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Review: Klonopin and Vyvanse

This review analyzes the effectiveness and drug interactions between Klonopin and Vyvanse. It is created by eHealthMe based on reports of 288 people who take the same drugs from FDA and social media, and is updated regularly.

Stay connected: join a mobile support group for people who take Klonopin and Vyvanse >>>

What are the drugs

Klonopin (what 31,209 Klonopin users reported?) has active ingredients of clonazepam. It is used in stress and anxiety.

Vyvanse (what 7,724 Vyvanse users reported?) has active ingredients of lisdexamfetamine dimesylate. It is used in attention deficit hyperactivity disorder.

On Aug, 13, 2014: 288 people who take Klonopin, Vyvanse are studied

Klonopin, Vyvanse outcomes

Drug combinations in study:
- Klonopin (clonazepam)
- Vyvanse (lisdexamfetamine dimesylate)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Klonopin is effective60.00%
(6 of 10 people)
(13 of 28 people)
(10 of 23 people)
(13 of 28 people)
(19 of 36 people)
(12 of 17 people)
(4 of 6 people)
(2 of 2 people)
Vyvanse is effective47.62%
(10 of 21 people)
(17 of 35 people)
(14 of 31 people)
(17 of 28 people)
(22 of 27 people)
(2 of 3 people)
(0 of 1 people)
(2 of 3 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Drug IneffectiveDizzinessFatigueInsomniaEuphoric MoodWeight GainNutrition - InadequateDrug Ineffective
TremorCondition AggravatedWeight GainAnxietyAnxietyAppetite - IncreasedItching - Burning EyesDepression
AnxietyNauseaExacerbation Of AnxietySerotonin SyndromeBone And Joint PainLoss Of LibidoMemory ImpairmentNausea
Abdominal PainDepressionPanic AttackDry MouthDepressionItchingAppetite - IncreasedAnxiety
Therapeutic Response UnexpectedSuicidal IdeationBlue VisionIrritabilityInsomnia ExacerbatedAnxiety AggravatedAnxiety AggravatedFatigue
HeadacheDisturbance In AttentionAgitated DepressionConstipationGerdConstipationMood SwingsVomiting
FatigueAnxietyBurning SensationRestlessnessFatigueSkin RashItchingPain
NauseaIrritabilityLoss Of Sensation, Numbness And Tingling, Paresthesias, Sensory Loss, Tingling And NumbnessPainItchingItching - Burning EyesSkin RashDrug Effect Decreased
DepressionMuscle CrampsMuscle Contractions InvoluntaryHeadachePain In ExtremityWeight Gain PoorNystagmusOverdose
InsomniaSerotonin SyndromeRestless Leg SyndromeNauseaSaliva AlteredEctopic HeartbeatDepressionIntentional Overdose

Drug effectiveness by gender :

Klonopin is effective55.10%
(54 of 98 people)
(25 of 52 people)
Vyvanse is effective54.08%
(53 of 98 people)
(31 of 51 people)

Most common drug interactions by gender * :

NauseaDrug Ineffective
DepressionIntentional Overdose
Drug IneffectiveFatigue
DizzinessDrug Effect Decreased
AstheniaSerotonin Syndrome

Drug effectiveness by age :

Klonopin is effectiven/an/a38.10%
(8 of 21 people)
(29 of 90 people)
(20 of 123 people)
(12 of 43 people)
(7 of 30 people)
(3 of 6 people)
Vyvanse is effectiven/an/a42.86%
(9 of 21 people)
(25 of 90 people)
(22 of 124 people)
(17 of 42 people)
(8 of 30 people)
(3 of 7 people)

Most common drug interactions by age * :

n/an/aConvulsionAggressionDizzinessDepressionDrug IneffectiveBalance Disorder
InsomniaNauseaNauseaIrritabilityFatigueWrist Fracture
HypoaesthesiaAbdominal Pain UpperPsoriatic ArthropathyAnxietyOverdoseAccident
IrritabilityInsomniaGastric BypassCondition AggravatedDepressionMusculoskeletal Disorder
Feeling AbnormalMalaiseSwellingVision BlurredNauseaUpper Limb Fracture
TicCompartment SyndromeWeight Loss PoorDrug Effect DecreasedPainLower Limb Fracture
FatigueRectal UlcerAsthmaNauseaAbdominal PainMultiple Fractures
AnorexiaTendonitisArthralgiaDry MouthAstheniaInfection
Chest DiscomfortPeroneal Nerve PalsySkin IrritationDisturbance In AttentionGait DisturbanceSpinal Fracture
Vision BlurredDehydrationIll-defined DisorderFatigueAnxietyLimb Crushing Injury

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Get connected! Join a mobile support group of people like you:
- group for people who take Klonopin and Vyvanse
- group for people who take Klonopin
- group for people who take Vyvanse

Comments from related studies:

  • From this study (3 weeks ago):

  • I'm tired, I have pain in the joints, I'm always nauseous, I'm always cold


  • From this study (2 months ago):

  • have been having severe back pain on lower spine right above tail bone


    Linda on Jun, 9, 2014:

    I reread your symptoms. It is primarily low back pain. It could be osteoarthritis, ankylosing spondylitis, possibly a slipped disc. I take back that it might be hemorrhoids as it sounds too far up. Definitely have it checked out.


    Linda on Jun, 9, 2014:

    Did you fall on coccyx ( tailbone ) ? I had similar symptoms and was diagnosed with Ankylosing Spondylitis, an autoimmune disease that affects the spine by coursing inflammation particularly in the sacral iliac joints which are located in your buttock. The pain can radiate to your back and mine sometimes goes to my hips, pelvis and sometimes down to my knee. I am a 52 year old female from their US. If you fell, you could have broken your coccyx, and that could take up to a year to feel better, ask your MD. Could be hemorrhoids, a polyp or mass and your rectum. You should definitely get it checked out.


  • From this study (7 months ago):

  • Do not take all drugs listed at same time. Am on "pulse therapy" with antimacrobials. Do not take coq10 when on Mepron/malarone. Take Florastor probiotic 2x's a day to fight c.diff & other probiotics. Also take FiberSmart, DigestSmart, & slippery elm, marshmallow root for GI regularity. Drink at least 4 cups green tea daily. CDC confirmed lyme positive in 2010 (September), was bit in May of same year. Had psychiatric & cognitive dysfunction immediately following rash. Further testing show active infection in brain - neuro-lyme dx'd.


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More reviews for: Klonopin, Vyvanse

Complete drug side effects:

On eHealthMe, Klonopin (clonazepam) is often used to treat stress and anxiety. Vyvanse (lisdexamfetamine dimesylate) is often used to treat attention deficit hyperactivity disorder. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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