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Review: taking Klonopin and Seroquel together

Summary: drug interactions are reported among people who take Klonopin and Seroquel together.

This review analyzes the effectiveness and drug interactions between Klonopin and Seroquel. It is created by eHealthMe based on reports of 7,732 people who take the same drugs from FDA and social media, and is updated regularly.

 

 

 

 

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What are the drugs

Klonopin has active ingredients of clonazepam. It is often used in stress and anxiety. (latest outcomes from 31,296 Klonopin users)

Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. (latest outcomes from 79,125 Seroquel users)

On Jan, 7, 2015: 7,732 people who take Klonopin, Seroquel are studied

Klonopin, Seroquel outcomes

Drug combinations in study:
- Klonopin (clonazepam)
- Seroquel (quetiapine fumarate)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Klonopin is effective25.00%
(5 of 20 people)
36.67%
(22 of 60 people)
45.71%
(16 of 35 people)
40.43%
(19 of 47 people)
55.74%
(34 of 61 people)
64.71%
(33 of 51 people)
50.00%
(18 of 36 people)
66.67%
(2 of 3 people)
Seroquel is effective26.83%
(11 of 41 people)
23.44%
(15 of 64 people)
34.38%
(11 of 32 people)
44.44%
(16 of 36 people)
55.22%
(37 of 67 people)
55.56%
(25 of 45 people)
53.33%
(8 of 15 people)
33.33%
(1 of 3 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
InsomniaType 2 Diabetes MellitusType 2 Diabetes MellitusType 2 Diabetes MellitusType 2 Diabetes MellitusType 2 Diabetes MellitusType 2 Diabetes MellitusDiabetes Mellitus
AnxietyDepressionDiabetes MellitusDiabetes MellitusDiabetes MellitusDiabetes MellitusInsomniaType 2 Diabetes Mellitus
SomnolenceInsomniaWeight IncreasedDiabetic NeuropathyBlood Cholesterol IncreasedBlood Cholesterol IncreasedFatigueWeight Increased
AgitationSuicidal IdeationHyperglycaemiaWeight IncreasedObesityObesitySuicidal IdeationInsomnia
Weight IncreasedDiabetes MellitusBlood Cholesterol IncreasedHyperlipidaemiaDiabetic NeuropathyHyperlipidaemiaDiabetes MellitusDepression
Type 2 Diabetes MellitusConvulsionInsomniaInsomniaWeight IncreasedDiabetic NeuropathyNeuropathy PeripheralAnxiety
Confusional StateAnxietyAbdominal Pain UpperDiabetes Mellitus Inadequate ControlHyperlipidaemiaNeuropathy PeripheralPancreatitisNausea
Suicidal IdeationSchizophreniaDiabetes Mellitus Inadequate ControlPancreatitisDiabetes Mellitus Inadequate ControlDiabetes Mellitus Inadequate ControlGastroenteritisSuicidal Ideation
Diabetes MellitusVomitingNeuropathy PeripheralBlood Cholesterol IncreasedNeuropathy PeripheralBack PainBack PainHeadache
ConvulsionAgitationDiabetic KetoacidosisNeuropathy PeripheralInsomniaBlood Triglycerides IncreasedAnxietyDrug Ineffective

Drug effectiveness by gender :

FemaleMale
Klonopin is effective49.28%
(103 of 209 people)
43.69%
(45 of 103 people)
Seroquel is effective45.05%
(91 of 202 people)
32.99%
(32 of 97 people)

Most common drug interactions by gender * :

FemaleMale
Diabetes MellitusDiabetes Mellitus
Type 2 Diabetes MellitusType 2 Diabetes Mellitus
InsomniaInsomnia
Weight IncreasedWeight Increased
DepressionDepression
AnxietySuicidal Ideation
NauseaAnxiety
HeadacheHyperglycaemia
Suicidal IdeationDrug Ineffective
DizzinessPancreatitis

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Klonopin is effectiven/an/a20.00%
(2 of 10 people)
29.91%
(32 of 107 people)
24.85%
(41 of 165 people)
31.15%
(38 of 122 people)
28.72%
(27 of 94 people)
28.57%
(8 of 28 people)
Seroquel is effectiven/an/a20.00%
(2 of 10 people)
28.16%
(29 of 103 people)
18.34%
(31 of 169 people)
26.89%
(32 of 119 people)
24.47%
(23 of 94 people)
25.00%
(7 of 28 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Diabetes MellitusTherapeutic Response Unexpected With Drug SubstitutionWeight IncreasedType 2 Diabetes MellitusType 2 Diabetes MellitusDiabetes MellitusDiabetes MellitusInsomnia
Weight IncreasedDrug IneffectiveSuicidal IdeationDiabetes MellitusDiabetes MellitusType 2 Diabetes MellitusType 2 Diabetes MellitusDepression
Type 2 Diabetes MellitusVision BlurredAggressionSuicidal IdeationDepressionWeight IncreasedInsomniaFatigue
PancreatitisDrug Effect DecreasedAgitationWeight IncreasedAnxietyInsomniaWeight IncreasedFall
Pulmonary HypertensionSuicide AttemptDepressionInsomniaWeight IncreasedPancreatitisDepressionDiabetes Mellitus
Drug Exposure During PregnancyComaAnxietyDyspnoeaHeadacheDepressionAnxietyConfusional State
Premature Rupture Of MembranesPupillary Reflex ImpairedType 2 Diabetes MellitusSuicide AttemptSuicidal IdeationDiabetic NeuropathyNauseaAnxiety
PregnancyParanoiaAbnormal BehaviourDizzinessDizzinessAnxietyPainNausea
GastritisDysarthriaSuicide AttemptHeadacheArthralgiaNeuropathy PeripheralNeuropathy PeripheralWeight Increased
Placenta PraeviaDroolingSomnolenceNauseaInsomniaBlood Cholesterol IncreasedSomnolencePneumonia

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Klonopin and Seroquel?

You are not alone! Join a related mobile support group:
- support group for people who take Klonopin and Seroquel
- support group for people who take Klonopin
- support group for people who take Seroquel

Can you answer these questions (Ask a question):

  • Can you stop trileptal cold turkey?
    I ran outta my Trileptal, the last time I took it was in the hospital on Saturday I was there for 2 days and I was normally taking 300mg 2x daily and the hospital gave me 600mg 4x on Saturday and the day before I took the one 300mg I had left in the morning. Since the hospital I have not had any Trileptal to be able to take because they didn't send me home with any because I'm from another State and I'm not sure if that's why but I should have my medicine tomorrow but I feel horrible and I just wanna know if physically I will be alright? Thank you so much and would appreciate a quick responce.
  • I tested positive for methadone, i have never taken this drug (1 answer)
    I tested positive for methadone, I have never taken this drug. My Dr said I had to have taken it because it was there and that a false positive is out of the question. Could my meds cause methadone to show up on a urine drug test
  • I take klonopin and diltiazem (calcium channel blocker blood pressure medicine) and am concerned about side effects. my accupuncturist recommends the ashwagandha. anyone have any issues with this?
    I take these prescription medications but have been going to an accupuncturist since 2012. I have trouble sleeping at night without my clonazepam and take naps during the day and am having trouble losing weight. She thinks that my adrenal glands may be fatigued and told me to try something called Adrenal Response which contains Sensoril Ashwagandha. When I looked up Ashwaganda it said that it could interact with the Clonazepam or Klonopin and also with High blood pressure medication. I am a little concerned. I mentioned this to her and she said they both are metabolized by the liver and it should be ok to take it, just to take it an hour or more after I take the Clonazepam. Has anyone had any issues with interactions with their prescribed meds while taking Ashwagandha? I don't want to have to monitor my blood pressure because my blood pressure medication works good for me. Any help would be appreciated because I want to try it but I am a little scared too. Thanks, Crystal
  • Can i take cialis and klonopin
    I've been taking klonopin and it's making it hard for me to have an erection. Can I take cialis while on klonopin?
  • I had bladder cancer and my doctor put me on metformin should i get off this
    I do not want to take this metformin if it may cause my bladder cancer to come badk

More questions for: Klonopin, Seroquel

You may be interested at these reviews (Write a review):

  • Terrible excessive sweating from hydrochlorothiazide
    I guess I fit the profile of who gets excessive sweating from HCTZ. I am a 65 year old female and suffered from excessive sweating for two years. With just very little exertion, I would pour sweat from the top of my head. It would run into my face and all over my hair. My hair would be ringing wet. I had heavy perspiration in the groin area and down my back also. I had to change clothing 2-3 times a day and wash up or shower that many times also. The doctor tried changing my Cymbalta and put me on Wellbutrin instead. It did absolutely no good. I went off the wellbutrin and back onto the Cymbalta. I did some research and saw that HCTZ could cause excessive sweating. Both my doctor and my pharmacist said that they had never heard of that. I went off the HCTZ, and my sweating stopped almost immediately. My doctor and my pharmacist were very surprised. I'm one of those people who frequently have different reactions to drugs than are typical. If you're having excessive perspiration and are on HCTZ, try going off of it. It just may be the culprit!
  • Panic after using flonase
    I was diagnosed with nasal polyps and put on Flonase (a steroid nose spray). It worked well to dry up post-nasal drip but I ended up with a bad case of panic and fear. I had overcome episodes of these nervous disorders but the Flonase brought it all back. I still suffer from panic even though I stopped the Flonase months ago. I had a bad attack on a bridge and also inside a grocery store. Personnel had to take me to the store office to calm me down. I am nearly agoraphobic now. I do go out alone but try to avoid after-dark. My life has been turned into daily dread of another attack. To think that I was more than ten years FREE of panic until I took the Flonase makes me feel so regretful that I ever took that stuff. It should be banned as there is enough evidence to do so from many people who now suffer debilitating and recurring panic.
  • A life of depression and fatigue (1 response)
    1) Family history of depression, 2) Diagnosed depression 1964-not treated until 1973, 3) Worked in medical field 35 years, 4) Emergency on-call 24/7, 5) Hospital 15 times major depression, 6) Tried nearly all MAOI, TCA, SSRI, SNRI, and ECT. 7) 100% Disability in 1998 for depression. Now at age 70 I have dysthymia, chronic fatigue, COPD, and PTSD. My recommendation to younger people - do not over stress,
    do not smoke, avoid horrific or traumatic situations and try to find some enjoyment in life. If you have symptoms like mine seek early treatment put balance in your life. The often heard recommendations - get plenty of sleep, eat properly, learn to relax and avoid bad habits should not be ignored, they are critical to good physical and mental health.
  • 3 strong drugs together against neuropathic pain
    Neuropathic pain debuted when I was 24, now I'm 50. Received diagnosed with Ehler-Danlos syndrome (EDS), joint hypermobility type, when I was 35 years old. So it can take some time to get a diagnose. And as EDS-patient I do not belong to any clinic. Orthopedics says that EDS is not orthopedic, rheumatology says that EDS is not an autoimmune disease, GPs say that EDS is too difficult, and so on. Sooner or later we all end up at Psychiatry, even if we are not depressed.

    The first kind of pain I got when I was 24 came from low back, but I experienced as pelvic pain and leg pain. It was clearly a neuropathic pain, but it took years to find out. Later it was treated by a pain clinic with cortisone around the genitofemoral nerves (both sides). Since this treatment didn't result in lasting freedom from pain, the pain clinic started to give me RF (radio frequency) treatment. This made the pain disappeared after one year, and I was 80% free from it between 2002 and 2014, 12 years. The pain doctors said pain could return after 10 years.

    The other kind of neuropathic pain started 2003 with intense stomach pain. During 6 months I could hardly eat nothing due to nausea and vomiting. After this 6 months, stomach pain changed to almost unbearable pain in upper back.
    What happened 2003, and what all the doctors missed, was that the right lowest ribs slid up over the sternum. This rib dislocation is till there today, but now with a lot of cartilage formed around the rib where it is stuck in the lower end of the sternum. The dislocation is clearly visible on X-ray. This has greatly affected the thoracic spine. I have a scoliosis which I had not before 2003. And I still have severe pain in the thoracic spine.

    It was initially treated with morphine daily, and later with Durogesic (fentanyl), but this didn't help much. 2005 I was hospitalized because I had too much pain to take care of myself and my hygiene. After some months the doctors started to give me clonazepam because the muscles along the spine was in a chronic seizures. Clonazepam helped, but I could still have a lot of pain in two vertebrae in the thoracic spine. It felt as if someone drilled into the vertebrae without anesthesia. After a few months, doctors also prescribed me methadone. Then the pain disappeared almost completely. Since 2006, I have eaten clonazepam and methadone every day, and I need to sleep in an armchair to not get more pain because of moving during sleep.

    There are side effects. After 1,5 years with clonazepam and methadone I started to have panic attacks. Or rather one long panic attack which didn't stop before I got treatment with amitryptilin and pregabalin (Lyrica). These 2 medicines stopped the panic disorder completely after some hours, and the panic was then gone. Then I got side effects of these 2 medicines, amitryptilin & Lyrica, too. I gained a lot of weight (from 83 to 148 kg) and got much water (edema) in both my legs under the knees and in both feet. The feet could swallow to the double size. 2012 I stopped with amitryptilin and started to loose weight again (in Aug 2014 below 80 kg) and get less water in my legs. Today I eat as little medicines I can, but I have to take methadone, clonazepam and Lyrica every day, twice. If I try to take away one of these 3 medicines, I got pain problems at once. Lyrica is the most painful one to take away. In Sept-Dec 2013 I lowered Lyrica from 300 mg daily, to 150, then to 75 and finally 0 mg. The pain I had was extremely difficult to handle. It didn't help to take more methadone or anything else. I have checked on Internet and found that many people got pain from quitting with Lyrica. Most people start eating it again. So did I. But 2006 and 2007 it was enough to treat the pain with methadone and clonazepam, I got the Lyrica against anxiety not pain. But today I take Lyrica against pain.

    Beside weight gain and leg edema, clonazepam and Lyrica significantly affect the sexual desire. And Lyrica alone makes it almost impossible to ejaculate. All four drugs together (clonazepam, methadone, amitryptiline and Lyrica), make one forget all about sex life. You don't even miss it. When I stopped with amitryptiline and lowered Lyrica (still taking clonazepam and methadone), I could suddenly easily get erections again, feel desire, but not getting orgasms. This is quite difficult to deal with.

    The pain pattern is greatly affected, by pain and by the medicines. So is the mood. I get something which feels like heavy depression, especially if I take the medicines late that day. I should take a medicine like methadone 3 times a day, because the effects of the tablet lasts around 8 hours. But I take them every 12 hours, to have a low consumption in case doctors prescribe them too late (which happens, and then it's good to have a spouse going to the pharmacy buying them for you, because you have too much pain to go yourself).

    Since methadone is also used for treating heroine addicts, medical staff treat you with disrespect when they see that it says "methadone" in your health record. I need to show a certificate that says that I deal with chronic neuropathic pain, that I never have had problems with drug addiction, to get normal respect.

    I wanted to share this because I think I am alone in the world with these medicines in combination against neuropathic pain caused by hypermobile joints, joint dislocation and muscle spasms. After trying almost everything else, including surgery cutting nerves, methadone, clonazepam and Lyrica seems to be the only way to kill my pain. But it's a life where you always is questioned, because of the use of methadone. I can guarantee that everybody in the world should accept these medicines if they had experienced the unbearable pain I had in upper back before they started to give me clonazepam and methadone.
  • Bipolar patient extremely violent on seraquel
    I have been diagnosed bipolar for over 10 years. 3 years ago I was taken off of topamax and my seraquel was upped to 300 mg from 100 because I was pregnant. I was very violent! Punching, breaking stuff, in jail, in the psych ward. Yes pregnancy and bipolar are not a perfect combination. I too thought it was the hormones. My husband and split several times over me punching him. We moved to a state cross country so there was no more family drama. Nothing worked! Over the last 3 years my life has been hell! I happen to run out of my seroquel (tg) it took 2 weeks to arrive. In that time my body went thru horrible withdrawals. I vowed I wouldn't take it any longer. I've been seraquel free for 2 months. I'm now on gabapentin and proud to say I have no anger issues! Not 1 punch has
    been thrown. I feel like a totally different person.

More reviews for: Klonopin, Seroquel

Comments from related studies:

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Post a new comment    OR    Read more comments

Complete drug side effects:

On eHealthMe, Klonopin (clonazepam) is often used to treat stress and anxiety. Seroquel (quetiapine fumarate) is often used to treat bipolar disorder. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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