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Review: Lexapro and Mirapex and Klonopin and Clonidine





Summary: drug interactions are reported among people who take Lexapro and Mirapex and Klonopin and Clonidine together.

This review analyzes the effectiveness and drug interactions between Lexapro and Mirapex and Klonopin and Clonidine. It is created by eHealthMe based on reports of 7 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Lexapro and Mirapex and Klonopin and Clonidine >>>

What are the drugs

Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. (latest outcomes from Lexapro 39,406 users)

Mirapex has active ingredients of pramipexole dihydrochloride. It is often used in restless leg syndrome. (latest outcomes from Mirapex 10,311 users)

Klonopin has active ingredients of clonazepam. It is often used in stress and anxiety. (latest outcomes from Klonopin 31,277 users)

Clonidine has active ingredients of clonidine. It is often used in high blood pressure. (latest outcomes from Clonidine 9,662 users)

On Nov, 26, 2014: 7 people who take Lexapro, Mirapex, Klonopin, Clonidine are studied

Lexapro, Mirapex, Klonopin, Clonidine outcomes

Drug combinations in study:
- Lexapro (escitalopram oxalate)
- Mirapex (pramipexole dihydrochloride)
- Klonopin (clonazepam)
- Clonidine (clonidine)

Drug effectiveness over time :

n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
n/an/an/an/an/an/an/aSpondylolisthesis
Therapeutic Agent Toxicity
Dehydration
Intervertebral Disc Protrusion
Hypotension
Vomiting
Nausea
Musculoskeletal Discomfort
Limb Injury
Dyspnoea

Drug effectiveness by gender :

n/a

Most common drug interactions by gender * :

FemaleMale
SpondylolisthesisElectrocardiogram Abnormal
Therapeutic Agent ToxicityWheezing
DehydrationLethargy
Intervertebral Disc ProtrusionChest Pain
HypotensionDyspnoea
Musculoskeletal Discomfort
Vomiting
Nausea
Limb Injury
Depressed Mood

Drug effectiveness by age :

n/a

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/an/an/an/an/an/aSpondylolisthesisTherapeutic Agent Toxicity
DehydrationVomiting
Musculoskeletal DiscomfortSpondylolisthesis
Therapeutic Agent ToxicityNausea
HypotensionHypotension
Intervertebral Disc ProtrusionIntervertebral Disc Protrusion
VomitingDehydration
Nausea
Limb Injury
Dyspnoea

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Lexapro and Mirapex and Klonopin and Clonidine?

You are not alone! Join a related mobile support group:
- support group for people who take Lexapro and Mirapex and Klonopin and Clonidine
- support group for people who take Clonidine
- support group for people who take Klonopin
- support group for people who take Lexapro
- support group for people who take Mirapex

Can you answer these questions (Ask a question):

More questions for: Clonidine, Klonopin, Lexapro, Mirapex

You may be interested at these reviews (Write a review):

  • Panic after using flonase
    I was diagnosed with nasal polyps and put on Flonase (a steroid nose spray). It worked well to dry up post-nasal drip but I ended up with a bad case of panic and fear. I had overcome episodes of these nervous disorders but the Flonase brought it all back. I still suffer from panic even though I stopped the Flonase months ago. I had a bad attack on a bridge and also inside a grocery store. Personnel had to take me to the store office to calm me down. I am nearly agoraphobic now. I do go out alone but try to avoid after-dark. My life has been turned into daily dread of another attack. To think that I was more than ten years FREE of panic until I took the Flonase makes me feel so regretful that I ever took that stuff. It should be banned as there is enough evidence to do so from many people who now suffer debilitating and recurring panic.
  • Escitalopram /narcolepsy
    Began taking escitalopram one month ago. Having narcoleptic type sleep incidents as well as unwanted suicidal thoughts. Legs and arms also go out. Sleeping up to thirteen or more hours per day.
  • A life of depression and fatigue
    1) Family history of depression, 2) Diagnosed depression 1964-not treated until 1973, 3) Worked in medical field 35 years, 4) Emergency on-call 24/7, 5) Hospital 15 times major depression, 6) Tried nearly all MAOI, TCA, SSRI, SNRI, and ECT. 7) 100% Disability in 1998 for depression. Now at age 70 I have dysthymia, chronic fatigue, COPD, and PTSD. My recommendation to younger people - do not over stress,
    do not smoke, avoid horrific or traumatic situations and try to find some enjoyment in life. If you have symptoms like mine seek early treatment put balance in your life. The often heard recommendations - get plenty of sleep, eat properly, learn to relax and avoid bad habits should not be ignored, they are critical to good physical and mental health.
  • 3 strong drugs together against neuropathic pain
    Neuropathic pain debuted when I was 24, now I'm 50. Received diagnosed with Ehler-Danlos syndrome (EDS), joint hypermobility type, when I was 35 years old. So it can take some time to get a diagnose. And as EDS-patient I do not belong to any clinic. Orthopedics says that EDS is not orthopedic, rheumatology says that EDS is not an autoimmune disease, GPs say that EDS is too difficult, and so on. Sooner or later we all end up at Psychiatry, even if we are not depressed.

    The first kind of pain I got when I was 24 came from low back, but I experienced as pelvic pain and leg pain. It was clearly a neuropathic pain, but it took years to find out. Later it was treated by a pain clinic with cortisone around the genitofemoral nerves (both sides). Since this treatment didn't result in lasting freedom from pain, the pain clinic started to give me RF (radio frequency) treatment. This made the pain disappeared after one year, and I was 80% free from it between 2002 and 2014, 12 years. The pain doctors said pain could return after 10 years.

    The other kind of neuropathic pain started 2003 with intense stomach pain. During 6 months I could hardly eat nothing due to nausea and vomiting. After this 6 months, stomach pain changed to almost unbearable pain in upper back.
    What happened 2003, and what all the doctors missed, was that the right lowest ribs slid up over the sternum. This rib dislocation is till there today, but now with a lot of cartilage formed around the rib where it is stuck in the lower end of the sternum. The dislocation is clearly visible on X-ray. This has greatly affected the thoracic spine. I have a scoliosis which I had not before 2003. And I still have severe pain in the thoracic spine.

    It was initially treated with morphine daily, and later with Durogesic (fentanyl), but this didn't help much. 2005 I was hospitalized because I had too much pain to take care of myself and my hygiene. After some months the doctors started to give me clonazepam because the muscles along the spine was in a chronic seizures. Clonazepam helped, but I could still have a lot of pain in two vertebrae in the thoracic spine. It felt as if someone drilled into the vertebrae without anesthesia. After a few months, doctors also prescribed me methadone. Then the pain disappeared almost completely. Since 2006, I have eaten clonazepam and methadone every day, and I need to sleep in an armchair to not get more pain because of moving during sleep.

    There are side effects. After 1,5 years with clonazepam and methadone I started to have panic attacks. Or rather one long panic attack which didn't stop before I got treatment with amitryptilin and pregabalin (Lyrica). These 2 medicines stopped the panic disorder completely after some hours, and the panic was then gone. Then I got side effects of these 2 medicines, amitryptilin & Lyrica, too. I gained a lot of weight (from 83 to 148 kg) and got much water (edema) in both my legs under the knees and in both feet. The feet could swallow to the double size. 2012 I stopped with amitryptilin and started to loose weight again (in Aug 2014 below 80 kg) and get less water in my legs. Today I eat as little medicines I can, but I have to take methadone, clonazepam and Lyrica every day, twice. If I try to take away one of these 3 medicines, I got pain problems at once. Lyrica is the most painful one to take away. In Sept-Dec 2013 I lowered Lyrica from 300 mg daily, to 150, then to 75 and finally 0 mg. The pain I had was extremely difficult to handle. It didn't help to take more methadone or anything else. I have checked on Internet and found that many people got pain from quitting with Lyrica. Most people start eating it again. So did I. But 2006 and 2007 it was enough to treat the pain with methadone and clonazepam, I got the Lyrica against anxiety not pain. But today I take Lyrica against pain.

    Beside weight gain and leg edema, clonazepam and Lyrica significantly affect the sexual desire. And Lyrica alone makes it almost impossible to ejaculate. All four drugs together (clonazepam, methadone, amitryptiline and Lyrica), make one forget all about sex life. You don't even miss it. When I stopped with amitryptiline and lowered Lyrica (still taking clonazepam and methadone), I could suddenly easily get erections again, feel desire, but not getting orgasms. This is quite difficult to deal with.

    The pain pattern is greatly affected, by pain and by the medicines. So is the mood. I get something which feels like heavy depression, especially if I take the medicines late that day. I should take a medicine like methadone 3 times a day, because the effects of the tablet lasts around 8 hours. But I take them every 12 hours, to have a low consumption in case doctors prescribe them too late (which happens, and then it's good to have a spouse going to the pharmacy buying them for you, because you have too much pain to go yourself).

    Since methadone is also used for treating heroine addicts, medical staff treat you with disrespect when they see that it says "methadone" in your health record. I need to show a certificate that says that I deal with chronic neuropathic pain, that I never have had problems with drug addiction, to get normal respect.

    I wanted to share this because I think I am alone in the world with these medicines in combination against neuropathic pain caused by hypermobile joints, joint dislocation and muscle spasms. After trying almost everything else, including surgery cutting nerves, methadone, clonazepam and Lyrica seems to be the only way to kill my pain. But it's a life where you always is questioned, because of the use of methadone. I can guarantee that everybody in the world should accept these medicines if they had experienced the unbearable pain I had in upper back before they started to give me clonazepam and methadone.
  • Had nms in 2005, will trileptal increase chance of recurrence?
    In 2005 I had NMS, which was not detected by my drs for 4 months. I'd been on Lexapro & Seroquel for 2 yrs, but was weaned from Lexapro & placed on Lamictal 3/05. Began getting low-grade fevers, which I was told were not caused by the Lamictal. I quit taking it anyway, fevers (along with uncontrollable shivering) continued & got higher. By 5/05 my temps were reaching 105 deg F. Husband said I became combative, refused to go to hospital. Early June/05 he came home to find me wrapped in blankets, with a temp over 105 F. He tried to place me in a tub of cold water, said I was rigid & screamed when he tried to move me. I was in the tub, speaking "in tongues" (his description, I have no memory of this). He called 911, took me to hospital. I woke, no idea where I was or why. After a lumbar puncture & 2 days in ICU I went home. The fevers continued...2 weeks later he came home to find me wrapped in sheets, towels, blankets, with the heat on full (it was in the 90's outside) he called ambulance again. I awoke to find myself under an ice blanket with nurses pushing large vials of dantrolene into both arms, several liters. Another LP, a stint in ICU...this time they told me it was NMS. The dr who dxd me said he was surprised I was alive, & not a vegetable, as my temp had peaked at 109 deg F. I suffered brain damage; short-term memory loss, brain can't control my body temp, my blood pressure went up. An arteriogram showed completely healthy heart & arteries, no plaque at all. I lost all body fat as well as some muscle mass. The fevers continued even after stopping the Seroquel. I visited my PCP for a checkup in 9/05, temp was normal. I started shuddering, my temp went up a full degree every 5 minutes. PCP admitted me to ER, my heart rate was over 272 B/M; they stopped my heart 3 times to "reset" it, which didn't work. I spent 3 days in hospital. Several months later my P doc tried me on Lamictal alone; I got Stevens-Johnson syndrome. I stopped the drug as soon as the signs appeared. I've been untreated, except for Neurontin & Primidone, until my manic episodes became unlivable. 3 weeks ago I went 8 days with no sleep, became psychotic. My P doc gave me Trileptal, which has evened my moods, but I've been getting low-grade fevers (highest was 103.6). Would having had NMS in the past make me more prone to falling to it again with the Trileptal? It's the only new med I've taken in over a year.

More reviews for: Clonidine, Klonopin, Lexapro, Mirapex

Comments from related studies:

  • From this study (2 weeks ago):

  • I am a 48 yr old female diagnosed with PTSD, bipolar 2, BPD, histrionic suicidal idealation and a mess!!!

    Things were going well in therapy and with my Dr. over the past 2 years on the above "cocktail" MINUS the Latuda and Lexapro.

    I have had 3 very serious suicide attempts, all prior to the Tegretol /Prozac regime.

    I do not want to change meds! Prior to the Tegretol, Klonopin , Lamictal , Prozac, Trazodone routine, I had made 3 very serious suicide attempts. The last leaving me with liver and kidney disease.

    I've recently been left with two tragic yet situational on sets. So against my desire, I agreed to omit Prozac and replace with Lexapro and add Latuda, replacing Tegretol.

    I have not been this unbalanced for YEARS! I know my triggers with suicide and believe that is the only reason I'm still alive. I HAD NOT THOUGHT ABOUT suicide for EIGHT YEARS!

    Crying all the time, don't eat or sleep for sometimes, up to four days! I'm so tired, I just cry more from frustration of not being able to sleep.

    I see my therapist tomorrow, but am on the "call" list for my Dr.

    With the holidays among us, I do not nor do I think I can make it on these meds.

    Can you PLEASE TELL ME if you know and I wasn't told, the, if any benefits will come forth? I know we are all different and I do trust my Md. Just not this time. Please, please help. Thank you.

    Reply

  • From this study (4 months ago):

  • VYVANSE IN DATIME
    OTHERS AT NIGHT

    Reply

  • From this study (4 months ago):

  • I have Raynaud's syndrome, but even while in the office, my arms feel like they are immersed in ice water; my right leg will periodically "buckle" and wobble at the knee while I'm standing at a kitchen counter getting my food ready; my alarm goes off at 6:30, and about 2 days during the week, I hit the snooze button the max # of times and am late for work

    Reply

    Sara on Aug, 19, 2014:

    I have sydenhams, dystonia and raynards. I have all from rhuematic fever, once you get one autoimmune disease my specialist says its not unusual to get others... the only thing that helps is living in Spain and in the winter gloves and socks!

    Reply

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