klonopin, Aldactone are studied

Klonopin, Aldactone outcomes

Drug combinations in study:
- Klonopin (clonazepam)
- Aldactone (spironolactone)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Klonopin is effective0.00%
(0 of 1 people)
(0 of 2 people)
(1 of 3 people)
(2 of 6 people)
(2 of 7 people)
(1 of 3 people)
(0 of 3 people)
Aldactone is effective0.00%
(0 of 1 people)
(1 of 2 people)
(3 of 4 people)
(1 of 5 people)
(3 of 5 people)
(2 of 4 people)
(1 of 2 people)

Drug effectiveness by gender :

Klonopin is effective28.57%
(6 of 21 people)
(0 of 4 people)
Aldactone is effective47.37%
(9 of 19 people)
(2 of 4 people)

Drug effectiveness by age :

Klonopin is effectiven/an/an/a14.29%
(1 of 7 people)
(1 of 5 people)
(1 of 22 people)
(1 of 13 people)
(2 of 6 people)
Aldactone is effectiven/an/an/a28.57%
(2 of 7 people)
(4 of 4 people)
(1 of 22 people)
(1 of 12 people)
(3 of 6 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
ThrombocytopeniaRenal Failure AcuteHepatic CirrhosisInjuryPainFallDry MouthAnxiety
Vascular PseudoaneurysmCardiac ArrestVarices OesophagealPainOsteomyelitisFace InjuryHair LossPain
DysgeusiaDyspnoeaPortal HypertensionMyocardial InfarctionArrhythmiaDepressionNauseaNausea
Inappropriate Antidiuretic Hormone SecretionFallAscitesStressInfectionMouth InjuryDry SkinCardiac Failure Congestive
HyponatraemiaHyperkalaemiaHypotension NosHypertoniaMalaiseOsteonecrosisFoetal Methotrexate SyndromeDyspnoea
PyrexiaMalaiseHaemoglobin DecreasedAnhedoniaEyelid PtosisSpinal Cord DisorderPenicilliosisDepression
Drug Rash With Eosinophilia And Systemic SymptomsBlood Pressure Systolic IncreasedDiarrhoea NosRenal FailureMacular DegenerationRoad Traffic AccidentExhaustion, Fatigue, Lethargy, Tiredness, WearinessOedema Peripheral
Acute Graft Versus Host DiseaseAbdominal Pain UpperDysentery NosFearCellulitisBack InjuryMuscle PainFall
Renal FailureBlood Calcium DecreasedHeadache NosMulti-organ FailureBlindness UnilateralOsteomyelitisStrabismusDizziness
Hepatitis CholestaticChest PainBlood Sodium DecreasedRenal ImpairmentCataractAnxietyAccommodation DisorderAsthenia

Most common drug interactions by gender * :

Cardiac Failure CongestiveFall
AnxietyAtrial Fibrillation
AstheniaOedema Peripheral
DizzinessCardiac Failure Congestive
Chest PainBack Pain

Most common drug interactions by age * :

HyponatraemiaInjuryn/aUrinary Tract InfectionMucosal InflammationDiabetes MellitusAnxietyPain
Renal FailureInfluenza Like IllnessRenal FailureBack PainNauseaCardiac Failure Congestive
DeathCardiac Failure CongestiveAnxietyPainCardiac Failure CongestiveAnxiety
Multi-organ FailureIntracardiac ThrombusVenoocclusive DiseaseNauseaDehydrationOedema Peripheral
Renal ImpairmentInsomniaInjuryOedemaHypotensionAtrial Fibrillation
Emotional DistressTuberculin Test PositiveAstheniaDiarrhoeaChest PainDyspnoea
StressPolycystic OvariesDyspnoeaDrug IneffectiveWeight IncreasedDepression

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Klonopin and Aldactone?


You are not alone! Join a related support group:
- support group for people who take Aldactone
- support group for people who take Klonopin

Recent conversations of related support groups:

Can you answer these questions (Ask a question):

More questions for: Aldactone, Klonopin

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More reviews for: Aldactone, Klonopin

Comments from related studies:

  • From this study (2 years ago):

  • Methatrexate closed air ways after taking it in pill form for 5+ years, then by injection for 1+ years, then went back on pill form. No reactions until return to pill form. swelling of tongue and wheezing. ER intervention.
    Codeine - severe nausea
    Sulfa and Penicillin - severe hives covering all upper body front and back.


  • From this study (2 years ago):

  • Leg cramps


  • From this study (3 years ago):

  • Just checking to see if there are bad interactions


Post a new comment    OR    Read more comments

Complete drug side effects:

On eHealthMe, Klonopin (clonazepam) is often used to treat stress and anxiety. Aldactone (spironolactone) is often used to treat acne. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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