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Review: taking Lansoprazole and HCTZ together

Summary: drug interactions are reported among people who take Lansoprazole and HCTZ together.

This review analyzes the effectiveness and drug interactions between Lansoprazole and HCTZ. It is created by eHealthMe based on reports of 2,250 people who take the same drugs from FDA and social media, and is updated regularly.


You are not alone: join a support group for people who take Lansoprazole and HCTZ >>>

On Mar, 28, 2015: 2,250 people who take Lansoprazole, HCTZ are studied

Lansoprazole, HCTZ outcomes

Drug combinations in study:
- Lansoprazole (lansoprazole)
- HCTZ (hydrochlorothiazide)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Lansoprazole is effective50.00%
(1 of 2 people)
(1 of 4 people)
(2 of 5 people)
(8 of 10 people)
(5 of 6 people)
(8 of 8 people)
HCTZ is effective0.00%
(0 of 2 people)
(0 of 4 people)
(1 of 3 people)
(3 of 8 people)
(0 of 4 people)
(1 of 7 people)
(3 of 6 people)
(0 of 1 people)

Drug effectiveness by gender :

Lansoprazole is effective69.57%
(16 of 23 people)
(9 of 12 people)
HCTZ is effective25.00%
(6 of 24 people)
(2 of 11 people)

Drug effectiveness by age :

Lansoprazole is effectiven/an/an/an/a100.00%
(1 of 1 people)
(3 of 9 people)
(7 of 12 people)
(14 of 32 people)
HCTZ is effectiven/an/an/an/an/a25.00%
(2 of 8 people)
(3 of 13 people)
(3 of 37 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
HyponatraemiaConfusional StateIncreased Tendency To BruisePulmonary EmbolismDyspnoeaArthropathyPancreatitis NecrotisingNausea
DiarrhoeaBacterial SepsisGeneral Physical Health DeteriorationDeep Vein ThrombosisBlood Glucose IncreasedWeight Gain - UnintentionalNephrolithiasisPain
Oxygen Saturation DecreasedFallDry SkinFatiguePain In ExtremityEmotional DistressEscherichia InfectionDyspnoea
AstheniaBack PainBrittle NailsGeneral Physical Health DeteriorationInsomniaAbdominal CrampsEnterococcal InfectionChest Pain
PyrexiaMental Status ChangesConstipationDecreased AppetiteOedema PeripheralCoughPlatelet Count DecreasedAnaemia
Oedema PeripheralLacunar InfarctionPulmonary EmbolismAbdominal PainFatigueLightheadednessRenal FailureAnxiety
HeadacheMyocardial InfarctionPainArthralgiaChest PainDiarrhoeaWound InfectionFatigue
HypokalaemiaGeneral Physical Health DeteriorationEmotional DistressGastrointestinal Motility DisorderCellulitis StaphylococcalWeight IncreasedWhite Blood Cell Count IncreasedDiarrhoea
TachycardiaHeart Rate IrregularInjuryFailure To ThriveDeep Vein ThrombosisNauseaRespiratory FailureHypertension
FallPyrexiaAnxietyEscherichia InfectionNauseaResting TremorDisseminated Intravascular CoagulationGastrooesophageal Reflux Disease

Most common drug interactions by gender * :

Chest PainNausea
FatigueChest Pain
DiarrhoeaOsteonecrosis Of Jaw
Gastrooesophageal Reflux DiseaseDepression

Most common drug interactions by age * :

n/aRashHyperhidrosisGastrooesophageal Reflux DiseasePulmonary EmbolismNauseaNauseaNausea
PyrexiaHypertensionNauseaChest PainChest PainPainDyspnoea
Suicidal IdeationCholecystitis ChronicPainPainAnxietyAnaemia
Cold SweatDiabetes MellitusVomitingDyspnoeaAnaemiaFatigue
Blood Glucose AbnormalChest PainDeep Vein ThrombosisAnxietyDiarrhoeaDiarrhoea
RashUrinary Tract InfectionHypertensionDepressionVomitingPain
AgitationEating DisorderDepressionGastrooesophageal Reflux DiseasePyrexiaFall
HypotensionAbdominal PainDyspnoeaBack PainChest PainAnxiety
DiarrhoeaNauseaConstipationConstipationOedema Peripheral
Biliary ColicEmotional DistressFallWeight DecreasedAtrial Fibrillation

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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- support group for people who take HCTZ
- support group for people who take Lansoprazole

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Lansoprazole (lansoprazole) is often used to treat gastroesophageal reflux disease. Hctz (hydrochlorothiazide) is often used to treat high blood pressure. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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