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Review: Klonopin and Vyvanse

This review analyzes the effectiveness and drug interactions between Klonopin and Vyvanse. It is created by eHealthMe based on reports of 292 people who take the same drugs from FDA and social media, and is updated regularly.

Get connected: join a mobile support group for people who take Klonopin and Vyvanse >>>

What are the drugs

Klonopin (latest outcomes from 31,250 users) has active ingredients of clonazepam. It is often used in stress and anxiety.

Vyvanse (latest outcomes from 7,777 users) has active ingredients of lisdexamfetamine dimesylate. It is often used in attention deficit hyperactivity disorder.

On Oct, 26, 2014: 292 people who take Klonopin, Vyvanse are studied

Klonopin, Vyvanse outcomes

Drug combinations in study:
- Klonopin (clonazepam)
- Vyvanse (lisdexamfetamine dimesylate)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Klonopin is effective60.00%
(6 of 10 people)
(13 of 28 people)
(11 of 24 people)
(13 of 28 people)
(19 of 37 people)
(12 of 18 people)
(4 of 6 people)
(2 of 2 people)
Vyvanse is effective47.62%
(10 of 21 people)
(17 of 35 people)
(16 of 33 people)
(17 of 28 people)
(22 of 28 people)
(2 of 3 people)
(0 of 1 people)
(2 of 3 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Drug IneffectiveDizzinessWeight GainInsomniaDepressionWeight GainNutrition - InadequateDrug Ineffective
TremorCondition AggravatedFatigueAnxietyItchingAppetite - IncreasedItching - Burning EyesDepression
AnxietyNauseaRestless Legs SyndromeSerotonin SyndromeTremorLoss Of LibidoMemory ImpairmentNausea
Abdominal PainDepressionAnxiety AggravatedDry MouthBone And Joint PainItchingAppetite - IncreasedAnxiety
Therapeutic Response UnexpectedSuicidal IdeationNumbness And TinglingIrritabilityAnxietyAnxiety AggravatedAnxiety AggravatedFatigue
HeadacheDisturbance In AttentionPostnasal DripConstipationEuphoric MoodConstipationMood SwingsVomiting
FatigueAnxietyCsf Pressure IncreasedRestlessnessFatigueSkin RashItchingPain
NauseaIrritabilityExacerbation Of AnxietyPainGerdItching - Burning EyesSkin RashDrug Effect Decreased
DepressionMuscle CrampsAgitated DepressionHeadacheInsomnia ExacerbatedWeight Gain PoorNystagmusOverdose
InsomniaSerotonin SyndromePanic AttackNauseaPain In ExtremityEctopic HeartbeatDepressionIntentional Overdose

Drug effectiveness by gender :

Klonopin is effective55.00%
(55 of 100 people)
(25 of 53 people)
Vyvanse is effective55.00%
(55 of 100 people)
(31 of 52 people)

Most common drug interactions by gender * :

NauseaDrug Ineffective
DepressionIntentional Overdose
Drug IneffectiveDrug Effect Decreased
AstheniaSerotonin Syndrome

Drug effectiveness by age :

Klonopin is effectiven/an/a36.36%
(8 of 22 people)
(29 of 90 people)
(21 of 133 people)
(12 of 43 people)
(7 of 30 people)
(3 of 6 people)
Vyvanse is effectiven/an/a40.91%
(9 of 22 people)
(25 of 90 people)
(24 of 134 people)
(17 of 42 people)
(8 of 30 people)
(3 of 7 people)

Most common drug interactions by age * :

n/an/aConvulsionAggressionDizzinessDepressionDrug IneffectiveBalance Disorder
InsomniaNauseaNauseaIrritabilityFatigueWrist Fracture
HypoaesthesiaAbdominal Pain UpperOsteoarthritisAnxietyOverdoseAccident
IrritabilityInsomniaIll-defined DisorderCondition AggravatedDepressionMusculoskeletal Disorder
Feeling AbnormalMalaiseVomitingVision BlurredNauseaUpper Limb Fracture
TicCompartment SyndromeAsthmaDrug Effect DecreasedPainLower Limb Fracture
FatigueRectal UlcerGastric BypassNauseaAbdominal PainMultiple Fractures
AnorexiaTendonitisPsoriatic ArthropathyDry MouthAstheniaInfection
Chest DiscomfortPeroneal Nerve PalsySkin IrritationDisturbance In AttentionGait DisturbanceSpinal Fracture
Vision BlurredDehydrationSwellingFatigueAnxietyLimb Crushing Injury

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Klonopin and Vyvanse?

Get connected! Join a related mobile support group:
- support group for people who take Klonopin and Vyvanse
- support group for people who take Klonopin
- support group for people who take Vyvanse

Comments from related studies:

  • From this study (3 weeks ago):

  • I take the following doses of the above listed meds: vyvanse 70mg duloxetine 60mg klonopin 1mg 3xday as needed, levothyroxin 100mcg lamicatal 200 mg. My PCP suspects seratonin syndrome as I have all of the symptoms. Daily, I constantly get an electrical shock feeling in my brain when moving my eyes. Please help me.


  • From this study (1 month ago):

  • have been having severe back pain on lower spine right above tail bone


    novocaine on Sep, 26, 2014:

    Have you considered seeing a neurologist? Sometimes incontinence can be caused by nerve problems.


    Linda on Jun, 9, 2014:

    I reread your symptoms. It is primarily low back pain. It could be osteoarthritis, ankylosing spondylitis, possibly a slipped disc. I take back that it might be hemorrhoids as it sounds too far up. Definitely have it checked out.


    Linda on Jun, 9, 2014:

    Did you fall on coccyx ( tailbone ) ? I had similar symptoms and was diagnosed with Ankylosing Spondylitis, an autoimmune disease that affects the spine by coursing inflammation particularly in the sacral iliac joints which are located in your buttock. The pain can radiate to your back and mine sometimes goes to my hips, pelvis and sometimes down to my knee. I am a 52 year old female from their US. If you fell, you could have broken your coccyx, and that could take up to a year to feel better, ask your MD. Could be hemorrhoids, a polyp or mass and your rectum. You should definitely get it checked out.


  • From this study (2 months ago):



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Complete drug side effects:

On eHealthMe, Klonopin (clonazepam) is often used to treat stress and anxiety. Vyvanse (lisdexamfetamine dimesylate) is often used to treat attention deficit hyperactivity disorder. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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