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Review: taking Klonopin and Percocet together

Summary: drug interactions are reported among people who take Klonopin and Percocet together.

This review analyzes the effectiveness and drug interactions between Klonopin and Percocet. It is created by eHealthMe based on reports of 2,377 people who take the same drugs from FDA and social media, and is updated regularly.


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On Apr, 2, 2015: 2,377 people who take Klonopin, Percocet are studied

Klonopin, Percocet outcomes

Drug combinations in study:
- Klonopin (clonazepam)
- Percocet (acetaminophen; oxycodone hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Klonopin is effective31.58%
(6 of 19 people)
(16 of 28 people)
(8 of 18 people)
(4 of 22 people)
(16 of 36 people)
(10 of 15 people)
(4 of 10 people)
Percocet is effective41.46%
(17 of 41 people)
(16 of 34 people)
(4 of 9 people)
(13 of 20 people)
(9 of 26 people)
(5 of 13 people)
(2 of 2 people)
(2 of 3 people)

Drug effectiveness by gender :

Klonopin is effective44.23%
(46 of 104 people)
(18 of 44 people)
Percocet is effective44.76%
(47 of 105 people)
(21 of 43 people)

Drug effectiveness by age :

Klonopin is effectiven/an/an/a24.14%
(14 of 58 people)
(16 of 90 people)
(15 of 42 people)
(13 of 49 people)
(6 of 26 people)
Percocet is effectiven/an/an/a31.58%
(18 of 57 people)
(19 of 108 people)
(12 of 51 people)
(14 of 49 people)
(5 of 25 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
PneumoniaDepressionMuscle PainDepressionAnxietyDepressionAsthmaPain
Ileus ParalyticPulmonary EmbolismDrowsinessDeep Vein ThrombosisDepressionAnxietyArthropathyNausea
Toxic EncephalopathyDeep Vein ThrombosisNauseaSuicidal IdeationPainSuicide AttemptAnxietyAnxiety
DehydrationIleusBack PainPathological GamblingSuicide AttemptIntentional OverdoseAnkle FractureDepression
ConstipationPathological GamblingConfusionHypersexualityIntentional OverdoseAggressionDepressionFall
AtelectasisSuicidal IdeationNeck PainObsessive-compulsive Personality DisorderDeep Vein ThrombosisDiabetes MellitusOral TorusBack Pain
Confusional StateNauseaAnxiety DisorderEmotional DistressAggressionConvulsionWeight IncreasedHeadache
DeliriumDrug Exposure During PregnancyMajor DepressionVentricular TachycardiaBipolar DisorderFatigueUrinary Tract DisorderDizziness
Small Intestinal ObstructionPremature LabourLoss Of Bladder ControlPleural EffusionMental Status ChangesMuscle WeaknessPneumoniaArthralgia
RhinorrhoeaCompulsive ShoppingDeep Vein ThrombosisCardiac Failure CongestiveCholecystitis ChronicAbnormal BehaviourOsteomyelitisDyspnoea

Most common drug interactions by gender * :

DepressionBack Pain
Back PainHeadache
DizzinessChest Pain
DyspnoeaDrug Ineffective

Most common drug interactions by age * :

AnorexiaOtitis MediaPainInsomniaNauseaPainPainPain
Ill-defined DisorderPainDeathNauseaPainDepressionAnxietyAnxiety
SwellingSkin InfectionCholecystitis ChronicUrinary Tract InfectionDepressionNauseaNauseaFall
Weight IncreasedPneumoniaGallbladder DisorderVomitingAnxietyBack PainDiarrhoeaDyspnoea
Diabetes MellitusDevice Related InfectionPancreatitisCholecystitis ChronicHeadacheAnxietyDepressionNausea
Type 2 Diabetes MellitusFeeding Tube ComplicationSphincter Of Oddi DysfunctionDyspnoeaDizzinessFallFallAsthenia
Neuroleptic Malignant SyndromeOverdoseAbdominal Pain UpperDrug Withdrawal SyndromeDizzinessHeadacheHeadache
Pulmonary EmbolismDrug AbuserCholelithiasisDrug IneffectiveConstipationBack PainPneumonia
Suicide AttemptLoss Of ConsciousnessBack PainDrug DependenceFatiguePain In ExtremityAnaemia
Systemic Lupus ErythematosusHeadacheAbdominal PainDyspnoeaArthralgiaWeight DecreasedBack Pain

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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- support group for people who take Klonopin
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Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Klonopin (clonazepam) is often used to treat stress and anxiety. Percocet (acetaminophen; oxycodone hydrochloride) is often used to treat pain. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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