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Review: taking Lexapro and Seroquel Xr together

Summary: drug interactions are reported among people who take Lexapro and Seroquel Xr together.

This review analyzes the effectiveness and drug interactions between Lexapro and Seroquel Xr. It is created by eHealthMe based on reports of 4,153 people who take the same drugs from FDA and social media, and is updated regularly.


You are not alone: join a support group for people who take Lexapro and Seroquel Xr >>>

On Mar, 27, 2015: 4,153 people who take Lexapro, Seroquel Xr are studied

Lexapro, Seroquel Xr outcomes

Drug combinations in study:
- Lexapro (escitalopram oxalate)
- Seroquel Xr (quetiapine fumarate)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Lexapro is effective16.67%
(3 of 18 people)
(11 of 33 people)
(10 of 23 people)
(7 of 29 people)
(13 of 37 people)
(6 of 16 people)
(1 of 10 people)
(0 of 3 people)
Seroquel Xr is effective16.00%
(4 of 25 people)
(11 of 32 people)
(10 of 20 people)
(17 of 37 people)
(20 of 30 people)
(11 of 17 people)
(1 of 4 people)
(1 of 2 people)

Drug effectiveness by gender :

Lexapro is effective36.79%
(39 of 106 people)
(12 of 63 people)
Seroquel Xr is effective45.71%
(48 of 105 people)
(27 of 62 people)

Drug effectiveness by age :

Lexapro is effective0.00%
(0 of 1 people)
(3 of 35 people)
(13 of 48 people)
(12 of 65 people)
(11 of 54 people)
(8 of 51 people)
(4 of 31 people)
Seroquel Xr is effective100.00%
(1 of 1 people)
(4 of 34 people)
(14 of 50 people)
(19 of 65 people)
(18 of 53 people)
(14 of 50 people)
(5 of 32 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Type 2 Diabetes MellitusType 2 Diabetes MellitusType 2 Diabetes MellitusType 2 Diabetes MellitusType 2 Diabetes MellitusType 2 Diabetes MellitusDizzinessDiabetes Mellitus
Suicidal IdeationDiabetes MellitusDiabetes MellitusDiabetes MellitusDiabetes MellitusDiabetes MellitusType 2 Diabetes MellitusType 2 Diabetes Mellitus
SomnolenceInsomniaObesityObesitySuicidal IdeationBlood Cholesterol IncreasedDiabetes MellitusWeight Increased
ConvulsionDiabetes Mellitus Inadequate ControlWeight IncreasedBlood Cholesterol IncreasedDepressionObesityAstheniaDepression
DepressionBlood Cholesterol IncreasedDiabetes Mellitus Inadequate ControlHyperglycaemiaBlood Cholesterol IncreasedHyperlipidaemiaSomnolenceBlood Cholesterol Increased
AgitationSuicide AttemptInsomniaPancreatitisPancreatitisDiabetes Mellitus Inadequate ControlBlood Cholesterol IncreasedAnxiety
Suicide AttemptHeadacheDiabetic KetoacidosisAnxietyObesityNeuropathy PeripheralDehydrationSuicidal Ideation
Blood Cholesterol IncreasedType 1 Diabetes MellitusSuicidal IdeationDepressionSuicide AttemptSuicidal IdeationCholelithiasisPancreatitis
OverdoseWeight IncreasedDepressionWeight IncreasedInsomniaBlood Triglycerides IncreasedUrinary Tract InfectionInsomnia
Diabetes MellitusOverdoseBlood Cholesterol IncreasedDiabetes Mellitus Inadequate ControlWeight IncreasedHeadacheHypercholesterolaemiaDiabetes Mellitus Inadequate Control

Most common drug interactions by gender * :

Diabetes MellitusDiabetes Mellitus
Type 2 Diabetes MellitusType 2 Diabetes Mellitus
DepressionSuicidal Ideation
Weight IncreasedAnxiety
Blood Cholesterol IncreasedDepression
PancreatitisBlood Cholesterol Increased
ObesityWeight Increased
Diabetes Mellitus Inadequate ControlSuicide Attempt

Most common drug interactions by age * :

Diabetes MellitusSuicidal IdeationWeight IncreasedDiabetes MellitusDiabetes MellitusDiabetes MellitusDiabetes MellitusAnxiety
PancreatitisDiarrhoeaSuicidal IdeationType 2 Diabetes MellitusType 2 Diabetes MellitusType 2 Diabetes MellitusType 2 Diabetes MellitusDepression
Suicidal IdeationMood SwingsDiabetes MellitusWeight IncreasedWeight IncreasedBlood Cholesterol IncreasedBlood Cholesterol IncreasedConfusional State
Ovarian CystAbnormal BehaviourSomnolenceHeadacheBlood Cholesterol IncreasedDiabetes Mellitus Inadequate ControlAnxietySuicidal Ideation
Suicide AttemptTicManiaDyspnoeaObesityNeuropathy PeripheralDepressionDiabetes Mellitus
Type 2 Diabetes MellitusSuicide AttemptBipolar DisorderInsomniaDiabetes Mellitus Inadequate ControlWeight IncreasedInsomniaDiarrhoea
Extrapyramidal DisorderAnxietyDepressionAbdominal PainDepressionPancreatitisHyperglycaemiaPain
Intentional OverdoseAngerGallbladder DisorderVomitingSuicidal IdeationObesityNauseaWeight Decreased
DepressionCryingDiabetic KetoacidosisDizzinessPancreatitisDepressionWeight IncreasedFall
Gastrointestinal HaemorrhageAggressionFatigueSuicidal IdeationDiabetic NeuropathyHyperlipidaemiaSomnolenceType 2 Diabetes Mellitus

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Lexapro and Seroquel Xr?




You are not alone! Join a related support group:
- support group for people who take Lexapro
- support group for people who take Seroquel Xr

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Lexapro (escitalopram oxalate) is often used to treat depression. Seroquel Xr (quetiapine fumarate) is often used to treat bipolar disorder. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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