Review: Klonopin and Wellbutrin
This review analyzes the effectiveness and drug interactions between Klonopin and Wellbutrin. It is created by eHealthMe based on reports of 5,495 people who take the same drugs from FDA and social media, and is updated regularly.
What are the drugs
Klonopin (latest outcomes from 31,234 users) has active ingredients of clonazepam. It is often used in stress and anxiety.
Wellbutrin (latest outcomes from 54,854 users) has active ingredients of bupropion hydrochloride. It is often used in depression.
On Sep, 13, 2014: 5,493 people who take Klonopin, Wellbutrin are studied
Drug combinations in study:
- Klonopin (clonazepam)
- Wellbutrin (bupropion hydrochloride)
Drug effectiveness over time :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years||not specified|
|Klonopin is effective||31.82%|
(14 of 44 people)
(40 of 86 people)
(28 of 58 people)
(35 of 69 people)
(60 of 116 people)
(45 of 69 people)
(49 of 66 people)
(4 of 7 people)
|Wellbutrin is effective||18.37%|
(9 of 49 people)
(16 of 82 people)
(21 of 66 people)
(23 of 64 people)
(34 of 104 people)
(44 of 83 people)
(24 of 49 people)
(1 of 4 people)
Most common drug interactions over time * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years||not specified|
|Anxiety||Depression||Nausea||Anxiety||Type 2 Diabetes Mellitus||Depression||Pain||Depression|
|Dizziness||Drug Exposure During Pregnancy||Type 2 Diabetes Mellitus||Nausea||Suicide Attempt||Anxiety||Insomnia||Anxiety|
|Drug Ineffective||Dilatation Ventricular||Back Pain||Type 2 Diabetes Mellitus||Diabetes Mellitus||Nausea||Dry Mouth||Nausea|
|Depression||Cardiomegaly||Headache||Headache||Weight Increased||Pain||Chest Pain||Drug Ineffective|
|Nausea||Ventricular Septal Defect||Abdominal Discomfort||Gastric Ulcer||Depression||Dizziness||Depression||Weight Increased|
|Insomnia||Congenital Anomaly||Abdominal Pain Upper||Depression||Fatigue||Suicide Attempt||Exhaustion, Fatigue, Lethargy, Tiredness, Weariness||Pain|
|Pain||Truncus Arteriosus Persistent||Gallbladder Injury||Emotional Distress||Pulmonary Embolism||Intentional Overdose||Pancreatitis||Diabetes Mellitus|
|Convulsion||Bundle Branch Block Right||Vomiting||Pain||Pain||Irritability||Panic Attack||Fatigue|
|Suicidal Ideation||Anxiety||Biliary Dyskinesia||Fatigue||Anxiety||Vision Blurred||Fatigue||Insomnia|
|Diarrhoea||Aortic Stenosis||Depression||Cardiac Arrest||Hysterectomy||Deep Vein Thrombosis||Anxiety||Dizziness|
Drug effectiveness by gender :
|Klonopin is effective||54.11%|
(191 of 353 people)
(84 of 162 people)
|Wellbutrin is effective||33.04%|
(113 of 342 people)
(59 of 159 people)
Most common drug interactions by gender * :
|Weight Increased||Type 2 Diabetes Mellitus|
Drug effectiveness by age :
|Klonopin is effective||100.00%|
(1 of 1 people)
(1 of 5 people)
(39 of 128 people)
(71 of 209 people)
(72 of 238 people)
(60 of 162 people)
(31 of 103 people)
|Wellbutrin is effective||0.00%|
(0 of 1 people)
(3 of 6 people)
(23 of 125 people)
(35 of 214 people)
(46 of 233 people)
(44 of 158 people)
(21 of 100 people)
Most common drug interactions by age * :
|Diabetes Mellitus||Speech Disorder||Nausea||Completed Suicide||Diabetes Mellitus||Depression||Depression||Drug Ineffective|
|Type 2 Diabetes Mellitus||Dysphagia||Vomiting||Suicidal Ideation||Type 2 Diabetes Mellitus||Anxiety||Fall||Dizziness|
|Pollakiuria||Drug Exposure During Pregnancy||Back Pain||Weight Increased||Depression||Diabetes Mellitus||Nausea||Fatigue|
|Major Depression||Maternal Drugs Affecting Foetus||Gallbladder Injury||Grand Mal Convulsion||Completed Suicide||Fatigue||Pain||Headache|
|Hyperglycaemia||Headache||Abdominal Discomfort||Suicide Attempt||Weight Increased||Dizziness||Headache||Asthenia|
|Injury||Weight Decreased||Biliary Dyskinesia||Drug Ineffective||Anxiety||Pain||Fatigue||Insomnia|
|Suicidal Ideation||Dizziness||Abdominal Pain Upper||Convulsion||Pain||Type 2 Diabetes Mellitus||Insomnia||Depression|
|Jaundice Nos||Lethargy||Diabetes Mellitus||Drug Ineffective||Weight Increased||Weight Increased||Weight Increased|
|Maternal Drugs Affecting Foetus||Electrocardiogram Qrs Complex Prolonged||Type 2 Diabetes Mellitus||Insomnia||Suicidal Ideation||Diabetes Mellitus||Anxiety|
* Some reports may have incomplete information.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
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Comments from related studies:
From this study (7 days ago):
From this study (1 month ago):
From this study (2 months ago):
Kevin Peters Ph.d on Mar, 4, 2013:
Sammy, I'm a white 45 male; just wanted to agree on that Klonopin remark. When I was 21 I had my second kidney transplant which was a BAD issue all together, at any rate the hospital did not include my medications taken at home after my surgery. I went thru the worst hallucinations and jerking and seizures you could ever possibly imagine. This went on for almost 3 1/2 weeks before we decided to have me taken OUT of the hospital and relocated before they ended up taking my life. Then the whole staff of paychology including the chief of psychiatry cane in my room to see what they could do, Finallu. During one of my few moments of clarity the C.O.F after blaming me if talking "drugs" prior to my transplant listened to my word of telling him the meds I was on before being admitted. After asking when was the last time I had received my Klonopin and me not knowing, he then reviewed the charts, and didn't see me receiving this med once. He stormed out of the room of about 9 docs and came back in with two Klonopin; for the first time in almost 4 weeks and after three surgeries the first 72 hours I was hospitalized, I was sleeping like a baby, for about 49 hours with NO MORE hallucinations, or seizures or jerking! I finally got out of there without a kidney since that kidney was supposed to go to another man named the same as I in a different city! I do take Xanax and probably always will. The half life on Klonopin is much different hence one if its dangers, Nevwr Ever stop this drug cold! I've been on dialysis 25 1/2 years now and suffered from intense skin cancers, but have fought and done all I can do to live a normal as possible life, working full time except when I'm in yet another surgery, over 32 general anesthetic procedures since 1987. I was the youngest boy-man to ever be on the USA soccer team ready to play in the Korea 1988 Olympics. What a change in life.....
All the Best,
chris on Jun, 4, 2011:
i have been taking clonzepam and trazedone and my speech is a very hoarse voice, I am wondering if if my speech problem is from these drugs's side effects.
TwoDimes on Apr, 15, 2012:
Upon occasion, I, too, have become hoarse and from the use of Klonopin. I was VERY hoarse when I tried to cold turkey off of 4mgs of Klonopin. I am now down to 1.5mgs per day and, still, (as I said, upon occasion, I become hoarse. I am sure that the use of Klonopin is the causative factor. - TwoDimes -
SammySushi on Jul, 10, 2012:
Omigosh, never cold turkey clonopin, esp that high of a dose. My dad had a major seizure and hallucinations doing so.
Christophe on Nov, 13, 2012:
I suffer from Hypothyroidism, High Cholesterol & Cancer survivor because of Zyprexa use and previously being prescribed Carbamezapine causing Thyroid damage. My best advice to you if you don't want Hypothyroidism is have regular blood tests, Thyroid damage can be undetected for up to 5 years with no symptoms found on regular blood tests prematurally. Make sure you buy iodised salt to use on food when eating this will help reduce your risk of getting Hypothyroidism. two signs of Hypothyriodism which the Carbamezapine & Zyprexa medication boxes labels wont tell you is if your face becomes puffed up, red or sun sensitive while taking these medications this is a sign of Hypothyroidism. It wont be found on your blood test but later on it could appear out of the blue. The other sign to look for is baldness or hair loss on your head, this is another symptom. I hope these comments will help you. You have to weight up the benefits and negatives taking medications if you decide to take these medicines or not. It depends on how you cope with the drug side effects.
AUDREY on Dec, 16, 2012:
STARTED TAKING DILTIAZEM 60 MG AND I AM VERY CONSTIPATED. 70 YEARS OLD, HEART SURGERY A FAST HEART RATE....
Sonya on Feb, 24, 2013:
You definately need to take a stool softener...straining during defication can cause major problems in people with cardiac problems.
Stillaguamish on Sep, 6, 2014:
My heart breaks for you and I'm so sorry you had to go through all that. I recently had two surgeries and was outraged at hospital treatment. I had to demand my regular meds and when they gave in, they only gave me 3 of 6
i started with 150mg Bupropion twice daily, but without my doctors word i started taking 300mg Bupropion daily after the first week. Felt like the drug was really helping, 3 days in with 300mg Bupropion twice daily i was fine 4th day today anxiety is gone but i felt like i was going to faint at work today.
The light head feeling came back when i started taking 300mg just like the first 3 days on 150mg
Fatigue has been getting worse since 2009. CKD stage 3 diagnosed July 2014.
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For two years I have been fighting with larangospasm. I have been hospitalized twice and treated with prednisone as well as nebulizers with albuterol. I had botox injections into my vocal cords last July 2013 and have a straw hanging around my neck for straw breathing. The last "attack" lasted one ...
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Complete drug side effects:
On eHealthMe, Klonopin (clonazepam) is often used to treat stress and anxiety. Wellbutrin (bupropion hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.
What is the drug used for and how effective is it:
- Klonopin is used in:
- Wellbutrin is used in:
Other drugs that are used to treat the same conditions:
- Klonopin alternatives:
- Wellbutrin alternatives:
NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).
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