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Review: Klonopin and Dexedrine

This review analyzes the effectiveness and drug interactions between Klonopin and Dexedrine. It is created by eHealthMe based on 117 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

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On Apr, 1, 2014: 117 people who reported to have interactions when taking Klonopin, Dexedrine are studied

Trend of Klonopin, Dexedrine's drug interactions, side effects and effectiveness reports (4969635)

Drug combinations in study:
- Klonopin (clonazepam)
- Dexedrine (dextroamphetamine sulfate)

eHealthMe real world results:

Most common interactions experienced by people in the use of Klonopin, Dexedrine:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Nausea (feeling of having an urge to vomit)68
Dyspnoea (difficult or laboured respiration)56
Somnolence (a state of near-sleep, a strong desire for sleep)47
Fatigue (feeling of tiredness)44
Hypoaesthesia (reduced sense of touch or sensation)32
Headache (pain in head)32
Insomnia (sleeplessness)30

Most common interactions experienced by people in long term use of Klonopin, Dexedrine:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Deep Vein Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)9
Nausea (feeling of having an urge to vomit)8
Fatigue (feeling of tiredness)7
Dyspnoea (difficult or laboured respiration)7
Palpitations (feelings or sensations that your heart is pounding or racing)6
Pulmonary Embolism (blockage of the main artery of the lung)6
Hypoaesthesia (reduced sense of touch or sensation)4
Oedema Peripheral (superficial swelling)4
Pain In Extremity4

How effective are the drugs:

not at allsomewhatmoderatehighvery high

Top conditions involved for these people * :

  1. Depression
  2. Pain
  3. Narcolepsy
  4. Anxiety
  5. Attention deficit/hyperactivity disorder

Top co-used drugs for these people * :

  1. Seroquel
  2. Heparin sodium injection
  3. Provigil
  4. Risperdal
  5. Neurontin

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Dexedrine, Klonopin

You can also:

Complete drug side effects:

On eHealthMe, Klonopin (clonazepam) is often used to treat stress and anxiety. Dexedrine (dextroamphetamine sulfate) is often used to treat attention deficit hyperactivity disorder. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Comments from related studies:

  • From this study (7 months ago):

  • Possible urethritis, but was wondering if dexedrine/clonazepam mixture could lead to foul smelling urine.


  • From this study (2 years ago):

  • I am curious to find out if "brain zaps" have been described as a "real life" side effect from Viibryd.


  • From this study (4 years ago):

  • I have personally found this a most helpful pain control medicine combined with the immediate release morphine to supplement has proven more beneficial than methadone, which I found extremely sedating and constipating. Also, the methadone did wear out its effect after 6 months where it no longer worked hardly at all. This is quite contradictory to what can be read on the internet and its being so highly regarded. I'm glad that chapter is closed!


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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Related studies

- Dexedrine side effects
- Klonopin side effects



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