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Review: taking Lexapro and Loratadine together

Summary: drug interactions are reported among people who take Lexapro and Loratadine together.

This review analyzes the effectiveness and drug interactions between Lexapro and Loratadine. It is created by eHealthMe based on reports of 871 people who take the same drugs from FDA and social media, and is updated regularly.





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What are the drugs

Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. (latest outcomes from 39,446 Lexapro users)

Loratadine has active ingredients of loratadine. It is often used in allergies. (latest outcomes from 10,980 Loratadine users)

On Jan, 19, 2015: 871 people who take Lexapro, Loratadine are studied

Lexapro, Loratadine outcomes

Drug combinations in study:
- Lexapro (escitalopram oxalate)
- Loratadine (loratadine)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Lexapro is effective0.00%
(0 of 4 people)
(2 of 7 people)
(0 of 6 people)
(8 of 10 people)
(3 of 8 people)
(1 of 2 people)
(2 of 2 people)
(1 of 2 people)
Loratadine is effective0.00%
(0 of 12 people)
(2 of 8 people)
(0 of 3 people)
(0 of 5 people)
(1 of 3 people)
(1 of 4 people)
(2 of 2 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
DepressionPainDyspnoeaObesityLoss Of ConsciousnessAnxietyDiabetes Mellitus AggravatedPain
NervousnessCytolytic HepatitisNauseaBlood Cholesterol IncreasedEmotional DistressDepressionDepressionNausea
PainCholestasisProcedural PainDiarrhoeaAnxietyAcute Respiratory FailureHigh Blood PressureDepression
Cholecystitis ChronicMental DisorderTherapeutic Response DecreasedHypothyroidismGeneralised Anxiety DisorderPain In ExtremityAcid RefluxAnxiety
Mental DisorderDiscomfortPulmonary EmbolismThyroid DisorderLacunar InfarctionPainDementia Due To Other General Medical ConditionFatigue
RestlessnessCholecystitis ChronicDrug Exposure During PregnancySuicide AttemptOesophageal SpasmGeneral Physical Health DeteriorationChronic PainAnaemia
Weight IncreasedGamma-glutamyltransferase IncreasedPulmonary CongestionUterine LeiomyomaPost Procedural ComplicationDyspnoeaOsteoarthritis AggravatedDyspnoea
DizzinessConfusional StateConfusional StateDiabetes MellitusPalpitationsPulmonary EmbolismDrowningHypertension
DiscomfortComplications Of Transplanted KidneyAnaemiaHyperlipidaemiaCerebrovascular AccidentDeep Vein ThrombosisHeadache
Impulsive BehaviourMicrolithiasisComplications Of Transplanted KidneyType 2 Diabetes MellitusBasal Cell CarcinomaChest PainDiarrhoea

Drug effectiveness by gender :

Lexapro is effective54.55%
(12 of 22 people)
(5 of 19 people)
Loratadine is effective21.05%
(4 of 19 people)
(2 of 18 people)

Most common drug interactions by gender * :

HypertensionWeight Decreased
Chest PainPneumonia
DiarrhoeaMuscular Weakness
InjuryWeight Increased
FatigueConfusional State

Drug effectiveness by age :

Lexapro is effectiven/an/an/a20.00%
(3 of 15 people)
(4 of 8 people)
(4 of 14 people)
(4 of 15 people)
(2 of 5 people)
Loratadine is effectiven/an/an/a14.29%
(2 of 14 people)
(1 of 8 people)
(1 of 11 people)
(1 of 15 people)
(1 of 5 people)

Most common drug interactions by age * :

Premature BabyPainDehydrationPainNauseaPainDepressionAnaemia
Immature Respiratory SystemWeight DecreasedDiarrhoeaAnxietyPainDepressionPainDiarrhoea
Drug Exposure During PregnancyLoss Of ConsciousnessSyncopeCholecystitis ChronicDyspnoeaHypertensionAnxietyConstipation
InsomniaVomitingCholelithiasisCholecystitis ChronicBack PainInjuryNausea
DyspnoeaThrombocytopeniaEmotional DistressDepressionAstheniaNauseaPain
Eating DisorderUrinary Tract InfectionVomitingWeight IncreasedHypokalaemiaAnaemiaCardiac Failure Congestive
HypersensitivityPyrexiaMental DisorderDiabetes MellitusType 2 Diabetes MellitusEmotional DistressDyspnoea
CoughPseudocystInjuryChest PainHeadacheFallUrinary Tract Infection
ColitisAgitationSuicidal IdeationMental Status ChangesFatigueVomiting
PancreatitisDiscomfortMental DisorderDysarthriaInsomniaHypotension

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Lexapro and Loratadine?

You are not alone! Join a related mobile support group:
- support group for people who take Lexapro and Loratadine
- support group for people who take Lexapro
- support group for people who take Loratadine

Can you answer these questions (Ask a question):

More questions for: Lexapro, Loratadine

You may be interested at these reviews (Write a review):

  • Tourette's syndrome caused by lexapro
    After two months on lexapro, Tourette's syndrome started and has continued for 18 months, increasing in intensity and frequency. After one month off the Lexapro, the Tourette's syndrome has stopped completely.
  • Escitalopram /narcolepsy
    Began taking escitalopram one month ago. Having narcoleptic type sleep incidents as well as unwanted suicidal thoughts. Legs and arms also go out. Sleeping up to thirteen or more hours per day.
  • Lexapro and memory loss
    I actually have no idea what other medicine I was on the week I took Lexapro, it was back at the end of February 2014 right before I checked myself into the psych hospital. I formed no memory for a whole week just because of one drug! My friends and family tell me what happened that week and I have called them a liar because there is no recall from that week! I have been on psychiatric drugs for over 14 years and have never had such a horrible reaction as I did with Lexapro! The side effects do not include this reaction, but I didn't sleep at all that week or so I am told and there is just nothing, not even a little memory. Take this as you will I am not saying everyone gets this side effect I am just saying it is not impossible. I learned a lesson I don't remember, but will never take Lexapro again! It was dangerous for me!
  • Patients having false positives while on remeron
    I have had a few patients complain they are failing drug tests for Amphetamines while on remeron, and have claimed to have not used any type of Amphetamine or any (Mixed Salts). These patients are all or were on probation, parole, or under some stipulation. Iv realized most of these patients are taking another psych med. The list consists of insomnia meds such as Ambien(zolpidem), Sonata(zaleplon),Lunesta(eszopiclone). Also the Anti-Depressants Lexapro (escitalopram)and Prozac (fluoxetine). One of my patients was on Diazepam (Valium). I have switched medicines, particularly the Ambien, Lexapro, and Prozac have reversed the false negative. I prescribe many of my patients remeron. I'm a big believer in its effects on my patients moods and everyday depression. I have heard this happening before, but this was the first time I have ever had this happen to one of my own patients.(These were 5 separate patients in the span of 16 months) Of course none of these patients were criminalized based on lab results, but the issue still lies there. I know this is common for a lot of script meds to give false positives for narcotics. This is just obviously one I am putting out there. Let me know if anyone has experienced something similar.
  • Yes, lexapro does cause tinnitus! (1 response)
    Whenever I forget to take my Lexapro in the morning, I get a high pitched ringing in my ears which starts around 1:00 pm, which won't go away until a few hours after I take the drug. Once I was out of the medication and I almost screamed because the ringing got so bad! I don't think it is as "rare" in the listed side effects as the manufacturer states.

More reviews for: Lexapro, Loratadine

Comments from related studies:

  • From this study (6 months ago):

  • foot pain after sitting for awhile and after sleeping.


  • From this study (6 months ago):

  • I stop taking my phone mine the first after I taking Lexapro and still severe chest pain I'm bloating like crazy also


  • From this study (9 months ago):

  • Diabetes Mellitus, insulin dependent for 53 years, brittle.
    Chronic pain due to needing bone graph in femur/hip joint due to femur fracture 5 years ago which surgery did not properly repair--chronic bone deterioration in that left femur, lumbar spinal stenosis-awaiting surgery to L4/L5 slipped/ruptured disc. Left femur 1 inch shorter now than right femur.Chronic deterioration in right shoulder socket and upper arm, and clavicle--all due to longevity of insulin dependence for majority of life. Osteoporosis does not show up in blood tests, only osteopenia, altho oddities in bone density tests. Insurance w/not approve Exelon patch-concerns about Aricept effects on body and mind. Educated, intelligent, fully functional and capable post-menopausal female, worried that Aricept will have unwanted side effects to functionality. Living on on in an apartment. Too functional for a nursing facility. Please tell me what you think. Thanks, Teresa Shumate,


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Complete drug side effects:

On eHealthMe, Lexapro (escitalopram oxalate) is often used to treat depression. Loratadine (loratadine) is often used to treat allergies. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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