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Review: Lamotrigine and Benadryl

This review analyzes the effectiveness and drug interactions between Lamotrigine and Benadryl. It is created by eHealthMe based on reports of 466 people who take the same drugs from FDA and social media, and is updated regularly.

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What are the drugs

Lamotrigine (what 15,744 Lamotrigine users reported?) has active ingredients of lamotrigine. It is used in bipolar disorder.

Benadryl (what 29,335 Benadryl users reported?) has active ingredients of diphenhydramine hydrochloride. It is used in allergies.

On Sep, 15, 2014: 466 people who take Lamotrigine, Benadryl are studied

Lamotrigine, Benadryl outcomes

Drug combinations in study:
- Lamotrigine (lamotrigine)
- Benadryl (diphenhydramine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Lamotrigine is effective16.67%
(1 of 6 people)
0.00%
(0 of 11 people)
0.00%
(0 of 3 people)
37.50%
(3 of 8 people)
53.85%
(7 of 13 people)
83.33%
(5 of 6 people)
50.00%
(1 of 2 people)
n/a
Benadryl is effective33.33%
(5 of 15 people)
37.50%
(3 of 8 people)
57.14%
(4 of 7 people)
18.18%
(2 of 11 people)
50.00%
(2 of 4 people)
0.00%
(0 of 1 people)
n/a0.00%
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
RashRashRashDizzinessCholesterosisHivesLower Blood PressureRash
Engraftment SyndromeUrticariaDepressionOxygen Saturation DecreasedWeight DecreasedSneezingNausea
Blood Bilirubin IncreasedAstheniaPruritusHeart Rate IrregularAbdominal PainRash PustularConvulsion
Renal Failure AcuteDepressionHallucination, VisualWeight GainNauseaDrowsinessPruritus
PyrexiaVision BlurredFeeling AbnormalNumbness And TinglingCholecystitis ChronicHeadachePain
InsomniaRhabdomyolysisPainHallucinationFaeces DiscolouredDizzinessTremor
Stevens-johnson SyndromePruritusDiarrhoeaHeadacheVomitingPetechiaeConfusional State
MalaiseExcessive Eye BlinkingBlisterCystitisAbdominal Pain UpperHeart Rate IrregularDepression
DizzinessBalance DisorderTardive DyskinesiaSneezingDiarrhoeaOxygen Saturation DecreasedHeadache
HeadacheTremorRash PustularHivesDeep Vein ThrombosisNumbness And TinglingVomiting

Drug effectiveness by gender :

FemaleMale
Lamotrigine is effective28.95%
(11 of 38 people)
54.55%
(6 of 11 people)
Benadryl is effective31.58%
(12 of 38 people)
44.44%
(4 of 9 people)

Most common drug interactions by gender * :

FemaleMale
RashCompleted Suicide
NauseaRash
PruritusWeight Increased
ConvulsionPneumonia
PainVomiting
HeadacheRenal Failure Acute
Confusional StateDyspepsia
TremorIncontinence
DepressionMania
PyrexiaGait Disturbance

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Lamotrigine is effectiven/an/a0.00%
(0 of 5 people)
4.00%
(1 of 25 people)
17.86%
(5 of 28 people)
27.78%
(5 of 18 people)
62.50%
(5 of 8 people)
33.33%
(1 of 3 people)
Benadryl is effectiven/an/a0.00%
(0 of 4 people)
4.17%
(1 of 24 people)
18.52%
(5 of 27 people)
33.33%
(6 of 18 people)
37.50%
(3 of 8 people)
33.33%
(1 of 3 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/aPetit Mal EpilepsySuicidal IdeationRashConvulsionRashRashSwelling
Weight IncreasedCompleted SuicideRashPruritusTremorDelirium
AkathisiaSuicidal IdeationVomitingHeadachePainPyrexia
ExcoriationAstheniaLoss Of ConsciousnessComaFallConfusional State
PyrexiaDepressionType 2 Diabetes MellitusMental DisorderMeningitis AsepticPain In Extremity
Vision BlurredNauseaHeadacheNauseaDepressionAnxiety
RashConvulsionDevice Related InfectionConfusional StateFatigueNeuropathy Peripheral
Gait DisturbanceFeeling AbnormalCompleted SuicideCompleted SuicideWeight DecreasedDry Mouth
Decreased AppetiteAbdominal PainDizzinessDizzinessWeight IncreasedDepression
Feeling GuiltyRenal Failure AcuteAnxietyTremorPyrexiaNeck Pain

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Lamotrigine and Benadryl?

Get connected! Join a mobile support group:
- group for people who take Lamotrigine and Benadryl
- group for people who take Benadryl
- group for people who take Lamotrigine

Comments from related studies:

  • From this study (2 months ago):

  • Itching in extremeties with no rash apparent. Eyes watery and burning. Twitching is in left eyelid. Itching started 8 days ago. Lotion does not help much. Diphenhydramine does not help much.

    Reply

  • From this study (2 years ago):

  • I a having swelling around my nipples (I'm not pregnant) and just recently increased my lamactal dosage by 1/2. Could this possibly be a side effect?

    Reply

Post a new comment    OR    Read more comments

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Complete drug side effects:

On eHealthMe, Lamotrigine (lamotrigine) is often used to treat bipolar disorder. Benadryl (diphenhydramine hydrochloride) is often used to treat allergies. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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