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Review: Lexapro and Savella

This review analyzes the effectiveness and drug interactions between Lexapro and Savella. It is created by eHealthMe based on reports of 70 people who take the same drugs from FDA and social media, and is updated regularly.

Stay connected: join a mobile support group for people who take Lexapro and Savella >>>

What are the drugs

Lexapro (latest outcomes from 39,276 users) has active ingredients of escitalopram oxalate. It is often used in depression.

Savella (latest outcomes from 3,371 users) has active ingredients of milnacipran hydrochloride. It is often used in fibromyalgia.

On Jul, 14, 2014: 70 people who take Lexapro, Savella are studied

Lexapro, Savella outcomes

Drug combinations in study:
- Lexapro (escitalopram oxalate)
- Savella (milnacipran hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Lexapro is effective0.00%
(0 of 2 people)
(2 of 2 people)
(0 of 1 people)
(0 of 2 people)
(0 of 1 people)
(0 of 1 people)
Savella is effective0.00%
(0 of 3 people)
(2 of 2 people)
(0 of 1 people)
(0 of 2 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
HyperhidrosisDepressionn/aAnxiety AggravatedParanoian/an/aNausea
NauseaPanic AttackPanic AttackHyperhidrosis
Abdominal PainParanoiaPyrexiaPalpitations
Panic AttackSomnolenceAggressionDyspnoea
LeukocytosisSuicidal IdeationUrinary Tract InfectionDecreased Appetite
Suicidal IdeationUrinary Tract InfectionSuicidal IdeationIleus
Feeling AbnormalTinnitusHyperreflexiaStupor
PalpitationsHyperreflexiaSomnolenceActivities Of Daily Living Impaired

Drug effectiveness by gender :

Lexapro is effective22.22%
(2 of 9 people)
Savella is effective25.00%
(2 of 8 people)

Most common drug interactions by gender * :

NauseaSuicidal Ideation
IleusUrinary Tract Infection
LeukocytosisDecreased Appetite
Impaired Driving AbilityParanoia
Abdominal PainTinnitus

Drug effectiveness by age :

Lexapro is effectiven/an/an/an/a50.00%
(2 of 4 people)
(0 of 1 people)
(0 of 4 people)
Savella is effectiven/an/an/an/a50.00%
(2 of 4 people)
(0 of 4 people)

Most common drug interactions by age * :

n/an/an/aAggressionDecreased AppetitePalpitationsHyperhidrosisDyspnoea
Panic AttackDiarrhoeaDyspnoeaNauseaCough
ManiaNauseaAnaphylactic ReactionFatigueInfusion Related Reaction
PyrexiaHyperkalaemiaAnaphylactic ShockIleusLocal Swelling
SomnolenceFatigueTremorLeukocytosisOedema Peripheral
Urinary Tract InfectionLatent TuberculosisDiarrhoeaActivities Of Daily Living ImpairedAsthenia
TinnitusAlanine Aminotransferase IncreasedFeeling AbnormalAbdominal PainSwelling Face
Suicidal IdeationBlood Triglycerides IncreasedPeripheral ColdnessStuporSwollen Tongue
HyperreflexiaExtrapyramidal DisorderAnxietyImpaired Driving AbilityDepression
ParanoiaAspartate Aminotransferase IncreasedBlood Pressure DecreasedOesophagitisHot Flush

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Get connected! Join a mobile support group:
- group for people who take Lexapro and Savella
- group for people who take Lexapro
- group for people who take Savella

Comments from related studies:

  • From this study (3 years ago):

  • I was wanting to see if there were any adverse reactions in taking all of these at the same time. Worried about my sister. The drug names are all correct, reason for each is unknown, I do know she has been having migraines.


Can you answer these questions (what is this?):

More questions for: Lexapro, Savella

You may be interested at these reviews (what is this?):

  • Yes, lexapro does cause tinnitus!
    Whenever I forget to take my Lexapro in the morning, I get a high pitched ringing in my ears which starts around 1:00 pm, which won't go away until a few hours after I take the drug. Once I was out of the medication and I almost screamed because the ringing got so bad! I don't think it is as "rare" ...

  • Lithium constipation and tremor
    After taking Lithium Carb for about three months, I realize I've been moderately constipated for several weeks. I also have been nauseous and suddenly realize that it's probably related to the nausea and maybe the cause of it.

  • Fibromyalgia & related health issues
    Fibromyalgia dx after pregnancy of only child at 42/other dx followed and seem to be in conjunction. heart issues did not appear until after the use of fibro meds- cymbalta, lyrica, neurontin, and more. had 1 seizure believed to be related to seretonin syndrome/years and years of mistreatment by doc ...

More reviews for: Lexapro, Savella

Complete drug side effects:

On eHealthMe, Lexapro (escitalopram oxalate) is often used to treat depression. Savella (milnacipran hydrochloride) is often used to treat fibromyalgia. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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