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Review: taking Levothyroxine and Azithromycin together

Summary: drug interactions are reported among people who take Levothyroxine and Azithromycin together.

This review analyzes the effectiveness and drug interactions between Levothyroxine and Azithromycin. It is created by eHealthMe based on reports of 1,637 people who take the same drugs from FDA and social media, and is updated regularly.


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On Feb, 27, 2015: 1,636 people who take Levothyroxine Sodium, Azithromycin are studied

Levothyroxine Sodium, Azithromycin outcomes

Drug combinations in study:
- Levothyroxine Sodium (levothyroxine sodium)
- Azithromycin (azithromycin)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Levothyroxine Sodium is effective0.00%
(0 of 1 people)
(1 of 1 people)
(1 of 2 people)
(0 of 3 people)
(2 of 3 people)
(7 of 9 people)
(8 of 9 people)
Azithromycin is effective42.86%
(6 of 14 people)
(0 of 1 people)
(1 of 3 people)
(1 of 3 people)
(1 of 1 people)
(1 of 3 people)

Drug effectiveness by gender :

Levothyroxine Sodium is effective65.38%
(17 of 26 people)
(2 of 2 people)
Azithromycin is effective39.13%
(9 of 23 people)
(1 of 2 people)

Drug effectiveness by age :

Levothyroxine Sodium is effectiven/an/an/an/a14.29%
(1 of 7 people)
(7 of 11 people)
(9 of 23 people)
(2 of 2 people)
Azithromycin is effectiven/an/an/a100.00%
(1 of 1 people)
(1 of 7 people)
(2 of 9 people)
(5 of 21 people)
(1 of 2 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
NauseaDeep Vein ThrombosisCyanosisHeadachePulmonary EmbolismDeep Vein ThrombosisCompleted SuicidePain
FatiguePulmonary EmbolismAbdominal Pain UpperTinnitusDeep Vein ThrombosisAnxietyVomitingAnxiety
AstheniaHeadacheVomitingInsomniaDyspnoeaChest PainHypoglycaemic ComaNausea
Pulmonary EmbolismBiliary DyskinesiaDiarrhoeaSensation Of Foreign BodyAnxietyDyspnoeaPolyarthralgiaFatigue
DyspnoeaAnxietyAtrial Septal DefectPharyngolaryngeal PainDizzinessPulmonary EmbolismBreast TendernessDyspnoea
DehydrationDepression AggravatedDrug IneffectiveThroat IrritationCholecystitis ChronicDizzinessCoughInjury
MalaiseDeathCongenital Mitral Valve IncompetenceThroat TightnessDepressionDepressionPneumonia AspirationBack Pain
CoughTremorCholecystitis ChronicSwellingTransient Ischaemic AttackAttention Deficit/hyperactivity DisorderHypoxic-ischaemic EncephalopathyAsthenia
DysgeusiaNasal Septum PerforationWeight DecreasedTearfulnessDementiaVision BlurredCreatinine Renal Clearance DecreasedChest Pain
Drug HypersensitivityThoracic Vertebral FractureTooth InfectionApathySpeech DisorderAmnesiaNauseaDizziness

Most common drug interactions by gender * :

AnxietyChest Pain
Back PainBradycardia

Most common drug interactions by age * :

Patellofemoral Pain SyndromeComaAnxietyAnxietyDepressionPainPainFatigue
Stress FractureEar InfectionPainGallbladder DisorderFatigueNauseaAnxietyDyspnoea
Type 2 Diabetes MellitusViral InfectionEmotional DistressCholelithiasisInjuryAnxietyDyspnoeaAsthenia
OsteoarthritisBradycardiaCostochondritisCholecystitis ChronicAnxietyAnaemiaOedema PeripheralPain
ObesityLethargyAnhedoniaPainPulmonary EmbolismArthralgiaChest PainNausea
Blood Triglycerides IncreasedInsomnia NecPulmonary EmbolismInjuryPainHeadachePain In ExtremityAnxiety
HyperprolactinaemiaDiarrhoea NosDeep Vein ThrombosisDeep Vein ThrombosisPain In ExtremityVomitingFatigueDiarrhoea
LeiomyomaPersonality Disorder NosDeformityAbdominal Pain UpperBack PainBone DisorderNauseaDizziness
Blood Cholesterol IncreasedAnorexiaInjuryBiliary DyskinesiaAbdominal PainDepressionHypoaesthesiaCough
General Physical Health DeteriorationChest PainPulmonary EmbolismArthralgiaCholelithiasisNeck PainInjury

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Levothyroxine and Azithromycin?




You are not alone! Join a related mobile support group on :
- support group for people who take Azithromycin
- support group for people who take Levothyroxine Sodium

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Levothyroxine Sodium (levothyroxine sodium) is often used to treat hypothyroidism. Azithromycin (azithromycin) is often used to treat sinusitis. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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