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Review: taking Klonopin and Effexor Xr together

Summary: drug interactions are reported among people who take Klonopin and Effexor Xr together.

This review analyzes the effectiveness and drug interactions between Klonopin and Effexor Xr. It is created by eHealthMe based on reports of 5,167 people who take the same drugs from FDA and social media, and is updated regularly.

 

 

 

 

You are not alone: join a mobile support group for people who take Klonopin and Effexor Xr >>>

What are the drugs

Klonopin has active ingredients of clonazepam. It is often used in stress and anxiety. (latest outcomes from 31,296 Klonopin users)

Effexor xr has active ingredients of venlafaxine hydrochloride. It is often used in depression. (latest outcomes from 21,869 Effexor xr users)

On Jan, 7, 2015: 5,167 people who take Klonopin, Effexor Xr are studied

Klonopin, Effexor Xr outcomes

Drug combinations in study:
- Klonopin (clonazepam)
- Effexor Xr (venlafaxine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Klonopin is effective21.05%
(4 of 19 people)
50.00%
(17 of 34 people)
53.33%
(16 of 30 people)
40.48%
(17 of 42 people)
51.67%
(31 of 60 people)
50.00%
(23 of 46 people)
62.50%
(20 of 32 people)
50.00%
(1 of 2 people)
Effexor Xr is effective11.11%
(2 of 18 people)
27.27%
(9 of 33 people)
22.22%
(6 of 27 people)
22.86%
(8 of 35 people)
53.70%
(29 of 54 people)
33.87%
(21 of 62 people)
50.00%
(17 of 34 people)
0.00%
(0 of 2 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Drug Withdrawal SyndromeAnxietyDrug Withdrawal SyndromeDepressionDepressionAnxietyDrug IneffectiveDepression
Suicidal IdeationPainNauseaDrug IneffectiveSuicidal IdeationInsomniaDrug Withdrawal SyndromeNausea
NauseaSuicidal IdeationAnxietyPainType 2 Diabetes MellitusDepressionBack InjuryAnxiety
AnxietyNauseaHeadacheEmotional DistressSuicide AttemptPulmonary EmbolismAccident At WorkPain
HeadacheDrug Withdrawal SyndromeFatigueSuicidal IdeationAnxietyWeight IncreasedAnxietyHeadache
Drug IneffectiveSuicide AttemptDizzinessSuicide AttemptDrug Withdrawal SyndromeDrug Withdrawal SyndromeDry MouthDiabetes Mellitus
Completed SuicideWeight DecreasedVision BlurredAnxietyInsomniaDiabetes MellitusInsomniaFatigue
Suicide AttemptDepressionSuicidal IdeationHeadacheSepsisWithdrawal SyndromeType 2 Diabetes MellitusWeight Increased
Feeling AbnormalDrug IneffectiveAlopeciaCerebrovascular AccidentAbdominal PainFatigueMovement DisorderSuicidal Ideation
PainConvulsionInfluenza Like IllnessConstipationVomitingPainCognitive DisorderInsomnia

Drug effectiveness by gender :

FemaleMale
Klonopin is effective49.46%
(92 of 186 people)
46.84%
(37 of 79 people)
Effexor Xr is effective34.24%
(63 of 184 people)
36.25%
(29 of 80 people)

Most common drug interactions by gender * :

FemaleMale
DepressionDiabetes Mellitus
NauseaAnxiety
AnxietyDepression
PainPain
HeadacheType 2 Diabetes Mellitus
FatigueSuicidal Ideation
InsomniaWeight Increased
Weight IncreasedFatigue
Suicidal IdeationDrug Ineffective
DizzinessBack Pain

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Klonopin is effectiven/an/a50.00%
(4 of 8 people)
23.40%
(11 of 47 people)
34.83%
(31 of 89 people)
38.52%
(47 of 122 people)
24.00%
(24 of 100 people)
17.65%
(12 of 68 people)
Effexor Xr is effectiven/an/a20.00%
(2 of 10 people)
15.22%
(7 of 46 people)
20.00%
(18 of 90 people)
25.93%
(35 of 135 people)
15.31%
(15 of 98 people)
21.43%
(15 of 70 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Premature BabyPyrexiaSuicidal IdeationSuicide AttemptDiabetes MellitusNauseaDepressionPain
SwellingSerotonin SyndromeDepressionSuicidal IdeationNauseaDiabetes MellitusPainDepression
Weight IncreasedPhotophobiaWeight IncreasedNauseaDepressionHeadacheAnxietyFall
Ill-defined DisorderPalpitationsAngerAnxietyType 2 Diabetes MellitusPainInsomniaAnxiety
StomatitisHeadache NosAggressionDepressionAnxietyDepressionHeadacheNausea
AnorexiaNeck TightnessAgitationCompleted SuicideSuicidal IdeationType 2 Diabetes MellitusNauseaFatigue
Gastrointestinal MalformationSelf-injurious IdeationOverdoseWeight IncreasedAnxietyFatigueDrug Ineffective
Maternal Drugs Affecting FoetusPainType 2 Diabetes MellitusSuicide AttemptFatigueDizzinessDizziness
MeningoceleDiabetes MellitusDrug Withdrawal SyndromeDizzinessWeight IncreasedDiabetes MellitusHeadache
Drug Withdrawal Syndrome NeonatalPyrexiaFatigueHeadacheSuicidal IdeationType 2 Diabetes MellitusInsomnia

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Klonopin and Effexor Xr?

You are not alone! Join a related mobile support group:
- support group for people who take Klonopin and Effexor Xr
- support group for people who take Effexor Xr
- support group for people who take Klonopin

Recent conversations of related support groups:

  • Support group for people who take Effexor Xr
    Hi. just started 37.5 dose 3 days ago for anxiety. Sole care giver for 87 year old mom who jave been in hospital for 6 weeks waiting for a retirement home. Having chills and sweats. Also a bit dizzy. Was on Ciprolex before but got weak and severe head pain. Hoping these effexor symptoms will pass.

Can you answer these questions (Ask a question):

  • Can you stop trileptal cold turkey?
    I ran outta my Trileptal, the last time I took it was in the hospital on Saturday I was there for 2 days and I was normally taking 300mg 2x daily and the hospital gave me 600mg 4x on Saturday and the day before I took the one 300mg I had left in the morning. Since the hospital I have not had any Trileptal to be able to take because they didn't send me home with any because I'm from another State and I'm not sure if that's why but I should have my medicine tomorrow but I feel horrible and I just wanna know if physically I will be alright? Thank you so much and would appreciate a quick responce.
  • I tested positive for methadone, i have never taken this drug (1 answer)
    I tested positive for methadone, I have never taken this drug. My Dr said I had to have taken it because it was there and that a false positive is out of the question. Could my meds cause methadone to show up on a urine drug test
  • I take klonopin and diltiazem (calcium channel blocker blood pressure medicine) and am concerned about side effects. my accupuncturist recommends the ashwagandha. anyone have any issues with this?
    I take these prescription medications but have been going to an accupuncturist since 2012. I have trouble sleeping at night without my clonazepam and take naps during the day and am having trouble losing weight. She thinks that my adrenal glands may be fatigued and told me to try something called Adrenal Response which contains Sensoril Ashwagandha. When I looked up Ashwaganda it said that it could interact with the Clonazepam or Klonopin and also with High blood pressure medication. I am a little concerned. I mentioned this to her and she said they both are metabolized by the liver and it should be ok to take it, just to take it an hour or more after I take the Clonazepam. Has anyone had any issues with interactions with their prescribed meds while taking Ashwagandha? I don't want to have to monitor my blood pressure because my blood pressure medication works good for me. Any help would be appreciated because I want to try it but I am a little scared too. Thanks, Crystal
  • Does prozosin have interacction with efforr xr? (1 answer)
    Can Effexor Xr and Prazosin be taken together safely?
  • Can i take cialis and klonopin
    I've been taking klonopin and it's making it hard for me to have an erection. Can I take cialis while on klonopin?

More questions for: Effexor Xr, Klonopin

You may be interested at these reviews (Write a review):

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  • Effexor near death experience
    In 1999 I was prescribed 75mg time release Effexor. I took one pill and 4 hours later I became dizzy and it felt like a cold patch in the middle of my head. I ckecked my eyes as i started seeing too much light, my puples were dilated, all black. I managed to get up stairs and asked my mom to get me to hospital. I passed out, and as crazy as it sounds I had a vision of my nana. I knew I was gone.she told me to wake up. I wasn't breathing. I could hear my mom talking on the phone to 911saying I had no pulse. (She is an RN) the ambulance came and they couldn't find my blood pressure. I couldn't see very well. The ER doctors said to continue taking the meds and sent my home. I stopped taking the Effexor. I had the side effects for many months. I get aura migraines now and have extreme sensitivity to other drugs.
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  • A life of depression and fatigue (1 response)
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    do not smoke, avoid horrific or traumatic situations and try to find some enjoyment in life. If you have symptoms like mine seek early treatment put balance in your life. The often heard recommendations - get plenty of sleep, eat properly, learn to relax and avoid bad habits should not be ignored, they are critical to good physical and mental health.
  • 3 strong drugs together against neuropathic pain
    Neuropathic pain debuted when I was 24, now I'm 50. Received diagnosed with Ehler-Danlos syndrome (EDS), joint hypermobility type, when I was 35 years old. So it can take some time to get a diagnose. And as EDS-patient I do not belong to any clinic. Orthopedics says that EDS is not orthopedic, rheumatology says that EDS is not an autoimmune disease, GPs say that EDS is too difficult, and so on. Sooner or later we all end up at Psychiatry, even if we are not depressed.

    The first kind of pain I got when I was 24 came from low back, but I experienced as pelvic pain and leg pain. It was clearly a neuropathic pain, but it took years to find out. Later it was treated by a pain clinic with cortisone around the genitofemoral nerves (both sides). Since this treatment didn't result in lasting freedom from pain, the pain clinic started to give me RF (radio frequency) treatment. This made the pain disappeared after one year, and I was 80% free from it between 2002 and 2014, 12 years. The pain doctors said pain could return after 10 years.

    The other kind of neuropathic pain started 2003 with intense stomach pain. During 6 months I could hardly eat nothing due to nausea and vomiting. After this 6 months, stomach pain changed to almost unbearable pain in upper back.
    What happened 2003, and what all the doctors missed, was that the right lowest ribs slid up over the sternum. This rib dislocation is till there today, but now with a lot of cartilage formed around the rib where it is stuck in the lower end of the sternum. The dislocation is clearly visible on X-ray. This has greatly affected the thoracic spine. I have a scoliosis which I had not before 2003. And I still have severe pain in the thoracic spine.

    It was initially treated with morphine daily, and later with Durogesic (fentanyl), but this didn't help much. 2005 I was hospitalized because I had too much pain to take care of myself and my hygiene. After some months the doctors started to give me clonazepam because the muscles along the spine was in a chronic seizures. Clonazepam helped, but I could still have a lot of pain in two vertebrae in the thoracic spine. It felt as if someone drilled into the vertebrae without anesthesia. After a few months, doctors also prescribed me methadone. Then the pain disappeared almost completely. Since 2006, I have eaten clonazepam and methadone every day, and I need to sleep in an armchair to not get more pain because of moving during sleep.

    There are side effects. After 1,5 years with clonazepam and methadone I started to have panic attacks. Or rather one long panic attack which didn't stop before I got treatment with amitryptilin and pregabalin (Lyrica). These 2 medicines stopped the panic disorder completely after some hours, and the panic was then gone. Then I got side effects of these 2 medicines, amitryptilin & Lyrica, too. I gained a lot of weight (from 83 to 148 kg) and got much water (edema) in both my legs under the knees and in both feet. The feet could swallow to the double size. 2012 I stopped with amitryptilin and started to loose weight again (in Aug 2014 below 80 kg) and get less water in my legs. Today I eat as little medicines I can, but I have to take methadone, clonazepam and Lyrica every day, twice. If I try to take away one of these 3 medicines, I got pain problems at once. Lyrica is the most painful one to take away. In Sept-Dec 2013 I lowered Lyrica from 300 mg daily, to 150, then to 75 and finally 0 mg. The pain I had was extremely difficult to handle. It didn't help to take more methadone or anything else. I have checked on Internet and found that many people got pain from quitting with Lyrica. Most people start eating it again. So did I. But 2006 and 2007 it was enough to treat the pain with methadone and clonazepam, I got the Lyrica against anxiety not pain. But today I take Lyrica against pain.

    Beside weight gain and leg edema, clonazepam and Lyrica significantly affect the sexual desire. And Lyrica alone makes it almost impossible to ejaculate. All four drugs together (clonazepam, methadone, amitryptiline and Lyrica), make one forget all about sex life. You don't even miss it. When I stopped with amitryptiline and lowered Lyrica (still taking clonazepam and methadone), I could suddenly easily get erections again, feel desire, but not getting orgasms. This is quite difficult to deal with.

    The pain pattern is greatly affected, by pain and by the medicines. So is the mood. I get something which feels like heavy depression, especially if I take the medicines late that day. I should take a medicine like methadone 3 times a day, because the effects of the tablet lasts around 8 hours. But I take them every 12 hours, to have a low consumption in case doctors prescribe them too late (which happens, and then it's good to have a spouse going to the pharmacy buying them for you, because you have too much pain to go yourself).

    Since methadone is also used for treating heroine addicts, medical staff treat you with disrespect when they see that it says "methadone" in your health record. I need to show a certificate that says that I deal with chronic neuropathic pain, that I never have had problems with drug addiction, to get normal respect.

    I wanted to share this because I think I am alone in the world with these medicines in combination against neuropathic pain caused by hypermobile joints, joint dislocation and muscle spasms. After trying almost everything else, including surgery cutting nerves, methadone, clonazepam and Lyrica seems to be the only way to kill my pain. But it's a life where you always is questioned, because of the use of methadone. I can guarantee that everybody in the world should accept these medicines if they had experienced the unbearable pain I had in upper back before they started to give me clonazepam and methadone.

More reviews for: Effexor Xr, Klonopin

Comments from related studies:

  • From this study (3 months ago):

  • Within 3 to 4 months of starting ABILIFY, I gained about 40 pounds. As for the akathisia (feeling of restlessness or shaking on the inside), it wasn't bad until my dose got to 15mg. Eventually it went away and I still take 15mg/day. (haven't been able to lose much weight though. Side effects with EFFEXOR include severe sweating and a electric zap-like feeling in my head if I forget a dose or even miss it by a few hours.

    Reply

  • From this study (4 months ago):

  • My WBC count has been low for 4mos now. I'm lethargic, having problems sleeping & still experiencing a tremendous amount of pain (which I believe it has to do with the congenital lipoma on my brain stem-I've had excruciating pain as long as I can remember.)

    Reply

    really? on Sep, 22, 2014:

    I honestly thought this was a board where we could all learn from
    Each other's experiences. Unfortunately, everyone seems to be fixated on this one poster, asking a question for a "friend" & who is supposedly mixing all types of drugs. Let's get off of the 3rd party bashing because anyone on all of those drugs needs a lot more than people on a web page. Geez!!!!

    Reply

Post a new comment    OR    Read more comments

Complete drug side effects:

On eHealthMe, Klonopin (clonazepam) is often used to treat stress and anxiety. Effexor Xr (venlafaxine hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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